{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T15:57:42Z","timestamp":1758038262015,"version":"3.44.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","gastrojournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastroenterology"],"published-print":{"date-parts":[[2020,6]]},"DOI":"10.1053\/j.gastro.2020.03.068","type":"journal-article","created":{"date-parts":[[2020,4,2]],"date-time":"2020-04-02T19:23:45Z","timestamp":1585855425000},"page":"2043-2045","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Inside the Mind of a Cereal Killer: New Insights Into the Effect of Celiac Disease on Central Nervous Systems Function"],"prefix":"10.1053","volume":"158","author":[{"given":"Tobias L.","family":"Freitag","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel A.","family":"Leffler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1053\/j.gastro.2020.03.068_bib1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0022-510X(82)90076-4","article-title":"Degeneration of the central nervous system associated with celiac disease","volume":"53","author":"Kinney","year":"1982","journal-title":"J\u00a0Neurol Sci"},{"key":"10.1053\/j.gastro.2020.03.068_bib2","first-page":"1095","article-title":"A\u00a0syndrome of nontropical sprue with an unusual neurologic and psychiatric picture","volume":"46","author":"Kant","year":"1947","journal-title":"Wis Med J"},{"key":"10.1053\/j.gastro.2020.03.068_bib3","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1053\/j.gastro.2020.02.028","article-title":"Cognitive deficit and white matter changes in persons with celiac disease: a population-based study","volume":"158","author":"Croall","year":"2020","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2020.03.068_bib4","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1177\/2050640614560786","article-title":"Psychological morbidity of celiac disease: a review of the literature","volume":"3","author":"Zingone","year":"2015","journal-title":"United European Gastroenterol J"},{"key":"10.1053\/j.gastro.2020.03.068_bib5","doi-asserted-by":"crossref","first-page":"2654","DOI":"10.1056\/NEJMra1500587","volume":"373","author":"Scammell","year":"2015","journal-title":"Narcolepsy. N Engl J Med"},{"key":"10.1053\/j.gastro.2020.03.068_bib6","doi-asserted-by":"crossref","first-page":"E12323","DOI":"10.1073\/pnas.1818150116","article-title":"Autoimmunity to hypocretin and molecular mimicry to flu in type 1 narcolepsy","volume":"115","author":"Luo","year":"2018","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1053\/j.gastro.2020.03.068_bib7","article-title":"Metagenomics of the faecal virome indicate a cumulative effect of enterovirus and gluten amount on the risk of coeliac disease autoimmunity in genetically at risk children: the TEDDY study","author":"Lindfors","year":"2019","journal-title":"Gut"},{"key":"10.1053\/j.gastro.2020.03.068_bib8","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1126\/science.aah5298","article-title":"Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease","volume":"356","author":"Bouziat","year":"2017","journal-title":"Science"},{"key":"10.1053\/j.gastro.2020.03.068_bib9","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0114361","article-title":"Antigenic differences between AS03 adjuvanted influenza A (H1N1) pandemic vaccines: implications for pandemrix-associated narcolepsy risk","volume":"9","author":"Vaarala","year":"2014","journal-title":"PLoS One"},{"key":"10.1053\/j.gastro.2020.03.068_bib10","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1172\/JCI41366","article-title":"Elevated Tribbles homolog 2-specific antibody levels in narcolepsy patients","volume":"120","author":"Cvetkovic-Lopes","year":"2010","journal-title":"J\u00a0Clin Invest"},{"key":"10.1053\/j.gastro.2020.03.068_bib11","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1038\/s41582-019-0226-9","article-title":"Narcolepsy - clinical spectrum, aetiopathophysiology, diagnosis and treatment","volume":"15","author":"Bassetti","year":"2019","journal-title":"Nat Rev Neurol"},{"key":"10.1053\/j.gastro.2020.03.068_bib12","doi-asserted-by":"crossref","first-page":"101963","DOI":"10.1016\/j.nicl.2019.101963","article-title":"Widespread white matter connectivity abnormalities in narcolepsy type 1: A diffusion tensor imaging study","volume":"24","author":"Gool","year":"2019","journal-title":"Neuroimage Clin"},{"key":"10.1053\/j.gastro.2020.03.068_bib13","doi-asserted-by":"crossref","DOI":"10.3390\/nu11020380","article-title":"Neurological manifestations of neuropathy and ataxia in celiac disease: a systematic review","volume":"11","author":"Mearns","year":"2019","journal-title":"Nutrients"},{"key":"10.1053\/j.gastro.2020.03.068_bib14","doi-asserted-by":"crossref","first-page":"106393","DOI":"10.1016\/j.yebeh.2019.06.036","article-title":"Neuropsychiatric manifestations in celiac disease","volume":"99","author":"Trovato","year":"2019","journal-title":"Epilepsy Behav"},{"key":"10.1053\/j.gastro.2020.03.068_bib15","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1016\/S0140-6736(98)05342-2","article-title":"Clinical, radiological, neurophysiological, and neuropathological characteristics of gluten ataxia","volume":"352","author":"Hadjivassiliou","year":"1998","journal-title":"Lancet"},{"key":"10.1053\/j.gastro.2020.03.068_bib16","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/S1474-4422(09)70290-X","article-title":"Gluten sensitivity: from gut to brain","volume":"9","author":"Hadjivassiliou","year":"2010","journal-title":"Lancet Neurol"},{"key":"10.1053\/j.gastro.2020.03.068_bib17","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1111\/exd.13449","article-title":"Transglutaminases in autoimmune and inherited skin diseases: The phenomena of epitope spreading and functional compensation","volume":"27","author":"Karpati","year":"2018","journal-title":"Exp Dermatol"},{"key":"10.1053\/j.gastro.2020.03.068_bib18","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1097\/01.mcp.0000183062.98665.6b","article-title":"Cytokines and normal sleep","volume":"11","author":"Kapsimalis","year":"2005","journal-title":"Curr Opin Pulm Med"},{"key":"10.1053\/j.gastro.2020.03.068_bib19","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/j.psyneuen.2011.04.003","article-title":"Poorer self-rated health is associated with elevated inflammatory markers among older adults","volume":"36","author":"Christian","year":"2011","journal-title":"Psychoneuroendocrinology"},{"key":"10.1053\/j.gastro.2020.03.068_bib20","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1111\/cei.13369","article-title":"Serum cytokines elevated during gluten-mediated cytokine release in coeliac disease","volume":"199","author":"Goel","year":"2020","journal-title":"Clin Exp Immunol"},{"key":"10.1053\/j.gastro.2020.03.068_bib21","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/j.1572-0241.1998.00413.x","article-title":"Pre- and post-treatment serum levels of cytokines IL-1beta, IL-6, and IL-1 receptor antagonist in celiac disease. Are they related to the associated osteopenia?","volume":"93","author":"Fornari","year":"1998","journal-title":"Am J Gastroenterol"}],"container-title":["Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508520304510?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508520304510?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T15:22:57Z","timestamp":1758036177000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016508520304510"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6]]},"references-count":21,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["S0016508520304510"],"URL":"https:\/\/doi.org\/10.1053\/j.gastro.2020.03.068","relation":{},"ISSN":["0016-5085"],"issn-type":[{"type":"print","value":"0016-5085"}],"subject":[],"published":{"date-parts":[[2020,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inside the Mind of a Cereal Killer: New Insights Into the Effect of Celiac Disease on Central Nervous Systems Function","name":"articletitle","label":"Article Title"},{"value":"Gastroenterology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.gastro.2020.03.068","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1053\/j.gastro.2020.02.028","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 by the AGA Institute","name":"copyright","label":"Copyright"}]}}