{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T07:05:20Z","timestamp":1791875120777,"version":"4.3.4"},"reference-count":31,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,8,17]],"date-time":"2021-08-17T00:00:00Z","timestamp":1629158400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jcardioanesthesia.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiothoracic and Vascular Anesthesia"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1053\/j.jvca.2021.08.020","type":"journal-article","created":{"date-parts":[[2021,8,19]],"date-time":"2021-08-19T04:23:18Z","timestamp":1629346998000},"page":"1029-1039","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Rotational Thromboelastometry-Guided Transfusion Protocol to Reduce Allogeneic Blood Transfusion in Proximal Aortic Surgery With Deep Hypothermic Circulatory Arrest"],"prefix":"10.1053","volume":"36","author":[{"given":"Senned","family":"Karrar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ted","family":"Reniers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anika","family":"Filius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeroen J.H.","family":"Bunge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0221-9239","authenticated-orcid":false,"given":"Jos A.","family":"Bekkers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4022-9574","authenticated-orcid":false,"given":"Sanne E.","family":"Hoeks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maarten ter","family":"Horst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/j.jvca.2021.08.020_bib0001","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/S0022-5223(94)70334-5","article-title":"Hypothermic circulatory arrest in operations on the thoracic aorta: Determinants of operative mortality and neurologic outcome","volume":"107","author":"Ergin","year":"1994","journal-title":"J Thoracic Cardiovasc Surg"},{"key":"10.1053\/j.jvca.2021.08.020_bib0002","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.athoracsur.2017.06.072","article-title":"Safety of moderate hypothermia with antegrade cerebral perfusion in total aortic arch replacement","volume":"105","author":"Keeling","year":"2018","journal-title":"Ann Thorac Surg"},{"key":"10.1053\/j.jvca.2021.08.020_bib0003","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.athoracsur.2010.03.118","article-title":"Moderate hypothermia and unilateral selective antegrade cerebral perfusion: A contemporary cerebral protection strategy for aortic arch surgery","volume":"90","author":"Leshnower","year":"2010","journal-title":"Ann Thorac Surg"},{"key":"10.1053\/j.jvca.2021.08.020_bib0004","first-page":"222","article-title":"Individual strategies of hemostasis for thoracic aortic surgery","volume":"12","author":"de Figueiredo","year":"1997","journal-title":"J Card Surg"},{"key":"10.1053\/j.jvca.2021.08.020_bib0005","first-page":"229","article-title":"Hemostasis for aortic surgery","volume":"12","author":"Svensson","year":"1997","journal-title":"J Card Surg"},{"key":"10.1053\/j.jvca.2021.08.020_bib0006","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1111\/trf.15137","article-title":"Improving safety in blood transfusion using failure mode and effect analysis","volume":"59","author":"Mora","year":"2019","journal-title":"Transfusion"},{"key":"10.1053\/j.jvca.2021.08.020_bib0007","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1111\/j.1537-2995.2006.00930.x","article-title":"Transfusion-related acute lung injury and pulmonary edema in critically ill patients: A retrospective study","volume":"46","author":"Rana","year":"2006","journal-title":"Transfusion"},{"key":"10.1053\/j.jvca.2021.08.020_bib0008","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/vox.12466","article-title":"Incidence and clinical characteristics of transfusion-associated circulatory overload using an active surveillance algorithm","volume":"112","author":"Roubinian","year":"2017","journal-title":"Vox Sang"},{"key":"10.1053\/j.jvca.2021.08.020_bib0009","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1111\/j.1537-2995.2010.02622.x","article-title":"Prevalence, incidence, and residual risk of human immunodeficiency virus and hepatitis C virus infections among United States blood donors since the introduction of nucleic acid testing","volume":"50","author":"Zou","year":"2010","journal-title":"Transfusion"},{"key":"10.1053\/j.jvca.2021.08.020_bib0010","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/j.jtcvs.2010.04.043","article-title":"Thromboelastometrically guided transfusion protocol during aortic surgery with circulatory arrest: A prospective, randomized trial","volume":"140","author":"Girdauskas","year":"2010","journal-title":"J Thoracic Cardiovasc Surg"},{"key":"10.1053\/j.jvca.2021.08.020_bib0011","first-page":"959","article-title":"Changing from aprotinin to tranexamic acid results in increased use of blood products and recombinant factor VIIa for aortic surgery requiring hypothermic arrest","volume":"24","author":"Sniecinski","year":"2010","journal-title":"J Thoracic Cardiovasc Surg"},{"key":"10.1053\/j.jvca.2021.08.020_bib0012","first-page":"1214","article-title":"Targeting blood products transfusion in trauma: What is the role of thromboelastography?","volume":"82","author":"Figueiredo","year":"2016","journal-title":"Minerva Anestesiol"},{"key":"10.1053\/j.jvca.2021.08.020_bib0013","first-page":"S64","article-title":"[Coagulation management during liver transplantation] Gerinnungsmanagement bei Lebertransplantationen","volume":"26","author":"Gorlinger","year":"2006","journal-title":"Hamostaseologie"},{"key":"10.1053\/j.jvca.2021.08.020_bib0014","doi-asserted-by":"crossref","first-page":"S20","DOI":"10.1053\/j.jvca.2013.05.014","article-title":"Management of hemorrhage in cardiothoracic surgery","volume":"27","author":"Gorlinger","year":"2013","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10.1053\/j.jvca.2021.08.020_bib0015","doi-asserted-by":"crossref","first-page":"285","DOI":"10.4103\/0974-2700.102357","article-title":"Hemorrhagic shock: The \"physiology approach\"","volume":"5","author":"Bonanno","year":"2012","journal-title":"J Emerg Trauma