{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T08:55:33Z","timestamp":1759481733869},"reference-count":39,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Renal Nutrition"],"published-print":{"date-parts":[[2005,1]]},"DOI":"10.1053\/j.jrn.2004.09.008","type":"journal-article","created":{"date-parts":[[2006,1,10]],"date-time":"2006-01-10T15:34:26Z","timestamp":1136907266000},"page":"13-17","source":"Crossref","is-referenced-by-count":14,"title":["Role of carnitine in modulating acute-phase protein synthesis in hemodialysis patients"],"prefix":"10.1053","volume":"15","author":[{"given":"Guido","family":"Bellinghieri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenico","family":"Santoro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Menotti","family":"Calvani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Savica","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1053\/j.jrn.2004.09.008_bib1","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1053\/ajkd.2001.29222","article-title":"A malnutrition-inflammation score is correlated with morbidity and mortality in maintenance hemodialysis patients","volume":"38","author":"Kalantar-Zadeh","year":"2001","journal-title":"Am J Kidney Dis"},{"issue":"suppl 8","key":"10.1053\/j.jrn.2004.09.008_bib2","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1093\/ndt\/17.suppl_8.33","article-title":"Inflammation in end-stage renal failure","volume":"17","author":"Stenvinkel","year":"2002","journal-title":"Nephrol Dial Transplant"},{"key":"10.1053\/j.jrn.2004.09.008_bib3","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1159\/000046988","article-title":"Role of inflammation and its treatment in ESRD patients","volume":"20","author":"Kaysen","year":"2002","journal-title":"Blood Purif"},{"key":"10.1053\/j.jrn.2004.09.008_bib4","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/S0272-6386(03)00413-X","article-title":"Lipoprotein(a) and prevalent cardiovascular disease in a dialysis population","volume":"42","author":"Longenecker","year":"2003","journal-title":"Am J Kidney Dis"},{"issue":"suppl 1","key":"10.1053\/j.jrn.2004.09.008_bib5","doi-asserted-by":"crossref","first-page":"S28","DOI":"10.1681\/ASN.V13suppl_1s28","article-title":"Inflammation, malnutrition, and cardiac disease as predictors of mortality in hemodialysis patients","volume":"13","author":"Qureshi","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"10.1053\/j.jrn.2004.09.008_bib6","doi-asserted-by":"crossref","first-page":"2152","DOI":"10.1172\/JCI118653","article-title":"Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters","volume":"97","author":"Grunfeld","year":"1996","journal-title":"J Clin Invest"},{"key":"10.1053\/j.jrn.2004.09.008_bib7","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/S0272-6386(12)70364-5","article-title":"Death risk in hemodialysis patients","volume":"15","author":"Lowrie","year":"1990","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/j.jrn.2004.09.008_bib8","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1046\/j.1523-1755.1999.00615.x","article-title":"Body weight for height relationships predict mortality in maintenance hemodialysis patients","volume":"56","author":"Kopple","year":"1999","journal-title":"Kidney Int"},{"key":"10.1053\/j.jrn.2004.09.008_bib9","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1159\/000057455","article-title":"Inflammation nutritional state and outcome in end-stage renal disease","volume":"25","author":"Kaysen","year":"1999","journal-title":"Miner Electrolytes Metab"},{"issue":"suppl 1","key":"10.1053\/j.jrn.2004.09.008_bib10","doi-asserted-by":"crossref","first-page":"S247","DOI":"10.1093\/jn\/129.1.247S","article-title":"Pathophysiology of protein-energy wasting in chronic renal failure","volume":"129","author":"Kopple","year":"1999","journal-title":"J Nutr"},{"key":"10.1053\/j.jrn.2004.09.008_bib11","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/S0272-6386(98)70148-9","article-title":"Malnutrition, cardiac disease, and mortality. An integrated point of view","volume":"32","author":"Bergstrom","year":"1988","journal-title":"Am J Kidney Dis"},{"issue":"suppl 4","key":"10.1053\/j.jrn.2004.09.008_bib12","first-page":"S105","article-title":"Acute