{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T15:04:32Z","timestamp":1785683072931,"version":"3.56.0"},"reference-count":94,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","semdiagpath.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Diagnostic Pathology"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1053\/j.semdp.2016.11.004","type":"journal-article","created":{"date-parts":[[2016,12,24]],"date-time":"2016-12-24T13:06:45Z","timestamp":1482584805000},"page":"44-59","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Aggressive cutaneous T-cell lymphomas"],"prefix":"10.1053","volume":"34","author":[{"given":"Jacqueline M.","family":"Junkins-Hopkins, MD","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1053\/j.semdp.2016.11.004_bib1","doi-asserted-by":"crossref","first-page":"3768","DOI":"10.1182\/blood-2004-09-3502","article-title":"WHO-EORTC classification for cutaneous lymphomas","volume":"105","author":"Willemze","year":"2005","journal-title":"Blood"},{"key":"10.1053\/j.semdp.2016.11.004_bib2","series-title":"WHO Classification of Tumors of Haematopoietic and Lymphoid Tissue","author":"Swerdlow","year":"2008"},{"issue":"8","key":"10.1053\/j.semdp.2016.11.004_bib3","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1097\/PAS.0b013e3181e75356","article-title":"A variant of lymphomatoid papulosis simulating primary cutaneous aggressive epidermotropic CD8+ cytotoxic T-cell lymphoma","volume":"34","author":"Saggini","year":"2010","journal-title":"Am J Surg Pathol"},{"issue":"1","key":"10.1053\/j.semdp.2016.11.004_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/PAS.0b013e3182648596","article-title":"Angioinvasive lymphomatoid papulosis: a new variant simulating aggressive lymphomas","volume":"37","author":"Kempf","year":"2013","journal-title":"Am J Surg Pathol"},{"issue":"6","key":"10.1053\/j.semdp.2016.11.004_bib5","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1182\/blood-2007-03-055749","volume":"110","author":"Olsen","year":"2007","journal-title":"Blood"},{"issue":"6","key":"10.1053\/j.semdp.2016.11.004_bib6","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1111\/bjd.12909","article-title":"Prognostic factors, prognostic indices and staging in mycosis fungoides and Sezary syndrome: where are we now?","volume":"170","author":"Scarisbrick","year":"2014","journal-title":"Br J Dermatol"},{"issue":"20","key":"10.1053\/j.semdp.2016.11.004_bib7","doi-asserted-by":"crossref","first-page":"3364","DOI":"10.1200\/JCO.2008.16.1307","article-title":"Primary cutaneous small\/medium CD4+ T-cell lymphomas: a heterogeneous group of tumors with different clinicopathologic features and outcome","volume":"26","author":"Garcia-Herrera","year":"2008","journal-title":"J Clin Oncol"},{"issue":"2","key":"10.1053\/j.semdp.2016.11.004_bib8","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1182\/blood-2006-10-054601","volume":"110","author":"Kim","year":"2007","journal-title":"Blood"},{"issue":"7","key":"10.1053\/j.semdp.2016.11.004_bib9","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1182\/blood-2011-08-376319","article-title":"Prognostic factors in transformed mycosis fungoides: a retrospective analysis of 100 cases","volume":"119","author":"Benner","year":"2012","journal-title":"Blood"},{"issue":"2","key":"10.1053\/j.semdp.2016.11.004_bib10","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1182\/blood-2007-04-087288","article-title":"Subcutaneous panniculitis-like T-cell lymphoma: definition, classification, and prognostic factors: an EORTC cutaneous lymphoma Group Study of 83 cases","volume":"111","author":"Willemze","year":"2008","journal-title":"Blood"},{"issue":"6","key":"10.1053\/j.semdp.2016.11.004_bib11","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1016\/j.jaad.2012.04.043","article-title":"Sezary syndrome: a study of 176 patients at mayo clinic","volume":"67","author":"Kubica","year":"2012","journal-title":"J Am Acad Dermatol"},{"issue":"31","key":"10.1053\/j.semdp.2016.11.004_bib12","doi-asserted-by":"crossref","first-page":"4730","DOI":"10.1200\/JCO.2009.27.7665","article-title":"Survival outcomes and prognostic factors in mycosis fungoides\/Sezary