{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T03:28:34Z","timestamp":1758079714718,"version":"3.44.0"},"reference-count":7,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U20A20346"],"award-info":[{"award-number":["U20A20346"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","gastrojournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastroenterology"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1053\/j.gastro.2023.09.044","type":"journal-article","created":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T02:01:48Z","timestamp":1696557708000},"page":"e1-e5","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Refractory Diarrhea and Gastric Adenocarcinoma, Just a Coincidence?"],"prefix":"10.1053","volume":"166","author":[{"given":"Shi-Yuan","family":"Lu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanyun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3457-2560","authenticated-orcid":false,"given":"Yan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1053\/j.gastro.2023.09.044_bib1","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/gim.2015.30","article-title":"Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology","volume":"17","author":"Richards","year":"2015","journal-title":"Genet Med"},{"key":"10.1053\/j.gastro.2023.09.044_bib2","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.jaci.2012.05.043","article-title":"LPS-responsive beige-like anchor (LRBA) gene mutation in a family with inflammatory bowel disease and combined immunodeficiency","volume":"130","author":"Alangari","year":"2012","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1053\/j.gastro.2023.09.044_bib3","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1111\/imr.12726","article-title":"Early-onset inflammatory bowel disease as a model disease to identify key regulators of immune homeostasis mechanisms","volume":"287","author":"Pazmandi","year":"2019","journal-title":"Immunol Rev"},{"key":"10.1053\/j.gastro.2023.09.044_bib4","doi-asserted-by":"crossref","first-page":"2379","DOI":"10.1016\/j.jaip.2019.04.011","article-title":"Clinical, immunologic, and molecular spectrum of patients with LPS-responsive beige-like anchor protein deficiency: a systematic review","volume":"7","author":"Habibi","year":"2019","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1053\/j.gastro.2023.09.044_bib5","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1016\/j.jaci.2019.12.896","article-title":"Long-term outcome of LRBA deficiency in 76 patients after various treatment modalities as evaluated by the immune deficiency and dysregulation activity (IDDA) score","volume":"145","author":"Tesch","year":"2020","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1053\/j.gastro.2023.09.044_bib6","doi-asserted-by":"crossref","first-page":"2790","DOI":"10.1016\/j.jaip.2019.06.011","article-title":"Abatacept as a long-term targeted therapy for LRBA deficiency","volume":"7","author":"Kiykim","year":"2019","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1053\/j.gastro.2023.09.044_bib7","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1016\/j.jaci.2023.08.004","article-title":"Therapeutic modalities and clinical outcomes in a large cohort with LRBA deficiency and CTLA4 insufficiency","volume":"152","author":"Taghizade","year":"2023","journal-title":"J\u00a0Allergy Clin Immunol"}],"container-title":["Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508523050795?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508523050795?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T15:44:42Z","timestamp":1758037482000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016508523050795"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":7,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["S0016508523050795"],"URL":"https:\/\/doi.org\/10.1053\/j.gastro.2023.09.044","relation":{},"ISSN":["0016-5085"],"issn-type":[{"type":"print","value":"0016-5085"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Refractory Diarrhea and Gastric Adenocarcinoma, Just a Coincidence?","name":"articletitle","label":"Article Title"},{"value":"Gastroenterology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.gastro.2023.09.044","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 by the AGA Institute.","name":"copyright","label":"Copyright"}]}}