{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T21:15:15Z","timestamp":1786482915451,"version":"build-2736575974"},"reference-count":49,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,11,17]],"date-time":"2014-11-17T00:00:00Z","timestamp":1416182400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","gastrojournal.org","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastroenterology"],"published-print":{"date-parts":[[2015,2]]},"DOI":"10.1053\/j.gastro.2014.10.041","type":"journal-article","created":{"date-parts":[[2014,11,5]],"date-time":"2014-11-05T13:01:50Z","timestamp":1415192510000},"page":"367-378","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":100,"title":["Polymorphisms Near TBX5 and GDF7 Are Associated With Increased Risk for Barrett\u2019s Esophagus"],"prefix":"10.1053","volume":"148","author":[{"given":"Claire","family":"Palles","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Chegwidden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinzhong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John M.","family":"Findlay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Garry","family":"Farnham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesc","family":"Castro Giner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maikel P.","family":"Peppelenbosch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Kovac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire L.","family":"Adams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Prenen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Briggs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Harrison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Sanders","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"MacDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Haigh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Art","family":"Tucker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Love","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoj","family":"Nanji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"deCaestecker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Ferry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barrie","family":"Rathbone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Hapeshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugh","family":"Barr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Moayyedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Watson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Zietek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neera","family":"Maroo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Gay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Underwood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Boulter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugh","family":"McMurtry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Monk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Praful","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krish","family":"Ragunath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Al Dulaimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iain","family":"Murray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konrad","family":"Koss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Veitch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigel","family":"Trudgill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuka","family":"Nwokolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bjorn","family":"Rembacken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Atherfold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaine","family":"Green","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeng","family":"Ang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernst J.","family":"Kuipers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wu","family":"Chow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart","family":"Paterson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudarshan","family":"Kadri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Beales","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Grimley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Mullins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Conrad","family":"Beckett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Farrant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Dixon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahjehan","family":"Wajed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjan","family":"Dhar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elinor","family":"Sawyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Roylance","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn","family":"Onstad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marilie D.","family":"Gammon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas A.","family":"Corley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas J.","family":"Shaheen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigel C.","family":"Bird","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura J.","family":"Hardie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian J.","family":"Reid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weimin","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvonne","family":"Romero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslie","family":"Bernstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna H.","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan G.","family":"Casson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Fitzgerald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Whiteman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harvey