{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T22:55:37Z","timestamp":1767826537710,"version":"3.49.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Renal Nutrition"],"published-print":{"date-parts":[[2015,5]]},"DOI":"10.1053\/j.jrn.2014.09.007","type":"journal-article","created":{"date-parts":[[2014,11,6]],"date-time":"2014-11-06T17:50:08Z","timestamp":1415296208000},"page":"292-300","source":"Crossref","is-referenced-by-count":22,"title":["Plasma Ascorbic Acid Concentrations in Prevalent Patients With End-Stage Renal Disease on Hemodialysis"],"prefix":"10.1053","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6923-4081","authenticated-orcid":false,"given":"William D.","family":"Sirover","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuguan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Logan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krystal","family":"Hunter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert L.","family":"Benz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepali","family":"Prasad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose","family":"Avila","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thaliga","family":"Venkatchalam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence S.","family":"Weisberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Garry J.","family":"Handelman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1053\/j.jrn.2014.09.007_bib1","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/nrneph.2013.21","article-title":"Anaemia management and mortality risk in chronic kidney disease","volume":"9","author":"Horl","year":"2013","journal-title":"Nat Rev Nephrol"},{"key":"10.1053\/j.jrn.2014.09.007_bib2","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1038\/ki.2008.295","article-title":"Secondary analysis of the CHOIR trial epoetin-alpha dose and achieved hemoglobin outcomes","volume":"74","author":"Szczech","year":"2008","journal-title":"Kidney Int"},{"key":"10.1053\/j.jrn.2014.09.007_bib3","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1111\/j.1365-2141.1959.tb04020.x","article-title":"The enzymic formation of haem by the incorporation of iron into protoporphyrin; importance of ascorbic acid, ergothioneine and glutathione","volume":"5","author":"Goldberg","year":"1959","journal-title":"Br J Haematol"},{"key":"10.1053\/j.jrn.2014.09.007_bib4","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/j.1365-2141.1970.tb01624.x","article-title":"The relationship between serum ion levels and ascorbic acid stores in siderotic Bantu","volume":"19","author":"Wapnick","year":"1970","journal-title":"Br J Haematol"},{"key":"10.1053\/j.jrn.2014.09.007_bib5","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1080\/08860220802353884","article-title":"Beneficial hematologic effects of daily oral ascorbic acid therapy in ESRD patients with anemia and abnormal iron homeostasis: a preliminary study","volume":"30","author":"Sirover","year":"2008","journal-title":"Ren Fail"},{"key":"10.1053\/j.jrn.2014.09.007_bib6","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1046\/j.1523-1755.1999.00479.x","article-title":"Intravenous ascorbic acid as an adjuvant therapy for recombinant erythropoietin in hemodialysis patients with hyperferritinemia","volume":"55","author":"Tarng","year":"1999","journal-title":"Kidney Int"},{"issue":"Suppl 6","key":"10.1053\/j.jrn.2014.09.007_bib7","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1093\/ndt\/10.supp6.44","article-title":"Resistance to erythropoietin in iron-overloaded haemodialysis patients can be overcome by ascorbic acid administration","volume":"10","author":"Gastaldello","year":"1995","journal-title":"Nephrol Dial Transplant"},{"key":"10.1053\/j.jrn.2014.09.007_bib8","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1053\/j.ajkd.2005.12.025","article-title":"Effect of intravenous ascorbic acid in hemodialysis patients with EPO-hyporesponsive anemia and hyperferritinemia","volume":"47","author":"Attallah","year":"2006","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/j.jrn.2014.09.007_bib9","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1067\/msy.2002.122373","article-title":"Hemorrhage associated with vitamin C deficiency in surgical patients","volume":"131","author":"Blee","year":"2002","journal-title":"Surgery"},{"key":"10.1053\/j.jrn.2014.09.007_bib10","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/s12603-010-0032-y","article-title":"Scurvy in hospitalized elderly patients","volume":"14","author":"Raynaud-Simon","year":"2010","journal-title":"J Nutr Health Aging"},{"key":"10.1053\/j.jrn.2014.09.007_bib11","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1093\/ajcn\/24.4.444","article-title":"Metabolism of 14C- and 3H-labeled L-ascorbic acid in human scurvy","volume":"24","author":"Baker","year":"1971","journal-title":"Am J Clin Nutr"},{"key":"10.1053\/j.jrn.2014.09.007_bib12","doi-asserted-by":"crossref","first-page":"2319","DOI":"10.1093\/ndt\/gfh260","article-title":"Vitamin C plasma level and response to erythropoietin in patients on maintenance haemodialysis","volume":"19","author":"Deicher","year":"2004","journal-title":"Nephrol