{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T02:45:26Z","timestamp":1779331526090,"version":"3.51.4"},"reference-count":44,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Medical Health and Science Development Project of Shandong Province","award":["2016ws0428"],"award-info":[{"award-number":["2016ws0428"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jrnjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Renal Nutrition"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1053\/j.jrn.2018.12.005","type":"journal-article","created":{"date-parts":[[2019,4,11]],"date-time":"2019-04-11T16:51:51Z","timestamp":1555001511000},"page":"386-393","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["High\u2013Resistant Starch, Low-Protein Flour Intervention on Patients With Early Type 2 Diabetic Nephropathy: A Randomized Trial"],"prefix":"10.1053","volume":"29","author":[{"given":"Yan","family":"Meng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Bai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingtao","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lili","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shijun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhaoping","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liyong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1053\/j.jrn.2018.12.005_bib1","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2013-002934","article-title":"Effect of low-protein diet on kidney function in diabetic nephropathy: meta-analysis of randomised controlled trials","volume":"3","author":"Nezu","year":"2013","journal-title":"BMJ Open"},{"key":"10.1053\/j.jrn.2018.12.005_bib2","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1046\/j.1523-1755.2003.00712.x","article-title":"Development and progression of nephropathy in type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS 64)","volume":"63","author":"Adler","year":"2003","journal-title":"Kidney Int"},{"key":"10.1053\/j.jrn.2018.12.005_bib3","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1053\/j.ajkd.2014.08.001","article-title":"Diabetic kidney disease: a report from an ADA Consensus Conference","volume":"64","author":"Tuttle","year":"2014","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/j.jrn.2018.12.005_bib4","article-title":"Molecular mechanisms of diabetic nephropathy and its therapeutic intervention","volume":"8","author":"Yamagishi","year":"2007","journal-title":"Curr Drug Targets"},{"key":"10.1053\/j.jrn.2018.12.005_bib5","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1038\/414813a","article-title":"Biochemistry and molecular cell biology of diabetic complications","volume":"414","author":"Brownlee","year":"2001","journal-title":"Nature"},{"key":"10.1053\/j.jrn.2018.12.005_bib6","first-page":"154","article-title":"Management of diabetic renal disease","volume":"3","author":"Eboh","year":"2015","journal-title":"Ann Translational Med"},{"key":"10.1053\/j.jrn.2018.12.005_bib7","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1046\/j.1523-1755.2002.00421.x","article-title":"Effect of dietary protein restriction on prognosis in patients with diabetic nephropathy","volume":"62","author":"Hansen","year":"2002","journal-title":"Kidney Int"},{"key":"10.1053\/j.jrn.2018.12.005_bib8","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1017\/S0007114509992820","article-title":"Postprandial glycaemic and insulinaemic responses to GM-resistant starch-enriched rice and the production of fermentation-related H2 in healthy Chinese adults","volume":"103","author":"Li","year":"2010","journal-title":"Br J Nutr"},{"key":"10.1053\/j.jrn.2018.12.005_bib9","doi-asserted-by":"crossref","first-page":"976","DOI":"10.2337\/dc05-2012","article-title":"Consumption of Both resistant starch and \u03b2-Glucan improves postprandial plasma glucose and insulin in Women","volume":"29","author":"Behall","year":"2006","journal-title":"Diabetes Care"},{"key":"10.1053\/j.jrn.2018.12.005_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1743-7075-1-8","article-title":"Resistant starch consumption promotes lipid oxidation","volume":"1","author":"Higgins","year":"2004","journal-title":"Nutr Metab"},{"key":"10.1053\/j.jrn.2018.12.005_bib11","first-page":"1","article-title":"Effects of a diet rich in arabinoxylan and resistant starch compared with a diet rich in refined carbohydrates on postprandial metabolism and features of the metabolic syndrome","volume":"57","author":"Schioldan","year":"2017","journal-title":"Eur J Nutr"},{"key":"10.1053\/j.jrn.2018.12.005_bib12","first-page":"H2550","article-title":"The effects of whole grain high-amylose maize flour as a source of resistant starch on blood glucose, satiety, and food intake in young men","volume":"79","author":"Luhovyy","year":"2015","journal-title":"J Food Sci"},{"key":"10.1053\/j.jrn.2018.12.005_bib13","doi-asserted-by":"crossref","first-page":"198","DOI":"10.3945\/an.114.007419","article-title":"Role of resistant starch in improving gut health, Adiposity, and insulin resistance","volume":"6","author":"Keenan","year":"2015","journal-title":"Adv Nutr"},{"key":"10.1053\/j.jrn.2018.12.005_bib14","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1017\/S0007114514002177","article-title":"Potential