{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T07:56:18Z","timestamp":1791618978165,"version":"4.3.4"},"reference-count":53,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100005192","name":"Danmarks Tekniske Universitet","doi-asserted-by":"publisher","award":["NNF10CC1016517"],"award-info":[{"award-number":["NNF10CC1016517"]}],"id":[{"id":"10.13039\/501100005192","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005192","name":"Danmarks Tekniske Universitet","doi-asserted-by":"publisher","award":["R35 GM119850"],"award-info":[{"award-number":["R35 GM119850"]}],"id":[{"id":"10.13039\/501100005192","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009708","name":"Novo Nordisk Fonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009708","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","gastrojournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastroenterology"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1053\/j.gastro.2020.07.035","type":"journal-article","created":{"date-parts":[[2020,7,23]],"date-time":"2020-07-23T11:25:23Z","timestamp":1595503523000},"page":"1778-1792.e13","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":50,"title":["Increased Production of LIGHT by T Cells in Eosinophilic Esophagitis Promotes Differentiation of Esophageal Fibroblasts Toward an Inflammatory Phenotype"],"prefix":"10.1053","volume":"159","author":[{"given":"Mario C.","family":"Manresa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6514-5612","authenticated-orcid":false,"given":"Austin W.T.","family":"Chiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard C.","family":"Kurten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranjan","family":"Dohil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0075-7399","authenticated-orcid":false,"given":"Howard","family":"Brickner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas","family":"Dohil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rana","family":"Herro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Praveen","family":"Akuthota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7700-3654","authenticated-orcid":false,"given":"Nathan E.","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Croft","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seema S.","family":"Aceves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/j.gastro.2020.07.035_bib1","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1038\/ajg.2014.316","article-title":"Health-care utilization, costs, and the burden of disease related to eosinophilic esophagitis in the United States","volume":"110","author":"Jensen","year":"2015","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2020.07.035_bib2","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.anai.2014.01.023","article-title":"Eosinophilic esophagitis","volume":"112","author":"Merves","year":"2014","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1053\/j.gastro.2020.07.035_bib3","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1159\/000357004","article-title":"Remodeling and fibrosis in chronic eosinophil inflammation","volume":"32","author":"Aceves","year":"2014","journal-title":"Dig Dis"},{"key":"10.1053\/j.gastro.2020.07.035_bib4","doi-asserted-by":"crossref","first-page":"128","DOI":"10.3389\/fmed.2017.00128","article-title":"Tissue remodeling in chronic eosinophilic esophageal inflammation: parallels in asthma and therapeutic perspectives","volume":"4","author":"Nhu","year":"2017","journal-title":"Front Med (Lausanne)"},{"key":"10.1053\/j.gastro.2020.07.035_bib5","doi-asserted-by":"crossref","first-page":"R1369","DOI":"10.1152\/ajpregu.00349.2014","article-title":"Hypoxia-sensitive pathways in inflammation-driven fibrosis","volume":"307","author":"Manresa","year":"2014","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1053\/j.gastro.2020.07.035_bib6","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1002\/JLB.5MR1017-395R","article-title":"Understanding fibrosis in eosinophilic esophagitis: are we there yet?","volume":"104","author":"Armbruster-Lee","year":"2018","journal-title":"J\u00a0Leukoc Biol"},{"key":"10.1053\/j.gastro.2020.07.035_bib7","doi-asserted-by":"crossref","first-page":"Ab246","DOI":"10.1016\/j.jaci.2011.12.055","article-title":"Dietary therapy and topical corticosteroids can reverse esophageal fibrosis in patients with eosinophilic esophagitis","volume":"129","author":"Lieberman","year":"2012","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1053\/j.gastro.2020.07.035_bib8","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.jaci.2018.10.067","article-title":"Fibrostenotic eosinophilic esophagitis might reflect epithelial lysyl oxidase induction by fibroblast-derived TNF-\u03b1","volume":"144","author":"Kasagi","year":"2019","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1053\/j.gastro.2020.07.035_bib9","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.cell.2018.08.067","article-title":"Structural remodeling of the human colonic mesenchyme in inflammatory bowel