{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T19:35:22Z","timestamp":1769110522218,"version":"3.49.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100005930","name":"Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005930","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007476","name":"Canadian Diabetes Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007476","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013528","name":"Diabetes Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013528","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009663","name":"University Health Network","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003579","name":"University of Toronto","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003579","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013528","name":"Diabetes Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013528","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Boehringer Ingelheim"},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["T32-DK063687"],"award-info":[{"award-number":["T32-DK063687"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["K23 DK116720-01"],"award-info":[{"award-number":["K23 DK116720-01"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"name":"JDRF"},{"DOI":"10.13039\/100011866","name":"Colorado Clinical and Translational Sciences Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011866","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005622","name":"Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005622","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010174","name":"University of Colorado","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010174","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004191","name":"Novo Nordisk","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004191","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004312","name":"Lilly","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004312","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009947","name":"Merck","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009947","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Boehringer Ingelheim"},{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Boehringer Ingelheim"},{"DOI":"10.13039\/100004312","name":"Lilly","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004312","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Boehringer Ingelheim"},{"DOI":"10.13039\/501100004191","name":"Novo Nordisk","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004191","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001316","name":"Abbott","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001316","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004331","name":"Johnson & Johnson","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004331","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004337","name":"Roche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004337","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004330","name":"GlaxoSmithKline","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004330","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004191","name":"Novo Nordisk","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004191","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004312","name":"Lilly","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004312","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004334","name":"Merck","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004334","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004339","name":"Sanofi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004339","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004312","name":"Lilly","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004312","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ajkd.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Kidney Diseases"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1053\/j.ajkd.2018.12.034","type":"journal-article","created":{"date-parts":[[2019,2,22]],"date-time":"2019-02-22T17:30:35Z","timestamp":1550856635000},"page":"786-796","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["Renal Hemodynamic Function and RAAS Activation Over the Natural History of Type 1 Diabetes"],"prefix":"10.1053","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1805-9994","authenticated-orcid":false,"given":"Yuliya","family":"Lytvyn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petter","family":"Bjornstad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie A.","family":"Lovshin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genevieve","family":"Boulet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed A.","family":"Farooqi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vesta","family":"Lai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josephine","family":"Tse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leslie","family":"Cham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leif