syndrome: validation of the revised international society for cutaneous lymphomas\/European organisation for research and treatment of cancer staging proposal","volume":"28","author":"Agar","year":"2010","journal-title":"J Clin Oncol"},{"issue":"2","key":"10.1053\/j.semdp.2016.11.004_bib13","first-page":"265","article-title":"Transformation of cutaneous T cell lymphoma to large cell lymphoma. A clinicopathologic and immunologic study","volume":"132","author":"Salhany","year":"1988","journal-title":"Am J Pathol"},{"issue":"2","key":"10.1053\/j.semdp.2016.11.004_bib14","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1200\/JCO.1987.5.2.208","article-title":"Cytologic transformation in cutaneous T cell lymphoma: a clinicopathologic entity associated with poor prognosis","volume":"5","author":"Dmitrovsky","year":"1987","journal-title":"J Clin Oncol"},{"issue":"4","key":"10.1053\/j.semdp.2016.11.004_bib15","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1002\/hon.2900080406","article-title":"Clinical features associated with transformation of cerebriform T-cell lymphoma to a large cell process","volume":"8","author":"Greer","year":"1990","journal-title":"Hematol Oncol"},{"issue":"4","key":"10.1053\/j.semdp.2016.11.004_bib16","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1182\/blood.V92.4.1150","article-title":"Transformation of mycosis fungoides\/Sezary syndrome: clinical characteristics and prognosis","volume":"92","author":"Diamandidou","year":"1998","journal-title":"Blood"},{"issue":"7","key":"10.1053\/j.semdp.2016.11.004_bib17","first-page":"2212","article-title":"Transformation of mycosis fungoides: clinicopathological and prognostic features of 45 cases. French study group of cutaneious lymphomas","volume":"95","author":"Vergier","year":"2000","journal-title":"Blood"},{"issue":"2","key":"10.1053\/j.semdp.2016.11.004_bib18","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1111\/j.1365-2133.2007.08008.x","article-title":"Transformed mycosis fungoides: clinicopathological features and outcome","volume":"157","author":"Barberio","year":"2007","journal-title":"Br J Dermatol"},{"issue":"8","key":"10.1053\/j.semdp.2016.11.004_bib19","doi-asserted-by":"crossref","first-page":"3082","DOI":"10.1182\/blood-2008-05-154609","article-title":"Long-term outcomes of patients with advanced-stage cutaneous T-cell lymphoma and large cell transformation","volume":"112","author":"Arulogun","year":"2008","journal-title":"Blood"},{"issue":"1","key":"10.1053\/j.semdp.2016.11.004_bib20","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.clml.2015.11.010","article-title":"Retrospective analysis of prognostic factors in 187 cases of transformed mycosis fungoides","volume":"16","author":"Talpur","year":"2016","journal-title":"Clin Lymphoma Myeloma Leuk"},{"issue":"4","key":"10.1053\/j.semdp.2016.11.004_bib21","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1001\/archderm.136.4.504","article-title":"Mycosis fungoides: disease evolution and prognosis of 309 Dutch patients","volume":"136","author":"van Doorn","year":"2000","journal-title":"Arch Dermatol"},{"issue":"9","key":"10.1053\/j.semdp.2016.11.004_bib22","doi-asserted-by":"crossref","first-page":"e327","DOI":"10.1111\/ijd.12875","article-title":"Correlations between clinical and pathological features in 17 cases of mycosis fungoides before and after transformation","volume":"54","author":"Bittencourt","year":"2015","journal-title":"Int J Dermatol"},{"issue":"12","key":"10.1053\/j.semdp.2016.11.004_bib23","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1097\/PAS.0000000000000091","article-title":"CD20 antigen may be expressed by reactive or lymphomatous cells of transformed mycosis fungoides: diagnostic and prognostic impact","volume":"37","author":"Jullie","year":"2013","journal-title":"Am J Surg Pathol"},{"issue":"32","key":"10.1053\/j.semdp.2016.11.004_bib24","doi-asserted-by":"crossref","first-page":"3766","DOI":"10.1200\/JCO.2015.61.7142","article-title":"Cutaneous lymphoma international consortium study of outcome in advanced stages of mycosis fungoides and sezary syndrome: effect of specific prognostic markers on survival and development of a