{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T20:29:10Z","timestamp":1790022550960,"version":"4.0.1"},"reference-count":50,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T00:00:00Z","timestamp":1770163200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["R01GM127706"],"award-info":[{"award-number":["R01GM127706"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000005","name":"US Department of Defense","doi-asserted-by":"publisher","award":["W81XWH-20-1-0697"],"award-info":[{"award-number":["W81XWH-20-1-0697"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["R01DK099076"],"award-info":[{"award-number":["R01DK099076"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","gastrojournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastroenterology"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1053\/j.gastro.2026.01.023","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:32:03Z","timestamp":1770823923000},"page":"1546-1561","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Quorum-Sensing Molecules Are Elevated in Long-Standing Ulcerative Colitis and Are Linked to the Development of Colitis-Associated Cancer"],"prefix":"10.1053","volume":"170","author":[{"given":"Gregory","family":"O\u2019Connor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajar","family":"Hazime","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan F.","family":"Burgue\u00f1o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana M.","family":"Santander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nivis","family":"Brito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katerina M.","family":"Faust","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuguang","family":"Ban","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria A.","family":"Quintero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sapna K.","family":"Deo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7294-0574","authenticated-orcid":false,"given":"Maria T.","family":"Abreu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvia","family":"Daunert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/j.gastro.2026.01.023_bib1","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1159\/000527422","article-title":"New and emerging treatments for inflammatory bowel disease","volume":"104","author":"Higashiyama","year":"2023","journal-title":"Digestion"},{"key":"10.1053\/j.gastro.2026.01.023_bib2","doi-asserted-by":"crossref","first-page":"6091","DOI":"10.3390\/curroncol29090479","article-title":"Colorectal cancer in ulcerative colitis: mechanisms, surveillance and chemoprevention","volume":"29","author":"Li","year":"2022","journal-title":"Curr Oncol"},{"key":"10.1053\/j.gastro.2026.01.023_bib3","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1016\/j.cgh.2018.09.038","article-title":"Family history associates with increased risk of colorectal cancer in patients with inflammatory bowel diseases","volume":"17","author":"Samadder","year":"2019","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2026.01.023_bib4","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1053\/j.gastro.2021.05.063","article-title":"AGA clinical practice update on endoscopic surveillance and management of colorectal dysplasia in inflammatory bowel diseases: expert review","volume":"161","author":"Murthy","year":"2021","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2026.01.023_bib5","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1186\/s40064-015-1350-7","article-title":"Long-term outcomes of colectomy surgery among patients with ulcerative colitis","volume":"4","author":"Brown","year":"2015","journal-title":"SpringerPlus"},{"key":"10.1053\/j.gastro.2026.01.023_bib6","doi-asserted-by":"crossref","first-page":"005056","DOI":"10.1099\/ijsem.0.005056","article-title":"Valid publication of the names of forty-two phyla of prokaryotes","volume":"71","author":"Oren","year":"2021","journal-title":"Int J System Evolution Microbiol"},{"key":"10.1053\/j.gastro.2026.01.023_bib7","doi-asserted-by":"crossref","first-page":"1430001","DOI":"10.3389\/fimmu.2024.1430001","article-title":"The oral-gut microbiome axis in inflammatory bowel disease: from inside to insight","volume":"15","author":"Wang","year":"2024","journal-title":"Front Immunol"},{"key":"10.1053\/j.gastro.2026.01.023_bib8","doi-asserted-by":"crossref","first-page":"3377","DOI":"10.3390\/nu15153377","article-title":"Unraveling the impact of gut and oral microbiome on gut health in inflammatory bowel diseases","volume":"15","author":"Elzayat","year":"2023","journal-title":"Nutrients"},{"key":"10.1053\/j.gastro.2026.01.023_bib9","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1080\/19490976.2017.1379637","article-title":"Mucosa-associated