E.","family":"Lovblom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alanna","family":"Weisman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hillary A.","family":"Keenan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael H.","family":"Brent","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Narinder","family":"Paul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vera","family":"Bril","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Advani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Etienne","family":"Sochett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce A.","family":"Perkins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David Z.I.","family":"Cherney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"10138","key":"10.1053\/j.ajkd.2018.12.034_bib1","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1016\/S0140-6736(18)31320-5","article-title":"Type 1 diabetes","volume":"391","author":"DiMeglio","year":"2018","journal-title":"Lancet"},{"issue":"14","key":"10.1053\/j.ajkd.2018.12.034_bib2","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1001\/archinternmed.2009.193","volume":"169","author":"Nathan","year":"2009","journal-title":"Arch Intern Med"},{"issue":"11","key":"10.1053\/j.ajkd.2018.12.034_bib3","doi-asserted-by":"crossref","first-page":"2312","DOI":"10.1007\/s00125-010-1860-3","article-title":"In the absence of renal disease, 20 year mortality risk in type 1 diabetes is comparable to that of the general population: a report from the Pittsburgh Epidemiology of Diabetes Complications Study","volume":"53","author":"Orchard","year":"2010","journal-title":"Diabetologia"},{"issue":"1","key":"10.1053\/j.ajkd.2018.12.034_bib4","article-title":"Renin-angiotensin-aldosterone system activation in long-standing type 1 diabetes","volume":"3","author":"Lovshin","year":"2018","journal-title":"JCI\u00a0Insight"},{"issue":"4","key":"10.1053\/j.ajkd.2018.12.034_bib5","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1007\/s00125-009-1268-0","article-title":"Is hyperfiltration associated with the future risk of\u00a0developing diabetic nephropathy? A meta-analysis","volume":"52","author":"Magee","year":"2009","journal-title":"Diabetologia"},{"issue":"1","key":"10.1053\/j.ajkd.2018.12.034_bib6","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1056\/NEJMoa0808400","article-title":"Renal and retinal effects of enalapril and losartan in type 1 diabetes","volume":"361","author":"Mauer","year":"2009","journal-title":"N\u00a0Engl J Med"},{"issue":"10","key":"10.1053\/j.ajkd.2018.12.034_bib7","doi-asserted-by":"crossref","first-page":"686","DOI":"10.2337\/diacare.12.10.686","article-title":"Contribution of diabetes duration before puberty to development of microvascular complications in IDDM subjects","volume":"12","author":"Kostraba","year":"1989","journal-title":"Diabetes Care"},{"issue":"1","key":"10.1053\/j.ajkd.2018.12.034_bib8","doi-asserted-by":"crossref","first-page":"51","DOI":"10.2337\/diab.45.1.51","article-title":"Effect of puberty on markers of glomerular hypertrophy and hypertension in IDDM","volume":"45","author":"Lawson","year":"1996","journal-title":"Diabetes"},{"issue":"18","key":"10.1053\/j.ajkd.2018.12.034_bib9","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1056\/NEJMoa1703518","article-title":"ACE inhibitors and statins in adolescents with type 1 diabetes","volume":"377","author":"Marcovecchio","year":"2017","journal-title":"N\u00a0Engl J Med"},{"issue":"5","key":"10.1053\/j.ajkd.2018.12.034_bib10","doi-asserted-by":"crossref","first-page":"F967","DOI":"10.1152\/ajprenal.00415.2016","article-title":"The Gomez' equations and renal hemodynamic function in kidney disease research","volume":"311","author":"Bjornstad","year":"2016","journal-title":"Am J Physiol Renal Physiol"},{"issue":"6","key":"10.1053\/j.ajkd.2018.12.034_bib11","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1681\/ASN.2005080872","article-title":"Impact of renin angiotensin system modulation on the hyperfiltration state in type 1 diabetes","volume":"17","author":"Sochett","year":"2006","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"7","key":"10.1053\/j.ajkd.2018.12.034_bib12","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.2337\/db17-0168","article-title":"Renal and vascular effects of uric acid lowering in normouricemic patients with uncomplicated type 1 diabetes","volume":"66","author":"Lytvyn","year":"2017","journal-title":"Diabetes"},{"issue":"4","key":"10.1053\/j.ajkd.2018.12.034_bib13","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1111\/j.1523-1755.2005.00588.x","article-title":"Gender differences in renal responses to hyperglycemia and angiotensin-converting enzyme inhibition in diabetes","volume":"68","author":"Cherney","year":"2005","journal-title":"Kidney Int"},{"issue":"7","key":"10.1053\/j.ajkd.2018.12.034_bib14","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.2337\/diabetes.52.7.1806","article-title":"Relationship between diurnal blood pressure, renal hemodynamic function, and the renin-angiotensin system in type 1 