{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T06:01:52Z","timestamp":1778824912109,"version":"3.51.4"},"reference-count":90,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Seminars in Nuclear Medicine"],"published-print":{"date-parts":[[2009,5]]},"DOI":"10.1053\/j.semnuclmed.2008.12.004","type":"journal-article","created":{"date-parts":[[2009,4,1]],"date-time":"2009-04-01T08:45:18Z","timestamp":1238575518000},"page":"195-203","source":"Crossref","is-referenced-by-count":3,"title":["Interventional Nuclear Brain Imaging"],"prefix":"10.1053","volume":"39","author":[{"given":"David K.","family":"Leung","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald L.","family":"Van Heertum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1053\/j.semnuclmed.2008.12.004_bib1","first-page":"255","article-title":"Pharmacologic interventions in nuclear medicine assessment of cardiac perfusion","volume":"4","author":"Matte","year":"2001","journal-title":"J Pharmacy Pharma Sci"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib2","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0001-2998(05)80052-2","article-title":"Interventions and functional brain imaging","volume":"21","author":"Yudd","year":"1991","journal-title":"Semin Nucl Med"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib3","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0741-5214(96)70097-6","article-title":"Value of single photon emission computerized imaging in the treatment of patients undergoing carotid endarterectomy","volume":"24","author":"Tawes","year":"1996","journal-title":"J Vasc Surg"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib4","doi-asserted-by":"crossref","first-page":"1828","DOI":"10.1007\/s00259-001-0656-6","article-title":"Cerebral perfusion and haemodynamics measured by SPET in symptom-free patients with transient ischaemic attack: Clinical implications","volume":"28","author":"Marti-Fabregas","year":"2001","journal-title":"Eur J Nucl Med"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib5","first-page":"221","article-title":"Nuclear medicine in the rehabilitative treatment evaluation in stroke recovery","volume":"43","author":"Mountz","year":"2007","journal-title":"Eura Medicophys"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib6","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S1056-8727(99)00044-6","article-title":"Cerebrovascular reactivity and reserve capacity in type II diabetes mellitus","volume":"13","author":"F\u00fclesdi","year":"1999","journal-title":"J Diabetes Complications"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib7","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1161\/01.STR.17.6.1291","article-title":"Evaluation of the cerebral vasodilatory capacity by the acetazolamide test before EC-IC bypass surgery in patients with occlusion of the internal carotid artery","volume":"17","author":"Vorstrup","year":"1986","journal-title":"Stroke"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib8","doi-asserted-by":"crossref","first-page":"458","DOI":"10.3348\/kjr.2007.8.6.458","article-title":"Assessment of cerebrovascular reserve before and after STA-MCA bypass surgery by SPECT and SPM analysis","volume":"8","author":"O","year":"2007","journal-title":"Korean J Radiol"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib9","first-page":"237","article-title":"Single-photon emission computed tomography in neurotherapeutics","volume":"2","author":"Devous","year":"2005","journal-title":"J Am Soc Exp NeuroTher"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib10","first-page":"465","article-title":"Imaging of cerebral blood flow-to-volume distribution using SPECT","volume":"27","author":"Knapp","year":"1986","journal-title":"J Nucl Med"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib11","first-page":"32","article-title":"Carbon dioxide reactivity by consecutive Technetium-99m-HMPAO SPECT in patients with a chronically obstructed major cerebral artery","volume":"35","author":"Oki","year":"1994","journal-title":"J Nucl Med"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib12","doi-asserted-by":"crossref","unstructured":"Fallon BA, Lipkin RB, Corbera KM, et al: Regional cerebral blood flow and metabolic rate in persistent Lyme encephalopathy. Arch Gen Psychiatry (in press)","DOI":"10.1001\/archgenpsychiatry.2009.29"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib13","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1176\/jnp.15.3.326","article-title":"Regional cerebral blood flow and cognitive deficits in chronic Lyme disease","volume":"15","author":"Fallon","year":"2003","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib14","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1148\/radiology.182.2.1732965","article-title":"Carotid artery disease: evaluation with acetazolamide-enhanced Tc-99m HMPAO SPECT","volume":"182","author":"Burt","year":"1992","journal-title":"Radiology"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib15","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/j.1748-1716.1983.tb07202.x","article-title":"Acute