microbiota dysbiosis in colitis associated cancer","volume":"9","author":"Richard","year":"2018","journal-title":"Gut Microbes"},{"key":"10.1053\/j.gastro.2026.01.023_bib10","doi-asserted-by":"crossref","first-page":"2728","DOI":"10.3390\/cancers12102728","article-title":"Fusobacterium nucleatum accelerates the progression of colitis-associated colorectal cancer by promoting EMT","volume":"12","author":"Yu","year":"2020","journal-title":"Cancers"},{"key":"10.1053\/j.gastro.2026.01.023_bib11","doi-asserted-by":"crossref","first-page":"6528","DOI":"10.1038\/ncomms7528","article-title":"Gut microbiome development along the colorectal adenoma\u2013carcinoma sequence","volume":"6","author":"Feng","year":"2015","journal-title":"Nat Commun"},{"key":"10.1053\/j.gastro.2026.01.023_bib12","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1053\/j.gastro.2020.10.031","article-title":"Epithelial TLR4 signaling activates DUOX2 to induce microbiota-driven tumorigenesis","volume":"160","author":"Burgue\u00f1o","year":"2021","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2026.01.023_bib13","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.3389\/fphys.2019.01484","article-title":"Intestinal epithelial cells respond to chronic inflammation and dysbiosis by synthesizing H2O2","volume":"10","author":"Burgue\u00f1o","year":"2019","journal-title":"Front Physiol"},{"key":"10.1053\/j.gastro.2026.01.023_bib14","doi-asserted-by":"crossref","DOI":"10.14309\/ctg.0000000000000547","article-title":"Bacterial quorum-sensing molecules in serum: a potential tool for Crohn's disease management","volume":"13","author":"O'Connor","year":"2022","journal-title":"Clin Transl Gastroenterol"},{"key":"10.1053\/j.gastro.2026.01.023_bib15","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.chom.2023.03.015","article-title":"Deciphering the quorum-sensing lexicon of the gut microbiota","volume":"31","author":"Oliveira","year":"2023","journal-title":"Cell Host Microbe"},{"key":"10.1053\/j.gastro.2026.01.023_bib16","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.ebiom.2016.05.037","article-title":"Serotonin activates bacterial quorum sensing and enhances the virulence of Pseudomonas aeruginosa in the host","volume":"9","author":"Knecht","year":"2016","journal-title":"EBioMedicine"},{"key":"10.1053\/j.gastro.2026.01.023_bib17","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0202587","article-title":"Inter-kingdom effect on epithelial cells of the N-Acyl homoserine lactone 3-oxo-C12:2, a major quorum-sensing molecule from gut microbiota","volume":"13","author":"Landman","year":"2018","journal-title":"PLOS ONE"},{"key":"10.1053\/j.gastro.2026.01.023_bib18","doi-asserted-by":"crossref","first-page":"G992","DOI":"10.1152\/ajpgi.00016.2014","article-title":"Disruption of epithelial barrier by quorum-sensing N-3-(oxododecanoyl)-homoserine lactone is mediated by matrix metalloproteinases","volume":"306","author":"Eum","year":"2014","journal-title":"Am J Physiol-Gastrointest Liver Physiol"},{"key":"10.1053\/j.gastro.2026.01.023_bib19","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1136\/gutjnl-2012-303207","article-title":"Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis","volume":"63","author":"Johansson","year":"2014","journal-title":"Gut"},{"key":"10.1053\/j.gastro.2026.01.023_bib20","doi-asserted-by":"crossref","first-page":"7584","DOI":"10.3390\/molecules27217584","article-title":"Molecular mechanisms and applications of N-Acyl homoserine lactone-mediated quorum sensing in bacteria","volume":"27","author":"Kumar","year":"2022","journal-title":"Molecules"},{"key":"10.1053\/j.gastro.2026.01.023_bib21","doi-asserted-by":"crossref","first-page":"5733","DOI":"10.1128\/JB.183.19.5733-5742.2001","article-title":"SdiA of Salmonella enterica is a LuxR homolog that detects mixed microbial communities","volume":"183","author":"Michael","year":"2001","journal-title":"J Bacteriol"},{"key":"10.1053\/j.gastro.2026.01.023_bib22","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1099\/mic.0.026849-0","article-title":"LuxR-family \u2018solos\u2019: bachelor sensors\/regulators of signalling molecules","volume":"155","author":"Subramoni","year":"2009","journal-title":"Microbiology"},{"key":"10.1053\/j.gastro.2026.01.023_bib23","first-page":"1","article-title":"Full, partial, and modified permutations of the Mayo Score: characterizing clinical and patient-reported outcomes in ulcerative colitis patients","volume":"360","author":"Naegeli","year":"2021","journal-title":"Crohn's Colitis"},{"key":"10.1053\/j.gastro.2026.01.023_bib24","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1089\/neu.2017.5349","article-title":"Investigation