{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T04:25:13Z","timestamp":1790223913142,"version":"4.1.0"},"reference-count":22,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2015,7,1]],"date-time":"2015-07-01T00:00:00Z","timestamp":1435708800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Disease","doi-asserted-by":"crossref","award":["K24 DK62849"],"award-info":[{"award-number":["K24 DK62849"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Disease","doi-asserted-by":"crossref","award":["5R01-AG031255"],"award-info":[{"award-number":["5R01-AG031255"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"crossref"}]},{"name":"National Institutes of Health\/National Institute on Aging"},{"name":"National Center for Advancing Translational Sciences of the National Institute of Health","award":["UL1-RR025764"],"award-info":[{"award-number":["UL1-RR025764"]}]},{"name":"National Center for Advancing Translational Sciences of the National Institute of Health","award":["1UL-1RR024975"],"award-info":[{"award-number":["1UL-1RR024975"]}]},{"name":"National Center for Advancing Translational Sciences of the National Institute of Health","award":["UL1 TR000445"],"award-info":[{"award-number":["UL1 TR000445"]}]},{"name":"National Center for Advancing Translational Sciences of the National Institute of Health","award":["C06-RR11234"],"award-info":[{"award-number":["C06-RR11234"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Renal Nutrition"],"published-print":{"date-parts":[[2015,7]]},"DOI":"10.1053\/j.jrn.2015.01.020","type":"journal-article","created":{"date-parts":[[2015,4,6]],"date-time":"2015-04-06T12:11:46Z","timestamp":1428322306000},"page":"371-375","source":"Crossref","is-referenced-by-count":33,"title":["Low Physical Function in Maintenance Hemodialysis Patients Is Independent of Muscle Mass and Comorbidity"],"prefix":"10.1053","volume":"25","author":[{"given":"Robin L.","family":"Marcus","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul C.","family":"LaStayo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. Alp","family":"Ikizler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Giri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaorui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glen","family":"Morrell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Painter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srinivasan","family":"Beddhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/j.jrn.2015.01.020_bib1","doi-asserted-by":"crossref","first-page":"M146","DOI":"10.1093\/gerona\/56.3.M146","article-title":"Frailty in older adults: evidence for a phenotype","volume":"56","author":"Fried","year":"2001","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"10.1053\/j.jrn.2015.01.020_bib2","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1001\/archinternmed.2012.3020","article-title":"Frailty, dialysis initiation, and mortality in end-stage renal disease","volume":"172","author":"Bao","year":"2012","journal-title":"Arch Intern Med"},{"key":"10.1053\/j.jrn.2015.01.020_bib3","doi-asserted-by":"crossref","first-page":"2960","DOI":"10.1681\/ASN.2007020221","article-title":"Significance of frailty among dialysis patients","volume":"18","author":"Johansen","year":"2007","journal-title":"J Am Soc Nephrol"},{"key":"10.1053\/j.jrn.2015.01.020_bib4","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.2215\/CJN.10261013","article-title":"Comparative associations of muscle mass and muscle strength with mortality in dialysis patients","volume":"9","author":"Isoyama","year":"2014","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1053\/j.jrn.2015.01.020_bib5","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1046\/j.1532-5415.2002.50216.x","article-title":"Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability","volume":"50","author":"Janssen","year":"2002","journal-title":"J Am Geriatr Soc"},{"key":"10.1053\/j.jrn.2015.01.020_bib6","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1002\/mrm.1910180211","article-title":"Three-point Dixon technique for true water\/fat decomposition with B0 inhomogeneity correction","volume":"18","author":"Glover","year":"1991","journal-title":"Magn Reson Med"},{"key":"10.1053\/j.jrn.2015.01.020_bib7","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1109\/83.382500","article-title":"Phase unwrapping of MR phase images using Poisson equation","volume":"4","author":"Moon-Ho Song","year":"1995","journal-title":"IEEE Trans Image Process"},{"key":"10.1053\/j.jrn.2015.01.020_bib8","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1002\/jmri.1880050311","article-title":"Proton MR spectroscopy in quantitative in\u00a0vivo determination of fat content in human liver steatosis","volume":"5","author":"Longo","year":"1995","journal-title":"J Magn Reson