effects of acetazolamide on cerebral blood flow in man","volume":"117","author":"Hauge","year":"1983","journal-title":"Acta Physiol Scand"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib16","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1097\/00006231-199612000-00008","article-title":"Vasoreactive effect of acetazolamide as a function of time with sequential PET 15O-water measurement","volume":"17","author":"Hayashida","year":"1996","journal-title":"Nucl Med Commun"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib17","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1161\/01.STR.26.9.1572","article-title":"Effect of adenosine on cerebral blood flow as evaluated by single-photon emission computed tomography in normal subjects and in patients with occlusive carotid disease: a comparison with acetazolamide","volume":"26","author":"Soricelli","year":"1995","journal-title":"Stroke"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib18","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/BF01401867","article-title":"Prediction of cerebral infarction due to vasospasm following aneurysmal subarachnoid haemorrhage using acetazolamide-activated 123-I-IMP SPECT","volume":"123","author":"Kimura","year":"1993","journal-title":"Acta Neurochir"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib19","first-page":"253","article-title":"Presymptomatic detection of ischemia from vasospasm after subarachnoid hemorrhage with acetazolamide-activated SPECT","volume":"28","author":"Mayer","year":"1997","journal-title":"Stroke"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib20","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.surneu.2004.12.017","article-title":"Low cerebrovascular reserve capacity in long-term follow-up after subarachnoid hemorrhage","volume":"64","author":"Reinprecht","year":"2005","journal-title":"Surg Neurol"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib21","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S1052-3057(99)80057-3","article-title":"Interventional endovascular therapy: SPECT cerebral blood flow imaging compared with transcranial Doppler monitoring of balloon angioplasty and intraarterial papaverine for cerebral vasospasm","volume":"8","author":"Lewis","year":"1999","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib22","first-page":"1865","article-title":"Adaptive changes of autoregulation in chronic cerebral hypotension with arteriovenous malformations: An acetazolamide-enhanced single-photon emission CT study","volume":"16","author":"Hacein-Bey","year":"1995","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib23","first-page":"1110","article-title":"Adenosine technetium-99m-methoxy isobutyl isonitrile myocardial tomography in patients with coronary artery disease: comparison with exercise","volume":"35","author":"Cuocolo","year":"1994","journal-title":"J Nucl Med"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib24","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1177\/014107689108400315","article-title":"Modern treatment strategies for patients with epilepsy: a review","volume":"84","author":"Duncan","year":"1991","journal-title":"J R Soc Med"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib25","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1017\/S0317167100052185","article-title":"Surgical treatment of epilepsy in pediatric patients","volume":"27","author":"Wyllie","year":"2000","journal-title":"Can J Neurol Sci"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib26","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1053\/snuc.2003.127301","article-title":"Positron emission tomography and single photon emission computed tomography in epilepsy care","volume":"33","author":"Henry","year":"2003","journal-title":"Semin Nucl Med"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib27","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1111\/j.1528-1167.2005.06705.x","article-title":"Localizing value of ictal-interictal SPECT analyzed by SPM (ISAS)","volume":"46","author":"McNally","year":"2005","journal-title":"Epilepsia"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib28","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1684\/epd.2007.0070","article-title":"Multimodality imaging for focus localization in pediatric pharmacoresistant epilepsy","volume":"9","author":"Kurian","year":"2007","journal-title":"Epileptic Disord"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib29","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1007\/s00381-006-0137-0","article-title":"Functional neuroimaging in the preoperative evaluation of children with drug-resistant epilepsy","volume":"22","author":"Sood","year":"2006","journal-title":"Child Nervous Syst"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib30","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1212\/01.wnl.0000310432.92489.90","article-title":"Functional imaging in Parkinson