{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T14:34:09Z","timestamp":1790865249674,"version":"4.1.0"},"reference-count":52,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2006,7,1]],"date-time":"2006-07-01T00:00:00Z","timestamp":1151712000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,7,1]],"date-time":"2006-07-01T00:00:00Z","timestamp":1151712000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100008732","name":"Uehara Memorial Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008732","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007449","name":"Takeda Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007449","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","gastrojournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastroenterology"],"published-print":{"date-parts":[[2006,7]]},"DOI":"10.1053\/j.gastro.2006.04.025","type":"journal-article","created":{"date-parts":[[2006,7,9]],"date-time":"2006-07-09T07:06:53Z","timestamp":1152428813000},"page":"179-193","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":145,"title":["Deletion of the SOCS3 Gene in Liver Parenchymal Cells Promotes Hepatitis\u2013Induced Hepatocarcinogenesis"],"prefix":"10.1053","volume":"131","author":[{"given":"Hisanobu","family":"Ogata","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takatoshi","family":"Chinen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromi","family":"Takaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahito","family":"Sanada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasumasa","family":"Minoda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiko","family":"Koga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giichi","family":"Takaesu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiko","family":"Maehara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuo","family":"Iida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiko","family":"Yoshimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/j.gastro.2006.04.025_bib1","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0092-8674(00)81959-5","article-title":"Stat3 as an oncogene","volume":"98","author":"Bromberg","year":"1999","journal-title":"Cell"},{"key":"10.1053\/j.gastro.2006.04.025_bib2","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1007\/BF03403538","article-title":"STAT signaling in the pathogenesis and treatment of cancer","volume":"5","author":"Frank","year":"1999","journal-title":"Mol Med"},{"key":"10.1053\/j.gastro.2006.04.025_bib3","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1128\/MCB.18.5.2545","article-title":"Stat3 activation by Src induces specific gene regulation and is required for cell transformation","volume":"18","author":"Turkson","year":"1998","journal-title":"Mol Cell Biol"},{"key":"10.1053\/j.gastro.2006.04.025_bib4","doi-asserted-by":"crossref","first-page":"2553","DOI":"10.1128\/MCB.18.5.2553","article-title":"Stat3 activation is required for cellular transformation by v-src","volume":"18","author":"Bromberg","year":"1998","journal-title":"Mol Cell Biol"},{"key":"10.1053\/j.gastro.2006.04.025_bib5","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S1074-7613(00)80501-4","article-title":"Two signals are necessary for cell proliferation induced by a cytokine receptor gp130","volume":"5","author":"Fukada","year":"1996","journal-title":"Immunity"},{"key":"10.1053\/j.gastro.2006.04.025_bib6","doi-asserted-by":"crossref","first-page":"3945","DOI":"10.1002\/(SICI)1521-4141(199912)29:12<3945::AID-IMMU3945>3.0.CO;2-O","article-title":"IL-6 up-regulates mcl-1 in human myeloma cells through JAK\/STAT rather than ras\/MAP kinase pathway","volume":"29","author":"Puthier","year":"1999","journal-title":"Eur J Immunol"},{"key":"10.1053\/j.gastro.2006.04.025_bib7","doi-asserted-by":"crossref","first-page":"4654","DOI":"10.1038\/sj.onc.1202835","article-title":"Inhibition of pp60c-Src reduces Bcl-XL expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors","volume":"18","author":"Karni","year":"1999","journal-title":"Oncogene"},{"key":"10.1053\/j.gastro.2006.04.025_bib8","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/S1097-2765(01)00199-X","article-title":"Cooperation between STAT3 and c-jun suppresses Fas transcription","volume":"7","author":"Ivanov","year":"2001","journal-title":"Mol Cell"},{"key":"10.1053\/j.gastro.2006.04.025_bib9","doi-asserted-by":"crossref","first-page":"5419","DOI":"10.1038\/sj.onc.1203947","article-title":"Induction of p21WAF1\/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts","volume":"19","author":"Sinibaldi","year":"2000","journal-title":"Oncogene"},{"key":"10.1053\/j.gastro.2006.04.025_bib10","first-page":"547","article-title":"IL-6-inducible