prognostic model","volume":"33","author":"Scarisbrick","year":"2015","journal-title":"J Clin Oncol"},{"issue":"12","key":"10.1053\/j.semdp.2016.11.004_bib25","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1097\/PAS.0b013e3181bf677d","article-title":"CD30 expression and proliferative fraction in nontransformed mycosis fungoides","volume":"33","author":"Edinger","year":"2009","journal-title":"Am J Surg Pathol"},{"issue":"7","key":"10.1053\/j.semdp.2016.11.004_bib26","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1097\/PAT.0000000000000166","article-title":"Mycosis fungoides with large cell transformation: clinicopathological features and prognostic factors","volume":"46","author":"Pulitzer","year":"2014","journal-title":"Pathology"},{"issue":"3","key":"10.1053\/j.semdp.2016.11.004_bib27","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1111\/bjd.13476","article-title":"Diagnostic and prognostic significance of CDKN2A\/CDKN2B deletions in patients with transformed mycosis fungoides and primary cutaneous CD30-positive lymphoproliferative disease","volume":"172","author":"Nicolae-Cristea","year":"2015","journal-title":"Br J Dermatol"},{"issue":"4","key":"10.1053\/j.semdp.2016.11.004_bib28","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1016\/S0002-9440(10)65372-2","article-title":"Expression of cytotoxic proteins by neoplastic T cells in mycosis fungoides increases with progression from plaque stage to tumor stage disease","volume":"154","author":"Vermeer","year":"1999","journal-title":"Am J Pathol"},{"issue":"Suppl:S181-S90","key":"10.1053\/j.semdp.2016.11.004_bib29","first-page":"e4","article-title":"Increased levels of plasma epstein barr virus DNA identify a poor-risk subset of patients with advanced stage cutaneous T-cell lymphoma","volume":"16","author":"Haverkos","year":"2016","journal-title":"Clin Lymphoma Myeloma Leuk"},{"issue":"2","key":"10.1053\/j.semdp.2016.11.004_bib30","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.jaad.2013.09.007","article-title":"Large-cell transformation of mycosis fungoides-differential diagnosis with implications for clinical management: a consensus statement of the US cutaneous lymphoma consortium","volume":"70","author":"Kadin","year":"2014","journal-title":"J Am Acad Dermatol"},{"issue":"6","key":"10.1053\/j.semdp.2016.11.004_bib31","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1111\/bjd.13690","article-title":"Assessment of diagnostic criteria between primary cutaneous anaplastic large-cell lymphoma and CD30-rich transformed mycosis fungoides; a study of 66 cases","volume":"172","author":"Fauconneau","year":"2015","journal-title":"Br J Dermatol"},{"issue":"4","key":"10.1053\/j.semdp.2016.11.004_bib32","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.leukres.2012.12.001","article-title":"The significance of MUM1\/IRF4 protein expression and IRF4 translocation of CD30(+) cutaneous T-cell lymphoproliferative disorders: a study of 53 cases","volume":"37","author":"Kiran","year":"2013","journal-title":"Leuk Res"},{"issue":"4","key":"10.1053\/j.semdp.2016.11.004_bib33","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1038\/modpathol.2010.225","article-title":"Specificity of IRF4 translocations for primary cutaneous anaplastic large cell lymphoma: a multicenter study of 204 skin biopsies","volume":"24","author":"Wada","year":"2011","journal-title":"Mod Pathol"},{"key":"10.1053\/j.semdp.2016.11.004_bib34","first-page":"1","article-title":"Genetics of anaplastic large cell lymphoma","author":"Zeng","year":"2015","journal-title":"Leuk Lymphoma"},{"issue":"9","key":"10.1053\/j.semdp.2016.11.004_bib35","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1001\/jamadermatol.2016.1597","article-title":"Clinical staging and prognostic factors in folliculotropic mycosis fungoides","volume":"152","author":"van Santen","year":"2016","journal-title":"JAMA Dermatol"},{"issue":"2","key":"10.1053\/j.semdp.2016.11.004_bib36","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1001\/archderm.138.2.191","article-title":"Follicular mycosis fungoides, a distinct disease entity with or without associated follicular mucinosis: a clinicopathologic and follow-up