{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T18:27:46Z","timestamp":1793212066582,"version":"4.5.0"},"reference-count":97,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["K23DK117058"],"award-info":[{"award-number":["K23DK117058"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["R03DK129631"],"award-info":[{"award-number":["R03DK129631"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1 TR002535"],"award-info":[{"award-number":["UL1 TR002535"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007028","name":"Leona M. and Harry B. Helmsley Charitable Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007028","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["K23DK127157"],"award-info":[{"award-number":["K23DK127157"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["K23DK129762-02"],"award-info":[{"award-number":["K23DK129762-02"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["R01 DK127171"],"award-info":[{"award-number":["R01 DK127171"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["R21DK127227"],"award-info":[{"award-number":["R21DK127227"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","gastrojournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastroenterology"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1053\/j.gastro.2023.10.015","type":"journal-article","created":{"date-parts":[[2023,12,19]],"date-time":"2023-12-19T04:02:28Z","timestamp":1702958548000},"page":"59-85","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":131,"title":["AGA Clinical Practice Guideline on the Management of Pouchitis and Inflammatory Pouch Disorders"],"prefix":"10.1053","volume":"166","author":[{"given":"Edward L.","family":"Barnes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manasi","family":"Agrawal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaurav","family":"Syal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwin N.","family":"Ananthakrishnan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin L.","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Haydek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elie S.","family":"Al Kazzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Eisenstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana G.","family":"Hashash","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahnaz S.","family":"Sultan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura E.","family":"Raffals","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siddharth","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/j.gastro.2023.10.015_bib1","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1016\/j.cgh.2020.06.035","article-title":"Incidence, risk factors, and outcomes of pouchitis and pouch-related complications in patients with ulcerative colitis","volume":"19","author":"Barnes","year":"2021","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2023.10.015_bib2","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1097\/MIB.0000000000001061","article-title":"Results at up to 30 years after ileal pouch-anal anastomosis for chronic ulcerative colitis","volume":"23","author":"Lightner","year":"2017","journal-title":"Inflamm Bowel Dis"},{"key":"10.1053\/j.gastro.2023.10.015_bib3","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1097\/MIB.0000000000001119","article-title":"Pouch-related symptoms and quality of life in patients with ileal pouch-anal anastomosis","volume":"23","author":"Barnes","year":"2017","journal-title":"Inflamm Bowel Dis"},{"key":"10.1053\/j.gastro.2023.10.015_bib4","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1136\/gutjnl-2021-326390","article-title":"Efficacy of biological therapies and small molecules in moderate to severe ulcerative colitis: systematic review and network meta-analysis","volume":"71","author":"Burr","year":"2022","journal-title":"Gut"},{"key":"10.1053\/j.gastro.2023.10.015_bib5","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S2468-1253(21)00377-0","article-title":"Efficacy and safety of biologics and small molecule drugs for patients with moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis","volume":"7","author":"Lasa","year":"2022","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2023.10.015_bib6","first-page":"1225","article-title":"Decreasing colectomy rate for ulcerative colitis in the United States between 2007 and 2016: a time trend