complexes on an IL-6 response element of the junB promoter contain Stat3 and 36 kDa CRE-like site binding protein(s)","volume":"12","author":"Kojima","year":"1996","journal-title":"Oncogene"},{"key":"10.1053\/j.gastro.2006.04.025_bib11","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1084\/jem.189.1.63","article-title":"STAT3 is required for the gp130-mediated full activation of the c-myc gene","volume":"189","author":"Kiuchi","year":"1999","journal-title":"J Exp Med"},{"key":"10.1053\/j.gastro.2006.04.025_bib12","doi-asserted-by":"crossref","first-page":"7319","DOI":"10.1073\/pnas.131568898","article-title":"Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis","volume":"98","author":"Bowman","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1053\/j.gastro.2006.04.025_bib13","doi-asserted-by":"crossref","first-page":"15794","DOI":"10.1074\/jbc.M213073200","article-title":"Independent and cooperative activation of chromosomal c-fos promoter by STAT3","volume":"278","author":"Yang","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1053\/j.gastro.2006.04.025_bib14","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1046\/j.1365-2443.1999.00263.x","article-title":"Cytokine-inducible SH2 protein-3 (CIS3\/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as the SH2 domain","volume":"4","author":"Sasaki","year":"1999","journal-title":"Genes Cells"},{"key":"10.1053\/j.gastro.2006.04.025_bib15","doi-asserted-by":"crossref","first-page":"29338","DOI":"10.1074\/jbc.M003456200","article-title":"CIS3\/SOCS-3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2","volume":"275","author":"Sasaki","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1053\/j.gastro.2006.04.025_bib16","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/S1074-7613(02)00446-6","article-title":"SOCS1\/JAB is a negative regulator of LPS-induced macrophage activation","volume":"17","author":"Kinjyo","year":"2002","journal-title":"Immunity"},{"key":"10.1053\/j.gastro.2006.04.025_bib17","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1038\/ni931","article-title":"SOCS3 negatively regulates IL-6 signaling in vivo","volume":"4","author":"Croker","year":"2003","journal-title":"Nat Immunol"},{"key":"10.1053\/j.gastro.2006.04.025_bib18","doi-asserted-by":"crossref","first-page":"6905","DOI":"10.1074\/jbc.C300496200","article-title":"SOCS3 is a physiological negative regulator for granulopoiesis and granulocyte colony-stimulating factor receptor signaling","volume":"279","author":"Kimura","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1053\/j.gastro.2006.04.025_bib19","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1038\/nm1071","article-title":"Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity","volume":"10","author":"Mori","year":"2004","journal-title":"Nat Med"},{"key":"10.1053\/j.gastro.2006.04.025_bib20","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1038\/ni938","article-title":"IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages","volume":"4","author":"Yasukawa","year":"2003","journal-title":"Nat Immunol"},{"key":"10.1053\/j.gastro.2006.04.025_bib21","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S1074-7613(04)00022-6","article-title":"SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis","volume":"20","author":"Croker","year":"2004","journal-title":"Immunity"},{"key":"10.1053\/j.gastro.2006.04.025_bib22","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1038\/nm1072","article-title":"Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3","volume":"10","author":"Howard","year":"2004","journal-title":"Nat Med"},{"key":"10.1053\/j.gastro.2006.04.025_bib23","doi-asserted-by":"crossref","first-page":"12848","DOI":"10.1074\/jbc.275.17.12848","article-title":"SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130","volume":"275","author":"Schmitz","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1053\/j.gastro.2006.04.025_bib24","doi-asserted-by":"crossref","first-page":"6493","DOI":"10.1073\/pnas.100135197","article-title":"Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130","volume":"97","author":"Nicholson","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1053\/j.gastro.2006.04.025_bib25","doi-asserted-by":"crossref","first-page":"9324","DOI":"10.1073\/pnas.161271798","article-title":"Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3","volume":"98","author":"Roberts","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1053\/j.gastro.2006.04.025_bib26","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1093\/emboj\/cdg057","article-title":"SOCS3","volume":"22","author":"Takahashi","year":"2003","journal-title":"EMBO