study of 51 patients","volume":"138","author":"van Doorn","year":"2002","journal-title":"Arch Dermatol"},{"issue":"2","key":"10.1053\/j.semdp.2016.11.004_bib37","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.jaad.2016.03.009","article-title":"New insights into folliculotropic mycosis fungoides (FMF): a single-center experience","volume":"75","author":"Hodak","year":"2016","journal-title":"J Am Acad Dermatol"},{"issue":"6","key":"10.1053\/j.semdp.2016.11.004_bib38","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1001\/archderm.144.6.738","article-title":"Folliculotropic mycosis fungoides: an aggressive variant of cutaneous T-cell lymphoma","volume":"144","author":"Gerami","year":"2008","journal-title":"Arch Dermatol"},{"issue":"3","key":"10.1053\/j.semdp.2016.11.004_bib39","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1128\/CMR.00063-09","article-title":"Epidemiology, treatment, and prevention of human T-cell leukemia virus type 1-associated diseases","volume":"23","author":"Goncalves","year":"2010","journal-title":"Clin Microbiol Rev"},{"issue":"12","key":"10.1053\/j.semdp.2016.11.004_bib40","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1136\/jcp.2007.052456","article-title":"Adult T-cell leukaemia\/lymphoma","volume":"60","author":"Matutes","year":"2007","journal-title":"J Clin Pathol"},{"issue":"1","key":"10.1053\/j.semdp.2016.11.004_bib41","doi-asserted-by":"crossref","first-page":"103","DOI":"10.4103\/0019-5154.147846","article-title":"Multifaceted adult T-cell leukemia\/lymphoma in India: a case series","volume":"60","author":"Khader","year":"2015","journal-title":"Indian J Dermatol"},{"issue":"39","key":"10.1053\/j.semdp.2016.11.004_bib42","doi-asserted-by":"crossref","first-page":"6047","DOI":"10.1038\/sj.onc.1208979","article-title":"Natural history of adult T-cell leukemia\/lymphoma and approaches to therapy","volume":"24","author":"Taylor","year":"2005","journal-title":"Oncogene"},{"issue":"4","key":"10.1053\/j.semdp.2016.11.004_bib43","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1080\/02841860802657235","article-title":"Adult T-cell leukemia\/lymphoma (ATL) presenting in the skin: clinical, histological and immunohistochemical features of 52 cases","volume":"48","author":"Bittencourt","year":"2009","journal-title":"Acta Oncol"},{"issue":"3","key":"10.1053\/j.semdp.2016.11.004_bib44","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1067\/mjd.2001.111349","article-title":"HTLV-I-associated granulomatous T-cell lymphoma in a child","volume":"44","author":"Lewis","year":"2001","journal-title":"J Am Acad Dermatol"},{"issue":"3","key":"10.1053\/j.semdp.2016.11.004_bib45","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1111\/j.1365-2141.1991.tb08051.x","article-title":"Diagnostic criteria and classification of clinical subtypes of adult T-cell leukaemia-lymphoma. A report from the lymphoma study group (1984-87)","volume":"79","author":"Shimoyama","year":"1991","journal-title":"Br J Haematol"},{"issue":"12","key":"10.1053\/j.semdp.2016.11.004_bib46","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1111\/j.1346-8138.1999.tb02093.x","article-title":"Clinicopathologic analysis of 124 cases of adult T-cell leukemia\/lymphoma with cutaneous manifestations: the smouldering type with skin manifestations has a poorer prognosis than previously thought","volume":"26","author":"Setoyama","year":"1999","journal-title":"J Dermatol"},{"issue":"2","key":"10.1053\/j.semdp.2016.11.004_bib47","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.jaad.2014.10.006","article-title":"Cutaneous manifestations of human T-cell lymphotrophic virus type-1-associated adult T-cell leukemia\/lymphoma: a single-center, retrospective study","volume":"72","author":"Marchetti","year":"2015","journal-title":"J Am Acad Dermatol"},{"issue":"4","key":"10.1053\/j.semdp.2016.11.004_bib48","doi-asserted-by":"crossref","first-page":"e1003263","DOI":"10.1371\/journal.ppat.1003263","article-title":"Strongyloidiasis and infective dermatitis alter human T lymphotropic virus-1 clonality in vivo","volume":"9","author":"Gillet","year":"2013","journal-title":"PLoS