disease","volume":"175","author":"Kinchen","year":"2018","journal-title":"Cell"},{"key":"10.1053\/j.gastro.2020.07.035_bib10","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1038\/s41590-019-0378-1","article-title":"Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry","volume":"20","author":"Zhang","year":"2019","journal-title":"Nat Immunol"},{"key":"10.1053\/j.gastro.2020.07.035_bib11","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1038\/s41467-018-08247-x","article-title":"Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds","volume":"10","author":"Guerrero-Juarez","year":"2019","journal-title":"Nat Commun"},{"key":"10.1053\/j.gastro.2020.07.035_bib12","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1038\/s41385-019-0214-9","article-title":"TGF\u03b21 single-nucleotide polymorphism C-509T alters mucosal cell function in pediatric eosinophilic esophagitis","volume":"13","author":"Duong","year":"2019","journal-title":"Mucosal Immunol"},{"issue":"12","key":"10.1053\/j.gastro.2020.07.035_bib13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0144651","article-title":"The TGF\u03b21 promoter SNP C-509T and food sensitization promote esophageal remodeling in pediatric eosinophilic esophagitis","volume":"10","author":"Rawson","year":"2015","journal-title":"PLoS One"},{"key":"10.1053\/j.gastro.2020.07.035_bib14","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.jaci.2016.02.028","article-title":"TGF-\u03b21-induced PAI-1 contributes to a profibrotic network in patients with eosinophilic esophagitis","volume":"138","author":"Rawson","year":"2016","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1053\/j.gastro.2020.07.035_bib15","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1016\/j.jaci.2014.04.004","article-title":"TGF-\u03b21-induced phospholamban expression alters esophageal smooth muscle cell contraction in patients with eosinophilic esophagitis","volume":"134","author":"Beppu","year":"2014","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1053\/j.gastro.2020.07.035_bib16","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1097\/MPG.0000000000001100","article-title":"Eosinophilic esophagitis-associated chemical and mechanical microenvironment shapes esophageal fibroblast behavior","volume":"63","author":"Muir","year":"2016","journal-title":"J\u00a0Pediatr Gastroenterol Nutr"},{"key":"10.1053\/j.gastro.2020.07.035_bib17","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1097\/MPG.0000000000000343","article-title":"Smad3-deficient mice have reduced esophageal fibrosis and angiogenesis in a model of egg-induced eosinophilic esophagitis","volume":"59","author":"Cho","year":"2014","journal-title":"J\u00a0Pediatr Gastroenterol Nutr"},{"issue":"195","key":"10.1053\/j.gastro.2020.07.035_bib18","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3006448","article-title":"TGF\u03b2 receptor mutations impose a strong predisposition for human allergic disease","volume":"5","author":"Frischmeyer-Guerrerio","year":"2013","journal-title":"Sci Transl Med"},{"key":"10.1053\/j.gastro.2020.07.035_bib19","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1038\/nm.2356","article-title":"The tumor necrosis factor family member LIGHT is a target for asthmatic airway remodeling","volume":"17","author":"Doherty","year":"2011","journal-title":"Nat Med"},{"key":"10.1053\/j.gastro.2020.07.035_bib20","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.jaci.2014.12.1936","article-title":"Tumor necrosis factor superfamily 14 (LIGHT) controls thymic stromal lymphopoietin to drive pulmonary fibrosis","volume":"136","author":"Herro","year":"2015","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1053\/j.gastro.2020.07.035_bib21","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1038\/jid.2015.110","article-title":"The tumor necrosis factor superfamily molecule LIGHT promotes keratinocyte activity and skin fibrosis","volume":"135","author":"Herro","year":"2015","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1053\/j.gastro.2020.07.035_bib22","doi-asserted-by":"crossref","first-page":"576","DOI":"10.3389\/fimmu.2018.00576","article-title":"TNFSF14 (LIGHT) exhibits inflammatory activities in lung fibroblasts complementary to IL-13 and TGF-\u03b2","volume":"9","author":"Antunes","year":"2018","journal-title":"Front Immunol"},{"key":"10.1053\/j.gastro.2020.07.035_bib23","doi-asserted-by":"crossref","first-page":"251","DOI":"10.4049\/jimmunol.173.1.251","article-title":"LIGHT expression by mucosal T cells may regulate IFN-\u03b3 expression in the intestine","volume":"173","author":"Cohavy","year":"2004","journal-title":"J\u00a0Immunol"},{"key":"10.1053\/j.gastro.2020.07.035_bib24","doi-asserted-by":"crossref","first-page":"646","DOI":"10.4049\/jimmunol.174.2.646","article-title":"LIGHT is constitutively expressed on T and NK cells in the human gut and can be induced by CD2-mediated signaling","volume":"174","author":"Cohavy","year":"2005","journal-title":"J\u00a0Immunol"},{"key":"10.1053\/j.gastro.2020.07.035_bib25","doi-asserted-by":"crossref","first-page":"4105","DOI":"10.4049\/jimmunol.164.8.4105","article-title":"LIGHT, a