{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T13:56:14Z","timestamp":1790517374113,"version":"4.1.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2010,4,1]],"date-time":"2010-04-01T00:00:00Z","timestamp":1270080000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,4,1]],"date-time":"2010-04-01T00:00:00Z","timestamp":1270080000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","gastrojournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastroenterology"],"published-print":{"date-parts":[[2010,4]]},"DOI":"10.1053\/j.gastro.2009.12.057","type":"journal-article","created":{"date-parts":[[2010,1,15]],"date-time":"2010-01-15T01:09:57Z","timestamp":1263517797000},"page":"1302-1311","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":112,"title":["Epidemiology of Functional Dyspepsia and Subgroups in the Italian General Population: An Endoscopic Study"],"prefix":"10.1053","volume":"138","author":[{"given":"Rocco Maurizio","family":"Zagari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graham Richard","family":"Law","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Fuccio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Cennamo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark S.","family":"Gilthorpe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Forman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franco","family":"Bazzoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/j.gastro.2009.12.057_bib1","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1053\/j.gastro.2005.09.020","article-title":"American Gastroenterological Association technical review on the evaluation of dyspepsia","volume":"129","author":"Talley","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2009.12.057_bib2","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1053\/j.gastro.2005.11.059","article-title":"Functional gastroduodenal disorders","volume":"130","author":"Tack","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2009.12.057_bib3","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1001\/jama.2007.51-a","article-title":"A 32-year-old woman with chronic abdominal pain","volume":"299","author":"Lacy","year":"2008","journal-title":"JAMA"},{"key":"10.1053\/j.gastro.2009.12.057_bib4","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1046\/j.1365-2036.2003.01706.x","article-title":"Health-related quality of life in functional dyspepsia","volume":"18","author":"El-Serag","year":"2003","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1053\/j.gastro.2009.12.057_bib5","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1136\/gut.50.suppl_4.iv10","article-title":"Clinical and economic consequences of dyspepsia in the community","volume":"50","author":"Moayyedi","year":"2002","journal-title":"Gut"},{"key":"10.1053\/j.gastro.2009.12.057_bib6","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1111\/j.1365-2036.2004.01897.x","article-title":"Systematic review: the prevalence and clinical course of functional dyspepsia","volume":"19","author":"El-Serag","year":"2004","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1053\/j.gastro.2009.12.057_bib7","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1007\/BF01303162","article-title":"U.S. Householder survey of functional gastrointestinal disorders","volume":"38","author":"Drossman","year":"1993","journal-title":"Dig Dis Sci"},{"key":"10.1053\/j.gastro.2009.12.057_bib8","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1023\/A:1013208713670","article-title":"Functional gastrointestinal disorders in Canada: first population-based survey using Rome II criteria with suggestions for improving the questionnaire","volume":"47","author":"Thompson","year":"2002","journal-title":"Dig Dis Sci"},{"key":"10.1053\/j.gastro.2009.12.057_bib9","doi-asserted-by":"crossref","first-page":"2290","DOI":"10.1111\/j.1572-0241.2002.05783.x","article-title":"Epidemiology and health care seeking in the functional GI disorders: a population-based study","volume":"97","author":"Kolosky","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2009.12.057_bib10","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/j.1445-5994.2006.01006.x","article-title":"Epidemiology of the functional gastrointestinal disorders diagnosed according to the Rome II criteria: an Australian population-based study","volume":"36","author":"Boyce","year":"2006","journal-title":"Intern Med J"},{"key":"10.1053\/j.gastro.2009.12.057_bib11","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1111\/j.1365-2982.2009.01262.x","article-title":"Dyspeptic symptoms in the general population: a factor and cluster analysis of symptoms groupings","volume":"21","author":"Piessevaux","year":"2009","journal-title":"Neurogastroenterology"},{"key":"10.1053\/j.gastro.2009.12.057_bib12","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1136\/gut.38.6.822","article-title":"Non-ulcer dyspepsia and peptic ulcer: the distribution in a population and their relation to risk factors","volume":"38","author":"Bernersen","year":"1996","journal-title":"Gut"},{"key":"10.1053\/j.gastro.2009.12.057_bib13","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1053\/j.gastro.2009.03.039","article-title":"Anxiety is associated with uninvestigated and functional dyspepsia (Rome III criteria) in a Swedish population-based study","volume":"137","author":"Aro","year":"2009","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2009.12.057_bib14","doi-asserted-by":"crossref","first-page":"2210","DOI":"10.1111\/j.1572-0241.2004.40052.x","article-title":"The prevalence and risk factors of functional dyspepsia in a multiethnic population in the United States","volume":"99","author":"Shaib","year":"2004","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2009.12.057_bib15","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1080\/00365520510012190","article-title":"Prevalence and health\/social impacts of functional dyspepsia in Taiwan: a study based on the Rome