{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T13:37:10Z","timestamp":1760708230713},"reference-count":64,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2010,9,1]],"date-time":"2010-09-01T00:00:00Z","timestamp":1283299200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Renal Nutrition"],"published-print":{"date-parts":[[2010,9]]},"DOI":"10.1053\/j.jrn.2010.05.011","type":"journal-article","created":{"date-parts":[[2010,8,25]],"date-time":"2010-08-25T04:49:04Z","timestamp":1282711744000},"page":"S44-S50","source":"Crossref","is-referenced-by-count":12,"special_numbering":"S","title":["Mechanisms of Acute Uremic Encephalopathy: Early Activation of Fos and Fra-2 Gene Products in Different Nuclei\/Areas of the\u00a0Rat Brain"],"prefix":"10.1053","volume":"20","author":[{"given":"August","family":"Heidland","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katarina","family":"Sebekova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9","family":"Klassen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikl\u00f3s","family":"Palkovits","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1053\/j.jrn.2010.05.011_bib1","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1007\/s001340050487","article-title":"Epidemiology of acute renal failure and outcome of haemodiafiltration in intensive care","volume":"23","author":"Schwilk","year":"1997","journal-title":"Intensive Care Med"},{"key":"10.1053\/j.jrn.2010.05.011_bib2","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1097\/01.ASN.0000064946.94590.46","article-title":"Distant effects of experimental renal ischemia\/reperfusion injury","volume":"14","author":"Kelly","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"10.1053\/j.jrn.2010.05.011_bib3","doi-asserted-by":"crossref","first-page":"F30","DOI":"10.1152\/ajprenal.00023.2007","article-title":"Ischemic acute kidney injury induces a distant organ functional and genomic response distinguishable from bilateral nephrectomy","volume":"293","author":"Hassoun","year":"2007","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1053\/j.jrn.2010.05.011_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.clineuro.2004.07.012","article-title":"Neurological complications in renal failure: a review","volume":"107","author":"Brouns","year":"2004","journal-title":"Clin Neurol Neurosurg"},{"key":"10.1053\/j.jrn.2010.05.011_bib5","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1172\/JCI107984","article-title":"Changes in the electroencephalogram in acute uremia: effects of parathyroid hormone and brain electrolytes","volume":"55","author":"Guisado","year":"1975","journal-title":"J Clin Invest"},{"key":"10.1053\/j.jrn.2010.05.011_bib6","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1681\/ASN.2007080901","article-title":"Acute kidney injury leads to inflammation and functional changes in the brain","volume":"19","author":"Liu","year":"2008","journal-title":"J Am Soc Nephrol"},{"issue":"Suppl 78","key":"10.1053\/j.jrn.2010.05.011_bib7","doi-asserted-by":"crossref","first-page":"S77","DOI":"10.1046\/j.1523-1755.2001.59780077.x","article-title":"Endogenous guanidine compounds as uremic neurotoxins","volume":"59","author":"De Deyn","year":"2001","journal-title":"Kidney Int"},{"key":"10.1053\/j.jrn.2010.05.011_bib8","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1038\/sj.ki.5002513","article-title":"Accumulation of free adduct glycation, oxidation, and nitration products follows acute loss of renal function","volume":"72","author":"Rabbani","year":"2007","journal-title":"Kidney Int"},{"key":"10.1053\/j.jrn.2010.05.011_bib9","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1007\/s007020050108","article-title":"Cytotoxicity of advanced glycation end-products is mediated by oxidative stress","volume":"105","author":"Loske","year":"1998","journal-title":"J Neural Transm"},{"key":"10.1053\/j.jrn.2010.05.011_bib10","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.brainres.2006.06.038","article-title":"Susceptibility of brain microvascular endothelial cells to advanced glycation end product-induced tissue factor upregulation is associated with intracellular reactive oxygen