{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T15:47:01Z","timestamp":1784821621086,"version":"3.55.0"},"reference-count":43,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","gastrojournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastroenterology"],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.1053\/j.gastro.2016.12.009","type":"journal-article","created":{"date-parts":[[2016,12,22]],"date-time":"2016-12-22T17:48:04Z","timestamp":1482428884000},"page":"1002-1013.e9","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":59,"title":["Detection of Sessile Serrated Adenomas in the Proximal Colon Using Wide-Field Fluorescence Endoscopy"],"prefix":"10.1053","volume":"152","author":[{"given":"Bishnu P.","family":"Joshi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenzhen","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenghong","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong Hoon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Navin","family":"Ghimire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anoop","family":"Prabhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik J.","family":"Wamsteker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard S.","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace H.","family":"Elta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena M.","family":"Stoffel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asha","family":"Pant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tonya","family":"Kaltenbach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy M.","family":"Soetikno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry D.","family":"Appelman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rork","family":"Kuick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. Kim","family":"Turgeon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas D.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/j.gastro.2016.12.009_bib1","first-page":"87","article-title":"Global cancer statistics, 2012","volume":"65","author":"Torre","year":"2015","journal-title":"CA Cancer J Clin"},{"issue":"Suppl 4","key":"10.1053\/j.gastro.2016.12.009_bib2","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1111\/jgh.12293","article-title":"Obesity: an epidemiological perspective from Asia and its relationship to gastrointestinal and liver cancers","volume":"28","author":"Goh","year":"2013","journal-title":"J\u00a0Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2016.12.009_bib3","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1053\/j.gastro.2010.06.052","article-title":"The reduction in colorectal cancer mortality after colonoscopy varies by site of the cancer","volume":"139","author":"Singh","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2016.12.009_bib4","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1093\/jnci\/djp436","article-title":"Protection from right- and left-sided colorectal neoplasms after colonoscopy: population-based study","volume":"102","author":"Brenner","year":"2010","journal-title":"J\u00a0Natl Cancer Inst"},{"key":"10.1053\/j.gastro.2016.12.009_bib5","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1056\/NEJMoa1301969","article-title":"Long-term colorectal-cancer incidence and mortality after lower endoscopy","volume":"369","author":"Nishihara","year":"2013","journal-title":"N\u00a0Engl J Med"},{"key":"10.1053\/j.gastro.2016.12.009_bib6","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/0092-8674(90)90186-I","article-title":"A\u00a0genetic model for colorectal tumorigenesis","volume":"61","author":"Fearon","year":"1990","journal-title":"Cell"},{"key":"10.1053\/j.gastro.2016.12.009_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.humpath.2010.06.002","article-title":"Update on the serrated pathway to colorectal carcinoma","volume":"42","author":"Snover","year":"2011","journal-title":"Hum Pathol"},{"key":"10.1053\/j.gastro.2016.12.009_bib8","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1038\/ajg.2010.429","article-title":"The clinical significance of serrated polyps","volume":"106","author":"Huang","year":"2011","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2016.12.009_bib9","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1038\/ajg.2012.161","article-title":"Serrated lesions of the colorectum: review and recommendations from an expert panel","volume":"107","author":"Rex","year":"2012","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2016.12.009_bib10","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1056\/NEJMoa043146","article-title":"Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer)","volume":"352","author":"Hampel","year":"2005","journal-title":"N\u00a0Engl J Med"},{"key":"10.1053\/j.gastro.2016.12.009_bib11","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.ccr.2013.05.014","article-title":"A\u00a0genetic progression model of Braf(V600E)-induced intestinal tumorigenesis reveals targets for therapeutic intervention","volume":"24","author":"Rad","year":"2013","journal-title":"Cancer Cell"},{"key":"10.1053\/j.gastro.2016.12.009_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ccr.2013.06.008","article-title":"BRAF: a driver of the serrated pathway in colon cancer","volume":"24","author":"Rustgi","year":"2013","journal-title":"Cancer