Shock"},{"key":"10.1053\/j.jvca.2021.08.020_bib0016","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1213\/ane.0b013e31817340ad","article-title":"Hypothermia and acidosis synergistically impair coagulation in human whole blood","volume":"106","author":"Dirkmann","year":"2008","journal-title":"Anesth Analg"},{"key":"10.1053\/j.jvca.2021.08.020_bib0017","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.tmrv.2013.08.004","article-title":"Roles of Thrombelastography and thromboelastometry for patient blood management in cardiac surgery","volume":"27","author":"Bolliger","year":"2013","journal-title":"Transfus Med Rev"},{"key":"10.1053\/j.jvca.2021.08.020_bib0018","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.jss.2016.03.008","article-title":"Point-of-care thromboelastography\/thromboelastometry-based coagulation management in cardiac surgery: A meta-analysis of 8332 patients","volume":"203","author":"Deppe","year":"2016","journal-title":"J Surg Res"},{"key":"10.1053\/j.jvca.2021.08.020_bib0019","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.21037\/jtd.2019.04.39","article-title":"Thromboelastography or rotational thromboelastometry for bleeding management in adults undergoing cardiac surgery: A systematic review with meta-analysis and trial sequential analysis","volume":"11","author":"Li","year":"2019","journal-title":"J Thorac Dis"},{"key":"10.1053\/j.jvca.2021.08.020_bib0020","article-title":"Thromboelastography (TEG) or thromboelastometry (ROTEM) to monitor haemostatic treatment versus usual care in adults or children with bleeding","volume":"2016","author":"Wikkels\u00f8","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1053\/j.jvca.2021.08.020_bib0021","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1053\/j.jvca.2013.02.009","article-title":"Transfusion of allogeneic blood products in proximal aortic surgery with hypothermic circulatory arrest: Effect of thromboelastometry-guided transfusion management","volume":"27","author":"Fassl","year":"2013","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10.1053\/j.jvca.2021.08.020_bib0022","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.jtcvs.2018.07.043","article-title":"Evaluation of the real-world impact of rotational thromboelastometry-guided transfusion protocol in patients undergoing proximal aortic surgery","volume":"157","author":"St-Onge","year":"2019","journal-title":"J Thoracic Cardiovasc Surg"},{"key":"10.1053\/j.jvca.2021.08.020_bib0023","unstructured":"Anesthesiologists ASo. Standards for basic anaesthetic monitoring. Available at: https:\/\/www.asahq.org\/standards-and-guidelines\/standards-for-basic-anesthetic-monitoring. Accessed 28 november 2019."},{"key":"10.1053\/j.jvca.2021.08.020_bib0024","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1097\/ALN.0b013e318264c644","article-title":"Point-of-care testing: A prospective, randomized clinical trial of efficacy in coagulopathic cardiac surgery patients","volume":"117","author":"Weber","year":"2012","journal-title":"Anesthesiology"},{"key":"10.1053\/j.jvca.2021.08.020_bib0025","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1097\/01.TA.0000156246.53383.9F","article-title":"Independent contributions of hypothermia and acidosis to coagulopathy in swine","volume":"58","author":"Martini","year":"2005","journal-title":"J Trauma"},{"key":"10.1053\/j.jvca.2021.08.020_bib0026","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1177\/1076029618790092","article-title":"Role of thromboelastography and rotational thromboelastometry in the management of cardiovascular diseases","volume":"24","author":"Korpallov\u00e1","year":"2018","journal-title":"Clin Appl Thromb Hemost"},{"key":"10.1053\/j.jvca.2021.08.020_bib0027","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1053\/j.jvca.2020.07.050","article-title":"Point-of-care platelet function monitoring: Implications for patients with platelet inhibitors in cardiac surgery","volume":"35","author":"Bolliger","year":"2021","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10.1053\/j.jvca.2021.08.020_bib0028","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1161\/CIRCULATIONAHA.117.031264","article-title":"Insights from the international registry of acute aortic dissection","volume":"137","author":"Arturo","year":"2018","journal-title":"Circulation"},{"key":"10.1053\/j.jvca.2021.08.020_bib0029","first-page":"077","article-title":"German registry for acute aortic dissection type A: Structure, results, and future perspectives","volume":"65","author":"Boening","year":"2017","journal-title":"Thorac Cardiovasc Surg"},{"key":"10.1053\/j.jvca.2021.08.020_bib0030","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1093\/ejcts\/ezx231","article-title":"Hospital volumes and later year of operation correlates with better outcomes in acute Type A aortic dissection","volume":"53","author":"Geirsson","year":"2017","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1053\/j.jvca.2021.08.020_bib0031","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/0002-9343(75)90351-4","article-title":"Coagulopathy in ruptured or dissecting aortic aneurysms","volume":"59","author":"ten Cate","year":"1975","journal-title":"Am J Med"}],"container-title":["Journal of Cardiothoracic and Vascular Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053077021006923?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053077021006923?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T07:59:34Z","timestamp":1760947174000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1053077021006923"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["S1053077021006923"],"URL":"https:\/\/doi.org\/10.1053\/j.jvca.2021.08.020","relation":{},"ISSN":["1053-0770"],"issn-type":[{"value":"1053-0770","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rotational Thromboelastometry-Guided Transfusion Protocol to Reduce Allogeneic Blood Transfusion in Proximal Aortic Surgery With Deep Hypothermic Circulatory Arrest","name":"articletitle","label":"Article Title"},{"value":"Journal of Cardiothoracic and Vascular Anesthesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.jvca.2021.08.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}