{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T23:45:48Z","timestamp":1793231148482,"version":"4.5.0"},"reference-count":128,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"crossref","award":["K23-DK099442"],"award-info":[{"award-number":["K23-DK099442"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["ajkd.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Kidney Diseases"],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.1053\/j.ajkd.2017.01.051","type":"journal-article","created":{"date-parts":[[2017,4,18]],"date-time":"2017-04-18T00:30:18Z","timestamp":1492475418000},"page":"837-852","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":205,"title":["Exercise and CKD: Skeletal Muscle Dysfunction and Practical Application of Exercise to Prevent and Treat Physical Impairments in CKD"],"prefix":"10.1053","volume":"69","author":[{"given":"Baback","family":"Roshanravan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Gamboa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth","family":"Wilund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1053\/j.ajkd.2017.01.051_bib1","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1097\/MNH.0b013e328365b43a","article-title":"The association of physical activity and physical function with clinical outcomes in adults with chronic kidney disease","volume":"22","author":"Painter","year":"2013","journal-title":"Curr Opin Nephrol Hypertens"},{"issue":"8","key":"10.1053\/j.ajkd.2017.01.051_bib2","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1681\/ASN.2013080835","article-title":"Quality of life and outcomes in African Americans with CKD","volume":"25","author":"Porter","year":"2014","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"5","key":"10.1053\/j.ajkd.2017.01.051_bib3","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1681\/ASN.2012070702","article-title":"Association between physical performance and all-cause mortality in CKD","volume":"24","author":"Roshanravan","year":"2013","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"6","key":"10.1053\/j.ajkd.2017.01.051_bib4","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1053\/j.ajkd.2012.05.017","article-title":"A\u00a0prospective study of frailty in nephrology-referred patients with CKD","volume":"60","author":"Roshanravan","year":"2012","journal-title":"Am J Kidney Dis"},{"issue":"2","key":"10.1053\/j.ajkd.2017.01.051_bib5","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1053\/j.ajkd.2010.08.016","article-title":"Association of CKD with disability in the United States","volume":"57","author":"Plantinga","year":"2011","journal-title":"Am J Kidney Dis"},{"issue":"3","key":"10.1053\/j.ajkd.2017.01.051_bib6","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1093\/gerona\/glt096","article-title":"Chronic kidney disease defined by cystatin C predicts mobility disability and changes in gait speed: the Framingham Offspring Study","volume":"69","author":"Liu","year":"2014","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"key":"10.1053\/j.ajkd.2017.01.051_bib7","series-title":"The Epidemiology of Aging","author":"Newman","year":"2012"},{"key":"10.1053\/j.ajkd.2017.01.051_bib8","first-page":"1018A","article-title":"Lower eGFR is associated with worse muscle fatigue and muscle quality among older adults","volume":"25","author":"Roshanravan","year":"2014","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"4","key":"10.1053\/j.ajkd.2017.01.051_bib9","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1111\/j.1525-139X.2010.00763.x","article-title":"Insulin resistance and protein energy metabolism in patients with advanced chronic kidney disease","volume":"23","author":"Siew","year":"2010","journal-title":"Semin Dial"},{"issue":"7","key":"10.1053\/j.ajkd.2017.01.051_bib10","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1056\/NEJMoa031314","article-title":"Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes","volume":"350","author":"Petersen","year":"2004","journal-title":"N\u00a0Engl J Med"},{"issue":"5","key":"10.1053\/j.ajkd.2017.01.051_bib11","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.2337\/db06-0783","article-title":"Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients","volume":"56","author":"Befroy","year":"2007","journal-title":"Diabetes"},{"issue":"2","key":"10.1053\/j.ajkd.2017.01.051_bib12","doi-asserted-by":"crossref","first-page":"R337","DOI":"10.1152\/ajpregu.00469.2004","article-title":"Mechanisms of disuse muscle atrophy: role of oxidative stress","volume":"288","author":"Powers","year":"2005","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"9","key":"10.1053\/j.ajkd.2017.01.051_bib13","doi-asserted-by":"crossref","first-page":"2519","DOI":"10.1089\/ars.2011.3973","article-title":"Mechanistic links between oxidative stress and disuse muscle atrophy","volume":"15","author":"Powers","year":"2011","journal-title":"Antioxid Redox Signal"},{"issue":"4","key":"10.1053\/j.ajkd.2017.01.051_bib14","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1093\/gerona\/gls196","article-title":"Skeletal muscle mitochondrial energetics are associated with maximal aerobic capacity and walking speed in older adults","volume":"68","author":"Coen","year":"2013","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"issue":"11","key":"10.1053\/j.ajkd.2017.01.051_bib15","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1093\/gerona\/glu134","article-title":"Skeletal