of novel dextran oligosaccharides as prebiotics for obesity management through in\u00a0vitro experimentation","volume":"112","author":"Sarbini","year":"2014","journal-title":"Br J Nutr"},{"key":"10.1053\/j.jrn.2018.12.005_bib15","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1007\/s00394-015-1138-0","article-title":"Resistant starch for modulation of gut microbiota: Promising adjuvant therapy for chronic kidney disease patients?","volume":"55","author":"Moraes","year":"2016","journal-title":"Eur J Nutr"},{"key":"10.1053\/j.jrn.2018.12.005_bib16","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1093\/ajcn\/61.1.75","article-title":"Influence of the physical form of barley grain on the digestion of its starch in the human small intestine and implications for health","volume":"61","author":"Livesey","year":"1995","journal-title":"Am J Clin Nutr"},{"key":"10.1053\/j.jrn.2018.12.005_bib17","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1038\/ki.2011.355","article-title":"High dietary fiber intake is associated with decreased inflammation and all-cause mortality in patients with chronic kidney disease","volume":"81","author":"Krishnamurthy","year":"2012","journal-title":"Kidney Int"},{"key":"10.1053\/j.jrn.2018.12.005_bib18","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1038\/ejcn.2014.237","article-title":"Dietary fiber effects in chronic kidney disease: a systematic review and meta-analysis of controlled feeding trials","volume":"69","author":"Chiavaroli","year":"2015","journal-title":"Eur J Clin Nutr"},{"key":"10.1053\/j.jrn.2018.12.005_bib19","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1053\/j.jrn.2005.10.007","article-title":"Fermentable carbohydrate supplementation alters nitrogen excretion in chronic renal failure","volume":"16","author":"Demign\u00e9","year":"2006","journal-title":"J Ren Nutr"},{"key":"10.1053\/j.jrn.2018.12.005_bib20","first-page":"51","article-title":"How to calculate sample size in randomized controlled trial?","volume":"1","author":"Zhong","year":"2009","journal-title":"J Thorac Dis"},{"key":"10.1053\/j.jrn.2018.12.005_bib21","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1007\/BF00400359","article-title":"UK prospective diabetes study (UKPDS)","volume":"36","year":"1993","journal-title":"Diabetologia"},{"key":"10.1053\/j.jrn.2018.12.005_bib22","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1146\/annurev.med.46.1.79","article-title":"Management of early nephropathy in diabetic patients","volume":"46","author":"Mogensen","year":"1995","journal-title":"Annu Rev Med"},{"key":"10.1053\/j.jrn.2018.12.005_bib23","first-page":"1","article-title":"Managing diabetic kidney disease","author":"Zac-Varghese","year":"2017","journal-title":"British Medical Bulletin"},{"key":"10.1053\/j.jrn.2018.12.005_bib24","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1093\/ajcn\/60.4.544","article-title":"Resistant starch: the effect on postprandial glycemia, hormonal response, and satiety","volume":"60","author":"Raben","year":"1994","journal-title":"Am J Clin Nutr"},{"key":"10.1053\/j.jrn.2018.12.005_bib25","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1152\/physrev.2001.81.3.1031","article-title":"Short-chain fatty acids and human colonic function: roles of resistant starch and Nonstarch Polysaccharides","volume":"81","author":"Topping","year":"2001","journal-title":"Physiol Rev"},{"key":"10.1053\/j.jrn.2018.12.005_bib26","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.2337\/db05-1620","article-title":"Risk factors for renal dysfunction in type 2 diabetes: U.K. Prospective Diabetes Study 74","volume":"55","author":"Retnakaran","year":"2006","journal-title":"Diabetes"},{"key":"10.1053\/j.jrn.2018.12.005_bib27","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1007\/s10157-013-0880-y","article-title":"Abnormal lipoprotein metabolism in diabetic nephropathy","volume":"18","author":"Hirano","year":"2014","journal-title":"Clin Exp Nephrol"},{"key":"10.1053\/j.jrn.2018.12.005_bib28","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.2337\/diacare.21.11.2016","article-title":"Decreased release of lipoprotein lipase is associated with vascular endothelial damage in NIDDM patients with microalbuminuria","volume":"21","author":"Kashiwazaki","year":"1998","journal-title":"Diabetes Care"},{"key":"10.1053\/j.jrn.2018.12.005_bib29","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1007\/s11745-003-1145-2","article-title":"Enzyme-resistant fractions of beans lowered serum cholesterol and increased sterol excretions and hepatic mRNA levels in rats","volume":"38","author":"Han","year":"2003","journal-title":"Lipids"},{"key":"10.1053\/j.jrn.2018.12.005_bib30","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1093\/jn\/131.4.1283","article-title":"Class 2 resistant starches lower plasma and liver lipids and improve mineral retention in rats","volume":"131","author":"Lopez","year":"2001","journal-title":"J Nutr"},{"key":"10.1053\/j.jrn.2018.12.005_bib31","first-page":"4238","article-title":"Effect of starch malabsorption on fecal bile acids and neutral sterols in humans: possible implications for colonic carcinogenesis","volume":"51","author":"Bartram","year":"1991","journal-title":"Cancer