A.","family":"Risch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David M.","family":"Levine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom L.","family":"Vaughan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Auke P.","family":"Verhaar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"van den Brande","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eelke L.","family":"Toxopeus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manon C.","family":"Spaander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bas P.L.","family":"Wijnhoven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc J.W.","family":"van der Laan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kausilia","family":"Krishnadath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cisca","family":"Wijmenga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gosia","family":"Trynka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ross","family":"McManus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John V.","family":"Reynolds","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacintha","family":"O\u2019Sullivan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Padraic","family":"MacMathuna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah A.","family":"McGarrigle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dermot","family":"Kelleher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Severine","family":"Vermeire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Cleynen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raf","family":"Bisschops","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Tomlinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janusz","family":"Jankowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/j.gastro.2014.10.041_bib1","doi-asserted-by":"crossref","first-page":"c4551","DOI":"10.1136\/bmj.c4551","article-title":"Diagnosis and management of Barrett's oesophagus","volume":"341","author":"Jankowski","year":"2010","journal-title":"BMJ"},{"key":"10.1053\/j.gastro.2014.10.041_bib2","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1038\/ajg.2008.172","article-title":"Biomarkers in gastroenterology; between hype and hope comes histopathology","volume":"104","author":"Jankowski","year":"2009","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2014.10.041_bib3","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/j.cgh.2013.02.017","article-title":"Association between markers of obesity and progression from Barrett's esophagus to esophageal adenocarcinoma","volume":"11","author":"Duggan","year":"2013","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2014.10.041_bib4","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1016\/j.cgh.2013.03.024","article-title":"Association of Barrett's esophagus with type II diabetes mellitus: results from a large population-based case-control study","volume":"11","author":"Iyer","year":"2013","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2014.10.041_bib5","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1111\/nyas.12253","article-title":"Defining esophageal landmarks, gastroesophageal reflux disease, and Barrett's esophagus","volume":"1300","author":"DeVault","year":"2013","journal-title":"Ann N Y Acad Sci"},{"key":"10.1053\/j.gastro.2014.10.041_bib6","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1053\/gast.2002.30301","article-title":"Gastroesophageal reflux disease in monozygotic and dizygotic twins","volume":"122","author":"Cameron","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2014.10.041_bib7","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1136\/gut.52.8.1085","article-title":"Genetic influences in gastro-oesophageal reflux disease: a twin study","volume":"52","author":"Mohammed","year":"2003","journal-title":"Gut"},{"key":"10.1053\/j.gastro.2014.10.041_bib8","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1111\/j.1365-2036.2007.03326.x","article-title":"Influence of genetics on irritable bowel syndrome, gastro-oesophageal reflux and dyspepsia: a twin study","volume":"25","author":"Lembo","year":"2007","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1053\/j.gastro.2014.10.041_bib9","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1080\/00365520510023189","article-title":"A\u00a0family history of Barrett's oesophagus: another risk factor?","volume":"40","author":"Groves","year":"2005","journal-title":"Scand J Gastroenterol"},{"key":"10.1053\/j.gastro.2014.10.041_bib10","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1158\/1055-9965.EPI-06-0293","article-title":"Familiality in Barrett's esophagus, adenocarcinoma of the esophagus, and adenocarcinoma of the gastroesophageal junction","volume":"15","author":"Chak","year":"2006","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1053\/j.gastro.2014.10.041_bib11","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1038\/ng.2408","article-title":"Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus","volume":"44","author":"Su","year":"2012","journal-title":"Nat Genet"},{"key":"10.1053\/j.gastro.2014.10.041_bib12","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1038\/ng.2796","article-title":"A\u00a0genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus","volume":"45","author":"Levine","year":"2013","journal-title":"Nat Genet"},{"key":"10.1053\/j.gastro.2014.10.041_bib13","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1093\/jnci\/djt303","article-title":"Germline genetic contributions to risk for esophageal adenocarcinoma, Barrett's esophagus, and gastroesophageal reflux","volume":"105","author":"Ek","year":"2013","journal-title":"J\u00a0Natl Cancer Inst"},{"key":"10.1053\/j.gastro.2014.10.041_bib14","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1002\/ijc.28160","article-title":"Barrett