species","volume":"1108","author":"Niiya","year":"2006","journal-title":"Brain Res"},{"key":"10.1053\/j.jrn.2010.05.011_bib11","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.1172\/JCI111920","article-title":"Abnormal sodium transport in synaptosomes from brain of uremic rats","volume":"75","author":"Fraser","year":"1985","journal-title":"J Clin Invest"},{"key":"10.1053\/j.jrn.2010.05.011_bib12","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1111\/j.1471-4159.2005.03550.x","article-title":"Involvement of organic anion transporters in the efflux of uremic toxins across the blood-brain barrier","volume":"96","author":"Deguchi","year":"2006","journal-title":"J Neurochem"},{"key":"10.1053\/j.jrn.2010.05.011_bib13","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/j.neuroscience.2008.12.062","article-title":"Neuronal activation in the CNS during different forms of acute renal failure in rats","volume":"159","author":"Palkovits","year":"2009","journal-title":"Neuroscience"},{"issue":"Suppl 87","key":"10.1053\/j.jrn.2010.05.011_bib14","doi-asserted-by":"crossref","first-page":"S105","DOI":"10.1046\/j.1523-1755.64.s87.16.x","article-title":"Obstructive nephropathy and renal fibrosis: the role of bone morphogenic protein-7 and hepatocyte growth factor","volume":"64","author":"Klahr","year":"2003","journal-title":"Kidney Int"},{"key":"10.1053\/j.jrn.2010.05.011_bib15","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1080\/01926230701748446","article-title":"Temporal clinical chemistry and microscopic renal effects following acute uranyl acetate exposure","volume":"35","author":"Zimmerman","year":"2007","journal-title":"Toxicol Pathol"},{"key":"10.1053\/j.jrn.2010.05.011_bib16","doi-asserted-by":"crossref","first-page":"3619","DOI":"10.1073\/pnas.87.9.3619","article-title":"Isolation and characterization of fra-2, an additional member of the fos gene family","volume":"87","author":"Nishina","year":"1990","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1053\/j.jrn.2010.05.011_bib17","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/S0165-0173(98)00018-6","article-title":"Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB\/ATF proteins","volume":"28","author":"Herdegen","year":"1998","journal-title":"Brain Res Rev"},{"key":"10.1053\/j.jrn.2010.05.011_bib18","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1038\/ki.1981.127","article-title":"Mechanisms of autonomic nervous system dysfunction in uremia","volume":"20","author":"Campese","year":"1981","journal-title":"Kidney Int"},{"key":"10.1053\/j.jrn.2010.05.011_bib19","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1161\/01.HYP.5.4.545","article-title":"Elevated plasma catecholamines in hypertensives with primary glomerular diseases","volume":"5","author":"Ishii","year":"1983","journal-title":"Hypertension"},{"key":"10.1053\/j.jrn.2010.05.011_bib20","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1159\/000412984","article-title":"Plasma catecholamines in renal failure","volume":"50","author":"Heidbreder","year":"1986","journal-title":"Contr Nephrol"},{"key":"10.1053\/j.jrn.2010.05.011_bib21","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1093\/ndt\/15.11.1735","article-title":"Sympathetic overactivity in renal disease: a window to understand progression and cardiovascular complications of uremia?","volume":"15","author":"Rump","year":"2000","journal-title":"Nephrol Dial Transplant"},{"key":"10.1053\/j.jrn.2010.05.011_bib22","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1097\/01.ASN.0000113320.57127.B9","article-title":"Sympathetic hyperactivity in chronic renal failure: a wake-up call","volume":"15","author":"Koomans","year":"2004","journal-title":"J Am Soc Nephrol"},{"key":"10.1053\/j.jrn.2010.05.011_bib23","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1053\/j.jrn.2007.10.024","article-title":"Sympathetic overactivity in uremia","volume":"18","author":"Ksiazek","year":"2008","journal-title":"J Renal Nutr"},{"key":"10.1053\/j.jrn.2010.05.011_bib24","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1139\/y81-199","article-title":"Altered concentration of catecholamines in the hypothalamus of the rat after renal