{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T06:44:38Z","timestamp":1792651478195,"version":"4.5.0"},"reference-count":48,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jcardioanesthesia.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiothoracic and Vascular Anesthesia"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1053\/j.jvca.2021.02.007","type":"journal-article","created":{"date-parts":[[2021,2,8]],"date-time":"2021-02-08T01:45:00Z","timestamp":1612748700000},"page":"1792-1799","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Monitoring of the Progression of the Perioperative Serum Lactate Concentration Improves the Accuracy of the Prediction of Acute Mesenteric Ischemia Development After Cardiovascular Surgery"],"prefix":"10.1053","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3686-6116","authenticated-orcid":false,"given":"Henning","family":"Mothes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Wickel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Sponholz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Lehmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirko","family":"Kaluza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juergen","family":"Zanow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torsten","family":"Doenst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/j.jvca.2021.02.007_bib0001","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1007\/s00380-019-01531-w","article-title":"Clinical features and outcomes of nonocclusive mesenteric ischemia after cardiac surgery: A retrospective cohort study","volume":"35","author":"Sakamoto","year":"2020","journal-title":"Heart Vessels"},{"key":"10.1053\/j.jvca.2021.02.007_bib0002","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1007\/s00268-005-0560-5","article-title":"Identification of risk factors for perioperative mortality in acute mesenteric ischemia","volume":"30","author":"Acosta-Merida","year":"2006","journal-title":"World J Surg"},{"key":"10.1053\/j.jvca.2021.02.007_bib0003","first-page":"148","article-title":"Ist ein Mesenterialinfarkt nach kardio-chirurgischen Eingriffen vermeidbar?","volume":"18","author":"Luther","year":"2004","journal-title":"Zeitschrift Herz-, Thorax- und Gef\u00e4\u00dfchirurgie"},{"key":"10.1053\/j.jvca.2021.02.007_bib0004","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1016\/S0003-4975(01)03179-4","article-title":"Diagnosis and treatment of nonocclusive mesenteric ischemia after open heart surgery","volume":"72","author":"Klotz","year":"2001","journal-title":"Ann Thorac Surg"},{"key":"10.1053\/j.jvca.2021.02.007_bib0005","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.jcrc.2017.08.018","article-title":"Risk factors for postoperative acute mesenteric ischemia among adult patients undergoing cardiac surgery: A systematic review and meta-analysis","volume":"42","author":"Deng","year":"2017","journal-title":"J Crit Care"},{"key":"10.1053\/j.jvca.2021.02.007_bib0006","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1093\/icvts\/ivu145","article-title":"Is it possible to predict the risk of ischaemic bowel after cardiac surgery?","volume":"19","author":"Yap","year":"2014","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"10.1053\/j.jvca.2021.02.007_bib0007","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.surg.2010.11.008","article-title":"Ischemic colitis: Who will survive?","volume":"149","author":"Reissfelder","year":"2011","journal-title":"Surg"},{"key":"10.1053\/j.jvca.2021.02.007_bib0008","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1177\/0310057X0503300209","article-title":"Diagnosis and outcome from suspected mesenteric ischaemia following cardiac surgery","volume":"33","author":"Edwards","year":"2005","journal-title":"Anaesth Intensive Care"},{"key":"10.1053\/j.jvca.2021.02.007_bib0009","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/S1010-7940(02)00762-5","article-title":"Off-pump coronary artery bypass surgery does not reduce gastrointestinal complications","volume":"23","author":"Musleh","year":"2003","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1053\/j.jvca.2021.02.007_bib0010","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/S1010-7940(02)00373-1","article-title":"Lethal