muscle mitochondrial function and fatigability in older adults","volume":"70","author":"Santanasto","year":"2014","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"issue":"1","key":"10.1053\/j.ajkd.2017.01.051_bib16","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1681\/ASN.V6168","article-title":"Effects of chronic renal failure on enzymes of energy metabolism in individual human muscle fibers","volume":"6","author":"Conjard","year":"1995","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"2","key":"10.1053\/j.ajkd.2017.01.051_bib17","doi-asserted-by":"crossref","first-page":"E219","DOI":"10.1152\/ajpendo.2000.278.2.E219","article-title":"Reduced synthesis of muscle proteins in chronic renal failure","volume":"278","author":"Adey","year":"2000","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"6","key":"10.1053\/j.ajkd.2017.01.051_bib18","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1093\/ndt\/gfh189","article-title":"Abnormal mitochondrial function and muscle wasting, but normal contractile efficiency, in haemodialysed patients studied non-invasively in\u00a0vivo","volume":"19","author":"Kemp","year":"2004","journal-title":"Nephrol Dial Transplant"},{"issue":"9","key":"10.1053\/j.ajkd.2017.01.051_bib19","doi-asserted-by":"crossref","DOI":"10.14814\/phy2.12780","article-title":"Mitochondrial dysfunction and oxidative stress in patients with chronic kidney disease","volume":"4","author":"Gamboa","year":"2016","journal-title":"Physiol Rep"},{"issue":"4","key":"10.1053\/j.ajkd.2017.01.051_bib20","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1053\/j.ajkd.2016.05.011","article-title":"CKD and muscle mitochondrial energetics","volume":"68","author":"Roshanravan","year":"2016","journal-title":"Am J Kidney Dis"},{"issue":"11","key":"10.1053\/j.ajkd.2017.01.051_bib21","doi-asserted-by":"crossref","first-page":"e26963","DOI":"10.1371\/journal.pone.0026963","article-title":"Reduced coupling of oxidative phosphorylation in\u00a0vivo precedes electron transport chain defects due to mild oxidative stress in mice","volume":"6","author":"Siegel","year":"2011","journal-title":"PLoS One"},{"issue":"9-10","key":"10.1053\/j.ajkd.2017.01.051_bib22","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/j.mad.2012.08.002","article-title":"Impaired adaptability of in\u00a0vivo mitochondrial energetics to acute oxidative insult in aged skeletal muscle","volume":"133","author":"Siegel","year":"2012","journal-title":"Mech Ageing Dev"},{"issue":"3","key":"10.1053\/j.ajkd.2017.01.051_bib23","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1113\/expphysiol.2012.067314","article-title":"Exercise efficiency is reduced by mitochondrial uncoupling in the elderly","volume":"98","author":"Conley","year":"2013","journal-title":"Exp Physiol"},{"issue":"6","key":"10.1053\/j.ajkd.2017.01.051_bib24","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1038\/ki.2013.473","article-title":"Chronic kidney disease reduces muscle mitochondria and exercise endurance and its exacerbation by dietary protein through inactivation of pyruvate dehydrogenase","volume":"85","author":"Tamaki","year":"2014","journal-title":"Kidney Int"},{"issue":"5","key":"10.1053\/j.ajkd.2017.01.051_bib25","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1093\/gerona\/glu010","article-title":"The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates","volume":"69","author":"Studenski","year":"2014","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"issue":"5","key":"10.1053\/j.ajkd.2017.01.051_bib26","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1093\/gerona\/glu012","article-title":"Criteria for clinically relevant weakness and low lean mass and their longitudinal association with incident mobility impairment and mortality: the Foundation for the National Institutes of Health (FNIH) Sarcopenia Project","volume":"69","author":"McLean","year":"2014","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"issue":"10","key":"10.1053\/j.ajkd.2017.01.051_bib27","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.2215\/CJN.10261013","article-title":"Comparative associations of muscle mass and muscle strength with mortality in dialysis patients","volume":"9","author":"Isoyama","year":"2014","journal-title":"Clin J Am Soc Nephrol"},{"issue":"2","key":"10.1053\/j.ajkd.2017.01.051_bib28","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1053\/j.ajkd.2015.01.024","article-title":"Gait speed and mortality, hospitalization, and functional status change among hemodialysis patients: a US Renal Data System special study","volume":"66","author":"Kutner","year":"2015","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/j.ajkd.2017.01.051_bib29","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1093\/aje\/kwj333","article-title":"Cystatin C and measures of physical function in elderly adults. The Health, Aging, and Body\u00a0Composition (HABC) Study","volume":"164","author":"Odden","year":"2006","journal-title":"Am J Epidemiol"},{"issue":"5","key":"10.1053\/j.ajkd.2017.01.051_bib30","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1111\/j.1532-5415.2006.00727.x","article-title":"Chronic kidney disease and functional limitation in older people: Health, Aging and Body Composition Study","volume":"54","author":"Fried","year":"2006","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"5","key":"10.1053\/j.ajkd.2017.01.051_bib31","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1053\/j.ajkd.2014.10.016","article-title":"Creatinine