Criteria Questionnaire Survey assisted by endoscopy exclusion among a physical check-up population","volume":"40","author":"Lu","year":"2005","journal-title":"Scand J Gastroenterol"},{"key":"10.1053\/j.gastro.2009.12.057_bib16","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1111\/j.1572-0241.2007.01381.x","article-title":"Do distinct dyspepsia subgroups exist in the community?","volume":"102","author":"Choung","year":"2007","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2009.12.057_bib17","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s00535-008-2167-8","article-title":"Functional dyspepsia: past, present and future","volume":"43","author":"Geeraerts","year":"2008","journal-title":"J Gastroenterol"},{"key":"10.1053\/j.gastro.2009.12.057_bib18","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1002\/hep.510300401","article-title":"Clinical manifestations of gallstone disease: evidence from the multicenter Italian study on cholelithiasis (MICOL)","volume":"30","author":"Festi","year":"1999","journal-title":"Hepatology"},{"key":"10.1053\/j.gastro.2009.12.057_bib19","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1136\/gut.2007.145177","article-title":"Gastroesophageal reflux symptoms, oesophagitis and Barrett's oesophagus in the general population: the Loiano-Monghidoro Study","volume":"57","author":"Zagari","year":"2008","journal-title":"Gut"},{"key":"10.1053\/j.gastro.2009.12.057_bib20","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1046\/j.1365-2036.2001.00972.x","article-title":"The Loiano-Monghidoro population-based study of Helicobacter pylori infection: prevalence by 13C-urea breath test and associated factors","volume":"15","author":"Bazzoli","year":"2001","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1053\/j.gastro.2009.12.057_bib21","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1016\/j.dld.2004.07.010","article-title":"Measuring dyspepsia: a new severity index validated in Bologna","volume":"36","author":"De Luca","year":"2004","journal-title":"Dig Liver Dis"},{"issue":"Suppl 2","key":"10.1053\/j.gastro.2009.12.057_bib22","first-page":"37","article-title":"Functional gastroduodenal disorders","volume":"45","author":"Talley","year":"1999","journal-title":"Gut"},{"key":"10.1053\/j.gastro.2009.12.057_bib23","doi-asserted-by":"crossref","first-page":"2324","DOI":"10.1111\/j.1572-0241.2005.00225.x","article-title":"Guidelines for the management of dyspepsia","volume":"100","author":"Talley","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2009.12.057_bib24","first-page":"75","article-title":"Functional bowel disease and functional abdominal pain","volume":"5","author":"Thompson","year":"1992","journal-title":"Gastroenterol Int"},{"key":"10.1053\/j.gastro.2009.12.057_bib25","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1016\/0016-5085(93)90142-Y","article-title":"Lack of discriminant value of dyspepsia subgroups in patients referred for upper endoscopy","volume":"105","author":"Talley","year":"1993","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2009.12.057_bib26","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1097\/00000478-199610000-00001","article-title":"Classification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis, Houston 1994","volume":"20","author":"Dixon","year":"1996","journal-title":"Am J Surg Pathol"},{"key":"10.1053\/j.gastro.2009.12.057_bib28","article-title":"Dyspeptic symptoms and endoscopic findings in the community: the Loiano-Monghidoro study","author":"Zagari","year":"2009","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2009.12.057_bib29","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.1111\/j.1572-0241.1999.01427.x","article-title":"Prevalence and impact of upper gastrointestinal symptoms in the Canadian population: findings from the DIGEST Study","volume":"94","author":"Tougas","year":"1999","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2009.12.057_bib30","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1080\/00365520510024070","article-title":"Risk factors for dyspepsia in a general population: non steroidal anti-inflammatory drugs, cigarette smoking and unemployment are more important than Helicobacter pylori infection","volume":"41","author":"Wildner-Christensen","year":"2006","journal-title":"Scand J Gastroenterol"},{"key":"10.1053\/j.gastro.2009.12.057_bib31","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1006\/jado.1997.0086","article-title":"Nervous and depressive symptoms in a longitudinal study of youth unemployement","volume":"20","author":"Hammarstrom","year":"1997","journal-title":"J Adolesc"},{"key":"10.1053\/j.gastro.2009.12.057_bib32","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/S0277-9536(02)00109-0","article-title":"Psychological distress during unemployement and beyond: social support and material deprivation among youth in six northern European countries","volume":"56","author":"Bjarnason","year":"2003","journal-title":"Soc Sci Med"},{"key":"10.1053\/j.gastro.2009.12.057_bib33","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1177\/070674370605101007","article-title":"Twelve-month psychiatric disorder among single and married mothers: the role of marital status","volume":"51","author":"Cairney","year":"2006","journal-title":"Can J Psychiatry"},{"key":"10.1053\/j.gastro.2009.12.057_bib34","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1097\/PSY.0b013e31816f857b","article-title":"Marital status and twins' health and behaviour: an analysis of middle-aged Danish twins","volume":"70","author":"Osler","year":"2008","journal-title":"Psychosom Med"},{"key":"10.1053\/j.gastro.2009.12.057_bib35","doi-asserted-by":"crossref","first-page":"524","DOI":"10.3109\/00365529509089784","article-title":"Life event and stress in patients with functional dyspepsia compared with patients with duodenal ulcer and healthy controls","volume":"30","author":"Tangen Haug","year":"1995","journal-title":"Scand J