{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T21:34:28Z","timestamp":1792704868909,"version":"4.5.0"},"reference-count":49,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,12,18]],"date-time":"2017-12-18T00:00:00Z","timestamp":1513555200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["SFB633"],"award-info":[{"award-number":["SFB633"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["316682"],"award-info":[{"award-number":["316682"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011102","name":"Seventh Framework Programme","doi-asserted-by":"publisher","award":["SFB633"],"award-info":[{"award-number":["SFB633"]}],"id":[{"id":"10.13039\/100011102","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011102","name":"Seventh Framework Programme","doi-asserted-by":"publisher","award":["316682"],"award-info":[{"award-number":["316682"]}],"id":[{"id":"10.13039\/100011102","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017268","name":"Berlin Institute of Health","doi-asserted-by":"publisher","award":["SFB633"],"award-info":[{"award-number":["SFB633"]}],"id":[{"id":"10.13039\/501100017268","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017268","name":"Berlin Institute of Health","doi-asserted-by":"publisher","award":["316682"],"award-info":[{"award-number":["316682"]}],"id":[{"id":"10.13039\/501100017268","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011264","name":"FP7 People: Marie-Curie Actions","doi-asserted-by":"publisher","award":["SFB633"],"award-info":[{"award-number":["SFB633"]}],"id":[{"id":"10.13039\/100011264","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011264","name":"FP7 People: Marie-Curie Actions","doi-asserted-by":"publisher","award":["316682"],"award-info":[{"award-number":["316682"]}],"id":[{"id":"10.13039\/100011264","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000783","name":"Research Executive Agency","doi-asserted-by":"publisher","award":["SFB633"],"award-info":[{"award-number":["SFB633"]}],"id":[{"id":"10.13039\/501100000783","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000783","name":"Research Executive Agency","doi-asserted-by":"publisher","award":["316682"],"award-info":[{"award-number":["316682"]}],"id":[{"id":"10.13039\/501100000783","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","gastrojournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastroenterology"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1053\/j.gastro.2017.12.008","type":"journal-article","created":{"date-parts":[[2017,12,19]],"date-time":"2017-12-19T13:00:34Z","timestamp":1513688434000},"page":"1391-1404.e9","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":119,"title":["Helicobacter pylori Depletes Cholesterol in Gastric Glands to Prevent Interferon Gamma Signaling and Escape the Inflammatory Response"],"prefix":"10.1053","volume":"154","author":[{"given":"Pau","family":"Morey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lennart","family":"Pfannkuch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ervinna","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Boccellato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Sigal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aki","family":"Imai-Matsushima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Dyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Koch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-Joachim","family":"Mollenkopf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8586-6417","authenticated-orcid":false,"given":"Philipp","family":"Schlaermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6120-8679","authenticated-orcid":false,"given":"Thomas F.","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/j.gastro.2017.12.008_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2011\/340157","article-title":"The human gastric pathogen helicobacter pylori and its association with gastric cancer and ulcer disease","volume":"2011","author":"Bauer","year":"2011","journal-title":"Ulcers"},{"key":"10.1053\/j.gastro.2017.12.008_bib2","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1053\/j.gastro.2015.02.049","article-title":"Helicobacter pylori activates and expands Lgr5(+) stem cells through\u00a0direct colonization of the gastric glands","volume":"148","author":"Sigal","year":"2015","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2017.12.008_bib3","doi-asserted-by":"crossref","first-page":"2384","DOI":"10.1016\/j.celrep.2017.08.039","article-title":"ALPK1- and TIFA-dependent innate immune response triggered by the helicobacter pylori type IV secretion system","volume":"20","author":"Zimmermann","year":"2017","journal-title":"Cell Rep"},{"key":"10.1053\/j.gastro.2017.12.008_bib4","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/S0016-5085(98)70531-1","article-title":"Lymphocytes in the human gastric mucosa during Helicobacter pylori have a T helper cell 1 phenotype","volume":"114","author":"Bamford","year":"1998","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2017.12.008_bib5","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/nrmicro3016","article-title":"Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori","volume":"11","author":"Salama","year":"2013","journal-title":"Nat