TNF-like molecule, costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell response","volume":"164","author":"Tamada","year":"2000","journal-title":"J\u00a0Immunol"},{"key":"10.1053\/j.gastro.2020.07.035_bib26","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.ccell.2016.02.004","article-title":"Facilitating T cell infiltration in tumor microenvironment overcomes resistance to PD-L1 blockade","volume":"29","author":"Tang","year":"2016","journal-title":"Cancer Cell"},{"key":"10.1053\/j.gastro.2020.07.035_bib27","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1007\/s10620-013-2599-8","article-title":"T\u00a0cell co-stimulatory molecules: a co-conspirator in the pathogenesis of eosinophilic esophagitis?","volume":"58","author":"Zhang","year":"2013","journal-title":"Digest Dis Sci"},{"key":"10.1053\/j.gastro.2020.07.035_bib28","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1097\/MPG.0000000000000668","article-title":"MMPs-2 and -14 are elevated in eosinophilic esophagitis and reduced following topical corticosteroid therapy","volume":"61","author":"Beppu","year":"2015","journal-title":"J\u00a0Pediatr Gastroenterol Nutr"},{"key":"10.1053\/j.gastro.2020.07.035_bib29","doi-asserted-by":"crossref","first-page":"329","DOI":"10.4049\/jimmunol.1801668","article-title":"Human eosinophils express a distinct gene expression program in response to IL-3 compared with common \u03b2-chain cytokines IL-5 and GM-CSF","volume":"203","author":"Nelson","year":"2019","journal-title":"J\u00a0Immunol"},{"key":"10.1053\/j.gastro.2020.07.035_bib30","doi-asserted-by":"crossref","first-page":"2624","DOI":"10.3389\/fimmu.2018.02624","article-title":"Baseline gastrointestinal eosinophilia is common in oral immunotherapy subjects with IgE-mediated peanut allergy","volume":"9","author":"Wright","year":"2018","journal-title":"Front Immunol"},{"key":"10.1053\/j.gastro.2020.07.035_bib31","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1093\/bioinformatics\/btp120","article-title":"TopHat: discovering splice junctions with RNA-Seq","volume":"25","author":"Trapnell","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1053\/j.gastro.2020.07.035_bib32","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1093\/bioinformatics\/btr026","article-title":"Quality control and preprocessing of metagenomic datasets","volume":"27","author":"Schmieder","year":"2011","journal-title":"Bioinformatics"},{"key":"10.1053\/j.gastro.2020.07.035_bib33","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1093\/bioinformatics\/btp352","article-title":"The Sequence Alignment\/Map format and SAMtools","volume":"25","author":"Li","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1053\/j.gastro.2020.07.035_bib34","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1093\/bioinformatics\/btu638","article-title":"HTSeq\u2014a Python framework to work with high-throughput sequencing data","volume":"31","author":"Anders","year":"2015","journal-title":"Bioinformatics"},{"issue":"12","key":"10.1053\/j.gastro.2020.07.035_bib35","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol"},{"key":"10.1053\/j.gastro.2020.07.035_bib36","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J\u00a0R Stat Soc Series B Stat Methodol"},{"key":"10.1053\/j.gastro.2020.07.035_bib37","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.1172\/JCI125917","article-title":"Single-cell RNA sequencing identifies inflammatory tissue T cells in eosinophilic esophagitis","volume":"129","author":"Wen","year":"2019","journal-title":"J\u00a0Clin Invest"},{"key":"10.1053\/j.gastro.2020.07.035_bib38","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/j.jaci.2005.06.031","article-title":"Eosinophil-fibroblast interactions induce fibroblast IL-6 secretion and extracellular matrix gene expression: implications in fibrogenesis","volume":"116","author":"Gomes","year":"2005","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1053\/j.gastro.2020.07.035_bib39","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/S0016-5085(99)70447-6","article-title":"Regulation of ICAM-1\u2013mediated fibroblast\u2013T cell reciprocal interaction: implications for modulation of gut inflammation","volume":"117","author":"Musso","year":"1999","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2020.07.035_bib40","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1111\/j.1365-2567.2010.03307.x","article-title":"Stromal cells differentially regulate neutrophil and lymphocyte recruitment through the endothelium","volume":"131","author":"McGettrick","year":"2010","journal-title":"Immunology"},{"key":"10.1053\/j.gastro.2020.07.035_bib41","doi-asserted-by":"crossref","first-page":"5248","DOI":"10.1158\/0008-5472.CAN-15-0732","article-title":"Stromal fibroblasts induce CCL20 through IL6\/C\/EBP\u03b2 to support the recruitment of Th17 cells during cervical cancer progression","volume":"75","author":"Walch-R\u00fcckheim","year":"2015","journal-title":"Cancer Res"},{"issue":"1","key":"10.1053\/j.gastro.2020.07.035_bib42","doi-asserted-by":"crossref","first-page":"3172","DOI":"10.1038\/s41598-019-39553-z","article-title":"Cancer