{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T17:39:49Z","timestamp":1790185189601,"version":"4.1.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,10,17]],"date-time":"2016-10-17T00:00:00Z","timestamp":1476662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["ajkd.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Kidney Diseases"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1053\/j.ajkd.2016.08.028","type":"journal-article","created":{"date-parts":[[2016,11,14]],"date-time":"2016-11-14T11:52:26Z","timestamp":1479124346000},"page":"210-219","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["Tolvaptan and Kidney Pain in Patients With Autosomal Dominant\u00a0Polycystic Kidney Disease: Secondary Analysis From\u00a0a Randomized Controlled Trial"],"prefix":"10.1053","volume":"69","author":[{"given":"Niek F.","family":"Casteleijn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime D.","family":"Blais","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arlene B.","family":"Chapman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank S.","family":"Czerwiec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Devuyst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eiji","family":"Higashihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna M.","family":"Leliveld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Ouyang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald D.","family":"Perrone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicente E.","family":"Torres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ron T.","family":"Gansevoort","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1053\/j.ajkd.2016.08.028_bib1","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1046\/j.1523-1755.2001.00985.x","article-title":"Pain management in polycystic kidney disease","volume":"60","author":"Bajwa","year":"2001","journal-title":"Kidney Int"},{"issue":"3","key":"10.1053\/j.ajkd.2016.08.028_bib2","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1053\/j.ackd.2010.01.005","article-title":"Evaluation and management of pain in autosomal dominant polycystic kidney disease","volume":"17","author":"Hogan","year":"2010","journal-title":"Adv Chronic Kidney Dis"},{"issue":"suppl 4","key":"10.1053\/j.ajkd.2016.08.028_bib3","doi-asserted-by":"crossref","first-page":"iv142","DOI":"10.1093\/ndt\/gfu073","article-title":"A\u00a0stepwise approach for effective management of chronic pain in autosomal-dominant polycystic kidney disease","volume":"29","author":"Casteleijn","year":"2014","journal-title":"Nephrol Dial Transplant"},{"issue":"5","key":"10.1053\/j.ajkd.2016.08.028_bib4","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1056\/NEJM199307293290508","article-title":"Autosomal dominant polycystic kidney disease","volume":"329","author":"Gabow","year":"1993","journal-title":"N\u00a0Engl J Med"},{"issue":"25","key":"10.1053\/j.ajkd.2016.08.028_bib5","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1056\/NEJMoa1205511","article-title":"Tolvaptan in patients with autosomal dominant polycystic kidney disease","volume":"367","author":"Torres","year":"2012","journal-title":"N\u00a0Engl J Med"},{"issue":"5","key":"10.1053\/j.ajkd.2016.08.028_bib6","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1053\/j.ajkd.2010.11.029","article-title":"Rationale and design of the TEMPO (Tolvaptan Efficacy and Safety in Management of Autosomal Dominant Polycystic Kidney Disease and Its Outcomes) 3-4 study","volume":"57","author":"Torres","year":"2011","journal-title":"Am J Kidney Dis"},{"issue":"1","key":"10.1053\/j.ajkd.2016.08.028_bib7","first-page":"e60","article-title":"CONSORT 2010 statement: updated guidelines for reporting parallel group randomized trials","volume":"4","author":"Schulz","year":"2010","journal-title":"Open Med"},{"issue":"9","key":"10.1053\/j.ajkd.2016.08.028_bib8","doi-asserted-by":"crossref","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","article-title":"A\u00a0new equation to estimate glomerular filtration rate","volume":"150","author":"Levey","year":"2009","journal-title":"Ann Intern Med"},{"issue":"4","key":"10.1053\/j.ajkd.2016.08.028_bib9","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1111\/j.1523-1755.2004.00921.x","article-title":"Pain patterns in patients with polycystic kidney disease","volume":"66","author":"Bajwa","year":"2004","journal-title":"Kidney Int"},{"issue":"4","key":"10.1053\/j.ajkd.2016.08.028_bib10","first-page":"220","article-title":"Health-related quality of life in patients with autosomal dominant polycystic kidney disease and CKD stages 1-4: a cross-sectional study","volume":"63","author":"Miskulin","year":"2013","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/j.ajkd.2016.08.028_bib11","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1186\/1471-2369-14-179","article-title":"Quality