analysis","volume":"26","author":"Barnes","year":"2020","journal-title":"Inflamm Bowel Dis"},{"key":"10.1053\/j.gastro.2023.10.015_bib7","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.cgh.2022.04.015","article-title":"Increasing incidence of pouchitis between 1996 and 2018: a population-based danish cohort study","volume":"21","author":"Barnes","year":"2023","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2023.10.015_bib8","doi-asserted-by":"crossref","first-page":"2908","DOI":"10.1016\/j.cgh.2021.09.037","article-title":"Patients with pouchitis demonstrate a significant cost burden in the first two years after ileal pouch-anal anastomosis","volume":"20","author":"Barnes","year":"2022","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2023.10.015_bib9","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1097\/SLA.0b013e31827d99a2","article-title":"Ileal pouch anal anastomosis: analysis of outcome and quality of life in 3707 patients","volume":"257","author":"Fazio","year":"2013","journal-title":"Ann Surg"},{"key":"10.1053\/j.gastro.2023.10.015_bib10","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1093\/ibd\/izz005","article-title":"The incidence and definition of Crohn's disease of the pouch: a systematic review and meta-analysis","volume":"25","author":"Barnes","year":"2019","journal-title":"Inflamm Bowel Dis"},{"key":"10.1053\/j.gastro.2023.10.015_bib11","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1097\/DCR.0000000000002663","article-title":"Development and validation of a symptom-based scoring system for bowel dysfunction after ileoanal pouch reconstruction: the ileoanal pouch syndrome severity score","volume":"66","author":"Cavallaro","year":"2023","journal-title":"Dis Colon Rectum"},{"key":"10.1053\/j.gastro.2023.10.015_bib12","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.cgh.2021.02.010","article-title":"Endoscopic phenotype of the J pouch in patients with inflammatory bowel disease: a new classification for pouch outcomes","volume":"20","author":"Akiyama","year":"2022","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2023.10.015_bib13","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1016\/j.cgh.2022.04.026","article-title":"Development of the endoscopic pouch score for assessment of inflammatory conditions of the pouch","volume":"21","author":"Barnes","year":"2023","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2023.10.015_bib14","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1056\/NEJMoa2208450","article-title":"Vedolizumab for the treatment of chronic pouchitis","volume":"388","author":"Travis","year":"2023","journal-title":"N\u00a0Engl J Med"},{"key":"10.1053\/j.gastro.2023.10.015_bib15","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1053\/j.gastro.2020.01.006","article-title":"AGA Clinical Practice Guidelines on the management of moderate to severe ulcerative colitis","volume":"158","author":"Feuerstein","year":"2020","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2023.10.015_bib16","doi-asserted-by":"crossref","first-page":"2496","DOI":"10.1053\/j.gastro.2021.04.022","article-title":"AGA Clinical Practice Guidelines on the medical management of moderate to severe luminal and perianal fistulizing Crohn's disease","volume":"160","author":"Feuerstein","year":"2021","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2023.10.015_bib17","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.cgh.2013.02.001","article-title":"The AGA Institute process for developing clinical practice guidelines part one: grading the evidence","volume":"11","author":"Sultan","year":"2013","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2023.10.015_bib18","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.14309\/ajg.0000000000000666","article-title":"An update on the medical management of inflammatory pouch complications","volume":"115","author":"Quinn","year":"2020","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2023.10.015_bib19","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1007\/s10350-004-6652-8","article-title":"Modified pouchitis disease activity index: a simplified approach to the diagnosis of pouchitis","volume":"46","author":"Shen","year":"2003","journal-title":"Dis Colon Rectum"},{"key":"10.1053\/j.gastro.2023.10.015_bib20","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1111\/j.1572-0241.2005.40778.x","article-title":"Comprehensive evaluation of