associated MHC and FOXF1 variants also increase esophageal carcinoma risk","volume":"133","author":"Dura","year":"2013","journal-title":"Int J Cancer"},{"key":"10.1053\/j.gastro.2014.10.041_bib15","doi-asserted-by":"crossref","first-page":"e22493","DOI":"10.1371\/journal.pone.0022493","article-title":"Barx1-mediated inhibition of Wnt signaling in the mouse thoracic foregut controls tracheo-esophageal septation and epithelial differentiation","volume":"6","author":"Woo","year":"2011","journal-title":"PLoS One"},{"key":"10.1053\/j.gastro.2014.10.041_bib16","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1242\/dev.02846","article-title":"Foxp2 and Foxp1 cooperatively regulate lung and esophagus development","volume":"134","author":"Shu","year":"2007","journal-title":"Development"},{"key":"10.1053\/j.gastro.2014.10.041_bib17","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1136\/bmj.332.7556.1512","article-title":"Improving surveillance for Barrett's oesophagus: AspECT and BOSS trials provide an evidence base","volume":"332","author":"Jankowski","year":"2006","journal-title":"BMJ"},{"key":"10.1053\/j.gastro.2014.10.041_bib18","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1053\/j.gastro.2006.08.032","article-title":"The development and validation of an endoscopic grading system for Barrett's esophagus: the Prague C & M criteria","volume":"131","author":"Sharma","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2014.10.041_bib19","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1053\/j.gastro.2012.04.032","article-title":"Consensus statements for management of Barrett's dysplasia and early-stage esophageal adenocarcinoma, based on a Delphi process (BADCAT)","volume":"143","author":"Bennett","year":"2012","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2014.10.041_bib20","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1038\/ng.670","article-title":"Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33","volume":"42","author":"Houlston","year":"2010","journal-title":"Nat Genet"},{"key":"10.1053\/j.gastro.2014.10.041_bib21","first-page":"1053","article-title":"Germline CDH1 mutations in bilateral lobular carcinoma in situ","volume":"100","author":"Petridis","year":"2013","journal-title":"Br J Cancer"},{"key":"10.1053\/j.gastro.2014.10.041_bib22","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1038\/ng.998","article-title":"Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease","volume":"43","author":"Trynka","year":"2011","journal-title":"Nat Genet"},{"key":"10.1053\/j.gastro.2014.10.041_bib23","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1001\/jama.2011.1029","article-title":"Germline mutations in MSR1, ASCC1, and CTHRC1 in patients with Barrett esophagus and esophageal adenocarcinoma","volume":"306","author":"Orloff","year":"2011","journal-title":"JAMA"},{"key":"10.1053\/j.gastro.2014.10.041_bib24","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1053\/j.gastro.2010.04.014","article-title":"A\u00a0population-based study of IGF axis polymorphisms and the esophageal inflammation, metaplasia, adenocarcinoma sequence","volume":"139","author":"McElholm","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2014.10.041_bib25","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1186\/1471-2105-11-288","article-title":"GWAMA: software for genome-wide association meta-analysis","volume":"11","author":"Magi","year":"2010","journal-title":"BMC Bioinform"},{"key":"10.1053\/j.gastro.2014.10.041_bib26","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"10.1053\/j.gastro.2014.10.041_bib27","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1038\/ng.2293","article-title":"Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk","volume":"44","author":"Dunlop","year":"2012","journal-title":"Nat Genet"},{"key":"10.1053\/j.gastro.2014.10.041_bib28","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1038\/nmeth.2307","article-title":"Improved whole-chromosome phasing for disease and population genetic studies","volume":"10","author":"Delaneau","year":"2013","journal-title":"Nat Methods"},{"key":"10.1053\/j.gastro.2014.10.041_bib29","doi-asserted-by":"crossref","first-page":"e1000529","DOI":"10.1371\/journal.pgen.1000529","article-title":"A\u00a0flexible and accurate genotype imputation method for the next generation of genome-wide association studies","volume":"5","author":"Howie","year":"2009","journal-title":"PLoS Genet"},{"key":"10.1053\/j.gastro.2014.10.041_bib30","doi-asserted-by":"crossref","first-page":"D930","DOI":"10.1093\/nar\/gkr917","article-title":"HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants","volume":"40","author":"Ward","year":"2012","journal-title":"Nucleic Acids Res"},{"key":"10.1053\/j.gastro.2014.10.041_bib31","doi-asserted-by":"crossref","first-page":"e164","DOI":"10.1093\/nar\/gkq603","article-title":"ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data","volume":"38","author":"Wang","year":"2010","journal-title":"Nucleic Acids Res"},{"key":"10.1053\/j.gastro.2014.10.041_bib32","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1101\/gr.137323.112","article-title":"Annotation of functional variation in personal genomes using RegulomeDB","volume":"22","author":"Boyle","year":"2012","journal-title":"Genome Res"},{"key":"10.1053\/j.gastro.2014.10.041_bib33","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1038\/ng.2591","article-title":"Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity","volume":"45","author":"Dulak","year":"2013","journal-title":"Nat Genet"},{"key":"10.1053\/j.gastro.2014.10.041_bib34","doi-asserted-by":"crossref","first-page":"e10693","DOI":"10.1371\/journal.pone.0010693","article-title":"Genetics and beyond\u2014the transcriptome of human monocytes and