disease","volume":"70","author":"Nandhagopal","year":"2008","journal-title":"Neurology"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib31","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1136\/jnnp.67.6.737","article-title":"Usefulness of a dopamine transporter PET ligand [18F]beta-CFT in assessing disability in Parkinson's disease","volume":"67","author":"Rinne","year":"1999","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib32","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1097\/00006231-200505000-00005","article-title":"123I-FP-CIT semi-quantitative SPECT detects preclinical bilateral dopaminergic deficit in early Parkinson's disease with unilateral symptoms","volume":"26","author":"Filippi","year":"2005","journal-title":"Nucl Med Commun"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib33","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1038\/sj.jcbfm.9600358","article-title":"Abnormal metabolic network activity in Parkinson's disease: Test\u2013retest reproducibility","volume":"27","author":"Ma","year":"2007","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib34","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1602\/neurorx.2.2.361","article-title":"Neuroimaging and therapeutics in movement disorders","volume":"2","author":"Eckert","year":"2005","journal-title":"NeuroRx"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib35","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0166-2236(90)90110-V","article-title":"Primate models of movement disorders of basal ganglia origin","volume":"13","author":"DeLong","year":"1990","journal-title":"Trends Neurosci"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib36","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.1212\/WNL.57.11.2083","article-title":"Metabolic correlates of levodopa response in Parkinson's disease","volume":"57","author":"Feigin","year":"2001","journal-title":"Neurology"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib37","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1002\/mds.1212","article-title":"Resting regional cerebral glucose metabolism in advanced Parkinson's disease studied in the off and on conditions with [18F]FDG-PET","volume":"16","author":"Berding","year":"2001","journal-title":"Mov Disord"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib38","doi-asserted-by":"crossref","first-page":"4563","DOI":"10.1523\/JNEUROSCI.22-11-04563.2002","article-title":"Defining the neural mechanisms of probabilistic reversal learning using event-related functional magnetic resonance imaging","volume":"22","author":"Cools","year":"2002","journal-title":"J Neurosci"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib39","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1093\/brain\/122.8.1469","article-title":"Specific cognitive deficits in mild frontal variant frontotemporal dementia","volume":"122","author":"Rahman","year":"1999","journal-title":"Brain"},{"issue":"suppl 3","key":"10.1053\/j.semnuclmed.2008.12.004_bib40","first-page":"III44","article-title":"Do patients with Parkinson's disease benefit from embryonic dopamine cell transplantation?","volume":"250","author":"Freed","year":"2003","journal-title":"J Neurol"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib41","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1001\/archneur.1963.00460010024002","article-title":"Variation in form of circle of Willis","volume":"8","author":"Riggs","year":"1963","journal-title":"Arch Neurol"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib42","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1148\/radiol.2351031799","article-title":"Distribution of cerebral blood flow in the Circle of Willis","volume":"235","author":"Hendrikse","year":"2005","journal-title":"Radiology"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib43","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1161\/01.STR.15.5.846","article-title":"Cerebral aneurysms and variations in the Circle of Willis","volume":"15","author":"Kayembe","year":"1984","journal-title":"Stroke"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib44","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1148\/radiol.2313030093","article-title":"Carotid perfusion CT with balloon occlusion and acetazolamide challenge test: Feasibility","volume":"231","author":"Jain","year":"2004","journal-title":"Radiology"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib45","first-page":"1243","article-title":"SPECT HMPAO and balloon test occlusion: Interest in predicting tolerance prior to permanent cerebral artery occlusion","volume":"34","author":"Askienazy","year":"1993","journal-title":"J Nucl Med"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib46","first-page":"1616","article-title":"Usefulness of brain SPECT to evaluate brain tolerance and hemodynamic changes during temporary balloon occlusion test and after permanent carotid occlusion","volume":"43","author":"Sugawara","year":"2002","journal-title":"J Nucl Med"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib47","first-page":"415","article-title":"Brain