diabetes","volume":"52","author":"Miller","year":"2003","journal-title":"Diabetes"},{"issue":"3","key":"10.1053\/j.ajkd.2018.12.034_bib15","doi-asserted-by":"crossref","first-page":"688","DOI":"10.2337\/db07-1230","article-title":"The effect of cyclooxygenase-2 inhibition on renal hemodynamic function in humans with type 1 diabetes","volume":"57","author":"Cherney","year":"2008","journal-title":"Diabetes"},{"issue":"6","key":"10.1053\/j.ajkd.2018.12.034_bib16","doi-asserted-by":"crossref","first-page":"F1336","DOI":"10.1152\/ajprenal.00574.2007","article-title":"Renal hemodynamic effect of cyclooxygenase 2 inhibition in young men and women with uncomplicated type 1 diabetes mellitus","volume":"294","author":"Cherney","year":"2008","journal-title":"Am J Physiol Renal Physiol"},{"issue":"6","key":"10.1053\/j.ajkd.2018.12.034_bib17","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.2337\/dc09-2340","article-title":"Renal hyperfiltration is a determinant of endothelial function responses to cyclooxygenase 2 inhibition in type 1 diabetes","volume":"33","author":"Cherney","year":"2010","journal-title":"Diabetes Care"},{"issue":"7","key":"10.1053\/j.ajkd.2018.12.034_bib18","doi-asserted-by":"crossref","first-page":"R710","DOI":"10.1152\/ajpregu.00286.2012","article-title":"Hyperfiltration and effect of nitric oxide inhibition on renal and endothelial function in humans with uncomplicated type 1 diabetes mellitus","volume":"303","author":"Cherney","year":"2012","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"10","key":"10.1053\/j.ajkd.2018.12.034_bib19","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1172\/JCI102534","article-title":"Evaluation of renal resistances, with special reference to changes in essential hypertension","volume":"30","author":"Gomez","year":"1951","journal-title":"J\u00a0Clin Invest"},{"issue":"12","key":"10.1053\/j.ajkd.2018.12.034_bib20","doi-asserted-by":"crossref","first-page":"2599","DOI":"10.1007\/s00125-014-3396-4","article-title":"Characterisation of glomerular haemodynamic responses to SGLT2 inhibition in\u00a0patients with type 1 diabetes and renal hyperfiltration","volume":"57","author":"Skrtic","year":"2014","journal-title":"Diabetologia"},{"issue":"8","key":"10.1053\/j.ajkd.2018.12.034_bib21","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1111\/dme.13051","article-title":"Plasma uric acid effects on\u00a0glomerular haemodynamic profile of patients with uncomplicated\u00a0type 1 diabetes mellitus","volume":"33","author":"Lytvyn","year":"2016","journal-title":"Diabet Med"},{"issue":"7","key":"10.1053\/j.ajkd.2018.12.034_bib22","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1111\/dme.12717","article-title":"Glomerular haemodynamic profile of patients with type 1 diabetes compared with healthy control subjects","volume":"32","author":"Skrtic","year":"2015","journal-title":"Diabet Med"},{"issue":"3","key":"10.1053\/j.ajkd.2018.12.034_bib23","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1038\/ki.1981.33","article-title":"Glomerular hemodynamics in experimental diabetes mellitus","volume":"19","author":"Hostetter","year":"1981","journal-title":"Kidney Int"},{"issue":"1","key":"10.1053\/j.ajkd.2018.12.034_bib24","doi-asserted-by":"crossref","first-page":"R206","DOI":"10.1152\/ajpregu.00027.2010","article-title":"Age is a determinant of\u00a0acute hemodynamic responses to hyperglycemia and angiotensin II in humans with uncomplicated type 1 diabetes mellitus","volume":"299","author":"Cherney","year":"2010","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"26","key":"10.1053\/j.ajkd.2018.12.034_bib25","doi-asserted-by":"crossref","first-page":"2492","DOI":"10.1056\/NEJMoa1306033","article-title":"Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease","volume":"369","author":"de Zeeuw","year":"2013","journal-title":"N\u00a0Engl J Med"},{"issue":"4","key":"10.1053\/j.ajkd.2018.12.034_bib26","doi-asserted-by":"crossref","first-page":"631","DOI":"10.2215\/CJN.00840207","article-title":"Kidney outcomes in long-term studies of ruboxistaurin for diabetic eye disease","volume":"2","author":"Tuttle","year":"2007","journal-title":"Clin J Am Soc Nephrol"},{"issue":"8","key":"10.1053\/j.ajkd.2018.12.034_bib27","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1681\/ASN.V1081778","article-title":"Impact of hyperglycemia on the renin angiotensin system in early human type 1 diabetes mellitus","volume":"10","author":"Miller","year":"1999","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"10","key":"10.1053\/j.ajkd.2018.12.034_bib28","doi-asserted-by":"crossref","first-page":"2308","DOI":"10.1007\/s00125-013-3000-3","article-title":"The effect of aliskiren on urinary cytokine\/chemokine responses to clamped hyperglycaemia in type 1 diabetes","volume":"56","author":"Cherney","year":"2013","journal-title":"Diabetologia"},{"issue":"4","key":"10.1053\/j.ajkd.2018.12.034_bib29","doi-asserted-by":"crossref","first-page":"280","DOI":"10.2174\/157339908786241151","article-title":"Insights into the regulation of renal hemodynamic function in diabetic