Cell"},{"key":"10.1053\/j.gastro.2016.12.009_bib13","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1053\/j.gastro.2006.08.038","article-title":"High prevalence of sessile serrated adenomas with BRAF mutations: a prospective study of patients undergoing colonoscopy","volume":"131","author":"Spring","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2016.12.009_bib14","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/j.cgh.2013.11.034","article-title":"Endoscopic detection of proximal serrated lesions and pathologic identification of sessile serrated adenomas\/polyps vary on the basis of center","volume":"12","author":"Payne","year":"2014","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2016.12.009_bib15","doi-asserted-by":"crossref","first-page":"3087","DOI":"10.1021\/cr900361p","article-title":"Peptides and peptide hormones for molecular imaging and disease diagnosis","volume":"110","author":"Lee","year":"2010","journal-title":"Chem Rev"},{"key":"10.1053\/j.gastro.2016.12.009_bib16","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1038\/35101072","article-title":"Improving the efficacy of antibody-based cancer therapies","volume":"1","author":"Carter","year":"2001","journal-title":"Nat Rev Cancer"},{"key":"10.1053\/j.gastro.2016.12.009_bib17","doi-asserted-by":"crossref","first-page":"e102","DOI":"10.1038\/ctg.2015.28","article-title":"EGFR overexpressed in colonic neoplasia can be detected on wide-field endoscopic imaging","volume":"6","author":"Zhou","year":"2015","journal-title":"Clin Transl Gastroenterol"},{"key":"10.1053\/j.gastro.2016.12.009_bib18","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1021\/acs.bioconjchem.5b00565","article-title":"Design and synthesis of near-infrared peptide for in\u00a0vivo molecular imaging of HER2","volume":"27","author":"Joshi","year":"2016","journal-title":"Bioconjug Chem"},{"key":"10.1053\/j.gastro.2016.12.009_bib19","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.jcmgh.2015.12.001","article-title":"Claudin-1 peptide can detect colonic neoplasia in\u00a0vivo on endoscopic imaging","volume":"2","author":"Rabinsky","year":"2016","journal-title":"Cell Mol Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2016.12.009_bib20","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1038\/nm.3641","article-title":"Detection of colorectal polyps in humans using an intravenously administered fluorescent peptide targeted against c-Met","volume":"21","author":"Burggraaf","year":"2015","journal-title":"Nat Med"},{"key":"10.1053\/j.gastro.2016.12.009_bib21","first-page":"A1","article-title":"Multimodal endoscope can quantify wide-field fluorescence detection of Barrett's neoplasia","volume":"48","author":"Joshi","year":"2016","journal-title":"Endoscopy"},{"key":"10.1053\/j.gastro.2016.12.009_bib22","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1053\/j.gastro.2016.02.075","article-title":"Multimodal video colonoscope for targeted wide-field detection of nonpolypoid colorectal neoplasia","volume":"150","author":"Joshi","year":"2016","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2016.12.009_bib23","first-page":"2:e71","article-title":"Epigenetic and genetic features of 24 colon cancer cell lines","volume":"16","author":"Ahmed","year":"2013","journal-title":"Oncogenesis"},{"key":"10.1053\/j.gastro.2016.12.009_bib24","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1053\/j.gastro.2010.07.007","article-title":"Affinity peptide for targeted detection of dysplasia in Barrett's esophagus","volume":"139","author":"Li","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2016.12.009_bib25","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s10585-008-9220-0","article-title":"In\u00a0vitro binding evaluation of 177Lu-AMBA, a novel 177Lu-labeled GRP-R agonist for systemic radiotherapy in human tissues","volume":"26","author":"Thomas","year":"2009","journal-title":"Clin Exp Metastasis"},{"key":"10.1053\/j.gastro.2016.12.009_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.gie.2012.07.017","article-title":"Near-infrared-labeled peptide multimer functions as phage-mimic for high affinity, specific targeting of colonic adenomas in\u00a0vivo","volume":"76","author":"Joshi","year":"2012","journal-title":"Gastrointest Endosc"},{"key":"10.1053\/j.gastro.2016.12.009_bib27","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1399-3011.1990.tb00939.x","article-title":"Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids","volume":"35","author":"Fields","year":"1990","journal-title":"Int J Pept Protein Res"},{"key":"10.1053\/j.gastro.2016.12.009_bib28","doi-asserted-by":"crossref","first-page":"8103","DOI":"10.1364\/AO.37.008103","article-title":"Mathematical model of fluorescence endoscopic image formation","volume":"37","author":"Wang","year":"1998","journal-title":"Appl Opt"},{"key":"10.1053\/j.gastro.2016.12.009_bib29","first-page":"285","article-title":"A\u00a0threshold selection method from gray-level histograms","volume":"11","author":"Otsu","year":"1975","journal-title":"Automatica"},{"key":"10.1053\/j.gastro.2016.12.009_bib30","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1002\/pmic.200300680","article-title":"RELIC\u2014a bioinformatics server for combinatorial peptide analysis and identification of protein-ligand interaction