Pathog"},{"issue":"8782\u20138783","key":"10.1053\/j.semdp.2016.11.004_bib49","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1016\/0140-6736(91)92413-V","article-title":"Childhood infective dermatitis evolving into adult T-cell leukaemia after 17 years","volume":"338","author":"Hanchard","year":"1991","journal-title":"Lancet"},{"issue":"8727","key":"10.1053\/j.semdp.2016.11.004_bib50","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1016\/0140-6736(90)92896-P","article-title":"Infective dermatitis of Jamaican children: a marker for HTLV-I infection","volume":"336","author":"LaGrenade","year":"1990","journal-title":"Lancet"},{"issue":"3","key":"10.1053\/j.semdp.2016.11.004_bib51","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1200\/JCO.2008.18.2428","article-title":"Definition, prognostic factors, treatment, and response criteria of adult T-cell leukemia-lymphoma: a proposal from an international consensus meeting","volume":"27","author":"Tsukasaki","year":"2009","journal-title":"J Clin Oncol"},{"issue":"1","key":"10.1053\/j.semdp.2016.11.004_bib52","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0190-9622(97)70351-7","article-title":"Clinical and histologic spectrum of human T-cell lymphotropic virus type I-associated lymphoma involving the skin","volume":"36","author":"Kikuchi","year":"1997","journal-title":"J Am Acad Dermatol"},{"issue":"22","key":"10.1053\/j.semdp.2016.11.004_bib53","doi-asserted-by":"crossref","first-page":"4337","DOI":"10.1182\/blood-2009-09-242347","article-title":"Long-term study of indolent adult T-cell leukemia-lymphoma","volume":"115","author":"Takasaki","year":"2010","journal-title":"Blood"},{"issue":"15","key":"10.1053\/j.semdp.2016.11.004_bib54","doi-asserted-by":"crossref","first-page":"3961","DOI":"10.1182\/blood-2010-11-316794","article-title":"Type of skin eruption is an independent prognostic indicator for adult T-cell leukemia\/lymphoma","volume":"117","author":"Sawada","year":"2011","journal-title":"Blood"},{"issue":"1","key":"10.1053\/j.semdp.2016.11.004_bib55","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/PAS.0000000000000312","article-title":"Primary cutaneous NK\/T-cell lymphoma, nasal type and CD56-positive peripheral T-cell lymphoma: a cellular lineage and clinicopathologic study of 60 patients from Asia","volume":"39","author":"Takata","year":"2015","journal-title":"Am J Surg Pathol"},{"issue":"2","key":"10.1053\/j.semdp.2016.11.004_bib56","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/j.1365-2133.2008.08922.x","article-title":"Extranodal NK\/T-cell lymphoma with cutaneous involvement: 'nasal' vs 'nasal-type' subgroups--a retrospective study of 18 patients","volume":"160","author":"Choi","year":"2009","journal-title":"Br J Dermatol"},{"issue":"6","key":"10.1053\/j.semdp.2016.11.004_bib57","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1097\/01.pas.0000126719.71954.4f","article-title":"Subcutaneous, blastic natural killer (NK), NK\/T-cell, and other cytotoxic lymphomas of the skin: a morphologic, immunophenotypic, and molecular study of 50 patients","volume":"28","author":"Massone","year":"2004","journal-title":"Am J Surg Pathol"},{"issue":"4","key":"10.1053\/j.semdp.2016.11.004_bib58","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1097\/PAS.0b013e31824433d8","article-title":"Extranodal NK\/T-cell lymphoma, nasal type, includes cases of natural killer cell and alphabeta, gammadelta, and alphabeta\/gammadelta T-cell origin: a comprehensive clinicopathologic and phenotypic study","volume":"36","author":"Pongpruttipan","year":"2012","journal-title":"Am J Surg Pathol"},{"issue":"8","key":"10.1053\/j.semdp.2016.11.004_bib59","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1097\/PAS.0b013e31821ec4b5","article-title":"Clinicopathologic and molecular features of 122 Brazilian cases of nodal and extranodal NK\/T-cell lymphoma, nasal type, with EBV subtyping analysis","volume":"35","author":"Gualco","year":"2011","journal-title":"Am J Surg Pathol"},{"issue":"4","key":"10.1053\/j.semdp.2016.11.004_bib60","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/j.jaad.2013.11.028","article-title":"Clinicopathologic and molecular features in cutaneous extranodal