J"},{"key":"10.1053\/j.gastro.2006.04.025_bib27","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1038\/nm1072","article-title":"Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3","volume":"10","author":"Howard","year":"2004","journal-title":"Nat Med"},{"key":"10.1053\/j.gastro.2006.04.025_bib28","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S1074-7613(04)00022-6","article-title":"SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis","volume":"20","author":"Croker","year":"2004","journal-title":"Immunity"},{"key":"10.1053\/j.gastro.2006.04.025_bib29","doi-asserted-by":"crossref","first-page":"16333","DOI":"10.1073\/pnas.0508023102","article-title":"Genetic reduction of embryonic leukemia-inhibitory factor production rescues placentation in SOCS3-null embryos but does not prevent inflammatory disease","volume":"102","author":"Robb","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1053\/j.gastro.2006.04.025_bib30","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1002\/(SICI)1526-968X(200002)26:2<149::AID-GENE16>3.0.CO;2-V","article-title":"DNA excision in liver by an albumin-Cre transgene occurs progressively with age","volume":"26","author":"Postic","year":"2000","journal-title":"Genesis"},{"key":"10.1053\/j.gastro.2006.04.025_bib31","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1084\/jem.20031675","article-title":"SOCS1 is a suppressor of liver fibrosis and hepatitis-induced carcinogenesis","volume":"199","author":"Yoshida","year":"2004","journal-title":"J Exp Med"},{"key":"10.1053\/j.gastro.2006.04.025_bib32","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1600-0676.1987.tb00310.x","article-title":"Relationship of histologic grade of hepatocellular carcinoma (HCC) to tumor size, and demonstration of tumor cells of multiple different grades in single small HCC","volume":"7","author":"Kenmochi","year":"1987","journal-title":"Liver"},{"key":"10.1053\/j.gastro.2006.04.025_bib33","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1172\/JCI118055","article-title":"Cell-specific expression of transforming growth factor-beta in rat liver","volume":"96","author":"Bissell","year":"1995","journal-title":"J Clin Invest"},{"key":"10.1053\/j.gastro.2006.04.025_bib34","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1084\/jem.20012127","article-title":"Activation of STAT3 by the hepatitis C virus core protein leads to cellular transformation","volume":"196","author":"Yoshida","year":"2002","journal-title":"J Exp Med"},{"key":"10.1053\/j.gastro.2006.04.025_bib35","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1002\/hep.20158","article-title":"Electric foot shock stress-induced exacerbation of alpha-galactosylceramide-triggered apoptosis in mouse liver","volume":"39","author":"Chida","year":"2004","journal-title":"Hepatology"},{"key":"10.1053\/j.gastro.2006.04.025_bib36","doi-asserted-by":"crossref","first-page":"6578","DOI":"10.4049\/jimmunol.166.11.6578","article-title":"Mechanisms of the antimetastatic effect in the liver and of the hepatocyte injury induced by alpha-galactosylceramide in mice","volume":"166","author":"Nakagawa","year":"2001","journal-title":"J Immunol"},{"key":"10.1053\/j.gastro.2006.04.025_bib37","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1038\/labinvest.3700257","article-title":"Interferon-gamma-mediated hepatocarcinogenesis in mice treated with diethylnitrosamine","volume":"85","author":"Matsuda","year":"2005","journal-title":"Lab Invest"},{"key":"10.1053\/j.gastro.2006.04.025_bib38","doi-asserted-by":"crossref","first-page":"2000","DOI":"10.1038\/sj.onc.1205260","article-title":"Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis","volume":"21","author":"Niu","year":"2002","journal-title":"Oncogene"},{"key":"10.1053\/j.gastro.2006.04.025_bib39","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/S0016-5085(00)70223-X","article-title":"NO-aspirin protects from T cell-mediated liver injury by inhibiting caspase-dependent processing of Th1-like cytokines","volume":"118","author":"Fiorucci","year":"2000","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2006.04.025_bib40","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1172\/JCI115836","article-title":"A T cell-dependent experimental liver injury in mice inducible by concanavalin A","volume":"90","author":"Tiegs","year":"1992","journal-title":"J Clin Invest"},{"key":"10.1053\/j.gastro.2006.04.025_bib41","doi-asserted-by":"crossref","first-page":"5498","DOI":"10.1073\/pnas.040566697","article-title":"Critical