mesenteric ischaemia after cardiopulmonary bypass: A common complication?","volume":"22","author":"Venkateswaran","year":"2002","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1053\/j.jvca.2021.02.007_bib0011","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/0741-5214(92)90372-F","article-title":"Acute mesenteric ischemia after cardiopulmonary bypass","volume":"16","author":"Allen","year":"1992","journal-title":"J Vasc Surg"},{"key":"10.1053\/j.jvca.2021.02.007_bib0012","series-title":"1: N Matching von F\u00e4llen und Kontrollen: Propensity score vs","author":"Deckert","year":"2011"},{"key":"10.1053\/j.jvca.2021.02.007_bib0013","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1093\/oxfordjournals.aje.a116398","article-title":"Selection of controls in case-control studies. III. Design options","volume":"135","author":"Wacholder","year":"1992","journal-title":"Am J Epidemiol"},{"key":"10.1053\/j.jvca.2021.02.007_bib0014","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1016\/j.jtcvs.2012.11.022","article-title":"Risk factors for nonocclusive mesenteric ischemia after elective cardiac surgery","volume":"45","author":"Groesdonk","year":"2013","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1053\/j.jvca.2021.02.007_bib0015","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.surg.2003.12.019","article-title":"A simple but useful method of screening for mesenteric ischemia secondary to acute aortic dissection","volume":"136","author":"Kurimoto","year":"2004","journal-title":"Surgery"},{"key":"10.1053\/j.jvca.2021.02.007_bib0016","doi-asserted-by":"crossref","first-page":"114","DOI":"10.2310\/6670.2004.20769","article-title":"Clinically diagnosed nonocclusive mesenteric ischemia after cardiopulmonary bypass: Retrospective study","volume":"12","author":"Huwer","year":"2004","journal-title":"Vascular"},{"key":"10.1053\/j.jvca.2021.02.007_bib0017","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.ijsu.2015.12.066","article-title":"Acute mesenteric ischemia following cardiovascular surgery - a nested case-control study","volume":"26","author":"Mothes","year":"2016","journal-title":"Int J Surg"},{"key":"10.1053\/j.jvca.2021.02.007_bib0018","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.bpg.2017.01.004","article-title":"Serological markers for human intestinal ischemia: A systematic review","volume":"31","author":"Derikx","year":"2017","journal-title":"Best Pract Res Clin Gastroenterol"},{"key":"10.1053\/j.jvca.2021.02.007_bib0019","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.jtcvs.2012.03.014","article-title":"Endothelin and vasopressin influence splanchnic blood flow distribution during and after cardiopulmonary bypass","volume":"145","author":"Bomberg","year":"2013","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1053\/j.jvca.2021.02.007_bib0020","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1007\/s00268-009-0074-7","article-title":"Systematic review and pooled estimates for the diagnostic accuracy of serological markers for intestinal ischemia","volume":"33","author":"Evennett","year":"2009","journal-title":"World J Surg"},{"key":"10.1053\/j.jvca.2021.02.007_bib0021","doi-asserted-by":"crossref","first-page":"R25","DOI":"10.1186\/cc8888","article-title":"Relative hyperlactatemia and hospital mortality in critically ill patients: A retrospective multi-centre study","volume":"14","author":"Nichol","year":"2010","journal-title":"Crit Care"},{"key":"10.1053\/j.jvca.2021.02.007_bib0022","doi-asserted-by":"crossref","first-page":"R90","DOI":"10.1186\/cc7918","article-title":"Occurrence and adverse effect on outcome of hyperlactatemia in the critically ill","volume":"13","author":"Khosravani","year":"2009","journal-title":"Crit Care"},{"key":"10.1053\/j.jvca.2021.02.007_bib0023","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1007\/s001340051352","article-title":"Base excess and lactate as prognostic indicators for patients admitted to intensive care","volume":"27","author":"Smith","year":"2001","journal-title":"Intensive Care Med"},{"key":"10.1053\/j.jvca.2021.02.007_bib0024","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1378\/chest.123.5.1361","article-title":"Frequency, risk