Res"},{"key":"10.1053\/j.jrn.2018.12.005_bib32","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1093\/jn\/129.5.942","article-title":"Short-chain fatty acids suppress\u00a0cholesterol synthesis in rat liver and intestine","volume":"129","author":"Hara","year":"1999","journal-title":"J Nutr"},{"key":"10.1053\/j.jrn.2018.12.005_bib33","doi-asserted-by":"crossref","first-page":"761","DOI":"10.2337\/diab.39.7.761","article-title":"Prediction of clinical diabetic nephropathy in IDDM patients. Alternatives to microalbuminuria?","volume":"39","author":"Mogensen","year":"1990","journal-title":"Diabetes"},{"key":"10.1053\/j.jrn.2018.12.005_bib34","doi-asserted-by":"crossref","first-page":"736","DOI":"10.2337\/diab.41.6.736","article-title":"Prospective study of microalbuminuria as Predictor of mortality in NIDDM","volume":"41","author":"Mattock","year":"1992","journal-title":"Diabetes"},{"key":"10.1053\/j.jrn.2018.12.005_bib35","article-title":"Intensive blood-glucose control with sulfonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)","volume":"352","year":"1998","journal-title":"Lancet"},{"key":"10.1053\/j.jrn.2018.12.005_bib36","series-title":"Chronic Kidney Disease (Partial Update): Early Identification and Management of Chronic Kidney Disease in Adults in Primary and Secondary Care","year":"2014"},{"key":"10.1053\/j.jrn.2018.12.005_bib37","first-page":"RA37","article-title":"Role of oxidative stress in diabetic kidney disease","volume":"16","author":"Hakim","year":"2010","journal-title":"Med Sci Monitor"},{"key":"10.1053\/j.jrn.2018.12.005_bib38","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1111\/j.1523-1755.2005.00274.x","article-title":"Reactive oxygen species mediate\u00a0high glucose-induced plasminogen activator inhibitor-1 up-regulation\u00a0in mesangial cells and in diabetic kidney","volume":"67","author":"Lee","year":"2005","journal-title":"Kidney Int"},{"key":"10.1053\/j.jrn.2018.12.005_bib39","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1038\/nrendo.2010.212","article-title":"Oxidative stress in early diabetic nephropathy: fueling the fire","volume":"7","author":"Singh","year":"2011","journal-title":"Nat Rev Endocrinol"},{"key":"10.1053\/j.jrn.2018.12.005_bib40","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.atherosclerosis.2012.08.003","article-title":"Dietary treatment with rice containing resistant starch improves markers of endothelial function with reduction of postprandial blood glucose and oxidative stress in patients with prediabetes or newly diagnosed type 2 diabetes","volume":"224","author":"Kwak","year":"2012","journal-title":"Atherosclerosis"},{"key":"10.1053\/j.jrn.2018.12.005_bib41","doi-asserted-by":"crossref","first-page":"e114881","DOI":"10.1371\/journal.pone.0114881","article-title":"High amylose resistant starch diet Ameliorates oxidative stress, inflammation, and progression of chronic kidney disease","volume":"9","author":"Vaziri","year":"2014","journal-title":"Plos One"},{"key":"10.1053\/j.jrn.2018.12.005_bib42","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1681\/ASN.2007091048","article-title":"The role of inflammatory cytokines in diabetic nephropathy","volume":"19","author":"Navarro-Gonz\u00e1lez","year":"2008","journal-title":"J Am Soc Nephrol Jasn"},{"key":"10.1053\/j.jrn.2018.12.005_bib43","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1093\/ndt\/gfm674","article-title":"Influence of renal involvement on peripheral blood mononuclear cell expression behaviour of tumour necrosis factor-\u03b1 and interleukin-6 in type 2 diabetic patients","volume":"23","author":"Navarro","year":"2008","journal-title":"Nephrology, Dialysis, Transplantation: Official Publication Eur Dial Transpl Assoc - Eur Ren Assoc"},{"key":"10.1053\/j.jrn.2018.12.005_bib44","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1111\/hdi.12653","article-title":"Effect of high amylose resistant starch (HAM-RS2) supplementation on biomarkers of inflammation and oxidative stress in hemodialysis patients: a randomized clinical trial","volume":"22","author":"Tayebi","year":"2018","journal-title":"Hemodialysis Int"}],"container-title":["Journal of Renal Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1051227618302863?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1051227618302863?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T06:33:32Z","timestamp":1760942012000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1051227618302863"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":44,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["S1051227618302863"],"URL":"https:\/\/doi.org\/10.1053\/j.jrn.2018.12.005","relation":{},"ISSN":["1051-2276"],"issn-type":[{"value":"1051-2276","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"High\u2013Resistant Starch, Low-Protein Flour Intervention on Patients With Early Type 2 Diabetic Nephropathy: A Randomized Trial","name":"articletitle","label":"Article Title"},{"value":"Journal of Renal Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.jrn.2018.12.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier Inc. on behalf of the National Kidney Foundation, Inc.","name":"copyright","label":"Copyright"}]}}