{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T18:35:39Z","timestamp":1772217339883,"version":"3.50.1"},"reference-count":38,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,19]],"date-time":"2024-05-19T00:00:00Z","timestamp":1716076800000},"content-version":"am","delay-in-days":353,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["ajkd.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Kidney Diseases"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1053\/j.ajkd.2022.11.007","type":"journal-article","created":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T11:27:11Z","timestamp":1672313231000},"page":"647-654","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Associations of Iron Sucrose and Intradialytic Blood Pressure"],"prefix":"10.1053","volume":"81","author":[{"given":"Anika T.","family":"Singh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy E.","family":"Yen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suraj Sarvode","family":"Mothi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sushrut S.","family":"Waikar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Finnian R.","family":"Mc Causland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1053\/j.ajkd.2022.11.007_bib1","doi-asserted-by":"crossref","DOI":"10.1053\/j.ajkd.2021.01.002","article-title":"US Renal Data System 2020 annual data report: epidemiology of kidney disease in the United States","volume":"77","author":"Johansen","year":"2021","journal-title":"Am J Kidney Dis"},{"issue":"3","key":"10.1053\/j.ajkd.2022.11.007_bib2","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1681\/ASN.2014020222","article-title":"Association of mortality risk with various definitions of intradialytic hypotension","volume":"26","author":"Flythe","year":"2015","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"1","key":"10.1053\/j.ajkd.2022.11.007_bib3","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1186\/s12882-019-1662-x","article-title":"Intradialytic hypotension is an important risk factor for critical limb ischemia in patients on hemodialysis","volume":"20","author":"Matsuura","year":"2019","journal-title":"BMC Nephrol"},{"issue":"6","key":"10.1053\/j.ajkd.2022.11.007_bib4","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1111\/sdi.12627","article-title":"A\u00a0brief review of intradialytic hypotension with a focus on survival","volume":"30","author":"Chou","year":"2017","journal-title":"Semin Dialysis"},{"issue":"4","key":"10.1053\/j.ajkd.2022.11.007_bib5","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.ekir.2019.01.001","article-title":"Cumulative exposure to frequent intradialytic hypotension associates with new-onset dementia among elderly hemodialysis patients","volume":"4","author":"Assimon","year":"2019","journal-title":"Kidney Int Rep"},{"issue":"6","key":"10.1053\/j.ajkd.2022.11.007_bib6","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1093\/ckj\/sfaa078","article-title":"An update review of intradialytic hypotension: concept, risk factors, clinical implications and management","volume":"13","author":"Kanbay","year":"2020","journal-title":"Clin Kidney J"},{"issue":"10","key":"10.1053\/j.ajkd.2022.11.007_bib7","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1177\/039139889601901001","article-title":"Rise in blood pressure during hemodialysis-ultrafiltration: a \u201cparadoxical\u201d phenomenon?","volume":"19","author":"Mees","year":"1996","journal-title":"Int J Artif Organs"},{"issue":"3","key":"10.1053\/j.ajkd.2022.11.007_bib8","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1161\/HYPERTENSIONAHA.115.05858","article-title":"Intradialysis hypertension in end-stage renal disease patients","volume":"66","author":"Georgianos","year":"2015","journal-title":"Hypertension"},{"issue":"5","key":"10.1053\/j.ajkd.2022.11.007_bib9","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1038\/sj.ki.5002077","article-title":"Association of intradialytic blood pressure changes with hospitalization and mortality rates in prevalent ESRD patients","volume":"71","author":"Inrig","year":"2007","journal-title":"Kidney Int"},{"issue":"4","key":"10.1053\/j.ajkd.2022.11.007_bib10","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1161\/HYPERTENSIONAHA.121.18058","article-title":"Association of different definitions of intradialytic hypertension with long-term mortality in hemodialysis","volume":"79","author":"Singh","year":"2022","journal-title":"Hypertension"},{"issue":"1-2","key":"10.1053\/j.ajkd.2022.11.007_bib11","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1159\/000503776","article-title":"Intradialytic hypotension: mechanisms and outcome","volume":"49","author":"Sars","year":"2020","journal-title":"Blood