natural killer-\/T-cell lymphoma, nasal type, with aggressive and indolent course","volume":"70","author":"Fried","year":"2014","journal-title":"J Am Acad Dermatol"},{"issue":"2","key":"10.1053\/j.semdp.2016.11.004_bib61","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/S0002-9440(10)65144-9","article-title":"Primary cutaneous CD8-positive epidermotropic cytotoxic T cell lymphomas. A distinct clinicopathological entity with an aggressive clinical behavior","volume":"155","author":"Berti","year":"1999","journal-title":"Am J Pathol"},{"issue":"4","key":"10.1053\/j.semdp.2016.11.004_bib62","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1016\/j.jaad.2011.07.043","article-title":"Primary cutaneous aggressive epidermotropic CD8+ T-cell lymphoma: proposed diagnostic criteria and therapeutic evaluation","volume":"67","author":"Nofal","year":"2012","journal-title":"J Am Acad Dermatol"},{"issue":"4","key":"10.1053\/j.semdp.2016.11.004_bib63","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1111\/his.12371","article-title":"Aggressive epidermotropic cutaneous CD8+ lymphoma: a cutaneous lymphoma with distinct clinical and pathological features. Report of an EORTC cutaneous lymphoma task force workshop","volume":"67","author":"Robson","year":"2015","journal-title":"Histopathology"},{"issue":"2","key":"10.1053\/j.semdp.2016.11.004_bib64","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1007\/s12185-015-1895-9","article-title":"Molecular genetic and cytogenetic analysis of a primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma","volume":"103","author":"Kato","year":"2016","journal-title":"Int J Hematol"},{"issue":"2","key":"10.1053\/j.semdp.2016.11.004_bib65","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/S0190-9622(03)00065-3","article-title":"Progressive epidermotropic CD8+\/CD4- primary cutaneous CD30+ lymphoproliferative disorder in a patient with sarcoidosis","volume":"51","author":"Gelfand","year":"2004","journal-title":"J Am Acad Dermatol"},{"issue":"8","key":"10.1053\/j.semdp.2016.11.004_bib66","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1097\/PAS.0b013e318282d01e","article-title":"Chromosomal rearrangements of 6p25.3 define a new subtype of lymphomatoid papulosis","volume":"37","author":"Karai","year":"2013","journal-title":"Am J Surg Pathol"},{"issue":"1","key":"10.1053\/j.semdp.2016.11.004_bib67","doi-asserted-by":"crossref","first-page":"136","DOI":"10.2340\/00015555-2155","article-title":"A case of primary cutaneous aggressive epidermotropic CD8+ cytotoxic T-cell lymphoma misdiagnosed as febrile ulceronecrotic Mucha-Habermann disease","volume":"96","author":"Sheng","year":"2016","journal-title":"Acta Derm Venereol"},{"issue":"6","key":"10.1053\/j.semdp.2016.11.004_bib68","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1016\/j.jaad.2004.06.009","article-title":"Febrile ulceronecrotic Mucha-Habermann disease with clonality: a cutaneous T-cell lymphoma entity?","volume":"51","author":"Cozzio","year":"2004","journal-title":"J Am Acad Dermatol"},{"issue":"12","key":"10.1053\/j.semdp.2016.11.004_bib69","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1097\/PAS.0b013e318068b527","article-title":"Indolent CD8-positive lymphoid proliferation of the ear: a distinct primary cutaneous T-cell lymphoma?","volume":"31","author":"Petrella","year":"2007","journal-title":"Am J Surg Pathol"},{"issue":"2","key":"10.1053\/j.semdp.2016.11.004_bib70","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1111\/cup.12045","article-title":"Indolent CD8(+) lymphoid proliferation of acral sites: a clinicopathologic study of six patients with some atypical features","volume":"40","author":"Greenblatt","year":"2013","journal-title":"J Cutan Pathol"},{"issue":"3","key":"10.1053\/j.semdp.2016.11.004_bib71","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1002\/cncr.11107","article-title":"Cytotoxic\/natural killer cell cutaneous lymphomas. Report of EORTC cutaneous lymphoma task force workshop","volume":"97","author":"Santucci","year":"2003","journal-title":"Cancer"},{"key":"10.1053\/j.semdp.2016.11.004_bib72","doi-asserted-by":"crossref","unstructured":"Guitart J, Martinez-Escala ME, Subtil A, Duvic M, Pulitzer MP, Olsen EA, et al. Primary cutaneous aggressive epidermotropic cytotoxic T-cell lymphomas: reappraisal of a provisional entity in the 2016 WHO classification of cutaneous lymphomas. Mod Pathol. 