inflammatory and noninflammatory sequelae of ileal pouch-anal anastomoses","volume":"100","author":"Shen","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2023.10.015_bib21","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1053\/j.gastro.2022.12.007","article-title":"AGA Clinical Practice Guideline on the role of biomarkers for the management of ulcerative colitis","volume":"164","author":"Singh","year":"2023","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2023.10.015_bib22","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1097\/MEG.0b013e3282f1c9a7","article-title":"Faecal calprotectin: a noninvasive diagnostic tool and marker of severity in pouchitis","volume":"20","author":"Johnson","year":"2008","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2023.10.015_bib23","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1016\/j.cgh.2021.11.012","article-title":"Fecal calprotectin is increased in pouchitis and progressively increases with more severe endoscopic and histologic disease","volume":"20","author":"Ollech","year":"2022","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2023.10.015_bib24","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1038\/ajg.2015.129","article-title":"Consecutive monitoring of fecal calprotectin and lactoferrin for the early diagnosis and prediction of pouchitis after restorative proctocolectomy for ulcerative colitis","volume":"110","author":"Yamamoto","year":"2015","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2023.10.015_bib25","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.14309\/ajg.0000000000002348","article-title":"Classification and management of disorders of the j pouch","volume":"118","author":"Santiago","year":"2023","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2023.10.015_bib26","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1111\/apt.16859","article-title":"Defining normal pouch function in patients with ileal pouch-anal anastomosis: a pilot study","volume":"55","author":"Quinn","year":"2022","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1053\/j.gastro.2023.10.015_bib27","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1016\/j.cgh.2017.02.024","article-title":"Nonrelaxing pelvic floor dysfunction is an underestimated complication of ileal pouch-anal anastomosis","volume":"15","author":"Quinn","year":"2017","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2023.10.015_bib28","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1016\/S0016-5085(03)00171-9","article-title":"Prophylaxis of pouchitis onset with probiotic therapy: a double-blind, placebo-controlled trial","volume":"124","author":"Gionchetti","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2023.10.015_bib29","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1053\/j.gastro.2016.10.012","article-title":"Roles for intestinal bacteria, viruses, and fungi in pathogenesis of inflammatory bowel diseases and therapeutic approaches","volume":"152","author":"Sartor","year":"2017","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2023.10.015_bib30","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1007\/s00595-015-1261-9","article-title":"The effect of Clostridium butyricum MIYAIRI on the prevention of pouchitis and alteration of the microbiota profile in patients with ulcerative colitis","volume":"46","author":"Yasueda","year":"2016","journal-title":"Surg Today"},{"key":"10.1053\/j.gastro.2023.10.015_bib31","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1002\/ibd.20369","article-title":"Probiotic administration in patients with ileal pouch-anal anastomosis for ulcerative colitis is associated with expansion of mucosal regulatory cells","volume":"14","author":"Pronio","year":"2008","journal-title":"Inflamm Bowel Dis"},{"issue":"4 Suppl 2","key":"10.1053\/j.gastro.2023.10.015_bib32","first-page":"S465","article-title":"Bifidobacterium longum BB-536 and prevention of acute pouchitis","volume":"126","author":"Brown","year":"2004","journal-title":"Gastroenterology"},{"issue":"5 Suppl","key":"10.1053\/j.gastro.2023.10.015_bib33","first-page":"S69","article-title":"488 Early institution of tinidazole may prevent pouchitis following ileal-pouch anal anastomosis (IPAA) surgery in ulcerative colitis (UC) patients","volume":"138","author":"Ha","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2023.10.015_bib34","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1053\/j.gastro.2019.10.001","article-title":"Predominantly