{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T00:14:43Z","timestamp":1793146483471,"version":"4.5.0"},"reference-count":17,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","gastrojournal.org","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastroenterology"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1053\/j.gastro.2016.08.055","type":"journal-article","created":{"date-parts":[[2016,9,30]],"date-time":"2016-09-30T19:48:56Z","timestamp":1475264936000},"page":"1100-1104","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":189,"title":["Interleukin 1\u03b2 Mediates Intestinal Inflammation in Mice and Patients With Interleukin 10 Receptor Deficiency"],"prefix":"10.1053","volume":"151","author":[{"given":"Dror S.","family":"Shouval","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4299-1001","authenticated-orcid":false,"given":"Amlan","family":"Biswas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9081-3969","authenticated-orcid":false,"given":"Yu Hui","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra E.","family":"Griffith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4804-5497","authenticated-orcid":false,"given":"Liza","family":"Konnikova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan D.","family":"Mascanfroni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naresh S.","family":"Redhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra M.","family":"Frei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4003-0568","authenticated-orcid":false,"given":"Michael","family":"Field","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andria L.","family":"Doty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey D.","family":"Goldsmith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atul K.","family":"Bhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Loizides","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Batia","family":"Weiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baruch","family":"Yerushalmi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadahiro","family":"Yanagi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuli","family":"Lui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco J.","family":"Quintana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleixo M.","family":"Muise","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0956-0445","authenticated-orcid":false,"given":"Christoph","family":"Klein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce H.","family":"Horwitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah C.","family":"Glover","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athos","family":"Bousvaros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott B.","family":"Snapper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/j.gastro.2016.08.055_bib1","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/B978-0-12-800267-4.00005-5","volume":"122","author":"Shouval","year":"2014","journal-title":"Adv Immunol"},{"key":"10.1053\/j.gastro.2016.08.055_bib2","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1053\/j.gastro.2012.04.045","volume":"143","author":"Kotlarz","year":"2012","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2016.08.055_bib3","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1056\/NEJMoa0907206","volume":"361","author":"Glocker","year":"2009","journal-title":"N\u00a0Engl J Med"},{"key":"10.1053\/j.gastro.2016.08.055_bib4","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1016\/j.immuni.2014.03.011","volume":"40","author":"Shouval","year":"2014","journal-title":"Immunity"},{"key":"10.1053\/j.gastro.2016.08.055_bib5","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.immuni.2014.03.012","volume":"40","author":"Zigmond","year":"2014","journal-title":"Immunity"},{"key":"10.1053\/j.gastro.2016.08.055_bib6","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1038\/mi.2013.103","volume":"7","author":"Li","year":"2014","journal-title":"Mucosal Immunol"},{"key":"10.1053\/j.gastro.2016.08.055_bib7","doi-asserted-by":"crossref","first-page":"6131","DOI":"10.1038\/ncomms7131","volume":"6","author":"Li","year":"2015","journal-title":"Nat Commun"},{"key":"10.1053\/j.gastro.2016.08.055_bib8","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/j.immuni.2013.11.010","volume":"39","author":"Garlanda","year":"2013","journal-title":"Immunity"},{"key":"10.1053\/j.gastro.2016.08.055_bib9","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/j.cell.2014.04.007","volume":"157","author":"Lamkanfi","year":"2014","journal-title":"Cell"},{"key":"10.1053\/j.gastro.2016.08.055_bib10","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1084\/jem.20111453","volume":"209","author":"Coccia","year":"2012","journal-title":"J\u00a0Exp Med"},{"key":"10.1053\/j.gastro.2016.08.055_bib11","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/j.immuni.2016.01.012","volume":"44","author":"Gaidt","year":"2016","journal-title":"Immunity"},{"key":"10.1053\/j.gastro.2016.08.055_bib12","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1038\/mi.2014.1","volume":"7","author":"Zhang","year":"2014","journal-title":"Mucosal Immunol"},{"key":"10.1053\/j.gastro.2016.08.055_bib13","doi-asserted-by":"crossref","first-page":"14488","DOI":"10.1038\/srep14488","volume":"5","author":"Gurung","year":"2015","journal-title":"Sci Rep"},{"key":"10.1053\/j.gastro.2016.08.055_bib14","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.immuni.2011.02.006","volume":"34","author":"Guarda","year":"2011","journal-title":"Immunity"},{"key":"10.1053\/j.gastro.2016.08.055_bib15","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1038\/mi.2015.109","volume":"9","author":"Filardy","year":"2016","journal-title":"Mucosal Immunol"},{"key":"10.1053\/j.gastro.2016.08.055_bib16","doi-asserted-by":"crossref","first-page":"e535","DOI":"10.1542\/peds.2010-2192","volume":"129","author":"Ruiz Gomez","year":"2012","journal-title":"Pediatrics"},{"key":"10.1053\/j.gastro.2016.08.055_bib17","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1002\/ibd.22974","volume":"19","author":"Moran","year":"2013","journal-title":"Inflamm Bowel Dis"}],"container-title":["Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508516350351?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508516350351?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,2,24]],"date-time":"2020-02-24T09:50:06Z","timestamp":1582537806000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016508516350351"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["S0016508516350351"],"URL":"https:\/\/doi.org\/10.1053\/j.gastro.2016.08.055","relation":{},"ISSN":["0016-5085"],"issn-type":[{"value":"0016-5085","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Interleukin 1\u03b2 Mediates Intestinal Inflammation in Mice and Patients With Interleukin 10 Receptor Deficiency","name":"articletitle","label":"Article Title"},{"value":"Gastroenterology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.gastro.2016.08.055","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 by the AGA Institute","name":"copyright","label":"Copyright"}]}}