Rev Microbiol"},{"key":"10.1053\/j.gastro.2017.12.008_bib6","doi-asserted-by":"crossref","first-page":"7085","DOI":"10.4049\/jimmunol.0803293","article-title":"The CD4+ T cell-mediated IFN-gamma response to Helicobacter infection is essential for clearance and determines gastric cancer risk","volume":"182","author":"Sayi","year":"2009","journal-title":"J\u00a0Immunol"},{"key":"10.1053\/j.gastro.2017.12.008_bib7","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1172\/JCI39481","article-title":"NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway","volume":"120","author":"Watanabe","year":"2010","journal-title":"J\u00a0Clin Invest"},{"key":"10.1053\/j.gastro.2017.12.008_bib8","doi-asserted-by":"crossref","first-page":"56","DOI":"10.3389\/fimmu.2012.00056","article-title":"IL-23 Contributes to control of chronic Helicobacter pylori infection and the development of T helper responses in a mouse model","volume":"3","author":"Horvath","year":"2012","journal-title":"Front Immunol"},{"key":"10.1053\/j.gastro.2017.12.008_bib9","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1136\/gutjnl-2014-307020","article-title":"A\u00a0pro-inflammatory role for Th22 cells in Helicobacter pylori-associated gastritis","volume":"64","author":"Zhuang","year":"2015","journal-title":"Gut"},{"key":"10.1053\/j.gastro.2017.12.008_bib10","doi-asserted-by":"crossref","first-page":"2357","DOI":"10.1126\/science.288.5475.2357","article-title":"Cross talk between interferon-gamma and -alpha\/beta signaling components in caveolar membrane domains","volume":"288","author":"Takaoka","year":"2000","journal-title":"Science"},{"key":"10.1053\/j.gastro.2017.12.008_bib11","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1016\/j.cell.2016.07.003","article-title":"Glycosylation-dependent IFN-gammaR partitioning in lipid and actin nanodomains is critical for JAK activation","volume":"166","author":"Blouin","year":"2016","journal-title":"Cell"},{"key":"10.1053\/j.gastro.2017.12.008_bib12","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1038\/nri3581","article-title":"Regulation of type I interferon responses","volume":"14","author":"Ivashkiv","year":"2014","journal-title":"Nat Rev Immunol"},{"key":"10.1053\/j.gastro.2017.12.008_bib13","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1038\/nm1720","article-title":"Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens","volume":"14","author":"Zheng","year":"2008","journal-title":"Nat Med"},{"key":"10.1053\/j.gastro.2017.12.008_bib14","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.chom.2012.04.013","article-title":"The Helicobacter pylori virulence effector CagA abrogates human beta-defensin 3 expression via inactivation of EGFR signaling","volume":"11","author":"Bauer","year":"2012","journal-title":"Cell Host Microbe"},{"key":"10.1053\/j.gastro.2017.12.008_bib15","doi-asserted-by":"crossref","first-page":"e73867","DOI":"10.1371\/journal.pone.0073867","article-title":"Gastric antimicrobial peptides fail to eradicate Helicobacter pylori infection due to selective induction and resistance","volume":"8","author":"Nuding","year":"2013","journal-title":"PLoS One"},{"key":"10.1053\/j.gastro.2017.12.008_bib16","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1111\/j.1365-2249.2004.02543.x","article-title":"beta-Defensin-3 and -4 in intestinal epithelial cells display increased mRNA expression in ulcerative colitis","volume":"137","author":"Fahlgren","year":"2004","journal-title":"Clin Exp Immunol"},{"key":"10.1053\/j.gastro.2017.12.008_bib17","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/j.molimm.2004.11.001","article-title":"Correlation between beta-defensin expression and induction profiles in gingival keratinocytes","volume":"42","author":"Joly","year":"2005","journal-title":"Mol Immunol"},{"key":"10.1053\/j.gastro.2017.12.008_bib18","doi-asserted-by":"crossref","first-page":"e0148514","DOI":"10.1371\/journal.pone.0148514","article-title":"IL-17a and IL-22 induce expression of antimicrobials in gastrointestinal epithelial cells and may contribute to epithelial cell defense against Helicobacter pylori","volume":"11","author":"Dixon","year":"2016","journal-title":"PLoS One"},{"key":"10.1053\/j.gastro.2017.12.008_bib19","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1111\/hel.12000","article-title":"Differential expression of human beta defensin 2 and 3 in gastric mucosa of Helicobacter pylori-infected individuals","volume":"18","author":"Bauer","year":"2013","journal-title":"Helicobacter"},{"key":"10.1053\/j.gastro.2017.12.008_bib20","doi-asserted-by":"crossref","first-page":"27765","DOI":"10.1074\/jbc.M603345200","article-title":"Cloning of a cholesterol-alpha-glucosyltransferase from Helicobacter pylori","volume":"281","author":"Lebrun","year":"2006","journal-title":"J\u00a0Biol Chem"},{"key":"10.1053\/j.gastro.2017.12.008_bib21","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1111\/j.1365-2958.2011.07910.x","article-title":"Helicobacter pylori cholesteryl glucosides interfere