clearance, walking speed, and muscle atrophy: a cohort study","volume":"65","author":"Roshanravan","year":"2015","journal-title":"Am J Kidney Dis"},{"issue":"3","key":"10.1053\/j.ajkd.2017.01.051_bib32","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1093\/gerona\/60.3.324","article-title":"Muscle mass, muscle strength, and muscle fat infiltration as predictors of incident mobility limitations in well-functioning older persons","volume":"60","author":"Visser","year":"2005","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"issue":"8","key":"10.1053\/j.ajkd.2017.01.051_bib33","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1093\/gerona\/glv016","article-title":"Muscle quality and\u00a0muscle fat infiltration in relation to incident mobility disability\u00a0and gait speed decline: the Age, Gene\/Environment Susceptibility-Reykjavik Study","volume":"70","author":"Reinders","year":"2015","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"issue":"2","key":"10.1053\/j.ajkd.2017.01.051_bib34","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1093\/gerona\/glw210","article-title":"Association of muscle endurance, fatigability, and strength with functional limitation and mortality in the Health Aging and Body Composition Study","volume":"72","author":"Roshanravan","year":"2017","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"key":"10.1053\/j.ajkd.2017.01.051_bib35","first-page":"806","article-title":"Lower muscle endurance, strength and quality are associated with greater risk of functional limitations in older adults with CKD","volume":"26","author":"Roshanravan","year":"2015","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"10","key":"10.1053\/j.ajkd.2017.01.051_bib36","doi-asserted-by":"crossref","first-page":"e0165400","DOI":"10.1371\/journal.pone.0165400","article-title":"Association of fluid status and body composition with physical function in patients with chronic kidney disease","volume":"11","author":"Hsiao","year":"2016","journal-title":"PLoS One"},{"key":"10.1053\/j.ajkd.2017.01.051_bib37","unstructured":"Centers for Disease Control and Prevention. STEADI Materials for Health Care Providers. http:\/\/www.cdc.gov\/steadi\/materials.html. Accessed February21,\u00a02017."},{"issue":"12","key":"10.1053\/j.ajkd.2017.01.051_bib38","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.2522\/ptj.20100417","article-title":"Performance-based versus patient-reported physical function: what are the underlying predictors?","volume":"91","author":"Bean","year":"2011","journal-title":"Phys Ther"},{"issue":"1","key":"10.1053\/j.ajkd.2017.01.051_bib39","doi-asserted-by":"crossref","first-page":"M43","DOI":"10.1093\/gerona\/55.1.M43","article-title":"Preclinical mobility disability predicts incident mobility disability in older women","volume":"55","author":"Fried","year":"2000","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"issue":"3","key":"10.1053\/j.ajkd.2017.01.051_bib40","doi-asserted-by":"crossref","first-page":"e329","DOI":"10.1016\/j.archger.2011.08.018","article-title":"Incident preclinical mobility disability (PCMD) increases future risk of new difficulty walking and reduction in walking activity","volume":"54","author":"Weiss","year":"2012","journal-title":"Arch Gerontol Geriatr"},{"issue":"11","key":"10.1053\/j.ajkd.2017.01.051_bib41","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1001\/jama.2013.276566","article-title":"Mobility limitation in the older patient: a clinical review","volume":"310","author":"Brown","year":"2013","journal-title":"JAMA"},{"issue":"1","key":"10.1053\/j.ajkd.2017.01.051_bib42","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1001\/jama.2010.1923","article-title":"Gait speed and survival in older adults","volume":"305","author":"Studenski","year":"2011","journal-title":"JAMA"},{"issue":"9","key":"10.1053\/j.ajkd.2017.01.051_bib43","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1056\/NEJM199503023320902","article-title":"Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability","volume":"332","author":"Guralnik","year":"1995","journal-title":"N\u00a0Engl J Med"},{"issue":"5","key":"10.1053\/j.ajkd.2017.01.051_bib44","doi-asserted-by":"crossref","first-page":"861","DOI":"10.2215\/CJN.06590712","article-title":"Assessing physical function and physical activity in patients with CKD","volume":"8","author":"Painter","year":"2013","journal-title":"Clin J Am Soc Nephrol"},{"issue":"3","key":"10.1053\/j.ajkd.2017.01.051_bib45","first-page":"M146","article-title":"Frailty in older adults: evidence for a phenotype","volume":"56A","author":"Fried","year":"2001","journal-title":"J\u00a0Gerontol"},{"issue":"6","key":"10.1053\/j.ajkd.2017.01.051_bib46","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1111\/jgs.12266","article-title":"Frailty as a novel predictor of mortality and hospitalization in individuals of all ages undergoing hemodialysis","volume":"61","author":"McAdams-DeMarco","year":"2013","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"11","key":"10.1053\/j.ajkd.2017.01.051_bib47","doi-asserted-by":"crossref","first-page":"2960","DOI":"10.1681\/ASN.2007020221","article-title":"Significance of frailty among dialysis patients","volume":"18","author":"Johansen","year":"2007","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"8","key":"10.1053\/j.ajkd.2017.01.051_bib48","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1111\/j.1532-5415.2007.01259.x","article-title":"Frailty