antibiotic-resistant intestinal microbiome persists in patients with pouchitis who respond to antibiotic therapy","volume":"158","author":"Dubinsky","year":"2020","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2023.10.015_bib35","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1093\/ibd\/izac043","article-title":"Vancomycin is effective in the treatment of chronic inflammatory conditions of the pouch","volume":"28","author":"Lupu","year":"2022","journal-title":"Inflammatory bowel diseases"},{"key":"10.1053\/j.gastro.2023.10.015_bib36","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1002\/ibd.20187","article-title":"Rifaximin for the treatment of active pouchitis: a randomized, double-blind, placebo-controlled pilot study","volume":"13","author":"Isaacs","year":"2007","journal-title":"Inflamm Bowel Dis"},{"key":"10.1053\/j.gastro.2023.10.015_bib37","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S2468-1253(21)00214-4","article-title":"Treatment of pouchitis, Crohn's disease, cuffitis, and other inflammatory disorders of the pouch: consensus guidelines from the International Ileal Pouch Consortium","volume":"7","author":"Shen","year":"2022","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2023.10.015_bib38","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1097\/00054725-200111000-00004","article-title":"A\u00a0randomized clinical trial of ciprofloxacin and metronidazole to treat acute pouchitis","volume":"7","author":"Shen","year":"2001","journal-title":"Inflamm Bowel Dis"},{"key":"10.1053\/j.gastro.2023.10.015_bib39","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1046\/j.1365-2036.2002.01203.x","article-title":"Four-week open-label trial of metronidazole and ciprofloxacin for the treatment of recurrent or refractory pouchitis","volume":"16","author":"Mimura","year":"2002","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1053\/j.gastro.2023.10.015_bib40","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1007\/s10350-007-9068-4","article-title":"High-dose probiotics for the treatment of active pouchitis","volume":"50","author":"Gionchetti","year":"2007","journal-title":"Dis Colon Rectum"},{"key":"10.1053\/j.gastro.2023.10.015_bib41","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1080\/00365520410009339","article-title":"Outcome of four weeks' intervention with probiotics on symptoms and endoscopic appearance after surgical reconstruction with a J-configurated ileal-pouch-anal-anastomosis in ulcerative colitis","volume":"40","author":"Laake","year":"2005","journal-title":"Scand J Gastroenterol"},{"key":"10.1053\/j.gastro.2023.10.015_bib42","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1046\/j.1365-2036.2003.01465.x","article-title":"Effect of Lactobacillus rhamnosus GG on ileal pouch inflammation and microbial flora","volume":"17","author":"Kuisma","year":"2003","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1053\/j.gastro.2023.10.015_bib43","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1080\/00365520310000906","article-title":"Assessment of mucosal inflammation and circulation in response to probiotics in patients operated with ileal pouch anal anastomosis for ulcerative colitis","volume":"38","author":"Laake","year":"2003","journal-title":"Scand J Gastroenterol"},{"key":"10.1053\/j.gastro.2023.10.015_bib44","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1053\/gast.2000.9370","article-title":"Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: a double-blind, placebo-controlled trial","volume":"119","author":"Gionchetti","year":"2000","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2023.10.015_bib45","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1136\/gut.53.1.108","article-title":"Once daily high dose probiotic therapy (VSL#3) for maintaining remission in recurrent or refractory pouchitis","volume":"53","author":"Mimura","year":"2004","journal-title":"Gut"},{"key":"10.1053\/j.gastro.2023.10.015_bib46","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1093\/ibd\/izab209","article-title":"Long-term antibiotic treatment in pouchitis - patterns of use and safety","volume":"28","author":"Bar","year":"2022","journal-title":"Inflamm Bowel Dis"},{"key":"10.1053\/j.gastro.2023.10.015_bib47","first-page":"932","article-title":"Prevalence of Clostridioides difficile infection