phase inflammatory process contributes to malnutrition, anemia and possibly other abnormalities in dialysis patients","volume":"32","author":"Lowrie","year":"1988","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/j.jrn.2004.09.008_bib13","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1177\/039139889802100102","article-title":"Cytokines production and nutritional status in hemodialysis patients","volume":"21","author":"King","year":"1998","journal-title":"Int J Artif Organs"},{"key":"10.1053\/j.jrn.2004.09.008_bib14","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1093\/ndt\/15.7.953","article-title":"Are there two types of malnutrition in chronic renal failure? Evidence for relationship between malnutrition, inflammation and atherosclerosis (MIA syndrome)","volume":"15","author":"Stenvinkel","year":"2000","journal-title":"Nephrol Dial Transplant"},{"key":"10.1053\/j.jrn.2004.09.008_bib15","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1056\/NEJM199309303291404","article-title":"The urea reduction ratio and serum albumin concentration as predictor of mortality in patients undergoing hemodialysis","volume":"329","author":"Owen","year":"1993","journal-title":"N Engl J Med"},{"key":"10.1053\/j.jrn.2004.09.008_bib16","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1053\/ajkd.2002.31766","article-title":"What are the causes of protein-energy malnutrition in chronic renal insufficiency?","volume":"39","author":"Lindholm","year":"2002","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/j.jrn.2004.09.008_bib17","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1159\/000057462","article-title":"Regulation of appetite in chronic renal failure","volume":"25","author":"Bergstrom","year":"1999","journal-title":"Miner Electrolyte Metab"},{"key":"10.1053\/j.jrn.2004.09.008_bib18","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S1051-2276(99)90050-X","article-title":"Mechanisms of uremic suppression of appetite","volume":"9","author":"Bergstrom","year":"1999","journal-title":"J Ren Nutr"},{"key":"10.1053\/j.jrn.2004.09.008_bib19","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0163-7827(99)00002-8","article-title":"Carnitine acyltransferase","volume":"38","author":"Zammit","year":"1999","journal-title":"Prog Lipid Res"},{"key":"10.1053\/j.jrn.2004.09.008_bib20","doi-asserted-by":"crossref","first-page":"2244","DOI":"10.1172\/JCI119034","article-title":"Glucose plus insulin regulate fax oxidation by controlling the rate of fatty acid entry into the mitochondria","volume":"98","author":"Sidossis","year":"1996","journal-title":"J Clin Invest"},{"key":"10.1053\/j.jrn.2004.09.008_bib21","series-title":"Carnitine Today","first-page":"1","article-title":"The role of carnitine in cell metabolism","author":"Bremer","year":"1997"},{"issue":"suppl 1","key":"10.1053\/j.jrn.2004.09.008_bib22","doi-asserted-by":"crossref","first-page":"S116","DOI":"10.1053\/ajkd.2003.50099","article-title":"Carnitine and hemodialysis","volume":"41","author":"Bellinghieri","year":"2003","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/j.jrn.2004.09.008_bib23","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1053\/jren.2003.50010","article-title":"History of L-carnitine","volume":"13","author":"Matera","year":"2003","journal-title":"J Ren Nutr"},{"key":"10.1053\/j.jrn.2004.09.008_bib24","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1067\/mcp.2000.108850","article-title":"Pharmacokinetics of L-carnitine in patients with end-stage renal disease undergoing long-term haemodialysis","volume":"68","author":"Evans","year":"2000","journal-title":"Clin Pharmacol Ther"},{"key":"10.1053\/j.jrn.2004.09.008_bib25","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1093\/ajcn\/38.4.523","article-title":"Correlation between increased serum and tissue L-carnitine levels and improved muscle symptoms in hemodialyzed patients","volume":"38","author":"Bellinghieri","year":"1983","journal-title":"Am J Clin Nutr"},{"key":"10.1053\/j.jrn.2004.09.008_bib26","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1016\/S0272-6386(05)80019-8","article-title":"Intravenous L-carnitine increases plasma carnitine, reduces fatigue, and may preserve exercise capacity