denervation","volume":"59","author":"Calaresu","year":"1981","journal-title":"Can J Physiol Pharmacol"},{"key":"10.1053\/j.jrn.2010.05.011_bib25","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1681\/ASN.V4111901","article-title":"Altered norepinephrine turnover in the brain of rats with chronic renal failure","volume":"4","author":"Bigazzi","year":"1994","journal-title":"J Am Soc Nephrol"},{"key":"10.1053\/j.jrn.2010.05.011_bib26","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/0272-6386(95)90456-5","article-title":"Renal afferent denervation prevents the progression of renal disease in the renal ablation model of chronic renal failure in the rat","volume":"26","author":"Campese","year":"1995","journal-title":"Am J Kidney Dis"},{"issue":"Suppl 75","key":"10.1053\/j.jrn.2010.05.011_bib27","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1046\/j.1523-1755.2000.07511.x","article-title":"Neurogenic factors and hypertension in renal disease","volume":"57","author":"Campese","year":"2000","journal-title":"Kidney Int"},{"issue":"Suppl 1","key":"10.1053\/j.jrn.2010.05.011_bib28","doi-asserted-by":"crossref","first-page":"S74","DOI":"10.1053\/ajkd.2001.27409","article-title":"Effect of chronic renal failure on nitric oxide metabolism","volume":"38","author":"Vaziri","year":"2001","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/j.jrn.2010.05.011_bib29","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1046\/j.1523-1755.2000.00292.x","article-title":"Endothelial cell dysfunction and nitric oxide synthase","volume":"58","author":"Goligorsky","year":"2000","journal-title":"Kidney Int"},{"key":"10.1053\/j.jrn.2010.05.011_bib30","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1161\/01.HYP.0000049621.85474.CF","article-title":"Renal sympathetic nerve responses to tempol in spontaneously hypertensive rats","volume":"41","author":"Shokoji","year":"2003","journal-title":"Hypertension"},{"key":"10.1053\/j.jrn.2010.05.011_bib31","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1016\/0024-3205(85)90217-6","article-title":"Plasma and brain catecholamines in experimental uremia: acute and chronic studies","volume":"37","author":"Ali","year":"1985","journal-title":"Life Sci"},{"key":"10.1053\/j.jrn.2010.05.011_bib32","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1007\/s001340101067","article-title":"Uremia suppresses central dopaminergic metabolism and impairs motor activity in rats","volume":"27","author":"Adachi","year":"2001","journal-title":"Intense Care Med"},{"key":"10.1053\/j.jrn.2010.05.011_bib33","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/BF01252022","article-title":"Brain monoamines in metabolic (endotoxic) coma. A preliminary biochemical study in human post-mortem material","volume":"41","author":"Jellinger","year":"1977","journal-title":"J Neural Transm"},{"key":"10.1053\/j.jrn.2010.05.011_bib34","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1016\/j.neuro.2007.05.014","article-title":"Neurological effects of acute uranium exposure with and without stress","volume":"28","author":"Barber","year":"2007","journal-title":"Neurotoxicology"},{"key":"10.1053\/j.jrn.2010.05.011_bib35","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1093\/ajcn\/31.9.1665","article-title":"Increased histidine and histamine content in the brain of chronic uremic rats. Cause of enhanced cerebral cyclic adenosine monophosphate in uremia?","volume":"31","author":"Schmid","year":"1978","journal-title":"Am J Clin Nutr"},{"key":"10.1053\/j.jrn.2010.05.011_bib36","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.neuropharm.2007.04.001","article-title":"Highly activated c-fos expression in specific brain regions (ependyma, circumventricular organs, choroid plexus) of histidine decarboxylase deficient mice in response to formalin-induced acute pain","volume":"53","author":"Palkovits","year":"2007","journal-title":"Neuropharmacology"},{"key":"10.1053\/j.jrn.2010.05.011_bib37","first-page":"E526","article-title":"Brain serotonin turnover in chronically uremic rats","volume":"232","author":"Siassi","year":"1977","journal-title":"Am J Physiol"},{"key":"10.1053\/j.jrn.2010.05.011_bib38","first-page":"795","article-title":"Serotonin, a