after ileal pouch-anal anastomosis in patients with chronic antibiotic-dependent pouchitis and Crohn's-like disease of the pouch","volume":"23","author":"Shore","year":"2022","journal-title":"Inflamm Bowel Dis"},{"issue":"Suppl1","key":"10.1053\/j.gastro.2023.10.015_bib48","first-page":"S13","article-title":"Type and durability of antibiotic therapy among patients with chronic antibiotic dependent pouchitis","volume":"114","author":"Weaver","year":"2019","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2023.10.015_bib49","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.cgh.2022.01.033","article-title":"Early biologic initiation after chronic pouch inflammation diagnosis does not impact clinical outcomes","volume":"21","author":"Kayal","year":"2023","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2023.10.015_bib50","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/j.cgh.2020.07.008","article-title":"Recycling of precolectomy anti-tumor necrosis factor agents in chronic pouch inflammation is associated with treatment failure","volume":"19","author":"Kayal","year":"2021","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2023.10.015_bib51","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1080\/00365521.2022.2110383","article-title":"Is biologic therapy effective for antibiotic-refractory pouchitis?","volume":"58","author":"Lindh","year":"2023","journal-title":"Scand J Gastroenterol"},{"issue":"Suppl 1","key":"10.1053\/j.gastro.2023.10.015_bib52","doi-asserted-by":"crossref","first-page":"i402","DOI":"10.1093\/ecco-jcc\/jjab232.539","article-title":"Drug persistence and endoscopic, histologic and biochemical remission rates among patients following ileal pouch-anal anastomosis treated with biologic therapy: results from a prospective patient cohort","volume":"16","author":"Ollech","year":"2022","journal-title":"J\u00a0Crohns Colitis"},{"key":"10.1053\/j.gastro.2023.10.015_bib53","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1097\/MEG.0b013e3283525a7b","article-title":"Efficacy of adalimumab rescue therapy in patients with chronic refractory pouchitis previously treated with infliximab: a case series","volume":"24","author":"Barreiro-De Acosta","year":"2012","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2023.10.015_bib54","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1111\/j.1365-2036.2008.03656.x","article-title":"Short-term treatment with infliximab in chronic refractory pouchitis and ileitis","volume":"27","author":"Calabrese","year":"2008","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1053\/j.gastro.2023.10.015_bib55","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1002\/ibd.21037","article-title":"Efficacy of infliximab in refractory pouchitis and Crohn's disease-related complications of the pouch: a Belgian case series","volume":"16","author":"Ferrante","year":"2010","journal-title":"Inflamm Bowel Dis"},{"key":"10.1053\/j.gastro.2023.10.015_bib56","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1093\/ecco-jcc\/jjv225","article-title":"Infliximab to treat refractory inflammation after pelvic pouch surgery for ulcerative colitis","volume":"10","author":"Kelly","year":"2016","journal-title":"J\u00a0Crohns Colitis"},{"key":"10.1053\/j.gastro.2023.10.015_bib57","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1080\/00365521.2019.1569718","article-title":"Adalimumab in the treatment of chronic pouchitis. A randomized double-blind, placebo-controlled trial","volume":"54","author":"Kjaer","year":"2019","journal-title":"Scand J Gastroenterol"},{"issue":"1","key":"10.1053\/j.gastro.2023.10.015_bib58","first-page":"S126","article-title":"Management of patients with ulcerative colitis after proctocolectomy: pouchitis is a frequent complication, sometimes with the need for biological therapy","volume":"5","author":"Molnar","year":"2011","journal-title":"J\u00a0Crohns Colitis"},{"issue":"Suppl 2","key":"10.1053\/j.gastro.2023.10.015_bib59","first-page":"A41","article-title":"Long term outcomes of initial infliximab therapy for inflammatory pouch pathology: a multi-centre retrospective study","volume":"67","author":"Segal","year":"2018","journal-title":"Gut"},{"key":"10.1053\/j.gastro.2023.10.015_bib60","first-page":"14","article-title":"Efficacy of biologic therapy in chronic pouchitis developing after proctocolectomy and ileal-pouch anal anastomosis (IPAA) in ulcerative