of microbiota alterations and intestinal inflammation post-spinal cord injury in rat model","volume":"35","author":"O'Connor","year":"2018","journal-title":"J Neurotrauma"},{"key":"10.1053\/j.gastro.2026.01.023_bib25","doi-asserted-by":"crossref","DOI":"10.14309\/ctg.0000000000000547","article-title":"Bacterial quorum-sensing molecules in serum: a potential tool for Crohn's disease management","volume":"13","author":"O'Connor","year":"2022","journal-title":"Clin Transl Gastroenterol"},{"key":"10.1053\/j.gastro.2026.01.023_bib26","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.canlet.2013.07.032","article-title":"Chronic ulcerative colitis and colorectal cancer","volume":"345","author":"Rogler","year":"2014","journal-title":"Cancer Letters"},{"key":"10.1053\/j.gastro.2026.01.023_bib27","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1053\/j.gastro.2007.08.001","article-title":"Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: a cohort study","volume":"133","author":"Gupta","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1053\/j.gastro.2026.01.023_bib28","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1097\/MEG.0000000000000576","article-title":"Increased risk of colorectal neoplasia in patients with primary sclerosing cholangitis and inflammatory bowel disease","volume":"28","author":"Zheng","year":"2016","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2026.01.023_bib29","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.jmii.2024.09.006","article-title":"Alternations of the gut microbiota and the Firmicutes\/Bacteroidetes ratio after biologic treatment in inflammatory bowel disease","volume":"58","author":"Tsai","year":"2024","journal-title":"J Microbiol Immunol Infection"},{"key":"10.1053\/j.gastro.2026.01.023_bib30","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.3390\/biomedicines10051128","article-title":"Faecalibacterium prausnitzii ameliorates colorectal tumorigenesis and suppresses proliferation of HCT116 colorectal cancer cells","volume":"10","author":"Dikeocha","year":"2022","journal-title":"Biomedicines"},{"key":"10.1053\/j.gastro.2026.01.023_bib31","article-title":"The microbiome types of colorectal tissue are potentially associated with the prognosis of patients with colorectal cancer","volume":"14","author":"Xu","year":"2023","journal-title":"Front Microbiol"},{"key":"10.1053\/j.gastro.2026.01.023_bib32","doi-asserted-by":"crossref","first-page":"658354","DOI":"10.3389\/fimmu.2021.658354","article-title":"Impact of bacterial metabolites on gut barrier function and host immunity: a focus on bacterial metabolism and its relevance for intestinal inflammation","volume":"12","author":"Gasaly","year":"2021","journal-title":"Front Immunol"},{"key":"10.1053\/j.gastro.2026.01.023_bib33","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1038\/msb.2008.56","article-title":"Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes","volume":"4","author":"Claus","year":"2008","journal-title":"Mol Syst Biol"},{"key":"10.1053\/j.gastro.2026.01.023_bib34","first-page":"8984","article-title":"A weighted relative difference accumulation algorithm for dynamic metabolomics data: long-term elevated bile acids are risk factors for hepatocellular carcinoma","volume":"5","author":"Zhang","year":"2015","journal-title":"Scientif Rep"},{"key":"10.1053\/j.gastro.2026.01.023_bib35","doi-asserted-by":"crossref","first-page":"579","DOI":"10.3390\/nu14030579","article-title":"Lysophosphatidylethanolamine affects lipid accumulation and metabolism in a human liver-derived cell line","volume":"14","author":"Yamamoto","year":"2022","journal-title":"Nutrients"},{"key":"10.1053\/j.gastro.2026.01.023_bib36","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.peptides.2014.12.009","article-title":"Crosstalk between the microbiome and cancer cells by quorum sensing peptides","volume":"64","author":"Wynendaele","year":"2015","journal-title":"Peptides"},{"key":"10.1053\/j.gastro.2026.01.023_bib37","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1186\/s12915-022-01317-z","article-title":"The quorum sensing peptide EntF\u2217 promotes colorectal cancer metastasis in mice: a new factor in the host-microbiome interaction","volume":"20","author":"Wynendaele","year":"2022","journal-title":"BMC Biol"},{"key":"10.1053\/j.gastro.2026.01.023_bib38","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0147468","article-title":"Expression of the bitter taste receptor, T2R38, in enteroendocrine cells of the colonic mucosa of overweight\/obese vs. lean subjects","volume":"11","author":"Latorre","year":"2016","journal-title":"PLoS One"},{"key":"10.1053\/j.gastro.2026.01.023_bib39","doi-asserted-by":"crossref","first-page":"5295","DOI":"10.3390\/ijms24065295","article-title":"Serum