mellitus","volume":"4","author":"Cherney","year":"2008","journal-title":"Curr Diabetes Rev"},{"issue":"1","key":"10.1053\/j.ajkd.2018.12.034_bib30","doi-asserted-by":"crossref","first-page":"177","DOI":"10.2337\/dc10-1219","article-title":"The acute effect of clamped hyperglycemia on the urinary excretion of inflammatory cytokines\/chemokines in uncomplicated type 1 diabetes: a pilot study","volume":"34","author":"Cherney","year":"2011","journal-title":"Diabetes Care"},{"issue":"1","key":"10.1053\/j.ajkd.2018.12.034_bib31","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1046\/j.1523-1755.2003.00701.x","article-title":"Glomerular hemodynamics and the renin-angiotensin system in patients with type 1 diabetes mellitus","volume":"63","author":"Hollenberg","year":"2003","journal-title":"Kidney Int"},{"issue":"3","key":"10.1053\/j.ajkd.2018.12.034_bib32","doi-asserted-by":"crossref","first-page":"495","DOI":"10.2337\/diacare.22.3.495","article-title":"Microalbuminuria prevalence varies with age, sex, and puberty in children with type 1 diabetes followed from diagnosis in a longitudinal study. Oxford Regional Prospective Study Group","volume":"22","author":"Schultz","year":"1999","journal-title":"Diabetes Care"},{"issue":"1","key":"10.1053\/j.ajkd.2018.12.034_bib33","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1177\/000992289503400103","article-title":"Microalbuminuria in an adolescent cohort with insulin-dependent diabetes mellitus","volume":"34","author":"Quattrin","year":"1995","journal-title":"Clin Pediatr"},{"issue":"6","key":"10.1053\/j.ajkd.2018.12.034_bib34","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1172\/JCI112521","article-title":"Prevention of diabetic glomerulopathy by pharmacological amelioration of glomerular capillary hypertension","volume":"77","author":"Zatz","year":"1986","journal-title":"J\u00a0Clin Invest"},{"issue":"5","key":"10.1053\/j.ajkd.2018.12.034_bib35","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1161\/CIRCULATIONAHA.113.005081","article-title":"Renal hemodynamic effect of sodium-glucose cotransporter 2 inhibition in\u00a0patients with type 1 diabetes mellitus","volume":"129","author":"Cherney","year":"2014","journal-title":"Circulation"},{"issue":"24","key":"10.1053\/j.ajkd.2018.12.034_bib36","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1056\/NEJMoa1708337","article-title":"Effects of sotagliflozin added to insulin in patients with type 1 diabetes","volume":"377","author":"Garg","year":"2017","journal-title":"N\u00a0Engl J Med"},{"issue":"4","key":"10.1053\/j.ajkd.2018.12.034_bib37","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1056\/NEJMoa1515920","article-title":"Empagliflozin and progression of kidney disease in type 2 diabetes","volume":"375","author":"Wanner","year":"2016","journal-title":"N\u00a0Engl J Med"},{"issue":"7","key":"10.1053\/j.ajkd.2018.12.034_bib38","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1007\/s00125-016-3938-z","article-title":"Acute renal effects of the GLP-1 receptor agonist exenatide in overweight type 2 diabetes patients: a randomised, double-blind, placebo-controlled trial","volume":"59","author":"Tonneijck","year":"2016","journal-title":"Diabetologia"},{"issue":"9","key":"10.1053\/j.ajkd.2018.12.034_bib39","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1056\/NEJMoa1616011","article-title":"Liraglutide and renal outcomes in type 2 diabetes","volume":"377","author":"Mann","year":"2017","journal-title":"N\u00a0Engl J Med"},{"issue":"24","key":"10.1053\/j.ajkd.2018.12.034_bib40","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1056\/NEJMoa1614329","article-title":"Single-nephron glomerular filtration rate in healthy adults","volume":"376","author":"Denic","year":"2017","journal-title":"N\u00a0Engl J Med"},{"issue":"5","key":"10.1053\/j.ajkd.2018.12.034_bib41","doi-asserted-by":"crossref","first-page":"556","DOI":"10.2337\/diab.36.5.556","article-title":"Functional nature of glomerular injury in progressive diabetic glomerulopathy","volume":"36","author":"Tomlanovich","year":"1987","journal-title":"Diabetes"}],"container-title":["American Journal of Kidney Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272638619300447?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272638619300447?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T03:21:09Z","timestamp":1759461669000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0272638619300447"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":41,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["S0272638619300447"],"URL":"https:\/\/doi.org\/10.1053\/j.ajkd.2018.12.034","relation":{},"ISSN":["0272-6386"],"issn-type":[{"value":"0272-6386","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Renal Hemodynamic Function and RAAS Activation Over the Natural History of Type 1 Diabetes","name":"articletitle","label":"Article Title"},{"value":"American Journal of Kidney Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.ajkd.2018.12.034","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 by the National Kidney Foundation, Inc.","name":"copyright","label":"Copyright"}]}}