contribution of liver natural killer T cells to a murine model of hepatitis","volume":"97","author":"Takeda","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1053\/j.gastro.2006.04.025_bib42","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1172\/JCI0215841","article-title":"Opposing roles of STAT1 and STAT3 in T cell-mediated hepatitis","volume":"110","author":"Hong","year":"2002","journal-title":"J Clin Invest"},{"key":"10.1053\/j.gastro.2006.04.025_bib43","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1002\/hep.510310123","article-title":"Increased toxin-induced liver injury and fibrosis in interleukin-6-deficient mice","volume":"31","author":"Kovalovich","year":"2000","journal-title":"Hepatology"},{"key":"10.1053\/j.gastro.2006.04.025_bib44","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1038\/ncponc0195","article-title":"Mechanisms of disease","volume":"2","author":"Haura","year":"2005","journal-title":"Nat Clin Pract Oncol"},{"key":"10.1053\/j.gastro.2006.04.025_bib45","doi-asserted-by":"crossref","first-page":"2502","DOI":"10.1016\/j.ejca.2005.08.016","article-title":"The role of IL-6 and STAT3 in inflammation and cancer","volume":"41","author":"Hodge","year":"2005","journal-title":"Eur J Cancer"},{"key":"10.1053\/j.gastro.2006.04.025_bib46","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1038\/nm1282","article-title":"Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling","volume":"11","author":"Jenkins","year":"2005","journal-title":"Nat Med"},{"key":"10.1053\/j.gastro.2006.04.025_bib47","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1038\/nm976","article-title":"Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells","volume":"10","author":"Wang","year":"2004","journal-title":"Nat Med"},{"key":"10.1053\/j.gastro.2006.04.025_bib48","doi-asserted-by":"crossref","first-page":"5054","DOI":"10.1158\/0008-5472.CAN-04-4281","article-title":"Identification of a genetic signature of activated signal transducer and activator of transcription 3 in human tumors","volume":"65","author":"Alvarez","year":"2005","journal-title":"Cancer Res"},{"key":"10.1053\/j.gastro.2006.04.025_bib49","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/ng0501-29","article-title":"SOCS-1, a negative regulator of the JAK\/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity","volume":"28","author":"Yoshikawa","year":"2001","journal-title":"Nat Genet"},{"key":"10.1053\/j.gastro.2006.04.025_bib50","doi-asserted-by":"crossref","first-page":"14133","DOI":"10.1073\/pnas.2232790100","article-title":"SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer","volume":"100","author":"He","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1053\/j.gastro.2006.04.025_bib51","doi-asserted-by":"crossref","first-page":"6406","DOI":"10.1038\/sj.onc.1208788","article-title":"Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK\/STAT and FAK signalings in human hepatocellular carcinoma","volume":"24","author":"Niwa","year":"2005","journal-title":"Oncogene"},{"key":"10.1053\/j.gastro.2006.04.025_bib52","doi-asserted-by":"crossref","first-page":"6699","DOI":"10.1038\/sj.onc.1208818","article-title":"SOCS-3 is frequently methylated in head and neck squamous cell carcinoma and its precursor lesions and causes growth inhibition","volume":"24","author":"Weber","year":"2005","journal-title":"Oncogene"}],"container-title":["Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508506008146?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508506008146?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T09:36:03Z","timestamp":1762162563000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016508506008146"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,7]]},"references-count":52,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,7]]}},"alternative-id":["S0016508506008146"],"URL":"https:\/\/doi.org\/10.1053\/j.gastro.2006.04.025","relation":{},"ISSN":["0016-5085"],"issn-type":[{"value":"0016-5085","type":"print"}],"subject":[],"published":{"date-parts":[[2006,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Deletion of the SOCS3 Gene in Liver Parenchymal Cells Promotes Hepatitis\u2013Induced Hepatocarcinogenesis","name":"articletitle","label":"Article Title"},{"value":"Gastroenterology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.gastro.2006.04.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1053\/j.gastro.2006.05.030","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 American Gastroenterological Association Institute. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}