associated fibroblasts sculpt tumour microenvironment by recruiting monocytes and inducing immunosuppressive PD-1+ TAMs","volume":"9","author":"Gokyavuz","year":"2019","journal-title":"Sci Rep"},{"issue":"1","key":"10.1053\/j.gastro.2020.07.035_bib43","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1038\/s42003-020-0922-4","article-title":"Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming","volume":"3","author":"Sol\u00e9-Boldo","year":"2020","journal-title":"Commun Biol"},{"key":"10.1053\/j.gastro.2020.07.035_bib44","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1111\/all.13390","article-title":"Tumor necrosis factor family member LIGHT acts with IL-1\u03b2 and TGF-\u03b2 to promote airway remodeling during rhinovirus infection","volume":"73","author":"Mehta","year":"2018","journal-title":"Allergy"},{"key":"10.1053\/j.gastro.2020.07.035_bib45","doi-asserted-by":"crossref","first-page":"2429","DOI":"10.4049\/jimmunol.1500356","article-title":"The TNF family molecules LIGHT and lymphotoxin \u03b1\u03b2 induce a distinct steroid-resistant inflammatory phenotype in human lung epithelial cells","volume":"195","author":"Antunes","year":"2015","journal-title":"J\u00a0Immunol"},{"key":"10.1053\/j.gastro.2020.07.035_bib46","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1084\/jem.20170536","article-title":"LIGHT-HVEM signaling in keratinocytes controls development of dermatitis","volume":"215","author":"Herro","year":"2018","journal-title":"J\u00a0Exp Med"},{"key":"10.1053\/j.gastro.2020.07.035_bib47","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1016\/j.jaci.2010.08.050","article-title":"Mast cells infiltrate the esophageal smooth muscle in patients with eosinophilic esophagitis, express TGF\u03b21, and increase esophageal smooth muscle contraction","volume":"126","author":"Aceves","year":"2010","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1053\/j.gastro.2020.07.035_bib48","doi-asserted-by":"crossref","first-page":"6330","DOI":"10.4049\/jimmunol.167.11.6330","article-title":"Constitutive expression of LIGHT on T cells leads to lymphocyte activation, inflammation, and tissue destruction","volume":"167","author":"Shaikh","year":"2001","journal-title":"J\u00a0Immunol"},{"key":"10.1053\/j.gastro.2020.07.035_bib49","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1186\/2047-783X-14-4-147","article-title":"Proinflammatory and prothrombotic effects on human vascular endothelial cells of immune-cell-derived light","volume":"14","author":"Celik","year":"2009","journal-title":"Eur J Med Res"},{"issue":"52","key":"10.1053\/j.gastro.2020.07.035_bib50","doi-asserted-by":"crossref","first-page":"E5688","DOI":"10.1073\/pnas.1411072112","article-title":"Licensed human natural killer cells aid dendritic cell maturation via TNFSF14\/LIGHT","volume":"111","author":"Holmes","year":"2014","journal-title":"Proc Nat Acad Sci U S A"},{"key":"10.1053\/j.gastro.2020.07.035_bib51","doi-asserted-by":"crossref","first-page":"136463","DOI":"10.1155\/2014\/136463","article-title":"Effect of tumor necrosis factor family member LIGHT (TNFSF14) on the activation of basophils and eosinophils interacting with bronchial epithelial cells","volume":"2014","author":"Qiu","year":"2014","journal-title":"Mediators Inflamm"},{"key":"10.1053\/j.gastro.2020.07.035_bib52","doi-asserted-by":"crossref","first-page":"13696","DOI":"10.1038\/ncomms13696","article-title":"A\u00a0TNFRSF14-Fc\u03b5RI-mast cell pathway contributes to development of multiple features of asthma pathology in mice","volume":"7","author":"Sibilano","year":"2016","journal-title":"Nat Commun"},{"key":"10.1053\/j.gastro.2020.07.035_bib53","doi-asserted-by":"crossref","first-page":"36763","DOI":"10.1074\/jbc.M302686200","article-title":"Lymphocyte function-associated antigen-1-mediated T cell adhesion is impaired by low molecular weight phosphotyrosine phosphatase-dependent inhibition of FAK activity","volume":"278","author":"Giannoni","year":"2003","journal-title":"J\u00a0Biol Chem"}],"container-title":["Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508520349970?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508520349970?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T09:47:33Z","timestamp":1762163253000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016508520349970"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":53,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["S0016508520349970"],"URL":"https:\/\/doi.org\/10.1053\/j.gastro.2020.07.035","relation":{},"ISSN":["0016-5085"],"issn-type":[{"value":"0016-5085","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Increased Production of LIGHT by T Cells in Eosinophilic Esophagitis Promotes Differentiation of Esophageal Fibroblasts Toward an Inflammatory Phenotype","name":"articletitle","label":"Article Title"},{"value":"Gastroenterology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.gastro.2020.07.035","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 by the AGA Institute","name":"copyright","label":"Copyright"}]}}