factors, and outcome of hyperlactatemia after cardiac surgery","volume":"123","author":"Maillet","year":"2003","journal-title":"Chest"},{"key":"10.1053\/j.jvca.2021.02.007_bib0025","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1038\/ajg.2017.38","article-title":"Predictive factors of intestinal necrosis in acute mesenteric ischemia: Prospective study from an intestinal stroke center","volume":"112","author":"Nuzzo","year":"2017","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/j.jvca.2021.02.007_bib0026","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1016\/S0003-4975(00)02160-3","volume":"7","author":"Demers","year":"2000","journal-title":"Ann Thorac Surg"},{"key":"10.1053\/j.jvca.2021.02.007_bib0027","first-page":"63","article-title":"Hyperlactacidemia in intestinal ischemia. I. Theoretical considerations","volume":"370","author":"Nutz","year":"1987","journal-title":"Langenbecks Arch Surg"},{"key":"10.1053\/j.jvca.2021.02.007_bib0028","article-title":"Two-hour lactate clearance predicts negative outcome in patients with cardiorespiratory insufficiency","volume":"2010","author":"Scott","year":"2010","journal-title":"Crit Care Res Pract"},{"key":"10.1053\/j.jvca.2021.02.007_bib0029","doi-asserted-by":"crossref","first-page":"R160","DOI":"10.1186\/cc7159","article-title":"The prognostic value of blood lactate levels relative to that of vital signs in the pre-hospital setting: A pilot study","volume":"12","author":"Jansen","year":"2008","journal-title":"Crit Care"},{"key":"10.1053\/j.jvca.2021.02.007_bib0030","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1097\/01.CCM.0000132904.35713.A7","article-title":"Early lactate clearance is associated with improved outcome in severe sepsis and septic shock","volume":"32","author":"Nguyen","year":"2004","journal-title":"Crit Care Med"},{"key":"10.1053\/j.jvca.2021.02.007_bib0031","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0002-9610(97)89552-9","article-title":"Serial blood lactate levels can predict the development of multiple organ failure following septic shock","volume":"171","author":"Bakker","year":"1996","journal-title":"Am J Surg"},{"key":"10.1053\/j.jvca.2021.02.007_bib0032","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1378\/chest.99.4.956","article-title":"Blood lactate levels are superior to oxygen-derived variables in predicting outcome in human septic shock","volume":"99","author":"Bakker","year":"1991","journal-title":"Chest"},{"key":"10.1053\/j.jvca.2021.02.007_bib0033","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1053\/j.jvca.2019.10.039","article-title":"Evaluation of increase in intraoperative lactate level as a predictor of outcome in adults after cardiac surgery","volume":"34","author":"Govender","year":"2020","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10.1053\/j.jvca.2021.02.007_bib0034","first-page":"115","article-title":"Lactate and lactate clearance in acute cardiac care patients","volume":"1","author":"Attana","year":"2012","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"10.1053\/j.jvca.2021.02.007_bib0035","doi-asserted-by":"crossref","first-page":"R167","DOI":"10.1186\/cc5113","article-title":"Hyperlactatemia during cardiopulmonary bypass: Determinants and impact on postoperative outcome","volume":"10","author":"Ranucci","year":"2006","journal-title":"Crit Care"},{"key":"10.1053\/j.jvca.2021.02.007_bib0036","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1007\/s00134-003-1860-6","article-title":"Effect of cardiopulmonary bypass on lactate metabolism","volume":"29","author":"Mustafa","year":"2003","journal-title":"Intensive Care Med"},{"key":"10.1053\/j.jvca.2021.02.007_bib0037","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1053\/j.jvca.2019.11.049","article-title":"Elevation of intraoperative lactate levels during cardiac surgery: Is there power in this prognostication?","volume":"34","author":"Cotter","year":"2020","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10.1053\/j.jvca.2021.02.007_bib0038","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1177\/0267659119855857","article-title":"Intraoperative changes in blood lactate levels are associated with worse short-term outcomes after