{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T22:58:04Z","timestamp":1789340284715,"version":"build-2803163510"},"reference-count":49,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T00:00:00Z","timestamp":1317427200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gastroenterology"],"published-print":{"date-parts":[[2011,10]]},"DOI":"10.1053\/j.gastro.2011.06.084","type":"journal-article","created":{"date-parts":[[2011,7,22]],"date-time":"2011-07-22T13:23:58Z","timestamp":1311341038000},"page":"1187-1193","source":"Crossref","is-referenced-by-count":99,"title":["The Prevalence of Celiac Disease Among Patients With Nonconstipated Irritable Bowel Syndrome Is Similar to Controls"],"prefix":"10.1053","volume":"141","author":[{"given":"Brooks D.","family":"Cash","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel H.","family":"Rubenstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick E.","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Gentry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Borko","family":"Nojkov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. Hirsohi","family":"Andrews","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Dobhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William D.","family":"Chey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/j.gastro.2011.06.084_bib1","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1146\/annurev.med.52.1.319","article-title":"Irritable bowel syndrome","volume":"52","author":"Ringel","year":"2001","journal-title":"Annu Rev Med"},{"key":"10.1053\/j.gastro.2011.06.084_bib2","first-page":"495","article-title":"Prevalence of irritable bowel syndrome: a community survey","volume":"54","author":"Wilson","year":"2004","journal-title":"Br J Gen Pract"},{"key":"10.1053\/j.gastro.2011.06.084_bib3","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1111\/j.1365-2036.2004.02034.x","article-title":"Prevalence of irritable bowel syndrome according to different diagnostic criteria in a non-selected adult population","volume":"20","author":"Hillil\u00e4","year":"2004","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1053\/j.gastro.2011.06.084_bib4","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.1038\/ajg.2009.232","article-title":"Developing valid and reliable health utilities in irritable bowel syndrome: results from the IBS PROOF cohort","volume":"104","author":"Spiegel","year":"2009","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2011.06.084_bib5","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1111\/j.1572-0241.2003.07296.x","article-title":"Irritable bowel syndrome health care use and costs: a US managed care perspective","volume":"98","author":"Longstreth","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2011.06.084_bib6","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1001\/archinte.163.8.929","article-title":"The economic consequences of irritable bowel syndrome: a US employer perspective","volume":"163","author":"Leong","year":"2003","journal-title":"Arch Intern Med"},{"key":"10.1053\/j.gastro.2011.06.084_bib7","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1038\/ajg.2010.64","article-title":"Introduction: a practical evidence based approach to the diagnosis of functional gastrointestinal disorders","volume":"105","author":"Kellow","year":"2010","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2011.06.084_bib8","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1136\/bmj.2.6138.653","article-title":"Towards a positive diagnosis of the irritable bowel syndrome","volume":"2","author":"Manning","year":"1978","journal-title":"Br Med J"},{"key":"10.1053\/j.gastro.2011.06.084_bib9","first-page":"159","article-title":"Identification of sub-groups of functional gastrointestinal disorders","volume":"3","author":"Drossman","year":"1990","journal-title":"Gastroenterol Int"},{"key":"10.1053\/j.gastro.2011.06.084_bib10","series-title":"The functional gastrointestinal disorders: diagnosis, pathophysiology, and treatment","author":"Drossman","year":"1994"},{"issue":"Suppl II","key":"10.1053\/j.gastro.2011.06.084_bib11","first-page":"43","article-title":"Functional bowel disorders and functional abdominal pain","volume":"45","author":"Thompson","year":"1999","journal-title":"Gut"},{"key":"10.1053\/j.gastro.2011.06.084_bib12","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1053\/j.gastro.2005.11.061","article-title":"Functional bowel disorders","volume":"130","author":"Longstreth","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2011.06.084_bib13","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1038\/ajg.2010.56","article-title":"Validation of symptom-based diagnostic criteria for irritable bowel syndrome: a critical review","volume":"105","author":"Whitehead","year":"2010","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2011.06.084_bib14","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1007\/s00251-010-0465-9","article-title":"Celiac disease: how complicated can it get?","volume":"62","author":"Tjon","year":"2010","journal-title":"Immunogenetics"},{"key":"10.1053\/j.gastro.2011.06.084_bib15","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1001\/archinternmed.2009.22","article-title":"Yield of diagnostic tests for celiac disease in individuals with symptoms suggestive of irritable bowel syndrome: systematic review and meta-analysis","volume":"169","author":"Ford","year":"2009","journal-title":"Arch Int