Imaging"},{"key":"10.1053\/j.jrn.2015.01.020_bib9","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1164\/ajrccm.166.1.at1102","article-title":"ATS statement: guidelines for the six-minute walk test","volume":"166","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1053\/j.jrn.2015.01.020_bib10","doi-asserted-by":"crossref","first-page":"2210","DOI":"10.1093\/ndt\/gfl064","article-title":"Patients receiving maintenance dialysis have more severe functionally significant skeletal muscle wasting than patients with dialysis-independent chronic kidney disease","volume":"21","author":"McIntyre","year":"2006","journal-title":"Nephrol Dial Transplant"},{"key":"10.1053\/j.jrn.2015.01.020_bib11","doi-asserted-by":"crossref","first-page":"E219","DOI":"10.1152\/ajpendo.2000.278.2.E219","article-title":"Reduced synthesis of muscle proteins in chronic renal failure","volume":"278","author":"Adey","year":"2000","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1053\/j.jrn.2015.01.020_bib12","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1681\/ASN.V84632","article-title":"Correction of acidosis in hemodialysis decreases whole-body protein degradation","volume":"8","author":"Graham","year":"1997","journal-title":"J Am Soc Nephrol"},{"key":"10.1053\/j.jrn.2015.01.020_bib13","doi-asserted-by":"crossref","first-page":"2366","DOI":"10.1097\/01.ASN.0000083905.72794.E6","article-title":"Effects of body size and body composition on survival in hemodialysis patients","volume":"14","author":"Beddhu","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"10.1053\/j.jrn.2015.01.020_bib14","doi-asserted-by":"crossref","first-page":"2258","DOI":"10.2215\/CJN.02080310","article-title":"Mid-arm muscle circumference and quality of life and survival in maintenance hemodialysis patients","volume":"5","author":"Noori","year":"2010","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1053\/j.jrn.2015.01.020_bib15","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.2215\/CJN.09200913","article-title":"Associations of body size and body composition with functional ability and quality of life in hemodialysis patients","volume":"9","author":"Martinson","year":"2014","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1053\/j.jrn.2015.01.020_bib16","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1093\/ndt\/gfh189","article-title":"Abnormal mitochondrial function and muscle wasting, but normal contractile efficiency, in haemodialysed patients studied non-invasively in\u00a0vivo","volume":"19","author":"Kemp","year":"2004","journal-title":"Nephrol Dial Transplant"},{"key":"10.1053\/j.jrn.2015.01.020_bib17","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1046\/j.1523-1755.2003.00739.x","article-title":"Impaired K+ regulation contributes to exercise limitation in end-stage renal failure","volume":"63","author":"Sangkabutra","year":"2003","journal-title":"Kidney Int"},{"key":"10.1053\/j.jrn.2015.01.020_bib18","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1093\/ndt\/gfg237","article-title":"Changes in muscle morphology in dialysis patients after 6 months of aerobic exercise training","volume":"18","author":"Sakkas","year":"2003","journal-title":"Nephrol Dial Transplant"},{"key":"10.1053\/j.jrn.2015.01.020_bib19","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s13539-011-0054-2","article-title":"Evolving concepts on the age-related changes in \u201cmuscle quality\u201d","volume":"3","author":"Russ","year":"2012","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"10.1053\/j.jrn.2015.01.020_bib20","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1093\/ndt\/12.1.119","article-title":"Physiological abnormalities of skeletal muscle in dialysis patients","volume":"12","author":"Fahal","year":"1997","journal-title":"Nephrol Dial Transplant"},{"key":"10.1053\/j.jrn.2015.01.020_bib21","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1378\/chest.123.2.387","article-title":"The 6-min walk test: a quick measure of functional status in elderly adults","volume":"123","author":"Enright","year":"2003","journal-title":"Chest"},{"key":"10.1053\/j.jrn.2015.01.020_bib22","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1164\/ajrccm.167.9.950","article-title":"ATS statement on six-minute walk test","volume":"167","author":"Brooks","year":"2003","journal-title":"Am J Respir Crit Care Med"}],"container-title":["Journal of Renal Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1051227615000436?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1051227615000436?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T12:09:51Z","timestamp":1651666191000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1051227615000436"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["S1051227615000436"],"URL":"https:\/\/doi.org\/10.1053\/j.jrn.2015.01.020","relation":{},"ISSN":["1051-2276"],"issn-type":[{"value":"1051-2276","type":"print"}],"subject":[],"published":{"date-parts":[[2015,7]]}}}