in older men: prevalence, progression, and relationship with mortality","volume":"55","author":"Cawthon","year":"2007","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"12","key":"10.1053\/j.ajkd.2017.01.051_bib49","doi-asserted-by":"crossref","DOI":"10.1111\/j.1532-5415.2008.02008.x","article-title":"Prognostic significance of potential frailty criteria","volume":"56","author":"Rothman","year":"2008","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"2","key":"10.1053\/j.ajkd.2017.01.051_bib50","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1111\/j.1532-5415.2005.00586.x","article-title":"The dynamic nature of mobility disability in older persons","volume":"54","author":"Gill","year":"2006","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"4","key":"10.1053\/j.ajkd.2017.01.051_bib51","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1159\/000441575","article-title":"The frail dialysis population: a growing burden for the dialysis community","volume":"40","author":"Johansen","year":"2015","journal-title":"Blood Purif"},{"issue":"4","key":"10.1053\/j.ajkd.2017.01.051_bib52","doi-asserted-by":"crossref","first-page":"626","DOI":"10.2215\/CJN.03710415","article-title":"Association of performance-based and self-reported function-based definitions of frailty with mortality among patients receiving hemodialysis","volume":"11","author":"Johansen","year":"2016","journal-title":"Clin J Am Soc Nephrol"},{"issue":"1","key":"10.1053\/j.ajkd.2017.01.051_bib53","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1542-4758.2012.00719.x","article-title":"A\u00a0closer look at frailty in ESRD: getting the measure right","volume":"17","author":"Painter","year":"2013","journal-title":"Hemodial Int"},{"issue":"12","key":"10.1053\/j.ajkd.2017.01.051_bib54","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.2215\/CJN.02870313","article-title":"Kidney function and prevalent and incident frailty","volume":"8","author":"Dalrymple","year":"2013","journal-title":"Clin J Am Soc Nephrol"},{"issue":"6","key":"10.1053\/j.ajkd.2017.01.051_bib55","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a025916","article-title":"Interventions for human frailty: physical activity as a model","volume":"6","author":"Fried","year":"2016","journal-title":"Cold Spring Harb Perspect Med"},{"issue":"6","key":"10.1053\/j.ajkd.2017.01.051_bib56","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1093\/aje\/kws125","article-title":"Patterns of 12-year change in physical activity levels in community-dwelling older women: can modest levels of physical activity help older women live longer?","volume":"176","author":"Xue","year":"2012","journal-title":"Am J Epidemiol"},{"issue":"1","key":"10.1053\/j.ajkd.2017.01.051_bib57","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1748-1716.1977.tb10356.x","article-title":"Time course of changes in human skeletal muscle succinate dehydrogenase and cytochrome oxidase activities and maximal oxygen uptake with physical activity and inactivity","volume":"99","author":"Henriksson","year":"1977","journal-title":"Acta Physiol Scand"},{"issue":"pt 2","key":"10.1053\/j.ajkd.2017.01.051_bib58","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1242\/jeb.126623","article-title":"Mitochondria to motion: optimizing oxidative phosphorylation to improve exercise performance","volume":"219","author":"Conley","year":"2016","journal-title":"J\u00a0Exp Biol"},{"issue":"2","key":"10.1053\/j.ajkd.2017.01.051_bib59","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1152\/jappl.1985.59.2.320","article-title":"Endurance training in humans: aerobic capacity and structure of skeletal muscle","volume":"59","author":"Hoppeler","year":"1985","journal-title":"J\u00a0Appl Physiol"},{"issue":"11","key":"10.1053\/j.ajkd.2017.01.051_bib60","doi-asserted-by":"crossref","first-page":"965","DOI":"10.7326\/0003-4819-135-11-200112040-00008","article-title":"Resistance training to counteract the catabolism of a low-protein diet in patients with chronic renal insufficiency. A randomized, controlled trial","volume":"135","author":"Castaneda","year":"2001","journal-title":"Ann Intern Med"},{"issue":"8","key":"10.1053\/j.ajkd.2017.01.051_bib61","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1152\/japplphysiol.01084.2014","article-title":"Effect of endurance and\/or strength training on muscle fiber size, oxidative capacity, and capillarity in hemodialysis patients","volume":"119","author":"Lewis","year":"2015","journal-title":"J\u00a0Appl Physiol"},{"issue":"12","key":"10.1053\/j.ajkd.2017.01.051_bib62","doi-asserted-by":"crossref","first-page":"3769","DOI":"10.1681\/ASN.2015091034","article-title":"Neither hematocrit normalization nor exercise training restores oxygen consumption to normal levels in hemodialysis patients","volume":"27","author":"Stray-Gundersen","year":"2016","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"6","key":"10.1053\/j.ajkd.2017.01.051_bib63","doi-asserted-by":"crossref","first-page":"996","DOI":"10.2215\/CJN.09141209","article-title":"Resistance training increases muscle mitochondrial biogenesis in patients with chronic kidney disease","volume":"5","author":"Balakrishnan","year":"2010","journal-title":"Clin J Am Soc Nephrol"},{"issue":"9","key":"10.1053\/j.ajkd.2017.01.051_bib64","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1681\/ASN.2013070702","article-title":"Evidence