colitis (UC) patients","volume":"6","author":"Tulchinsky","year":"2011","journal-title":"Colorectal Dis"},{"key":"10.1053\/j.gastro.2023.10.015_bib61","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1159\/000438922","article-title":"Clinical features of refractory pouchitis with penetrating lesions and the efficacy of infliximab treatment for patients with ulcerative colitis after restorative proctocolectomy","volume":"92","author":"Uchino","year":"2015","journal-title":"Digestion"},{"issue":"Suppl 1","key":"10.1053\/j.gastro.2023.10.015_bib62","doi-asserted-by":"crossref","first-page":"S385","DOI":"10.1093\/ecco-jcc\/jjy222.666","article-title":"Efficacy and safety of biological therapies in chronic antibiotic-refractory pouchitis: a retrospective single-centre experience","volume":"13","author":"Verstockt","year":"2019","journal-title":"J\u00a0Crohns Colitis"},{"issue":"Suppl 1","key":"10.1053\/j.gastro.2023.10.015_bib63","doi-asserted-by":"crossref","first-page":"S189","DOI":"10.1016\/S1873-9946(13)60468-7","article-title":"Long term benefit of one year infliximab administration for the treatment of chronic refractory pouchitis","volume":"7","author":"Viazis","year":"2013","journal-title":"J\u00a0Crohn Colitis"},{"key":"10.1053\/j.gastro.2023.10.015_bib64","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1046\/j.1365-2036.2003.01535.x","article-title":"Infliximab in refractory pouchitis complicated by fistulae following ileo-anal pouch for ulcerative colitis","volume":"17","author":"Viscido","year":"2003","journal-title":"Aliment Pharmacol Ther"},{"issue":"Suppl","key":"10.1053\/j.gastro.2023.10.015_bib65","doi-asserted-by":"crossref","first-page":"S1679","DOI":"10.14309\/01.ajg.0000714856.39315.e7","article-title":"Treatment of chronic pouchitis with tofacitinib: real world experience from a tertiary center","volume":"115","author":"Akiyama","year":"2020","journal-title":"Am J Gastroenterol"},{"issue":"6 Suppl 1","key":"10.1053\/j.gastro.2023.10.015_bib66","doi-asserted-by":"crossref","first-page":"S884","DOI":"10.1016\/S0016-5085(19)39181-4","article-title":"Ustekinumab is effective for the treatment of chronic antibiotic-refractory pouchitis","volume":"156","author":"Ollech","year":"2019","journal-title":"Gastroenterology"},{"issue":"7 Suppl","key":"10.1053\/j.gastro.2023.10.015_bib67","doi-asserted-by":"crossref","first-page":"S826","DOI":"10.1016\/S0016-5085(22)61942-5","article-title":"Effectiveness of ustekinumab as induction therapy for chronic antibiotic refractory pouchitis","volume":"162","author":"Outtier","year":"2022","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2023.10.015_bib68","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1111\/apt.14479","article-title":"Vedolizumab in the treatment of chronic, antibiotic-dependent or refractory pouchitis","volume":"47","author":"Bar","year":"2018","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1053\/j.gastro.2023.10.015_bib69","doi-asserted-by":"crossref","first-page":"otac030","DOI":"10.1093\/crocol\/otac030","article-title":"Treatment patterns and standardized outcome assessments among patients with inflammatory conditions of the pouch in a prospective multicenter registry","volume":"4","author":"Barnes","year":"2022","journal-title":"Crohns Colitis 360"},{"issue":"Suppl 1","key":"10.1053\/j.gastro.2023.10.015_bib70","doi-asserted-by":"crossref","first-page":"S341","DOI":"10.1093\/ecco-jcc\/jjy222.583","article-title":"Vedolizumab for the treatment of chronic pouchitis: the Edinburgh experience","volume":"13","author":"Cesano","year":"2019","journal-title":"J\u00a0Crohns Colitis"},{"key":"10.1053\/j.gastro.2023.10.015_bib71","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1093\/ibd\/izz030","article-title":"Efficacy of vedolizumab for refractory pouchitis of the ileo-anal pouch: results from a multicenter US cohort","volume":"25","author":"Gregory","year":"2019","journal-title":"Inflamm Bowel Dis"},{"issue":"1","key":"10.1053\/j.gastro.2023.10.015_bib72","doi-asserted-by":"crossref","first-page":"e5","DOI":"10.1097\/MIB.0000000000000992","article-title":"Efficacy of vedolizumab in patients with antibiotic and anti-tumor necrosis alpha refractory pouchitis","volume":"23","author":"Philpott","year":"2017","journal-title":"Inflamm Bowel Dis"},{"issue":"7 Suppl","key":"10.1053\/j.gastro.2023.10.015_bib73","doi-asserted-by":"crossref","first-page":"S822","DOI":"10.1016\/S0016-5085(22)61937-1","article-title":"Efficacy