Gastroenterol"},{"key":"10.1053\/j.gastro.2009.12.057_bib36","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1111\/j.1572-0241.2001.03789.x","article-title":"Predictors of health care seeking for irritable bowel syndrome and non-ulcer dyspepsia: a critical review of the literature on symptom and psychosocial factors","volume":"96","author":"Kolosky","year":"2001","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2009.12.057_bib37","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1111\/j.1572-0241.2004.04043.x","article-title":"Psychosocial factors are linked to functional gastrointestinal disorders: a population based nested case control study","volume":"99","author":"Locke","year":"2004","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2009.12.057_bib38","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1053\/j.gastro.2005.11.057","article-title":"Psychosocial aspects of the functional gastrointestinal disorders","volume":"130","author":"Levy","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2009.12.057_bib39","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1136\/bmj.b1314","article-title":"How will the financial crisis affect health?","volume":"338","author":"Marmot","year":"2009","journal-title":"BMJ"},{"key":"10.1053\/j.gastro.2009.12.057_bib40","doi-asserted-by":"crossref","first-page":"S359","DOI":"10.1093\/geronb\/63.6.S359","article-title":"Differences over time in the relationship between paternship disruptions and support in early old age in Britain","volume":"63","author":"Glaser","year":"2008","journal-title":"J Gerontol B Psychol Sci Soc Sci"},{"key":"10.1053\/j.gastro.2009.12.057_bib41","first-page":"524","article-title":"Smoking, alcohol, and nonsteroidal anti-inflammatory drugs in outpatients with functional dyspepsia and among dyspepsia subgroups","volume":"89","author":"Talley","year":"1993","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2009.12.057_bib42","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1111\/j.1572-0241.2000.2126_1.x","article-title":"The proportion of upper gastrointestinal symptoms in the community associated with Helicobacter pylori, lifestyle factors, and nonsteroidal anti-inflammatory drugs","volume":"95","author":"Moayyedi","year":"2000","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2009.12.057_bib43","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1080\/00365520510012271","article-title":"Prevalence and impact of upper and lower gastrointestinal symptoms in the Greek urban general population","volume":"40","author":"Papatheodoridis","year":"2005","journal-title":"Scand J Gastroenterol"},{"key":"10.1053\/j.gastro.2009.12.057_bib44","first-page":"1025","article-title":"Peptic ulcer disease in the general adult population","volume":"63","author":"Aro","year":"2005","journal-title":"Am J Epidemiol"},{"key":"10.1053\/j.gastro.2009.12.057_bib45","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1136\/gut.30.1.50","article-title":"Smoking delays gastric emptying of solids","volume":"30","author":"Miller","year":"1989","journal-title":"Gut"},{"key":"10.1053\/j.gastro.2009.12.057_bib46","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/0016-5085(93)90408-5","article-title":"Effect of cigarette smoking on solid and liquid intragastric distribution and gastric emptying","volume":"104","author":"Scott","year":"1993","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2009.12.057_bib47","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1111\/j.1572-0241.2003.07389.x","article-title":"Symptoms associated with impaired gastric emptying of solid and liquids in functional dyspepsia","volume":"98","author":"Sarnelli","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2009.12.057_bib48","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1111\/j.1572-0241.2004.30388.x","article-title":"Obesity and chronic gastrointestinal tract symptoms in young adults: a birth cohort study","volume":"99","author":"Talley","year":"2004","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2009.12.057_bib49","first-page":"1","article-title":"Symptom pattern and pathophysiological correlates of weight loss in tertiary-referred functional dyspepsia","volume":"30","author":"Tack","year":"2009","journal-title":"Neurogastroenterol Motil"},{"key":"10.1053\/j.gastro.2009.12.057_bib50","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1053\/j.gastro.2005.11.061","article-title":"Functional bowel disorders","volume":"130","author":"Longstreth","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2009.12.057_bib51","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1080\/00365520410008141","article-title":"Valid symptoms reporting at upper endoscopy in a random sample of the Swedish adult general population: the Kalixanda study","volume":"39","author":"Aro","year":"2004","journal-title":"Scand J Gastroenterol"}],"container-title":["Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508510000090?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508510000090?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T14:50:46Z","timestamp":1758034246000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016508510000090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4]]},"references-count":50,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,4]]}},"alternative-id":["S0016508510000090"],"URL":"https:\/\/doi.org\/10.1053\/j.gastro.2009.12.057","relation":{},"ISSN":["0016-5085"],"issn-type":[{"value":"0016-5085","type":"print"}],"subject":[],"published":{"date-parts":[[2010,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Epidemiology of Functional Dyspepsia and Subgroups in the Italian General Population: An Endoscopic Study","name":"articletitle","label":"Article Title"},{"value":"Gastroenterology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.gastro.2009.12.057","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 AGA Institute. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}