cardiac surgery with cardiopulmonary bypass","volume":"34","author":"Duval","year":"2019","journal-title":"Perfusion"},{"key":"10.1053\/j.jvca.2021.02.007_bib0039","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.jtcvs.2013.02.003","article-title":"High lactate levels are predictors of major complications after cardiac surgery","volume":"146","author":"Hajjar","year":"2013","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1053\/j.jvca.2021.02.007_bib0040","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1007\/s00540-011-1287-0","article-title":"The impact of hyperlactatemia on postoperative outcome after adult cardiac surgery","volume":"26","author":"Kogan","year":"2012","journal-title":"J Anesth"},{"key":"10.1053\/j.jvca.2021.02.007_bib0041","doi-asserted-by":"crossref","first-page":"2189","DOI":"10.1016\/j.athoracsur.2006.01.025","article-title":"Anaerobic metabolism during cardiopulmonary bypass: Predictive value of carbon dioxide derived parameters","volume":"81","author":"Ranucci","year":"2006","journal-title":"Ann Thorac Surg"},{"key":"10.1053\/j.jvca.2021.02.007_bib0042","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000008029","article-title":"Risk factor analysis for nonocclusive mesenteric ischemia following cardiac surgery - a case control study","volume":"96","author":"Lim","year":"2017","journal-title":"Medicine"},{"key":"10.1053\/j.jvca.2021.02.007_bib0043","first-page":"230","article-title":"How can the prognosis of acute mesenteric artery ischemia be improved? Results of a retrospective analysis","volume":"123","author":"Meyer","year":"1998","journal-title":"Zentralbl Chir"},{"key":"10.1053\/j.jvca.2021.02.007_bib0044","first-page":"381","article-title":"Usefulness of plasma lactate concentration in the diagnosis of acute abdominal disease","volume":"160","author":"Lange","year":"1994","journal-title":"Eur J Surg"},{"key":"10.1053\/j.jvca.2021.02.007_bib0045","first-page":"30","article-title":"Hyperlactatemia after coronary artery bypass surgery: Risk factors and effect on mortality","volume":"19","author":"Y\u0131lmaz","year":"2010","journal-title":"Turkish J Thorac Cardiovasc Surg"},{"key":"10.1053\/j.jvca.2021.02.007_bib0046","doi-asserted-by":"crossref","first-page":"e13551","DOI":"10.1371\/journal.pone.0013551","article-title":"Intensive care unit admission parameters improve the accuracy of operative mortality predictive models in cardiac surgery","volume":"5","author":"Ranucci","year":"2010","journal-title":"PLoS One"},{"key":"10.1053\/j.jvca.2021.02.007_bib0047","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.bja.2018.12.019","article-title":"Vasoactive-inotropic score and the prediction of morbidity and mortality after cardiac surgery","volume":"122","author":"Koponen","year":"2019","journal-title":"Br J Anaesth"},{"key":"10.1053\/j.jvca.2021.02.007_bib0048","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/s00540-018-2447-2","article-title":"Vasoactive-inotropic score as a predictor of morbidity and mortality in adults after cardiac surgery with cardiopulmonary bypass","volume":"32","author":"Yamazaki","year":"2018","journal-title":"J Anesth"}],"container-title":["Journal of Cardiothoracic and Vascular Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053077021001026?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053077021001026?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T07:50:53Z","timestamp":1760946653000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1053077021001026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":48,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["S1053077021001026"],"URL":"https:\/\/doi.org\/10.1053\/j.jvca.2021.02.007","relation":{},"ISSN":["1053-0770"],"issn-type":[{"value":"1053-0770","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Monitoring of the Progression of the Perioperative Serum Lactate Concentration Improves the Accuracy of the Prediction of Acute Mesenteric Ischemia Development After Cardiovascular Surgery","name":"articletitle","label":"Article Title"},{"value":"Journal of Cardiothoracic and Vascular Anesthesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.jvca.2021.02.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}