and safety of vedolizumab in patients with chronic active pouchitis refractory to anti-Tnf Therapy: results of a retrospective multicenter study","volume":"162","author":"Sallette","year":"2022","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2023.10.015_bib74","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1093\/gastro\/goz001","article-title":"Vedolizumab for chronic antibiotic-refractory pouchitis","volume":"7","author":"Singh","year":"2019","journal-title":"Gastroenterology Report"},{"key":"10.1053\/j.gastro.2023.10.015_bib75","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1093\/ibd\/izz227","article-title":"Inflammatory pouch conditions are common after ileal pouch anal anastomosis in ulcerative colitis patients","volume":"26","author":"Kayal","year":"2020","journal-title":"Inflamm Bowel Dis"},{"key":"10.1053\/j.gastro.2023.10.015_bib76","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1016\/j.dld.2021.03.027","article-title":"Chronic pouchitis and Crohn's disease of the pouch after ileal pouch-anal anastomosis: incidence and risk factors","volume":"53","author":"Bresteau","year":"2021","journal-title":"Dig Liver Dis"},{"issue":"5 Suppl 1","key":"10.1053\/j.gastro.2023.10.015_bib77","doi-asserted-by":"crossref","first-page":"AB269","DOI":"10.1016\/j.gie.2017.03.608","article-title":"Adalimumab in the treatment of chronic pouchitis.a randomized double-blind, placebo-controlled trial","volume":"85","author":"Kjaer","year":"2017","journal-title":"Gastrointestinal Endoscopy"},{"key":"10.1053\/j.gastro.2023.10.015_bib78","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1002\/ibd.21911","article-title":"Etiology of pouchitis","volume":"18","author":"Landy","year":"2012","journal-title":"Inflamm Bowel Dis"},{"key":"10.1053\/j.gastro.2023.10.015_bib79","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1093\/ibd\/izab030","article-title":"Computational learning of microRNA-based prediction of pouchitis outcome after restorative proctocolectomy in patients with ulcerative colitis","volume":"27","author":"Morilla","year":"2021","journal-title":"Inflamm Bowel Dis"},{"key":"10.1053\/j.gastro.2023.10.015_bib80","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1111\/apt.12274","article-title":"Meta-analysis: serological markers and the risk of acute and chronic pouchitis","volume":"37","author":"Singh","year":"2013","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1053\/j.gastro.2023.10.015_bib81","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1136\/gutjnl-2011-301957","article-title":"The NOD2insC polymorphism is associated with worse outcome following ileal pouch-anal anastomosis for ulcerative colitis","volume":"62","author":"Tyler","year":"2013","journal-title":"Gut"},{"key":"10.1053\/j.gastro.2023.10.015_bib82","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1093\/ecco-jcc\/jjw134","article-title":"Outcomes with anti-tumour necrosis factor-alpha therapy and serology in patients with denovo Crohn's disease after ileal pouch anal anastomosis","volume":"11","author":"Robbins","year":"2017","journal-title":"J\u00a0Crohns Colitis"},{"key":"10.1053\/j.gastro.2023.10.015_bib83","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1177\/2050640619871797","article-title":"Outcome of biological therapies in chronic antibiotic-refractory pouchitis: a retrospective single-centre experience","volume":"7","author":"Verstockt","year":"2019","journal-title":"United European Gastroenterol J"},{"key":"10.1053\/j.gastro.2023.10.015_bib84","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1111\/j.1365-2036.2007.03306.x","article-title":"Oral budesonide in the treatment of chronic refractory pouchitis","volume":"25","author":"Gionchetti","year":"2007","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1053\/j.gastro.2023.10.015_bib85","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.crohns.2013.12.001","article-title":"Oral beclomethasone dipropionate in chronic refractory pouchitis","volume":"8","author":"Gionchetti","year":"2014","journal-title":"J\u00a0Crohns Colitis"},{"key":"10.1053\/j.gastro.2023.10.015_bib86","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.14309\/ajg.0000000000001774","article-title":"Budesonide maintenance in microscopic colitis: clinical outcomes and safety profile from a population-based