Med"},{"key":"10.1053\/j.gastro.2011.06.084_bib16","doi-asserted-by":"crossref","DOI":"10.1111\/j.1572-0241.2002.07027.x","article-title":"The utility of diagnostic tests in irritable bowel syndrome patients: a systematic review","volume":"97","author":"Cash","year":"2002","journal-title":"Am J Gastroenterol"},{"issue":"Suppl 1","key":"10.1053\/j.gastro.2011.06.084_bib17","first-page":"S1","article-title":"American College of Gastroenterology Task Force on Irritable Bowel Syndrome","volume":"104","author":"Brandt","year":"2009","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2011.06.084_bib18","series-title":"ROME II: The functional gastrointestinal disorders. Diagnosis, pathophysiology and treatment: a multinational consensus (2000)","year":"2000"},{"key":"10.1053\/j.gastro.2011.06.084_bib19","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1001\/archinte.163.3.286","article-title":"Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large, multicenter study","volume":"163","author":"Fasano","year":"2003","journal-title":"Arch Int Med"},{"key":"10.1053\/j.gastro.2011.06.084_bib20","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1016\/S0140-6736(01)06581-3","article-title":"Association of adult coeliac disease with irritable bowel syndrome: a case-control study in patients fulfilling ROME II criteria referred to secondary care","volume":"358","author":"Sanders","year":"2001","journal-title":"Lancet"},{"key":"10.1053\/j.gastro.2011.06.084_bib21","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1542\/peds.107.1.42","article-title":"Serological screening for celiac disease in healthy 2.5-year-old children in Sweden","volume":"107","author":"Carlsson","year":"2001","journal-title":"Pediatrics"},{"key":"10.1053\/j.gastro.2011.06.084_bib22","doi-asserted-by":"crossref","first-page":"S57","DOI":"10.1053\/j.gastro.2005.02.014","article-title":"The prevalence of celiac disease in average-risk and at-risk Western European populations: a systematic review","volume":"128","author":"Dube","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2011.06.084_bib23","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/S0140-6736(94)90989-X","article-title":"Coeliac disease in the year 2000: exploring the iceberg","volume":"343","author":"Catassi","year":"1994","journal-title":"Lancet"},{"key":"10.1053\/j.gastro.2011.06.084_bib24","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1046\/j.1440-1746.2000.02290.x","article-title":"Adult coeliac disease: prevalence and clinical significance","volume":"15","author":"Cook","year":"2000","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2011.06.084_bib25","first-page":"403","article-title":"The prevalence of celiac disease in patients with irritable bowel syndrome","volume":"4","author":"El-Salhy","year":"2011","journal-title":"Mol Med Rep"},{"key":"10.1053\/j.gastro.2011.06.084_bib26","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1038\/ajg.2011.21","article-title":"Screening for celiac disease in a North American population: sequential serology and gastrointestinal symptoms","volume":"106","author":"Katz","year":"2011","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2011.06.084_bib27","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1053\/j.gastro.2010.04.007","article-title":"Detection of celiac disease and lymphocytic enteropathy by parallel serology and histopathology in a population based study","volume":"139","author":"Walker","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2011.06.084_bib28","doi-asserted-by":"crossref","first-page":"476","DOI":"10.4065\/79.4.476","article-title":"Celiac disease serology in irritable bowel syndrome and dyspepsia: a population-based case-control study","volume":"79","author":"Locke","year":"2004","journal-title":"Mayo Clin Proc"},{"key":"10.1053\/j.gastro.2011.06.084_bib29","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1046\/j.1365-2036.2003.01666.x","article-title":"Coeliac disease presenting with symptoms of irritable bowel syndrome","volume":"18","author":"Shahbazkhani","year":"2003","journal-title":"Aliment Pharmacol"},{"key":"10.1053\/j.gastro.2011.06.084_bib30","first-page":"105","article-title":"Endomysium antibodies are superior to gliadin antibodies in screening for coeliac disease in patients presenting supposed functional gastrointestinal symptoms","volume":"18","author":"Aregus","year":"2000","journal-title":"Scand J Gastroenterol"},{"key":"10.1053\/j.gastro.2011.06.084_bib31","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1097\/00042737-200304000-00012","article-title":"A primary care cross-sectional study of undiagnosed coeliac disease","volume":"15","author":"Sanders","year":"2003","journal-title":"Eur J Gastroenterol Hepatol"},{"issue":"Suppl 1","key":"10.1053\/j.gastro.2011.06.084_bib32","first-page":"A147","article-title":"Screening for celiac sprue in patients with suspected irritable bowel syndrome: results from a prospective US multi-center trial","volume":"132","author":"Chey","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2011.06.084_bib33","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.1007\/s10620-007-0082-0","article-title":"Association of gluten enteropathy and irritable bowel syndrome in adult Turkish population","volume":"53","author":"Ozdil","year":"2008","journal-title":"Dig Dis Sci"},{"key":"10.1053\/j.gastro.2011.06.084_bib34","series-title":"Celiac disease","author":"Rostom","year":"2004"},{"key":"10.1053\/j.gastro.2011.06.084_bib35","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.cgh.2007.03.021","article-title":"Predictors