CXCL5 detects early hepatocellular carcinoma and indicates tumor progression","volume":"24","author":"Laschtowitz","year":"2023","journal-title":"Int J Mol Sci"},{"key":"10.1053\/j.gastro.2026.01.023_bib40","doi-asserted-by":"crossref","first-page":"1358750","DOI":"10.3389\/fonc.2024.1358750","article-title":"Macrophage colony-stimulating factor and its role in the tumor microenvironment: novel therapeutic avenues and mechanistic insights","volume":"14","author":"Yi","year":"2024","journal-title":"Front Oncol"},{"key":"10.1053\/j.gastro.2026.01.023_bib41","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2023.1184703","article-title":"Research progress of interleukin-15 in cancer immunotherapy","volume":"14","author":"Cai","year":"2023","journal-title":"Front Pharmacol"},{"key":"10.1053\/j.gastro.2026.01.023_bib42","doi-asserted-by":"crossref","first-page":"4755","DOI":"10.3390\/cancers14194755","article-title":"Tumor-associated neutrophils in colorectal cancer development, progression and immunotherapy","volume":"14","author":"Zheng","year":"2022","journal-title":"Cancers (Basel)"},{"key":"10.1053\/j.gastro.2026.01.023_bib43","doi-asserted-by":"crossref","first-page":"e319","DOI":"10.1097\/SLA.0000000000005339","article-title":"Survival outcomes and clinicopathological features in inflammatory bowel disease-associated colorectal cancer","volume":"276","author":"Lu","year":"2022","journal-title":"Ann Surg"},{"key":"10.1053\/j.gastro.2026.01.023_bib44","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0140-6736(19)32545-0","article-title":"Colorectal cancer in ulcerative colitis: a Scandinavian population-based cohort study","volume":"395","author":"Ol\u00e9n","year":"2020","journal-title":"The Lancet"},{"key":"10.1053\/j.gastro.2026.01.023_bib45","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/s41575-019-0261-4","article-title":"Epithelial Toll-like receptors and their role in gut homeostasis and disease","volume":"17","author":"Burgueno","year":"2020","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1053\/j.gastro.2026.01.023_bib46","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/19490976.2023.2252780","article-title":"Targeting microbial quorum sensing: the next frontier to hinder bacterial driven gastrointestinal infections","volume":"15","author":"Su","year":"2023","journal-title":"Gut Microbes"},{"key":"10.1053\/j.gastro.2026.01.023_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2023.115494","article-title":"Engineered biosensors for the quorum sensing molecule 3,5-dimethyl-pyrazine-2-ol (DPO) reveal its presence in humans, animals, and bacterial species beyond Vibrio cholerae","volume":"237","author":"Moraskie","year":"2023","journal-title":"Biosens Bioelectron"},{"key":"10.1053\/j.gastro.2026.01.023_bib48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/femsre\/fuad031","article-title":"Quorum sensing architecture network in Escherichia coli virulence and pathogenesis","volume":"47","author":"Mayer","year":"2023","journal-title":"FEMS Microbiol Rev"},{"key":"10.1053\/j.gastro.2026.01.023_bib49","first-page":"1","article-title":"Roles of macrophages on ulcerative colitis and colitis-associated colorectal cancer","volume":"14","author":"Zhang","year":"2023","journal-title":"Front Immunol"},{"key":"10.1053\/j.gastro.2026.01.023_bib50","first-page":"1","article-title":"Patient adherence to fecal calprotectin testing is low compared to other commonly ordered tests in patients with inflammatory bowel disease","volume":"360","author":"Khakoo","year":"2021","journal-title":"Crohn's Colitis"}],"container-title":["Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508526000909?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508526000909?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T20:43:02Z","timestamp":1788295382000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016508526000909"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":50,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S0016508526000909"],"URL":"https:\/\/doi.org\/10.1053\/j.gastro.2026.01.023","relation":{},"ISSN":["0016-5085"],"issn-type":[{"value":"0016-5085","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Quorum-Sensing Molecules Are Elevated in Long-Standing Ulcerative Colitis and Are Linked to the Development of Colitis-Associated Cancer","name":"articletitle","label":"Article Title"},{"value":"Gastroenterology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.gastro.2026.01.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc. on behalf of American Gastroenterological Association Institute.","name":"copyright","label":"Copyright"}]}}