major player in the regulation of feeding and affect","volume":"44","author":"Casper","year":"1998","journal-title":"Biol Psychiatry"},{"key":"10.1053\/j.jrn.2010.05.011_bib39","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1056\/NEJMra041867","article-title":"The serotonin syndrome","volume":"352","author":"Boyer","year":"2005","journal-title":"New Engl J Med"},{"key":"10.1053\/j.jrn.2010.05.011_bib40","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1210\/er.22.4.502","article-title":"Stressor specificity of central neuroendocrine responses: implications for stress-related disorders","volume":"22","author":"Pacak","year":"2001","journal-title":"Endocr Rev"},{"key":"10.1053\/j.jrn.2010.05.011_bib41","series-title":"Stress, Neural, Endocrine and Molecular Studies","first-page":"25","article-title":"Pain and stress: convergence and divergence of neuronal pathways","author":"Palkovits","year":"2002"},{"key":"10.1053\/j.jrn.2010.05.011_bib42","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/0306-4522(94)90035-3","article-title":"Hindbrain structures involved in pain processing as revealed by the expression of c-Fos and other immediate early gene proteins","volume":"58","author":"Lant\u00e9ri-Minet","year":"1994","journal-title":"Neuroscience"},{"key":"10.1053\/j.jrn.2010.05.011_bib43","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1681\/ASN.2008040404","article-title":"Marconi revisited: from kidney to brain\u2014two organ systems communicating at long distance","volume":"19","author":"Vanholder","year":"2008","journal-title":"J Am Soc Nephrol"},{"key":"10.1053\/j.jrn.2010.05.011_bib44","doi-asserted-by":"crossref","first-page":"1912","DOI":"10.1056\/NEJM199212313272704","article-title":"Sympathetic overactivity in patients with chronic renal failure","volume":"327","author":"Converse","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1053\/j.jrn.2010.05.011_bib45","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1038\/ki.1997.103","article-title":"Renal afferent impulses, the posterior hypothalamus, and hypertension in rats with chronic renal failure","volume":"51","author":"Ye","year":"1997","journal-title":"Kidney Int"},{"key":"10.1053\/j.jrn.2010.05.011_bib46","first-page":"30","article-title":"Blood-brain barrier derangement in uremic encephalopathy","volume":"92","author":"Jeppsson","year":"1982","journal-title":"Surgery"},{"key":"10.1053\/j.jrn.2010.05.011_bib47","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/ki.1993.208","article-title":"Effect of ACE inhibitors on atrial natriuretic factor in the brain of rats with reduced renal mass","volume":"44","author":"Geiger","year":"1993","journal-title":"Kidney Int"},{"key":"10.1053\/j.jrn.2010.05.011_bib48","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1152\/physrev.1991.71.3.659","article-title":"Functional role of renal efferents","volume":"71","author":"Stella","year":"1991","journal-title":"Physiol Rev"},{"key":"10.1053\/j.jrn.2010.05.011_bib49","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1152\/physrev.1997.77.1.75","article-title":"Neural control of renal function","volume":"77","author":"Dibona","year":"1997","journal-title":"Physiol Rev"},{"key":"10.1053\/j.jrn.2010.05.011_bib50","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1002\/cne.903110309","article-title":"Sensory innervation of the rat kidney and ureter as revealed by the anterograde transport of wheat germ agglutinin-horseradish peroxidase (WGA-HRP) from dorsal root ganglia","volume":"311","author":"Marfurt","year":"1991","journal-title":"J Comp Neurol"},{"key":"10.1053\/j.jrn.2010.05.011_bib51","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0006-8993(98)00950-0","article-title":"The renal afferent pathways in the rat: a pseudorabies virus study","volume":"812","author":"Weiss","year":"1998","journal-title":"Brain Res"},{"key":"10.1053\/j.jrn.2010.05.011_bib52","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/0165-1838(83)90110-8","article-title":"Central projections of afferent renal fibers in the rat: an anterograde transport study of horseradish peroxidase","volume":"8","author":"Ciriello","year":"1983","journal-title":"J