for anti-inflammatory effects of exercise in CKD","volume":"25","author":"Viana","year":"2014","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"4-5","key":"10.1053\/j.ajkd.2017.01.051_bib65","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1159\/000431339","article-title":"The role of deconditioning in the end-stage renal disease myopathy: physical exercise improves altered resting muscle oxygen consumption","volume":"41","author":"Manfredini","year":"2015","journal-title":"Am J Nephrol"},{"issue":"23","key":"10.1053\/j.ajkd.2017.01.051_bib66","doi-asserted-by":"crossref","first-page":"2387","DOI":"10.1001\/jama.2014.5616","article-title":"Effect of structured physical activity on prevention of major mobility disability in older adults: the LIFE study randomized clinical trial","volume":"311","author":"Pahor","year":"2014","journal-title":"JAMA"},{"issue":"11","key":"10.1053\/j.ajkd.2017.01.051_bib67","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1093\/gerona\/glr123","article-title":"The Lifestyle Interventions and Independence for Elders Study: design and methods","volume":"66","author":"Fielding","year":"2011","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"issue":"5","key":"10.1053\/j.ajkd.2017.01.051_bib68","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1093\/gerona\/glw001","article-title":"Cost-effectiveness of the LIFE physical activity intervention for older adults at increased risk for mobility disability","volume":"71","author":"Groessl","year":"2016","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"issue":"3","key":"10.1053\/j.ajkd.2017.01.051_bib69","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1053\/j.ajkd.2014.03.020","article-title":"Exercise training in adults with CKD: a systematic review and meta-analysis","volume":"64","author":"Heiwe","year":"2014","journal-title":"Am J Kidney Dis"},{"issue":"8","key":"10.1053\/j.ajkd.2017.01.051_bib70","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1007\/s40279-014-0176-8","article-title":"Effect of progressive resistance training on measures of skeletal muscle hypertrophy, muscular strength and health-related quality of life in patients with chronic kidney disease: a systematic review and meta-analysis","volume":"44","author":"Cheema","year":"2014","journal-title":"Sports Med"},{"key":"10.1053\/j.ajkd.2017.01.051_bib71","first-page":"CD003236","article-title":"Exercise training for adults with chronic kidney disease","volume":"10","author":"Heiwe","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1053\/j.ajkd.2017.01.051_bib72","article-title":"Exercise in patients on dialysis: a multicenter, randomized clinical trial","author":"Manfredini","year":"2016","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"1","key":"10.1053\/j.ajkd.2017.01.051_bib73","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1111\/j.1525-139X.2009.00652.x","article-title":"Sustaining a hemodialysis exercise program: a review","volume":"23","author":"Bennett","year":"2010","journal-title":"Semin Dial"},{"issue":"1","key":"10.1053\/j.ajkd.2017.01.051_bib74","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1159\/000363599","article-title":"Self-reported physical activity in patients on chronic hemodialysis: correlates and barriers","volume":"38","author":"Bossola","year":"2014","journal-title":"Blood Purif"},{"issue":"1","key":"10.1053\/j.ajkd.2017.01.051_bib75","first-page":"23","article-title":"Perceived barriers and motivators to exercise in hemodialysis patients","volume":"31","author":"Goodman","year":"2004","journal-title":"Nephrol Nurs J"},{"issue":"3","key":"10.1053\/j.ajkd.2017.01.051_bib76","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1093\/ndt\/gfr404","article-title":"Barriers to exercise participation among dialysis patients","volume":"27","author":"Delgado","year":"2012","journal-title":"Nephrol Dial Transplant"},{"issue":"4","key":"10.1053\/j.ajkd.2017.01.051_bib77","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1007\/s11255-007-9265-z","article-title":"Factors influencing exercise participation by older adults requiring chronic hemodialysis: a qualitative study","volume":"39","author":"Kontos","year":"2007","journal-title":"Int Urol Nephrol"},{"issue":"6","key":"10.1053\/j.ajkd.2017.01.051_bib78","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/rnj.98","article-title":"Jordanian dialysis patients' perceived exercise benefits and barriers: a correlation study","volume":"38","author":"Darawad","year":"2013","journal-title":"Rehabil Nurs"},{"issue":"6","key":"10.1053\/j.ajkd.2017.01.051_bib79","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.1093\/ndt\/gfs120","article-title":"The burden of physical inactivity in chronic kidney disease: is there an exit strategy?","volume":"27","author":"Manfredini","year":"2012","journal-title":"Nephrol Dial Transplant"},{"issue":"4","key":"10.1053\/j.ajkd.2017.01.051_bib80","doi-asserted-by":"crossref","first-page":"c330","DOI":"10.1159\/000319593","article-title":"Deficient counseling on physical activity among nephrologists","volume":"116","author":"Delgado","year":"2010","journal-title":"Nephron Clin Pract"},{"issue":"1","key":"10.1053\/j.ajkd.2017.01.051_bib81","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1053\/ajkd.2003.50001","article-title":"Exercise counseling practices among nephrologists caring for