in hemodialysis","volume":"37","author":"Brass","year":"2001","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/j.jrn.2004.09.008_bib27","first-page":"885","article-title":"The efficacy of the substitution of carnivit in patients with chronic failure treated with hemodialysis","volume":"102","author":"Wanic-Kossowska Mpiszczek","year":"1999","journal-title":"Pol Arch Med Wewn"},{"key":"10.1053\/j.jrn.2004.09.008_bib28","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1681\/ASN.V133708","article-title":"Effects of L-carnitine supplementation in maintenance hemodialysis patients","volume":"13","author":"Hurot","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"10.1053\/j.jrn.2004.09.008_bib29","first-page":"2","article-title":"FDA approva l\u2019uso preventivo e terapeutico della L-Carnitina in Emodialisi","volume":"3","author":"Bellinghieri","year":"2000","journal-title":"Dialisi Aggiornamenti in Nefrologia (Pensiero Scientifico Editore)"},{"key":"10.1053\/j.jrn.2004.09.008_bib30","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1046\/j.1525-139x.2000.00044.x","article-title":"What are the consequences of the chronic inflammatory state in chronic dialysis patients?","volume":"13","author":"Bergstrom","year":"2000","journal-title":"Semin Dial"},{"key":"10.1053\/j.jrn.2004.09.008_bib31","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1155\/S0962935193000717","article-title":"Modulation of cytokine production by carnitine","volume":"2","author":"Kouttab","year":"1993","journal-title":"Mediators Inflamm"},{"key":"10.1053\/j.jrn.2004.09.008_bib32","first-page":"938","article-title":"Can preoperative administration of carnitine avoid the cytokine promoted by CBP?","volume":"32","author":"Yilmaz","year":"1996","journal-title":"Isr J Med Sci"},{"key":"10.1053\/j.jrn.2004.09.008_bib33","series-title":"J Ren Nutr","article-title":"L-carnitine infusions may suppress serum C- reactive protein and improve nutritional status in maintenance hemodialysis patients","author":"Savica","year":"2005"},{"issue":"suppl 1","key":"10.1053\/j.jrn.2004.09.008_bib34","doi-asserted-by":"crossref","first-page":"S63","DOI":"10.1053\/ajkd.2001.27408","article-title":"Carnitine metabolism in uremia","volume":"38","author":"Guarnieri","year":"2001","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/j.jrn.2004.09.008_bib35","first-page":"P264A","article-title":"Effect of L-carnitine on nitrogen balance in CAPD patients","volume":"10","author":"Kopple","year":"1998","journal-title":"J Am Soc Nephrol"},{"key":"10.1053\/j.jrn.2004.09.008_bib36","first-page":"1","article-title":"Carnitine","volume":"89","author":"Peluso","year":"2000","journal-title":"J Cell Biochem"},{"key":"10.1053\/j.jrn.2004.09.008_bib37","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1159\/000183087","article-title":"Plasma and muscle carnitine levels in hemodialysis patients with morphological-ultrastructural examination of muscle samples","volume":"35","author":"Savica","year":"1983","journal-title":"Nephron"},{"key":"10.1053\/j.jrn.2004.09.008_bib38","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1097\/00002030-199202000-00011","article-title":"L-carnitine deficiency in AIDS patients","volume":"6","author":"De Simone","year":"1991","journal-title":"AIDS"},{"key":"10.1053\/j.jrn.2004.09.008_bib39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/08923979309066930","article-title":"High dose L-carnitine improves immunologic and metabolic parameters in AIDS patients","volume":"15","author":"De Simone","year":"1993","journal-title":"Immunopharmacol Immunotoxicol"}],"container-title":["Journal of Renal Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1051227604001657?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1051227604001657?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,2,2]],"date-time":"2024-02-02T05:18:36Z","timestamp":1706851116000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1051227604001657"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["S1051227604001657"],"URL":"https:\/\/doi.org\/10.1053\/j.jrn.2004.09.008","relation":{},"ISSN":["1051-2276"],"issn-type":[{"value":"1051-2276","type":"print"}],"subject":[],"published":{"date-parts":[[2005,1]]}}}