Purificat"},{"issue":"1","key":"10.1053\/j.ajkd.2022.11.007_bib12","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2369-5-1","article-title":"Determination of iron sucrose (Venofer) or iron dextran (DexFerrum) removal by hemodialysis: an in-vitro study","volume":"5","author":"Manley","year":"2004","journal-title":"BMC Nephrol"},{"key":"10.1053\/j.ajkd.2022.11.007_bib13","author":"US Food and Drug Administration"},{"issue":"2","key":"10.1053\/j.ajkd.2022.11.007_bib14","first-page":"137","article-title":"Prevention and management of acute reactions to intravenous iron in surgical patients","volume":"17","author":"G\u00f3mez-Ram\u00edrez","year":"2019","journal-title":"Blood Transfus"},{"issue":"suppl 1","key":"10.1053\/j.ajkd.2022.11.007_bib15","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.2215\/CJN.01420406","article-title":"Acute injury with intravenous iron and concerns regarding long-term safety","volume":"1","author":"Bishu","year":"2006","journal-title":"Clin J Am Soc Nephrol"},{"issue":"S1","key":"10.1053\/j.ajkd.2022.11.007_bib16","doi-asserted-by":"crossref","first-page":"S83","DOI":"10.1111\/hdi.12560","article-title":"The available intravenous iron formulations: history, efficacy, and toxicology","volume":"21","author":"Auerbach","year":"2017","journal-title":"Hemodial Int"},{"issue":"1","key":"10.1053\/j.ajkd.2022.11.007_bib17","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.mayocp.2014.10.007","article-title":"The safety of intravenous iron preparations systematic review and meta-analysis","volume":"90","author":"Avni","year":"2015","journal-title":"Mayo Clin Proc"},{"issue":"2","key":"10.1053\/j.ajkd.2022.11.007_bib18","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1053\/ajkd.2001.21293","article-title":"Efficacy and safety of iron sucrose for iron deficiency in patients with dialysis-associated anemia: North American clinical trial","volume":"37","author":"Charytan","year":"2001","journal-title":"Am J Kidney Dis"},{"issue":"5","key":"10.1053\/j.ajkd.2022.11.007_bib19","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1053\/ajkd.2001.28587","article-title":"Intravenous iron sucrose: establishing a safe dose","volume":"38","author":"Chandler","year":"2001","journal-title":"Am J Kidney Dis"},{"issue":"2","key":"10.1053\/j.ajkd.2022.11.007_bib20","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1159\/000486968","article-title":"Positive iron balance in chronic kidney disease: how much is too much and how to tell?","volume":"47","author":"Wish","year":"2018","journal-title":"Am J Nephrol"},{"issue":"2","key":"10.1053\/j.ajkd.2022.11.007_bib21","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1042\/cs0380191","article-title":"Iron absorption in chronic renal disease","volume":"38","author":"Eschbach","year":"1970","journal-title":"Clin Sci"},{"issue":"1","key":"10.1053\/j.ajkd.2022.11.007_bib22","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.kint.2015.10.002","article-title":"Iron management in chronic kidney disease: conclusions from a \u201cKidney Disease: Improving Global Outcomes\u201d (KDIGO) controversies conference","volume":"89","author":"Macdougall","year":"2016","journal-title":"Kidney Int"},{"issue":"10","key":"10.1053\/j.ajkd.2022.11.007_bib23","doi-asserted-by":"crossref","first-page":"2570","DOI":"10.1093\/ndt\/gft062","article-title":"Variation in intravenous iron use internationally and over time: the Dialysis Outcomes and Practice Patterns Study (DOPPS)","volume":"28","author":"Bailie","year":"2013","journal-title":"Nephrol Dial Transplant"},{"issue":"1","key":"10.1053\/j.ajkd.2022.11.007_bib24","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1093\/ndt\/gfg458","article-title":"Anaemia in haemodialysis patients of five European countries: association with morbidity and mortality in the Dialysis Outcomes and Practice Patterns Study (DOPPS)","volume":"19","author":"Locatelli","year":"2004","journal-title":"Nephrol Dial Transplant"},{"issue":"1","key":"10.1053\/j.ajkd.2022.11.007_bib25","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0272-6386(96)90130-4","article-title":"The impact of anemia on cardiomyopathy, morbidity, and mortality in end-stage renal disease","volume":"28","author":"Foley","year":"1996","journal-title":"Am J Kidney Dis"},{"issue":"5","key":"10.1053\/j.ajkd.2022.11.007_bib26","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1056\/NEJMoa1810742","article-title":"Intravenous iron in patients undergoing maintenance hemodialysis","volume":"380","author":"Macdougall","year":"2019","journal-title":"New Engl J Med"},{"issue":"19","key":"10.1053\/j.ajkd.2022.11.007_bib27","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1001\/jama.2015.15572","article-title":"Comparative risk of anaphylactic reactions associated with intravenous iron