disease susceptibility","volume":"5","author":"Zeller","year":"2010","journal-title":"PLoS One"},{"key":"10.1053\/j.gastro.2014.10.041_bib35","doi-asserted-by":"crossref","first-page":"e1002003","DOI":"10.1371\/journal.pgen.1002003","article-title":"The architecture of gene regulatory variation across multiple human tissues: the MuTHER study","volume":"7","author":"Nica","year":"2011","journal-title":"PLoS Genet"},{"key":"10.1053\/j.gastro.2014.10.041_bib36","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/s11605-011-1758-5","article-title":"Activation of the BMP4 pathway and early expression of CDX2 characterize non-specialized columnar metaplasia in a human model of Barrett's esophagus","volume":"16","author":"Castillo","year":"2012","journal-title":"J\u00a0Gastrointest Surg"},{"key":"10.1053\/j.gastro.2014.10.041_bib37","doi-asserted-by":"crossref","first-page":"128","DOI":"10.3109\/08977194.2011.593178","article-title":"Divergent activities of osteogenic BMP2, and tenogenic BMP12 and BMP13 independent of receptor binding affinities","volume":"29","author":"Berasi","year":"2011","journal-title":"Growth Factors"},{"key":"10.1053\/j.gastro.2014.10.041_bib38","doi-asserted-by":"crossref","first-page":"3549","DOI":"10.1242\/dev.01915","article-title":"Direct and indirect roles of CNS dorsal midline cells in choroid plexus epithelia formation","volume":"132","author":"Currle","year":"2005","journal-title":"Development"},{"key":"10.1053\/j.gastro.2014.10.041_bib39","doi-asserted-by":"crossref","first-page":"e1002866","DOI":"10.1371\/journal.pgen.1002866","article-title":"Multiple roles and interactions of Tbx4 and Tbx5 in development of the respiratory system","volume":"8","author":"Arora","year":"2012","journal-title":"PLoS Genet"},{"key":"10.1053\/j.gastro.2014.10.041_bib40","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1097\/00001573-200405000-00004","article-title":"TBX5 mutations and congenital heart disease: Holt-Oram syndrome revealed","volume":"19","author":"Mori","year":"2004","journal-title":"Curr Opin Cardiol"},{"key":"10.1053\/j.gastro.2014.10.041_bib41","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1038\/ng.403","article-title":"The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer","volume":"41","author":"Pomerantz","year":"2009","journal-title":"Nat Genet"},{"key":"10.1053\/j.gastro.2014.10.041_bib42","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1038\/ng.406","article-title":"The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling","volume":"41","author":"Tuupanen","year":"2009","journal-title":"Nat Genet"},{"key":"10.1053\/j.gastro.2014.10.041_bib43","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1101\/gr.152942.112","article-title":"CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer","volume":"23","author":"Ling","year":"2013","journal-title":"Genome Res"},{"key":"10.1053\/j.gastro.2014.10.041_bib44","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1245\/s10434-012-2657-z","article-title":"The rs6983267 SNP is associated with MYC transcription efficiency, which promotes progression and worsens prognosis of colorectal cancer","volume":"20","author":"Takatsuno","year":"2013","journal-title":"Ann Surg Oncol"},{"key":"10.1053\/j.gastro.2014.10.041_bib45","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1242\/dev.128.12.2397","article-title":"Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations","volume":"128","author":"Mahlapuu","year":"2001","journal-title":"Development"},{"key":"10.1053\/j.gastro.2014.10.041_bib46","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.ejmg.2009.10.001","article-title":"Genetic factors in esophageal atresia, tracheo-esophageal fistula and the VACTERL association: roles for FOXF1 and the 16q24.1 FOX transcription factor gene cluster, and review of the literature","volume":"53","author":"Shaw-Smith","year":"2010","journal-title":"Eur J Med Genet"},{"key":"10.1053\/j.gastro.2014.10.041_bib47","first-page":"1172","article-title":"Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia","volume":"10","author":"Wang","year":"2014","journal-title":"J\u00a0Clin Invest"},{"key":"10.1053\/j.gastro.2014.10.041_bib48","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1124\/jpet.106.108175","article-title":"The role of retinoid X receptor alpha in regulating alcohol metabolism","volume":"319","author":"Gyamfi","year":"2006","journal-title":"J\u00a0Pharmacol Exp Ther"},{"key":"10.1053\/j.gastro.2014.10.041_bib49","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1016\/j.ajhg.2012.10.010","article-title":"Improved heritability estimation from genome-wide SNPs","volume":"91","author":"Speed","year":"2012","journal-title":"Am J Hum Genet"}],"container-title":["Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508514013341?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508514013341?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,4,21]],"date-time":"2022-04-21T09:09:28Z","timestamp":1650532168000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016508514013341"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":49,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["S0016508514013341"],"URL":"https:\/\/doi.org\/10.1053\/j.gastro.2014.10.041","relation":{},"ISSN":["0016-5085"],"issn-type":[{"value":"0016-5085","type":"print"}],"subject":[],"published":{"date-parts":[[2015,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Polymorphisms Near TBX5 and GDF7 Are Associated With Increased Risk for Barrett\u2019s Esophagus","name":"articletitle","label":"Article Title"},{"value":"Gastroenterology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.gastro.2014.10.041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 AGA Institute. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}