sites","volume":"4","author":"Mandava","year":"2004","journal-title":"Proteomics"},{"key":"10.1053\/j.gastro.2016.12.009_bib31","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1016\/j.gie.2011.08.008","article-title":"A\u00a0morphologic analysis of sessile serrated polyps observed during routine colonoscopy (with video)","volume":"74","author":"Tadepalli","year":"2011","journal-title":"Gastrointest Endosc"},{"key":"10.1053\/j.gastro.2016.12.009_bib32","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1053\/j.gastro.2016.07.010","article-title":"Clinical and molecular characteristics of post-colonoscopy colorectal cancer: a population-based study","volume":"151","author":"Stoffel","year":"2016","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2016.12.009_bib33","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1053\/j.gastro.2010.01.009","article-title":"Molecular imaging in gastrointestinal endoscopy","volume":"138","author":"Goetz","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2016.12.009_bib34","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1038\/nm1692","article-title":"Detection of colonic dysplasia in\u00a0vivo using a targeted heptapeptide and confocal microendoscopy","volume":"14","author":"Hsiung","year":"2008","journal-title":"Nat Med"},{"key":"10.1053\/j.gastro.2016.12.009_bib35","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1016\/j.gie.2012.12.018","article-title":"Endoscopic features of sessile serrated adenomas: validation by international experts using high-resolution white-light endoscopy and narrow-band imaging","volume":"77","author":"Hazewinkel","year":"2013","journal-title":"Gastrointest Endosc"},{"key":"10.1053\/j.gastro.2016.12.009_bib36","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1111\/den.12540","article-title":"Sessile serrated adenoma\/polyp with cytological dysplasia diagnosed accurately by magnifying chromoendoscopy","volume":"28","author":"Murakami","year":"2016","journal-title":"Dig Endosc"},{"key":"10.1053\/j.gastro.2016.12.009_bib37","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.gie.2014.12.037","article-title":"Investigating endoscopic features of sessile serrated adenomas\/polyps by using narrow-band imaging with optical magnification","volume":"82","author":"Yamada","year":"2015","journal-title":"Gastrointest Endosc"},{"key":"10.1053\/j.gastro.2016.12.009_bib38","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1111\/jgh.12688","article-title":"Diagnostic features of sessile serrated adenoma\/polyps on magnifying narrow band imaging: a prospective study of diagnostic accuracy","volume":"30","author":"Yamashina","year":"2015","journal-title":"J\u00a0Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2016.12.009_bib39","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/j.gie.2009.03.1172","article-title":"Hyperplastic polyposis syndrome: a pilot study for the differentiation of polyps by using high-resolution endoscopy, autofluorescence imaging, and narrow-band imaging","volume":"70","author":"Boparai","year":"2009","journal-title":"Gastrointest Endosc"},{"key":"10.1053\/j.gastro.2016.12.009_bib40","doi-asserted-by":"crossref","first-page":"5889","DOI":"10.1158\/0008-5472.CAN-07-0245","article-title":"A\u00a0peptide selected by biopanning identifies the integrin \u03b1v\u03b26 as a prognostic biomarker for nonsmall cell lung cancer","volume":"67","author":"Elayadi","year":"2007","journal-title":"Cancer Res"},{"key":"10.1053\/j.gastro.2016.12.009_bib41","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.gie.2014.12.009","article-title":"SCENIC Guideline Development Panel. SCENIC international consensus statement on surveillance and management of dysplasia in inflammatory bowel disease","volume":"81","author":"Laine","year":"2015","journal-title":"Gastrointest Endosc"},{"key":"10.1053\/j.gastro.2016.12.009_bib42","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1053\/j.gastro.2012.08.053","article-title":"Multispectral endoscopic imaging of colorectal dysplasia in\u00a0vivo","volume":"143","author":"Joshi","year":"2012","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2016.12.009_bib43","article-title":"Fecal immunochemical test detects sessile serrated adenomas and polyps with a low level of sensitivity","author":"Chang","year":"2016","journal-title":"Clin Gastroenterol Hepatol"}],"container-title":["Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508516355202?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508516355202?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T15:13:23Z","timestamp":1758035603000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016508516355202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":43,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,4]]}},"alternative-id":["S0016508516355202"],"URL":"https:\/\/doi.org\/10.1053\/j.gastro.2016.12.009","relation":{},"ISSN":["0016-5085"],"issn-type":[{"value":"0016-5085","type":"print"}],"subject":[],"published":{"date-parts":[[2017,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Detection of Sessile Serrated Adenomas in the Proximal Colon Using Wide-Field Fluorescence Endoscopy","name":"articletitle","label":"Article Title"},{"value":"Gastroenterology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.gastro.2016.12.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 by the AGA Institute","name":"copyright","label":"Copyright"}]}}