with host membrane phase and affect type IV secretion system function during infection in AGS cells","volume":"83","author":"Wang","year":"2012","journal-title":"Mol Microbiol"},{"key":"10.1053\/j.gastro.2017.12.008_bib22","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1038\/nm1480","article-title":"Cholesterol glucosylation promotes immune evasion by Helicobacter pylori","volume":"12","author":"Wunder","year":"2006","journal-title":"Nat Med"},{"key":"10.1053\/j.gastro.2017.12.008_bib23","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1093\/infdis\/jir547","article-title":"Modulation of the CD4+ T-cell response by Helicobacter pylori depends on known virulence factors and bacterial cholesterol and cholesterol alpha-glucoside content","volume":"204","author":"Beigier-Bompadre","year":"2011","journal-title":"J\u00a0Infect Dis"},{"key":"10.1053\/j.gastro.2017.12.008_bib24","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.jmii.2014.05.011","article-title":"Cholesterol glucosylation by Helicobacter pylori delays internalization and arrests phagosome maturation in macrophages","volume":"49","author":"Du","year":"2016","journal-title":"J\u00a0Microbiol Immunol Infect"},{"key":"10.1053\/j.gastro.2017.12.008_bib25","doi-asserted-by":"crossref","first-page":"4149","DOI":"10.4049\/jimmunol.1400594","article-title":"Helicobacter pylori infection activates Src homology-2 domain-containing phosphatase 2 to suppress IFN-gamma signaling","volume":"193","author":"Wang","year":"2014","journal-title":"J\u00a0Immunol"},{"key":"10.1053\/j.gastro.2017.12.008_bib26","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.biochi.2015.04.005","article-title":"Orchestration of membrane receptor signaling by membrane lipids","volume":"113","author":"Arish","year":"2015","journal-title":"Biochimie"},{"key":"10.1053\/j.gastro.2017.12.008_bib27","doi-asserted-by":"crossref","first-page":"e1002229","DOI":"10.1371\/journal.ppat.1002229","article-title":"Restoration of IFNgammaR subunit assembly, IFNgamma signaling and parasite clearance in Leishmania donovani infected macrophages: role of membrane cholesterol","volume":"7","author":"Sen","year":"2011","journal-title":"PLoS Pathog"},{"key":"10.1053\/j.gastro.2017.12.008_bib28","doi-asserted-by":"crossref","first-page":"12067","DOI":"10.1074\/jbc.M200018200","article-title":"Cytokine signaling: STATS in plasma membrane rafts","volume":"277","author":"Sehgal","year":"2002","journal-title":"J\u00a0Biol Chem"},{"key":"10.1053\/j.gastro.2017.12.008_bib29","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1002\/emmm.201201773","article-title":"Antimicrobial peptides and gut microbiota in homeostasis and pathology","volume":"5","author":"Ostaff","year":"2013","journal-title":"EMBO Mol Med"},{"key":"10.1053\/j.gastro.2017.12.008_bib30","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1136\/gutjnl-2014-307949","article-title":"A\u00a0novel human gastric primary cell culture system for modelling Helicobacter pylori infection in\u00a0vitro","volume":"65","author":"Schlaermann","year":"2016","journal-title":"Gut"},{"key":"10.1053\/j.gastro.2017.12.008_bib31","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1053\/j.gastro.2014.09.042","article-title":"In\u00a0vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection","volume":"148","author":"Bartfeld","year":"2015","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2017.12.008_bib32","article-title":"Polarised epithelial monolayers of the gastric mucosa reveal insights into mucosal homeostasis and defence against infection","author":"Boccellato","year":"2018","journal-title":"Gut"},{"key":"10.1053\/j.gastro.2017.12.008_bib33","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1128\/IAI.00228-06","article-title":"Chronic exposure to Helicobacter pylori impairs dendritic cell function and inhibits Th1 development","volume":"75","author":"Mitchell","year":"2007","journal-title":"Infect Immun"},{"key":"10.1053\/j.gastro.2017.12.008_bib34","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1136\/gut.2003.029736","article-title":"Cytokine gene polymorphisms influence mucosal cytokine expression, gastric inflammation, and host specific colonisation during Helicobacter pylori infection","volume":"53","author":"Rad","year":"2004","journal-title":"Gut"},{"key":"10.1053\/j.gastro.2017.12.008_bib35","doi-asserted-by":"crossref","first-page":"2595","DOI":"10.4049\/jimmunol.172.4.2595","article-title":"Inflammatory gene profiles in gastric mucosa during Helicobacter pylori infection in humans","volume":"172","author":"Wen","year":"2004","journal-title":"J\u00a0Immunol"},{"key":"10.1053\/j.gastro.2017.12.008_bib36","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1126\/science.1086871","article-title":"Helicobacter pylori vacuolating cytotoxin inhibits T lymphocyte activation","volume":"301","author":"Gebert","year":"2003","journal-title":"Science"},{"key":"10.1053\/j.gastro.2017.12.008_bib37","doi-asserted-by":"crossref","first-page":"3047","DOI":"10.1073\/pnas.1211248110","article-title":"Helicobacter pylori gamma-glutamyl transpeptidase and vacuolating cytotoxin promote