Dial Transplant"},{"key":"10.1053\/j.jrn.2014.09.007_bib13","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1093\/ajcn\/23.10.1339","article-title":"Ascorbic acid depletion in patients undergoing chronic hemodialysis","volume":"23","author":"Sullivan","year":"1970","journal-title":"Am J Clin Nutr"},{"key":"10.1053\/j.jrn.2014.09.007_bib14","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1159\/000070991","article-title":"Vitamin C in chronic kidney disease and hemodialysis patients","volume":"26","author":"Deicher","year":"2003","journal-title":"Kidney Blood Press Res"},{"key":"10.1053\/j.jrn.2014.09.007_bib15","doi-asserted-by":"crossref","first-page":"2058","DOI":"10.1093\/ndt\/gfn084","article-title":"Vitamin C deficiency and secondary hyperparathyroidism in chronic haemodialysis patients","volume":"23","author":"Richter","year":"2008","journal-title":"Nephrol Dial Transplant"},{"key":"10.1053\/j.jrn.2014.09.007_bib16","first-page":"262","article-title":"Vitamin C status of patients with chronic renal failure, dialysis patients and patients after renal transplantation","volume":"67","author":"Bohm","year":"1997","journal-title":"Int J Vitam Nutr Res"},{"key":"10.1053\/j.jrn.2014.09.007_bib17","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0272-6386(99)70259-3","article-title":"Acute-phase response predicts erythropoietin resistance in hemodialysis and peritoneal dialysis patients","volume":"33","author":"Gunnell","year":"1999","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/j.jrn.2014.09.007_bib18","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1007\/s002280050668","article-title":"Plasma ascorbic acid in patients undergoing chronic haemodialysis","volume":"55","author":"Wang","year":"1999","journal-title":"Eur J Clin Pharmacol"},{"key":"10.1053\/j.jrn.2014.09.007_bib19","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1093\/ndt\/gfl281","article-title":"Intestinal bacterial microflora\u2013a potential source of chronic inflammation in patients with chronic kidney disease","volume":"21","author":"Kotanko","year":"2006","journal-title":"Nephrol Dial Transplant"},{"key":"10.1053\/j.jrn.2014.09.007_bib20","doi-asserted-by":"crossref","first-page":"3704","DOI":"10.1073\/pnas.93.8.3704","article-title":"Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance","volume":"93","author":"Levine","year":"1996","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1053\/j.jrn.2014.09.007_bib21","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1038\/ki.2012.270","article-title":"Summary of the KDIGO guideline on anemia and comment: reading between the (guide)line(s)","volume":"82","author":"Drueke","year":"2012","journal-title":"Kidney Int"},{"key":"10.1053\/j.jrn.2014.09.007_bib22","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1093\/ndt\/gfm819","article-title":"Think of oxalate when using ascorbate supplementation to optimize iron therapy in dialysis patients","volume":"23","author":"Canavese","year":"2008","journal-title":"Nephrol Dial Transplant"},{"key":"10.1053\/j.jrn.2014.09.007_bib23","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1159\/000183353","article-title":"Vitamin C intoxication and hyperoxalemia in chronic hemodialysis patients","volume":"39","author":"Pru","year":"1985","journal-title":"Nephron"},{"key":"10.1053\/j.jrn.2014.09.007_bib24","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1001\/archopht.1989.01070020716035","article-title":"Retinal oxalosis. A clinicopathologic report","volume":"107","author":"Wells","year":"1989","journal-title":"Arch Ophthalmol"},{"key":"10.1053\/j.jrn.2014.09.007_bib25","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1038\/ki.1973.80","article-title":"Oxalosis as a complication of chronic renal failure","volume":"4","author":"Salyer","year":"1973","journal-title":"Kidney Int"},{"key":"10.1053\/j.jrn.2014.09.007_bib26","series-title":"Handbook of Dialysis","author":"Daugirdas","year":"2006"},{"key":"10.1053\/j.jrn.2014.09.007_bib27","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1081\/JDI-200049533","article-title":"Use of ascorbate-rich dialysate to attenuate oxidative stress in maintenance hemodialysis patients","volume":"27","author":"Shi","year":"2005","journal-title":"Ren Fail"},{"key":"10.1053\/j.jrn.2014.09.007_bib28","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1681\/ASN.V1121289","article-title":"Plasma oxalate levels rise in hemodialysis patients despite increased oxalate removal","volume":"1","author":"Costello","year":"1991","journal-title":"J Am Soc Nephrol"},{"key":"10.1053\/j.jrn.2014.09.007_bib29","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1053\/j.ajkd.2004.10.025","article-title":"Long-term, low-dose, intravenous vitamin C leads to plasma calcium oxalate supersaturation in hemodialysis patients","volume":"45","author":"Canavese","year":"2005","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/j.jrn.2014.09.007_bib30","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.bcmd.2010.11.004","article-title":"Anemia in older persons: etiology and evaluation","volume":"46","author":"Price","year":"2011","journal-title":"Blood Cells Mol