products","volume":"314","author":"Wang","year":"2015","journal-title":"JAMA"},{"issue":"7","key":"10.1053\/j.ajkd.2022.11.007_bib28","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1093\/ndt\/gfh820","article-title":"Hypersensitivity reactions and deaths associated with intravenous iron preparations","volume":"20","author":"Bailie","year":"2005","journal-title":"Nephrol Dial Transplant"},{"issue":"6","key":"10.1053\/j.ajkd.2022.11.007_bib29","doi-asserted-by":"crossref","first-page":"2846","DOI":"10.1111\/j.1523-1755.2005.00758.x","article-title":"States Iron Sucrose (Venofer) Clinical Trials Group. A randomized, controlled trial comparing intravenous iron sucrose to oral iron in anemic patients with nondialysis-dependent CKD","volume":"68","author":"Wyck","year":"2005","journal-title":"Kidney Int"},{"issue":"3","key":"10.1053\/j.ajkd.2022.11.007_bib30","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1111\/j.1523-1755.2004.00872.x","article-title":"Iron sucrose in hemodialysis patients: safety of replacement and maintenance regimens","volume":"66","author":"Aronoff","year":"2004","journal-title":"Kidney Int"},{"issue":"1","key":"10.1053\/j.ajkd.2022.11.007_bib31","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1053\/ajkd.2000.8276","article-title":"Safety and efficacy of iron sucrose in patients sensitive to iron dextran: North American clinical trial","volume":"36","author":"Van Wyck","year":"2000","journal-title":"Am J Kidney Dis"},{"issue":"4","key":"10.1053\/j.ajkd.2022.11.007_bib32","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1053\/j.ajkd.2012.10.019","article-title":"Comparison of the safety and efficacy of 3 iron sucrose iron maintenance regimens in children, adolescents, and young adults with CKD: a randomized controlled trial","volume":"61","author":"Goldstein","year":"2013","journal-title":"Am J Kidney Dis"},{"issue":"6","key":"10.1053\/j.ajkd.2022.11.007_bib33","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1111\/sdi.12629","article-title":"Osmolality and blood pressure stability during hemodialysis","volume":"30","author":"Singh","year":"2017","journal-title":"Semin Dial"},{"issue":"4","key":"10.1053\/j.ajkd.2022.11.007_bib34","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1007\/s10534-011-9409-6","article-title":"Non-transferrin bound iron, cytokine activation and intracellular reactive oxygen species generation in hemodialysis patients receiving intravenous iron dextran or iron sucrose","volume":"24","author":"Pai","year":"2011","journal-title":"Biometals"},{"issue":"1","key":"10.1053\/j.ajkd.2022.11.007_bib35","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1038\/ki.1996.25","article-title":"Effect of reactive oxygen species on endothelin-1 production by human mesangial cells","volume":"49","author":"Hughes","year":"1996","journal-title":"Kidney Int"},{"issue":"1","key":"10.1053\/j.ajkd.2022.11.007_bib36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00277-001-0409-4","article-title":"Iron deficiency anemia increases nitric oxide production in healthy adolescents","volume":"81","author":"Choi","year":"2002","journal-title":"Ann Hematol"},{"issue":"8","key":"10.1053\/j.ajkd.2022.11.007_bib37","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/j.amjmed.2019.02.018","article-title":"Iron supplementation improves cardiovascular outcomes in patients with heart failure","volume":"132","author":"Zhou","year":"2019","journal-title":"Am J Med"},{"issue":"3","key":"10.1053\/j.ajkd.2022.11.007_bib38","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.ejpb.2011.03.016","article-title":"A\u00a0comparative study of the physicochemical properties of iron isomaltoside 1000 (Monofer), a new intravenous iron preparation and its clinical implications","volume":"78","author":"Jahn","year":"2011","journal-title":"Eur J Pharm Biopharm"}],"container-title":["American Journal of Kidney Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272638622010915?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272638622010915?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T03:48:08Z","timestamp":1759463288000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0272638622010915"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":38,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["S0272638622010915"],"URL":"https:\/\/doi.org\/10.1053\/j.ajkd.2022.11.007","relation":{},"ISSN":["0272-6386"],"issn-type":[{"value":"0272-6386","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Associations of Iron Sucrose and Intradialytic Blood Pressure","name":"articletitle","label":"Article Title"},{"value":"American Journal of Kidney Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.ajkd.2022.11.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 by the National Kidney Foundation, Inc.","name":"copyright","label":"Copyright"}]}}