gastric persistence and immune tolerance","volume":"110","author":"Oertli","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"Suppl 1","key":"10.1053\/j.gastro.2017.12.008_bib38","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/hel.12073","article-title":"Inflammation, immunity, vaccines for Helicobacter pylori infection","volume":"18","author":"Koch","year":"2013","journal-title":"Helicobacter"},{"key":"10.1053\/j.gastro.2017.12.008_bib39","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.01705-16","article-title":"Spatial and temporal shifts in bacterial biogeography and gland occupation during the development of a chronic infection","volume":"7","author":"Keilberg","year":"2016","journal-title":"MBio"},{"key":"10.1053\/j.gastro.2017.12.008_bib40","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1016\/j.vaccine.2011.12.111","article-title":"Mucosal vaccination increases local chemokine production attracting immune cells to the stomach mucosa of Helicobacter pylori infected mice","volume":"30","author":"Flach","year":"2012","journal-title":"Vaccine"},{"key":"10.1053\/j.gastro.2017.12.008_bib41","doi-asserted-by":"crossref","first-page":"2277","DOI":"10.1084\/jem.188.12.2277","article-title":"Immunization of mice with urease vaccine affords protection against Helicobacter pylori infection in the absence of antibodies and is mediated by MHC class II-restricted responses","volume":"188","author":"Ermak","year":"1998","journal-title":"J\u00a0Exp Med"},{"key":"10.1053\/j.gastro.2017.12.008_bib42","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1126\/science.1099250","article-title":"Natural antibiotic function of a human gastric mucin against Helicobacter pylori infection","volume":"305","author":"Kawakubo","year":"2004","journal-title":"Science"},{"key":"10.1053\/j.gastro.2017.12.008_bib43","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1053\/j.gastro.2005.12.038","article-title":"Influence of EPIYA-repeat polymorphism on the phosphorylation-dependent biological activity of Helicobacter pylori CagA","volume":"130","author":"Naito","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2017.12.008_bib44","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.chom.2007.09.003","article-title":"Cholesterol manipulation by West Nile virus perturbs the cellular\u00a0immune response","volume":"2","author":"Mackenzie","year":"2007","journal-title":"Cell Host Microbe"},{"key":"10.1053\/j.gastro.2017.12.008_bib45","doi-asserted-by":"crossref","first-page":"51125","DOI":"10.1074\/jbc.M304332200","article-title":"Cholesterol depletion results in site-specific increases in epidermal growth factor receptor phosphorylation due to membrane level effects. Studies with cholesterol enantiomers","volume":"278","author":"Westover","year":"2003","journal-title":"J\u00a0Biol Chem"},{"key":"10.1053\/j.gastro.2017.12.008_bib46","doi-asserted-by":"crossref","first-page":"3509","DOI":"10.1242\/jcs.006916","article-title":"Cholesterol suppresses cellular TGF-beta responsiveness: implications in atherogenesis","volume":"120","author":"Chen","year":"2007","journal-title":"J\u00a0Cell Sci"},{"key":"10.1053\/j.gastro.2017.12.008_bib47","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.ydbio.2016.09.014","article-title":"Modeling infectious diseases and host-microbe interactions in gastrointestinal organoids","volume":"420","author":"Bartfeld","year":"2016","journal-title":"Dev Biol"},{"key":"10.1053\/j.gastro.2017.12.008_bib48","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1016\/j.ajpath.2012.08.017","article-title":"Transgenic expression of interferon-gamma in mouse stomach leads to inflammation, metaplasia, and dysplasia","volume":"181","author":"Syu","year":"2012","journal-title":"Am J Pathol"},{"key":"10.1053\/j.gastro.2017.12.008_bib49","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1007\/s10620-008-0391-y","article-title":"The relationship between updated Sydney System score and LDL cholesterol levels in patients infected with Helicobacter pylori","volume":"54","author":"Kucukazman","year":"2009","journal-title":"Dig Dis Sci"}],"container-title":["Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508517367124?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508517367124?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T15:18:00Z","timestamp":1758035880000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016508517367124"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":49,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["S0016508517367124"],"URL":"https:\/\/doi.org\/10.1053\/j.gastro.2017.12.008","relation":{},"ISSN":["0016-5085"],"issn-type":[{"value":"0016-5085","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Helicobacter pylori Depletes Cholesterol in Gastric Glands to Prevent Interferon Gamma Signaling and Escape the Inflammatory Response","name":"articletitle","label":"Article Title"},{"value":"Gastroenterology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.gastro.2017.12.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 by the AGA Institute. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}