10.1038\/modpathol.2016.240 [Epub ahead of print].","DOI":"10.1038\/modpathol.2016.240"},{"key":"10.1053\/j.semdp.2016.11.004_bib73","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1182\/asheducation-2009.1.523","article-title":"The 2008 WHO classification of lymphomas: implications for clinical practice and translational research","author":"Jaffe","year":"2009","journal-title":"Hematol Am Soc Hematol Educ Program"},{"issue":"9","key":"10.1053\/j.semdp.2016.11.004_bib74","doi-asserted-by":"crossref","first-page":"3407","DOI":"10.1182\/blood-2002-05-1597","article-title":"Gamma-delta T-cell phenotype is associated with significantly decreased survival in cutaneous T-cell lymphoma","volume":"101","author":"Toro","year":"2003","journal-title":"Blood"},{"issue":"6","key":"10.1053\/j.semdp.2016.11.004_bib75","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1309\/LRKX8CE7GVPCR1FT","article-title":"Hepatosplenic and other gammadelta T-cell lymphomas","volume":"127","author":"Vega","year":"2007","journal-title":"Am J Clin Pathol"},{"issue":"8","key":"10.1053\/j.semdp.2016.11.004_bib76","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1097\/PAS.0b013e31822067d1","article-title":"Nonhepatosplenic gammadelta T-cell lymphomas represent a spectrum of aggressive cytotoxic T-cell lymphomas with a mainly extranodal presentation","volume":"35","author":"Garcia-Herrera","year":"2011","journal-title":"Am J Surg Pathol"},{"issue":"2","key":"10.1053\/j.semdp.2016.11.004_bib77","first-page":"264","article-title":"Gammadelta and alphabeta T-cell acute lymphoblastic leukemia: comparison of their clinical and immunophenotypic features","volume":"90","author":"Matos","year":"2005","journal-title":"Haematologica"},{"issue":"8","key":"10.1053\/j.semdp.2016.11.004_bib78","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1001\/archderm.136.8.1024","article-title":"Gamma delta T-cell lymphoma of the skin: a clinical, microscopic, and molecular study","volume":"136","author":"Toro","year":"2000","journal-title":"Arch Dermatol"},{"issue":"11","key":"10.1053\/j.semdp.2016.11.004_bib79","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1097\/PAS.0b013e31826a5038","article-title":"Cutaneous gammadelta T-cell lymphomas: a spectrum of presentations with overlap with other cytotoxic lymphomas","volume":"36","author":"Guitart","year":"2012","journal-title":"Am J Surg Pathol"},{"issue":"3","key":"10.1053\/j.semdp.2016.11.004_bib80","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1097\/PAS.0b013e318275d1a2","article-title":"TCR-gamma expression in primary cutaneous T-cell lymphomas","volume":"37","author":"Rodriguez-Pinilla","year":"2013","journal-title":"Am J Surg Pathol"},{"issue":"4","key":"10.1053\/j.semdp.2016.11.004_bib81","first-page":"483","article-title":"A rare pediatric case of cutaneous gamma\/delta T-cell lymphoma","volume":"72","author":"Kerbout","year":"2014","journal-title":"Ann Biol Clin"},{"issue":"2","key":"10.1053\/j.semdp.2016.11.004_bib82","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1002\/pbc.23103","article-title":"Cutaneous hematologic disorders in children","volume":"58","author":"Boccara","year":"2012","journal-title":"Pediatr Blood Cancer"},{"issue":"7","key":"10.1053\/j.semdp.2016.11.004_bib83","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1097\/DAD.0000000000000493","article-title":"Phenotypic variation in different lesions of mycosis fungoides biopsied within a short period of time from the same patient","volume":"38","author":"Kash","year":"2016","journal-title":"Am J Dermatopathol"},{"issue":"4","key":"10.1053\/j.semdp.2016.11.004_bib84","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1159\/000327932","article-title":"Two atypical cases of cutaneous gamma\/delta T-cell lymphomas","volume":"222","author":"Caudron","year":"2011","journal-title":"Dermatology"},{"issue":"10","key":"10.1053\/j.semdp.2016.11.004_bib85","doi-asserted-by":"crossref","first-page":"e147","DOI":"10.1097\/DAD.0000000000000608","article-title":"Primary