patients on dialysis","volume":"41","author":"Johansen","year":"2003","journal-title":"Am J Kidney Dis"},{"issue":"2-3","key":"10.1053\/j.ajkd.2017.01.051_bib82","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1159\/000355793","article-title":"Barriers to physical activity in chronic hemodialysis patients: a single-center pilot study in an Italian dialysis facility","volume":"39","author":"Fiaccadori","year":"2014","journal-title":"Kidney Blood Press Res"},{"key":"10.1053\/j.ajkd.2017.01.051_bib83","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/1748-5908-7-68","article-title":"Patients' perspectives on the implementation of intra-dialytic cycling\u2013a phenomenographic study","volume":"7","author":"Heiwe","year":"2012","journal-title":"Implement Sci"},{"issue":"1","key":"10.1053\/j.ajkd.2017.01.051_bib84","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.semnephrol.2009.10.013","article-title":"Rehabilitation in the renal population: barriers to access","volume":"30","author":"Kutner","year":"2010","journal-title":"Semin Nephrol"},{"issue":"1","key":"10.1053\/j.ajkd.2017.01.051_bib85","first-page":"67","article-title":"Determinants of exercise encouragement practices in hemodialysis staff","volume":"31","author":"Painter","year":"2004","journal-title":"Nephrol Nurs J"},{"issue":"3","key":"10.1053\/j.ajkd.2017.01.051_bib86","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1053\/j.ajkd.2014.01.433","article-title":"Physical function and physical activity assessment and promotion in the hemodialysis clinic: a qualitative study","volume":"64","author":"Painter","year":"2014","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/j.ajkd.2017.01.051_bib87","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1186\/s12882-015-0183-5","article-title":"Factors associated with leisure-time physical activity among patients undergoing hemodialysis","volume":"16","author":"Rosa","year":"2015","journal-title":"BMC Nephrol"},{"issue":"9","key":"10.1053\/j.ajkd.2017.01.051_bib88","doi-asserted-by":"crossref","first-page":"3050","DOI":"10.1093\/ndt\/gfq138","article-title":"Physical exercise among participants in the Dialysis Outcomes and Practice Patterns Study (DOPPS): correlates and associated outcomes","volume":"25","author":"Tentori","year":"2010","journal-title":"Nephrol Dial Transplant"},{"issue":"6","key":"10.1053\/j.ajkd.2017.01.051_bib89","doi-asserted-by":"crossref","first-page":"e0128995","DOI":"10.1371\/journal.pone.0128995","article-title":"Patient and staff perceptions of intradialytic exercise before and after implementation: a qualitative study","volume":"10","author":"Young","year":"2015","journal-title":"PLoS One"},{"issue":"2","key":"10.1053\/j.ajkd.2017.01.051_bib90","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.ijnurstu.2009.05.023","article-title":"Development and psychometric evaluation of the Dialysis patient-perceived Exercise Benefits and Barriers Scale","volume":"47","author":"Zheng","year":"2010","journal-title":"Int J Nurs Stud"},{"issue":"3","key":"10.1053\/j.ajkd.2017.01.051_bib91","first-page":"235","article-title":"Regular physical activity and exercise therapy in end-stage renal disease: how should we move forward?","volume":"23","author":"Bohm","year":"2010","journal-title":"J\u00a0Nephrol"},{"issue":"11","key":"10.1053\/j.ajkd.2017.01.051_bib92","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1093\/ndt\/gfv208","article-title":"Motivations and barriers to exercise in chronic kidney\u00a0disease: a qualitative study","volume":"30","author":"Clarke","year":"2015","journal-title":"Nephrol Dial Transplant"},{"issue":"4 suppl 3","key":"10.1053\/j.ajkd.2017.01.051_bib93","first-page":"S1","article-title":"K\/DOQI clinical practice guidelines for cardiovascular disease in dialysis patients","volume":"45","year":"2005","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/j.ajkd.2017.01.051_bib94","unstructured":"CMS. Decision Memo for Cardiac Rehabilitation (CR) Programs - Chronic Heart Failure (CAG-00437N). 2014. https:\/\/www.cms.gov\/medicare-coverage-database\/details\/nca-decision-memo.aspx?NCAId=270. Accessed December 1, 2016."},{"issue":"6","key":"10.1053\/j.ajkd.2017.01.051_bib95","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1053\/j.ackd.2009.07.010","article-title":"Implementing exercise: what do we know? Where do we go?","volume":"16","author":"Painter","year":"2009","journal-title":"Adv Chronic Kidney Dis"},{"issue":"5","key":"10.1053\/j.ajkd.2017.01.051_bib96","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.jsams.2013.01.005","article-title":"Exercise &\u00a0Sports Science Australia (ESSA) position statement on exercise and chronic kidney disease","volume":"16","author":"Smart","year":"2013","journal-title":"J\u00a0Sci Med Sport"},{"issue":"18","key":"10.1053\/j.ajkd.2017.01.051_bib97","doi-asserted-by":"crossref","first-page":"1902","DOI":"10.1080\/02640414.2015.1017733","article-title":"The BASES expert statement on exercise therapy for people with chronic kidney disease","volume":"33","author":"Koufaki","year":"2015","journal-title":"J\u00a0Sports Sci"},{"key":"10.1053\/j.ajkd.2017.01.051_bib98","series-title":"ACSM's Guidelines for Exercise Testing and Prescription","article-title":"American College of Sports Medicine","author":"Pescatello","year":"2014"},{"issue":"12","key":"10.1053\/j.ajkd.2017.01.051_bib99","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.2165\/11536880-000000000-00000","article-title":"Current