Dis"},{"key":"10.1053\/j.jrn.2014.09.007_bib31","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1161\/01.CIR.103.14.1863","article-title":"Serum vitamin C concentration is low in peripheral arterial disease and is associated with inflammation and severity of atherosclerosis","volume":"103","author":"Langlois","year":"2001","journal-title":"Circulation"},{"key":"10.1053\/j.jrn.2014.09.007_bib32","doi-asserted-by":"crossref","first-page":"3810","DOI":"10.1182\/blood-2009-02-201087","article-title":"Proinflammatory state, hepcidin, and anemia in older persons","volume":"115","author":"Ferrucci","year":"2010","journal-title":"Blood"},{"key":"10.1053\/j.jrn.2014.09.007_bib33","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1089\/rej.2008.0787","article-title":"Ascorbate recycling by erythrocytes during aging in humans","volume":"12","author":"Rizvi","year":"2009","journal-title":"Rejuvenation Res"},{"key":"10.1053\/j.jrn.2014.09.007_bib34","doi-asserted-by":"crossref","first-page":"1960","DOI":"10.1046\/j.1523-1755.2001.0590051960.x","article-title":"Elevated plasma F2-isoprostanes in patients on long-term hemodialysis","volume":"59","author":"Handelman","year":"2001","journal-title":"Kidney Int"},{"key":"10.1053\/j.jrn.2014.09.007_bib35","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1093\/ndt\/18.2.326","article-title":"Anthropometric measures, cytokines and survival in haemodialysis patients","volume":"18","author":"Kimmel","year":"2003","journal-title":"Nephrol Dial Transplant"},{"key":"10.1053\/j.jrn.2014.09.007_bib36","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1053\/j.ajkd.2006.03.047","article-title":"Serum myeloperoxidase and mortality in maintenance hemodialysis patients","volume":"48","author":"Kalantar-Zadeh","year":"2006","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/j.jrn.2014.09.007_bib37","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1053\/j.ajkd.2006.02.190","article-title":"Enhanced expression of glucose transporter 1 on erythrocyte membrane in hemodialysis patients: the possible role in erythrocyte ascorbate recycling","volume":"47","author":"Wann","year":"2006","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/j.jrn.2014.09.007_bib38","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.1073\/pnas.88.6.2525","article-title":"The ubiquitous glucose transporter GLUT-1 belongs to the glucose-regulated protein family of stress-inducible proteins","volume":"88","author":"Wertheimer","year":"1991","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1053\/j.jrn.2014.09.007_bib39","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1681\/ASN.2007121313","article-title":"Proteinuria and hyperglycemia induce endoplasmic reticulum stress","volume":"19","author":"Lindenmeyer","year":"2008","journal-title":"J Am Soc Nephrol"},{"issue":"Suppl 1","key":"10.1053\/j.jrn.2014.09.007_bib40","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.2215\/CJN.01420406","article-title":"Acute injury with intravenous iron and concerns regarding long-term safety","volume":"1","author":"Bishu","year":"2006","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1053\/j.jrn.2014.09.007_bib41","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1093\/ndt\/gfh928","article-title":"Effects of oral vitamin C supplementation on oxidative stress and inflammation status in haemodialysis patients","volume":"20","author":"Fumeron","year":"2005","journal-title":"Nephrol Dial Transplant"},{"key":"10.1053\/j.jrn.2014.09.007_bib42","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1007\/s10534-012-9562-6","article-title":"Effect of intravenous vitamin C on cytokine activation and oxidative stress in end-stage renal disease patients receiving intravenous iron sucrose","volume":"25","author":"Conner","year":"2012","journal-title":"Biometals"},{"key":"10.1053\/j.jrn.2014.09.007_bib43","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.numecd.2005.11.011","article-title":"Erythrocyte transmembrane electron transfer in haemodialysis patients","volume":"17","author":"Matteucci","year":"2007","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"10.1053\/j.jrn.2014.09.007_bib44","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1161\/CIRCULATIONAHA.108.807362","article-title":"Fluid retention is associated with cardiovascular mortality in patients undergoing long-term hemodialysis","volume":"119","author":"Kalantar-Zadeh","year":"2009","journal-title":"Circulation"}],"container-title":["Journal of Renal Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1051227614001861?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1051227614001861?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,4,21]],"date-time":"2022-04-21T15:46:02Z","timestamp":1650555962000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1051227614001861"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5]]},"references-count":44,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["S1051227614001861"],"URL":"https:\/\/doi.org\/10.1053\/j.jrn.2014.09.007","relation":{},"ISSN":["1051-2276"],"issn-type":[{"value":"1051-2276","type":"print"}],"subject":[],"published":{"date-parts":[[2015,5]]}}}