study","volume":"117","author":"Tome","year":"2022","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2023.10.015_bib87","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1111\/j.1365-2036.2009.04163.x","article-title":"Pilot study: the use of sulfasalazine for the treatment of acute pouchitis","volume":"31","author":"Belluzzi","year":"2010","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1053\/j.gastro.2023.10.015_bib88","first-page":"14","article-title":"The safety of sulfasalazine: the gastroenterologists' experience","volume":"16","author":"Sachar","year":"1988","journal-title":"J\u00a0Rheumatol Suppl"},{"key":"10.1053\/j.gastro.2023.10.015_bib89","doi-asserted-by":"crossref","first-page":"2239","DOI":"10.1111\/j.1572-0241.2003.07675.x","article-title":"Management of Crohn's disease of the ileoanal pouch with infliximab","volume":"98","author":"Colombel","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.gastro.2023.10.015_bib90","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/DCR.0b013e3181fc9f04","article-title":"Infliximab and\/or azathioprine in the treatment of Crohn's disease-like complications after IPAA","volume":"54","author":"Haveran","year":"2011","journal-title":"Dis Colon Rectum"},{"key":"10.1053\/j.gastro.2023.10.015_bib91","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1002\/ibd.22933","article-title":"Adalimumab therapy in Crohn's disease of the ileal pouch","volume":"18","author":"Li","year":"2012","journal-title":"Inflamm Bowel Dis"},{"key":"10.1053\/j.gastro.2023.10.015_bib92","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1053\/gast.1999.0029900429","article-title":"Successful management of Crohn's disease of the ileoanal pouch with infliximab","volume":"117","author":"Ricart","year":"1999","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2023.10.015_bib93","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1093\/ibd\/izab156","article-title":"Outcomes of standard and intensified dosing of ustekinumab for chronic pouch disorders","volume":"28","author":"Dalal","year":"2022","journal-title":"Inflamm Bowel Diseases"},{"key":"10.1053\/j.gastro.2023.10.015_bib94","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1093\/ibd\/izy302","article-title":"Ustekinumab is effective for the treatment of Crohn's disease of the pouch in a multicenter cohort","volume":"25","author":"Weaver","year":"2019","journal-title":"Inflamm Bowel Dis"},{"key":"10.1053\/j.gastro.2023.10.015_bib95","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1093\/gastro\/goy014","article-title":"Vedolizumab in the treatment of Crohn's disease of the pouch","volume":"6","author":"Khan","year":"2018","journal-title":"Gastroenterol Rep"},{"key":"10.1053\/j.gastro.2023.10.015_bib96","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1053\/j.gastro.2018.12.009","article-title":"AGA Clinical Practice Guidelines on the management of mild-to-moderate ulcerative colitis","volume":"156","author":"Ko","year":"2019","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2023.10.015_bib97","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1093\/ecco-jcc\/jjx008","article-title":"Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 1: Definitions, Diagnosis, Extra-intestinal Manifestations, Pregnancy, Cancer Surveillance, Surgery, and Ileo-anal Pouch Disorders","volume":"11","author":"Magro","year":"2017","journal-title":"J\u00a0Crohns Colitis"}],"container-title":["Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508523051429?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508523051429?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T09:52:56Z","timestamp":1762163576000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016508523051429"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":97,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["S0016508523051429"],"URL":"https:\/\/doi.org\/10.1053\/j.gastro.2023.10.015","relation":{},"ISSN":["0016-5085"],"issn-type":[{"value":"0016-5085","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"AGA Clinical Practice Guideline on the Management of Pouchitis and Inflammatory Pouch Disorders","name":"articletitle","label":"Article Title"},{"value":"Gastroenterology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.gastro.2023.10.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 by the AGA Institute.","name":"copyright","label":"Copyright"}]}}