best evidence recommendations on measurement and interpretation of physical function in patients with chronic kidney disease","volume":"40","author":"Koufaki","year":"2010","journal-title":"Sports Med"},{"issue":"3","key":"10.1053\/j.ajkd.2017.01.051_bib100","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1249\/01.MSS.0000115224.88514.3A","article-title":"American College of Sports Medicine position stand. Exercise and hypertension","volume":"36","author":"Pescatello","year":"2004","journal-title":"Med Sci Sports Exerc"},{"key":"10.1053\/j.ajkd.2017.01.051_bib101","series-title":"ACSM's Guidelines for Exercise Testing and Prescription","author":"Thompson","year":"2010"},{"issue":"1","key":"10.1053\/j.ajkd.2017.01.051_bib102","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1053\/j.ajkd.2011.10.008","article-title":"Exercise in individuals with CKD","volume":"59","author":"Johansen","year":"2012","journal-title":"Am J Kidney Dis"},{"issue":"1","key":"10.1053\/j.ajkd.2017.01.051_bib103","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1093\/gerona\/glq167","article-title":"Predictive value of the Short Physical Performance Battery following hospitalization in older patients","volume":"66","author":"Volpato","year":"2011","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"issue":"3","key":"10.1053\/j.ajkd.2017.01.051_bib104","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1001\/jamacardio.2016.0316","article-title":"Gait speed and operative mortality in older adults following cardiac surgery","volume":"1","author":"Afilalo","year":"2016","journal-title":"JAMA Cardiol"},{"issue":"1","key":"10.1053\/j.ajkd.2017.01.051_bib105","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/ageing\/26.1.15","article-title":"Comfortable and maximum walking speed of adults aged 20-79 years: reference values and determinants","volume":"26","author":"Bohannon","year":"1997","journal-title":"Age Ageing"},{"issue":"1","key":"10.1053\/j.ajkd.2017.01.051_bib106","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1093\/gerona\/glv126","article-title":"Gait speed predicts incident disability: a pooled analysis","volume":"71","author":"Perera","year":"2016","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"issue":"9","key":"10.1053\/j.ajkd.2017.01.051_bib107","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1093\/ptj\/80.9.896","article-title":"Predicting the probability for falls in community-dwelling older adults using the Timed Up & Go Test","volume":"80","author":"Shumway-Cook","year":"2000","journal-title":"Phys Ther"},{"key":"10.1053\/j.ajkd.2017.01.051_bib108","doi-asserted-by":"crossref","first-page":"25420","DOI":"10.1038\/srep25420","article-title":"Mobility and muscle strength together are more strongly correlated with falls in suburb-dwelling older Chinese","volume":"6","author":"Wang","year":"2016","journal-title":"Sci Rep"},{"issue":"2","key":"10.1053\/j.ajkd.2017.01.051_bib109","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1093\/ptj\/82.2.128","article-title":"Age- and gender-related test performance in community-dwelling elderly people: Six-Minute Walk Test, Berg Balance Scale, Timed Up & Go Test, and gait speeds","volume":"82","author":"Steffen","year":"2002","journal-title":"Phys Ther"},{"issue":"2","key":"10.1053\/j.ajkd.2017.01.051_bib110","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1093\/gerona\/gln022","article-title":"Use of the Short Physical Performance Battery Score to predict loss of ability to walk 400 meters: analysis from the InCHIANTI study","volume":"64","author":"Vasunilashorn","year":"2009","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"issue":"5","key":"10.1053\/j.ajkd.2017.01.051_bib111","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1111\/j.1532-5415.2006.00701.x","article-title":"Meaningful change and responsiveness in common physical performance measures in older adults","volume":"54","author":"Perera","year":"2006","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"2","key":"10.1053\/j.ajkd.2017.01.051_bib112","doi-asserted-by":"crossref","first-page":"M85","DOI":"10.1093\/geronj\/49.2.M85","article-title":"A\u00a0short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission","volume":"49","author":"Guralnik","year":"1994","journal-title":"J\u00a0Gerontol"},{"issue":"1","key":"10.1053\/j.ajkd.2017.01.051_bib113","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1111\/jgs.13195","article-title":"Comparative study of four physical performance measures as predictors of death, incident disability, and falls in unselected older persons: the insufficienza Cardiaca negli Anziani Residenti a Dicomano Study","volume":"63","author":"Minneci","year":"2015","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"10","key":"10.1053\/j.ajkd.2017.01.051_bib114","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1056\/NEJMoa021322","article-title":"The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease","volume":"350","author":"Celli","year":"2004","journal-title":"N\u00a0Engl J Med"},{"key":"10.1053\/j.ajkd.2017.01.051_bib115","doi-asserted-by":"crossref","DOI":"10.1093\/gerona\/glw139","article-title":"A\u00a0comparison of objective physical performance tests and future mortality in the elderly