of clinical response to gluten-free diet in patients diagnosed with diarrhea predominant irritable bowel syndrome","volume":"5","author":"Wahnschaffe","year":"2007","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2011.06.084_bib36","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1038\/ajg.2009.188","article-title":"Between celiac disease and irritable bowel syndrome: the \u201cno man's land\u201d of gluten sensitivity","volume":"104","author":"Verdu","year":"2009","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2011.06.084_bib37","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1741-7015-9-23","article-title":"Divergence of gut permeability and mucosal immune gene expression in two gluten-associated conditions: celiac disease and gluten sensitivity","volume":"9","author":"Sapone","year":"2011","journal-title":"BMC Med"},{"key":"10.1053\/j.gastro.2011.06.084_bib38","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1016\/j.jada.2009.04.012","article-title":"The role of diet in symptoms of irritable bowel syndrome in adults: a narrative review","volume":"109","author":"Heizer","year":"2009","journal-title":"J Am Diet Assoc"},{"key":"10.1053\/j.gastro.2011.06.084_bib39","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1111\/j.1572-0241.2004.40266.x","article-title":"Dietary fructose and gastrointestinal symptoms: a review","volume":"99","author":"Skoog","year":"2004","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2011.06.084_bib40","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1016\/j.jada.2006.07.010","article-title":"Fructose malabsorption and symptoms of irritable bowel syndrome: guidelines for effective dietary management","volume":"106","author":"Shepherd","year":"2006","journal-title":"J Am Diet Assoc"},{"key":"10.1053\/j.gastro.2011.06.084_bib41","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1016\/j.gie.2007.10.015","article-title":"How many duodenal biopsy specimens are required to make a diagnosis of celiac disease?","volume":"67","author":"Pais","year":"2008","journal-title":"Gastrointest Endosc"},{"key":"10.1053\/j.gastro.2011.06.084_bib42","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/S0016-5107(03)01999-0","article-title":"High-magnification immersion chromoscopic duodenoscopy permits visualization of patchy atrophy in celiac disease: an opportunity to target biopsies of abnormal mucosa (Letter)","volume":"58","author":"Hurlstone","year":"2003","journal-title":"Gastrointest Endosc"},{"key":"10.1053\/j.gastro.2011.06.084_bib43","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1038\/ajg.2010.153","article-title":"How patchy is patchy villous atrophy?","volume":"105","author":"Ravelli","year":"2010","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2011.06.084_bib44","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1097\/MCG.0b013e31815b9d11","article-title":"Assessment of the diagnostic value of duodenal bulb histology in patients with celiac disease, using multiple biopsy sites","volume":"43","author":"Prasad","year":"2009","journal-title":"J Clin Gastroenterol"},{"key":"10.1053\/j.gastro.2011.06.084_bib45","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.cgh.2007.03.019","article-title":"Comparison of the interobserver reproducibility with different histologic criteria used in celiac disease","volume":"5","author":"Corazza","year":"2007","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2011.06.084_bib46","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1053\/j.gastro.2004.03.012","article-title":"Testing for celiac sprue in irritable bowel syndrome with predominant diarrhea: a cost effectiveness analysis","volume":"126","author":"Spiegel","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2011.06.084_bib47","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1111\/j.1365-2036.2004.01958.x","article-title":"Serological testing for coeliac disease in patients with symptoms of irritable bowel syndrome: a cost-effectiveness analysis","volume":"19","author":"Mein","year":"2004","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1053\/j.gastro.2011.06.084_bib48","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1053\/gast.2002.37095b","article-title":"American Gastroenterological Association Medical Position Statement: irritable bowel syndrome","volume":"123","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2011.06.084_bib49","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1136\/gut.2007.119446","article-title":"Guidelines on the irritable bowel syndrome: mechanisms and practical management","volume":"56","author":"Spiller","year":"2007","journal-title":"Gut"}],"container-title":["Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508511009395?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508511009395?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T07:24:27Z","timestamp":1543649067000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016508511009395"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10]]},"references-count":49,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,10]]}},"alternative-id":["S0016508511009395"],"URL":"https:\/\/doi.org\/10.1053\/j.gastro.2011.06.084","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.13468957.14848055","asserted-by":"object"}]},"ISSN":["0016-5085"],"issn-type":[{"value":"0016-5085","type":"print"}],"subject":[],"published":{"date-parts":[[2011,10]]}}}