{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T03:53:46Z","timestamp":1772250826909,"version":"3.50.1"},"reference-count":16,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jcardioanesthesia.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiothoracic and Vascular Anesthesia"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1053\/j.jvca.2019.08.013","type":"journal-article","created":{"date-parts":[[2019,8,17]],"date-time":"2019-08-17T01:47:08Z","timestamp":1566006428000},"page":"3402-3405","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Elevated Serum Cobalt Concentrations Associated With Hydroxocobalamin Administration for Refractory Vasoplegia"],"prefix":"10.1053","volume":"33","author":[{"given":"Troy G.","family":"Seelhammer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Charnin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanjun","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erica","family":"Wittwer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua","family":"Bornhorst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1053\/j.jvca.2019.08.013_bib0001","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.tox.2017.05.015","article-title":"Cobalt toxicity in humans-A review of the potential sources and systemic health effects","volume":"387","author":"Leyssens","year":"2017","journal-title":"Toxicology"},{"key":"10.1053\/j.jvca.2019.08.013_bib0002","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s13181-013-0347-2","article-title":"Current use of chelation in American health care","volume":"9","author":"Wax","year":"2013","journal-title":"J Med Toxicol"},{"key":"10.1053\/j.jvca.2019.08.013_bib0003","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/j.1600-0773.1953.tb02954.x","article-title":"The effect of cobalt on blood pressure, respiration and mortality, and the use of dimercaprol (BAL) as antidote","volume":"9","author":"Dalhamn","year":"1953","journal-title":"Acta Pharmacol Toxicol (Copenh)"},{"key":"10.1053\/j.jvca.2019.08.013_bib0004","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s13181-013-0343-6","article-title":"The role of chelation in the treatment of other metal poisonings","volume":"9","author":"Smith","year":"2013","journal-title":"J Med Toxicol"},{"key":"10.1053\/j.jvca.2019.08.013_bib0005","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1007\/BF01720716","article-title":"Hydroxocobalamin vs cobalt toxicity on rat cardiac and diaphragmatic muscles","volume":"22","author":"Pery-Man","year":"1996","journal-title":"Intensive Care Med"},{"key":"10.1053\/j.jvca.2019.08.013_bib0006","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1053\/j.jvca.2018.08.017","article-title":"Hydroxocobalamin for the treatment of vasoplegia: A review of current literature and considerations for use","volume":"33","author":"Shapeton","year":"2019","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10.1053\/j.jvca.2019.08.013_bib0007","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.clnu.2011.08.010","article-title":"Increased vitamin B12 levels are associated with mortality in critically ill medical patients","volume":"31","author":"Sviri","year":"2012","journal-title":"Clin Nutr"},{"key":"10.1053\/j.jvca.2019.08.013_bib0008","unstructured":"US National Library of Medicine. Cyanokit. Available at: https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/44475014. Accessed June 3, 2019."},{"key":"10.1053\/j.jvca.2019.08.013_bib0009","series-title":"Mayo Medical Laboratories interpretive handbook: Interpretive data for diagnostic laboratory tests","year":"2001"},{"key":"10.1053\/j.jvca.2019.08.013_bib0010","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/8274504","article-title":"Rationale for the successful management of EDTA chelation therapy in human burden by toxic metals","volume":"2016","author":"Ferrero","year":"2016","journal-title":"Biomed Res Int"},{"key":"10.1053\/j.jvca.2019.08.013_bib0011","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.scitotenv.2012.06.009","article-title":"Cobalt metabolism and toxicology\u2014a brief update","volume":"432","author":"Simonsen","year":"2012","journal-title":"Sci Total Environ"},{"key":"10.1053\/j.jvca.2019.08.013_bib0012","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1002\/jbm.a.32627","article-title":"Soluble ions more than particulate cobalt-alloy implant debris induce monocyte costimulatory molecule expression and release of proinflammatory cytokines critical to metal-induced lymphocyte reactivity","volume":"93","author":"Caicedo","year":"2010","journal-title":"J Biomed Mater Res A"},{"key":"10.1053\/j.jvca.2019.08.013_bib0013","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1093\/ckj\/sfx004","article-title":"High-dose hydroxocobalamin for vasoplegic syndrome causing false blood leak alarm","volume":"10","author":"Cheungpasitporn","year":"2017","journal-title":"Clin Kidney J"},{"key":"10.1053\/j.jvca.2019.08.013_bib0014","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1213\/ANE.0000000000003648","article-title":"Use of hydroxocobalamin (vitamin B12a) in patients with vasopressor refractory hypotension after cardiopulmonary bypass: A case series","volume":"129","author":"Armour","year":"2019","journal-title":"Anesth Analg"},{"key":"10.1053\/j.jvca.2019.08.013_bib0015","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1007\/s00134-016-4252-4","article-title":"Risk of oxalate nephropathy with the use of cyanide antidote hydroxocobalamin in critically ill burn patients","volume":"42","author":"Legrand","year":"2016","journal-title":"Intensive Care Med"},{"key":"10.1053\/j.jvca.2019.08.013_bib0016","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.chest.2017.12.021","article-title":"Management of refractory vasodilatory shock","volume":"154","author":"Jentzer","year":"2018","journal-title":"Chest"}],"container-title":["Journal of Cardiothoracic and Vascular Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S105307701930878X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S105307701930878X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T07:44:02Z","timestamp":1760946242000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S105307701930878X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":16,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["S105307701930878X"],"URL":"https:\/\/doi.org\/10.1053\/j.jvca.2019.08.013","relation":{},"ISSN":["1053-0770"],"issn-type":[{"value":"1053-0770","type":"print"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Elevated Serum Cobalt Concentrations Associated With Hydroxocobalamin Administration for Refractory Vasoplegia","name":"articletitle","label":"Article Title"},{"value":"Journal of Cardiothoracic and Vascular Anesthesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.jvca.2019.08.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1053\/j.jvca.2019.08.033","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}