people","author":"Veronese","year":"2016","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"issue":"4","key":"10.1053\/j.ajkd.2017.01.051_bib116","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1164\/rccm.201209-1596OC","article-title":"Six-minute-walk test in chronic obstructive pulmonary disease: minimal clinically important difference for death or hospitalization","volume":"187","author":"Polkey","year":"2013","journal-title":"Am J Respir Crit Care Med"},{"issue":"2-3","key":"10.1053\/j.ajkd.2017.01.051_bib117","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1159\/000355798","article-title":"Physical performance and clinical outcomes in dialysis patients: a secondary analysis of the EXCITE trial","volume":"39","author":"Torino","year":"2014","journal-title":"Kidney Blood Press Res"},{"issue":"2","key":"10.1053\/j.ajkd.2017.01.051_bib118","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1034\/j.1399-3003.1999.14b06.x","article-title":"Six minute walking distance in healthy elderly subjects","volume":"14","author":"Troosters","year":"1999","journal-title":"Eur Respir J"},{"issue":"10","key":"10.1053\/j.ajkd.2017.01.051_bib119","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1093\/gerona\/glu033","article-title":"Are estimates of meaningful decline in mobility performance consistent among clinically important subgroups? (Health ABC study)","volume":"69","author":"Perera","year":"2014","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"issue":"17","key":"10.1053\/j.ajkd.2017.01.051_bib120","doi-asserted-by":"crossref","first-page":"2018","DOI":"10.1001\/jama.295.17.2018","article-title":"Association of long-distance corridor walk performance with mortality, cardiovascular disease, mobility limitation, and disability","volume":"295","author":"Newman","year":"2006","journal-title":"JAMA"},{"issue":"2","key":"10.1053\/j.ajkd.2017.01.051_bib121","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/S0363-5023(84)80146-X","article-title":"Reliability and validity of grip and pinch strength evaluations","volume":"9","author":"Mathiowetz","year":"1984","journal-title":"J\u00a0Hand Surg Am"},{"issue":"1","key":"10.1053\/j.ajkd.2017.01.051_bib122","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1159\/000447703","article-title":"Structured exercise in obese diabetic patients with chronic kidney disease: a randomized controlled trial","volume":"44","author":"Leehey","year":"2016","journal-title":"Am J Nephrol"},{"issue":"4","key":"10.1053\/j.ajkd.2017.01.051_bib123","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1053\/j.ajkd.2014.09.017","article-title":"Exercise training in CKD: efficacy, adherence, and safety","volume":"65","author":"Howden","year":"2015","journal-title":"Am J Kidney Dis"},{"issue":"3","key":"10.1053\/j.ajkd.2017.01.051_bib124","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1053\/j.ajkd.2014.07.015","article-title":"Effect of exercise training on estimated GFR, vascular health, and cardiorespiratory fitness in patients with CKD: a pilot randomized controlled trial","volume":"65","author":"Greenwood","year":"2015","journal-title":"Am J Kidney Dis"},{"issue":"3","key":"10.1053\/j.ajkd.2017.01.051_bib125","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1053\/j.ajkd.2009.03.009","article-title":"Effects of exercise training on noninvasive cardiac measures in patients undergoing long-term hemodialysis: a randomized controlled trial","volume":"54","author":"Kouidi","year":"2009","journal-title":"Am J Kidney Dis"},{"issue":"1","key":"10.1053\/j.ajkd.2017.01.051_bib126","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1177\/0269215508096760","article-title":"Effect of intradialytic exercise training on health-related quality of life indices in haemodialysis patients","volume":"23","author":"Ouzouni","year":"2009","journal-title":"Clin Rehabil"},{"issue":"5","key":"10.1053\/j.ajkd.2017.01.051_bib127","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1080\/08860220701392157","article-title":"The impact of pre-dialytic endurance training on nutritional status and quality of life in stable hemodialysis patients (Sawada study)","volume":"29","author":"Matsumoto","year":"2007","journal-title":"Ren Fail"},{"key":"10.1053\/j.ajkd.2017.01.051_bib128","series-title":"ACSM's Exercise for Older Adults","author":"Chodzko-Zajko","year":"2014"}],"container-title":["American Journal of Kidney Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272638617305449?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272638617305449?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T03:02:55Z","timestamp":1759460575000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0272638617305449"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6]]},"references-count":128,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,6]]}},"alternative-id":["S0272638617305449"],"URL":"https:\/\/doi.org\/10.1053\/j.ajkd.2017.01.051","relation":{},"ISSN":["0272-6386"],"issn-type":[{"value":"0272-6386","type":"print"}],"subject":[],"published":{"date-parts":[[2017,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Exercise and CKD: Skeletal Muscle Dysfunction and Practical Application of Exercise to Prevent and Treat Physical Impairments in CKD","name":"articletitle","label":"Article Title"},{"value":"American Journal of Kidney Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.ajkd.2017.01.051","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 by the National Kidney Foundation, Inc.","name":"copyright","label":"Copyright"}]}}