cutaneous gamma-delta (gamma\/delta) T-cell lymphoma: an unusual case with very subtle histopathological findings","volume":"38","author":"Ramani","year":"2016","journal-title":"Am J Dermatopathol"},{"issue":"2","key":"10.1053\/j.semdp.2016.11.004_bib86","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1097\/DAD.0b013e3182624e98","article-title":"Primary cutaneous gamma delta T-cell lymphoma with brain involvement and hemophagocytic syndrome","volume":"35","author":"Chakrapani","year":"2013","journal-title":"Am J Dermatopathol"},{"issue":"6","key":"10.1053\/j.semdp.2016.11.004_bib87","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1309\/AJCPMG37MXKYPUBE","article-title":"Percentage of {gamma}{delta} T cells in panniculitis by paraffin immunohistochemical analysis","volume":"131","author":"Roullet","year":"2009","journal-title":"Am J Clin Pathol"},{"issue":"1","key":"10.1053\/j.semdp.2016.11.004_bib88","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1309\/AJCP8BPFJ5JHUXLU","article-title":"Primary cutaneous gammadelta T-cell lymphoma should be limited to cases with TCRgammadelta expression","volume":"140","author":"Chuang","year":"2013","journal-title":"Am J Clin Pathol"},{"key":"10.1053\/j.semdp.2016.11.004_bib89","doi-asserted-by":"crossref","DOI":"10.1111\/cup.12601","article-title":"Atypical cutaneous gammadelta T cell proliferation with morphologic features of lymphoma but with clinical features and course of PLEVA or lymphomatoid papulosis","author":"King","year":"2015","journal-title":"J Cutan Pathol"},{"key":"10.1053\/j.semdp.2016.11.004_bib90","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.ijid.2014.10.026","article-title":"Stenotrophomonas maltophilia with histopathological features mimicking cutaneous gamma\/delta T-cell lymphoma","volume":"30","author":"Kash","year":"2015","journal-title":"Int J Infect Dis"},{"issue":"10","key":"10.1053\/j.semdp.2016.11.004_bib91","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1097\/DAD.0b013e318289c9b8","article-title":"Rapid progression of primary cutaneous gamma-delta T-cell lymphoma with an initial indolent clinical presentation","volume":"36","author":"Alexander","year":"2014","journal-title":"Am J Dermatopathol"},{"issue":"11","key":"10.1053\/j.semdp.2016.11.004_bib92","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1111\/j.1600-0560.2007.00931.x","article-title":"Transformation of cutaneous gamma\/delta T-cell lymphoma following 15 years of indolent behavior","volume":"35","author":"Hosler","year":"2008","journal-title":"J Cutan Pathol"},{"issue":"6","key":"10.1053\/j.semdp.2016.11.004_bib93","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1182\/blood-2002-07-1960","article-title":"Peripheral T-cell lymphomas unspecified presenting in the skin: analysis of prognostic factors in a group of 82 patients","volume":"102","author":"Bekkenk","year":"2003","journal-title":"Blood"},{"key":"10.1053\/j.semdp.2016.11.004_bib94","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaad.2016.06.011","article-title":"Cutaneous peripheral T-cell lymphoma, not otherwise specified: a single-center prognostic analysis","author":"Tolkachjov","year":"2016","journal-title":"J Am Acad Dermatol"}],"container-title":["Seminars in Diagnostic Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0740257016300946?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0740257016300946?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T06:11:03Z","timestamp":1601273463000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0740257016300946"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":94,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["S0740257016300946"],"URL":"https:\/\/doi.org\/10.1053\/j.semdp.2016.11.004","relation":{},"ISSN":["0740-2570"],"issn-type":[{"value":"0740-2570","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aggressive cutaneous T-cell lymphomas","name":"articletitle","label":"Article Title"},{"value":"Seminars in Diagnostic Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.semdp.2016.11.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}