Auton Nerv Syst"},{"key":"10.1053\/j.jrn.2010.05.011_bib53","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/0361-9230(83)90168-5","article-title":"An analysis of the sensory innervation of the urinary system in the rat","volume":"11","author":"Donovan","year":"1983","journal-title":"Brain Res Bull"},{"key":"10.1053\/j.jrn.2010.05.011_bib54","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/0006-8993(84)91154-5","article-title":"A direct projection from the kidney to the brainstem","volume":"298","author":"Wyss","year":"1984","journal-title":"Brain Res"},{"key":"10.1053\/j.jrn.2010.05.011_bib55","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/0165-1838(86)90034-2","article-title":"Localization of sympathetic and sensory neurons innervating in the rat kidney","volume":"16","author":"Ferguson","year":"1986","journal-title":"J Auton Nerv Syst"},{"key":"10.1053\/j.jrn.2010.05.011_bib56","first-page":"F189","article-title":"Extrinsic innervation of the rat kidney: a retrograde tracing study","volume":"250","author":"Gattone","year":"1986","journal-title":"Am J Physiol"},{"key":"10.1053\/j.jrn.2010.05.011_bib57","first-page":"F957","article-title":"Cell of origin of the sympathetic renal innervation in rat","volume":"252","author":"Sripairojthikoon","year":"1987","journal-title":"Am J Physiol"},{"key":"10.1053\/j.jrn.2010.05.011_bib58","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0006-8993(93)90216-A","article-title":"Peripheral and central pathways regulating the kidney: a study using pseudorabies virus","volume":"616","author":"Schramm","year":"1993","journal-title":"Brain Res"},{"key":"10.1053\/j.jrn.2010.05.011_bib59","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0006-8993(99)01937-X","article-title":"Characterization of the central cell groups regulating the kidney in the rat","volume":"845","author":"Huang","year":"1999","journal-title":"Brain Res"},{"key":"10.1053\/j.jrn.2010.05.011_bib60","first-page":"277","article-title":"Neurochemical characterization of kidney regulating brainstem neurons identified by pseudorabies transneuronal labeling","volume":"8","author":"Reichart","year":"2000","journal-title":"Neurobiology"},{"key":"10.1053\/j.jrn.2010.05.011_bib61","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1146\/annurev.neuro.25.032502.111311","article-title":"The central autonomic nervous system: conscious visceral perception and autonomic pattern generation","volume":"25","author":"Saper","year":"2002","journal-title":"Annu Rev Neurosci"},{"key":"10.1053\/j.jrn.2010.05.011_bib62","doi-asserted-by":"crossref","first-page":"5694","DOI":"10.1523\/JNEUROSCI.14-09-05694.1994","article-title":"Afferents to the midline thalamus issue collaterals to the nucleus tractus solitarii: an anatomical basis for thalamic and visceral reflex integration","volume":"14","author":"Otake","year":"1994","journal-title":"J Neurosci"},{"key":"10.1053\/j.jrn.2010.05.011_bib63","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0006-8993(98)00442-9","article-title":"Visceral afferent pathways to the thalamus and olfactory tubercle: behavioral implications","volume":"799","author":"Ruggiero","year":"1998","journal-title":"Brain Res"},{"key":"10.1053\/j.jrn.2010.05.011_bib64","first-page":"R368","article-title":"Afferent nerve stimulation excites supraoptic vasopressin neurons","volume":"249","author":"Day","year":"1985","journal-title":"Am J Physiol"}],"container-title":["Journal of Renal Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1051227610001391?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1051227610001391?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,11,7]],"date-time":"2021-11-07T02:22:43Z","timestamp":1636251763000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1051227610001391"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9]]},"references-count":64,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,9]]}},"alternative-id":["S1051227610001391"],"URL":"https:\/\/doi.org\/10.1053\/j.jrn.2010.05.011","relation":{},"ISSN":["1051-2276"],"issn-type":[{"value":"1051-2276","type":"print"}],"subject":[],"published":{"date-parts":[[2010,9]]}}}