of life of patients with ADPKD-toranomon PKD QOL study: cross-sectional study","volume":"14","author":"Suwabe","year":"2013","journal-title":"BMC Nephrol"},{"issue":"3","key":"10.1053\/j.ajkd.2016.08.028_bib12","doi-asserted-by":"crossref","first-page":"560","DOI":"10.2215\/CJN.02410508","article-title":"Quality of life in autosomal dominant polycystic kidney disease patients not yet on dialysis","volume":"4","author":"Rizk","year":"2009","journal-title":"Clin J Am Soc Nephrol"},{"issue":"1","key":"10.1053\/j.ajkd.2016.08.028_bib13","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1093\/bja\/aet127","article-title":"Sex differences in pain: a brief review of clinical and experimental findings","volume":"111","author":"Bartley","year":"2013","journal-title":"Br J Anaesth"},{"issue":"2","key":"10.1053\/j.ajkd.2016.08.028_bib14","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1007\/s12630-013-0087-4","article-title":"The transition from acute to chronic pain: understanding how different biological systems interact","volume":"61","author":"Mifflin","year":"2014","journal-title":"Can J Anaesth"},{"issue":"10","key":"10.1053\/j.ajkd.2016.08.028_bib15","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1111\/liv.12430","article-title":"Evaluating health-related quality of life in patients with polycystic liver disease and determining the impact of symptoms and liver volume","volume":"34","author":"Wijnands","year":"2014","journal-title":"Liver Int"},{"issue":"suppl 1","key":"10.1053\/j.ajkd.2016.08.028_bib16","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1097\/MNH.0b013e328360a268","article-title":"Impact of fluid intake in the prevention of urinary system diseases: a brief review","volume":"22","author":"Lotan","year":"2013","journal-title":"Curr Opin Nephrol Hypertens"},{"issue":"6","key":"10.1053\/j.ajkd.2016.08.028_bib17","first-page":"499","article-title":"The effect of fluid intake on chronic kidney transplant failure: a pilot study","volume":"21","author":"Magpantay","year":"2011","journal-title":"J\u00a0Ren Nutr"},{"issue":"6","key":"10.1053\/j.ajkd.2016.08.028_bib18","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1038\/ki.2013.285","article-title":"Short-term renal hemodynamic effects of tolvaptan in subjects with autosomal dominant polycystic kidney disease at various stages of chronic kidney disease","volume":"84","author":"Boertien","year":"2013","journal-title":"Kidney Int"},{"issue":"1","key":"10.1053\/j.ajkd.2016.08.028_bib19","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1161\/CIRCHEARTFAILURE.112.970012","article-title":"Association of arginine vasopressin levels with outcomes and the effect of V2 blockade in patients hospitalized for heart failure with reduced ejection fraction: insights from the EVEREST trial","volume":"6","author":"Lanfear","year":"2013","journal-title":"Circ Heart Fail"},{"issue":"5","key":"10.1053\/j.ajkd.2016.08.028_bib20","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/0361-9230(92)90122-E","article-title":"Protein kinase C activators stimulate beta-endorphin secretion from hypothalamic cells","volume":"29","author":"Kapcala","year":"1992","journal-title":"Brain Res Bull"},{"issue":"1","key":"10.1053\/j.ajkd.2016.08.028_bib21","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1254\/jphs.08R18FM","article-title":"New topics in vasopressin receptors and approach to novel drugs: vasopressin and pain perception","volume":"109","author":"Koshimizu","year":"2009","journal-title":"J\u00a0Pharmacol Sci"}],"container-title":["American Journal of Kidney Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272638616305170?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272638616305170?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T02:56:27Z","timestamp":1759460187000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0272638616305170"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["S0272638616305170"],"URL":"https:\/\/doi.org\/10.1053\/j.ajkd.2016.08.028","relation":{},"ISSN":["0272-6386"],"issn-type":[{"value":"0272-6386","type":"print"}],"subject":[],"published":{"date-parts":[[2017,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Tolvaptan and Kidney Pain in Patients With Autosomal Dominant\u00a0Polycystic Kidney Disease: Secondary Analysis From\u00a0a Randomized Controlled Trial","name":"articletitle","label":"Article Title"},{"value":"American Journal of Kidney Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.ajkd.2016.08.028","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 The Authors. Published by Elsevier Inc. on behalf of the National Kidney Foundation, Inc.","name":"copyright","label":"Copyright"}]}}