perfusion imaging during preoperative temporary balloon occlusion of the internal carotid artery","volume":"37","author":"Lorberboym","year":"1996","journal-title":"J Nucl Med"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib48","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1227\/00006123-198709000-00002","article-title":"Common carotid occlusion for unclippable carotid aneurysms: An old but still effective operation","volume":"21","author":"Swearingen","year":"1987","journal-title":"Neurosurgery"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib49","doi-asserted-by":"crossref","first-page":"37","DOI":"10.2176\/nmc.45.37","article-title":"Combined surgical and endovascular treatment of infected pseudoaneurysm after carotid endarterectomy","volume":"45","author":"Yasuda","year":"2005","journal-title":"Neurol Med Chir"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib50","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1164\/rccm.2109080","article-title":"Epidemiology of obstructive sleep apnea: a population health perspective","volume":"165","author":"Young","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib51","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1164\/rccm.200201-050OC","article-title":"Brain morphology associated with obstructive sleep apnea","volume":"166","author":"Macey","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib52","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1164\/rccm.200406-738OC","article-title":"Cerebral structural changes in severe obstructive sleep apnea","volume":"171","author":"O'Donoghue","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib53","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.sleep.2007.03.006","article-title":"Neuroimaging in sleep medicine","volume":"8","author":"Dang-Vu","year":"2007","journal-title":"Sleep Med"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib54","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1093\/sleep\/30.11.1515","article-title":"Reduced cerebral blood flow during wakefulness in obstructive sleep apnea-hypopnea syndrome","volume":"30","author":"Joo","year":"2007","journal-title":"Sleep"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib55","first-page":"926","article-title":"Changes in regional CNS perfusion in obstructive sleep apnea syndrome: Initial SPECT studies with injected nocturnal 99mTc-HMPAO","volume":"51","author":"Ficker","year":"1997","journal-title":"Pneumologie"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib56","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1093\/brain\/124.8.1601","article-title":"Networks mediating the clinical effects of pallidal brain stimulation for Parkinson's disease: A PET study of resting-state glucose metabolism","volume":"124","author":"Fukuda","year":"2001","journal-title":"Brain"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib57","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1097\/01.WCB.0000092831.44769.09","article-title":"Subthalamic nucleus stimulation restores glucose metabolism in associative and limbic cortices and in cerebellum: Evidence from a FDG-PET study in advanced Parkinson's disease","volume":"24","author":"Hilker","year":"2004","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib58","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.neuroimage.2005.12.024","article-title":"Network modulation by the subthalamic nucleus in the treatment of Parkinson's disease","volume":"31","author":"Trost","year":"2006","journal-title":"NeuroImage"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib59","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s00429-008-0189-x","article-title":"Brain structural and functional abnormalities in mood disorders: Implications for neurocircuitry models of depression","volume":"213","author":"Drevets","year":"2008","journal-title":"Brain Structure and Function"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib60","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0165-0327(00)00200-7","article-title":"Study of the influence of electroconvulsive therapy on the regional cerebral blood flow by HMPAO-SPECT","volume":"65","author":"Elizagarate","year":"2001","journal-title":"J Affect Disord"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib61","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1176\/appi.ajp.158.2.305","article-title":"Decreased regional brain metabolism after ECT","volume":"158","author":"Nobler","year":"2001","journal-title":"Am J Psychiatry"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib62","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1097\/00124509-199903000-00004","article-title":"EEG correlates of the response to ECT: A possible antidepressant role of brain-derived neurotrophic factor","volume":"15","author":"Krystal","year":"1999","journal-title":"J ECT"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib63","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1001\/archpsyc.1996.01830090060009","article-title":"The effects of electroconvulsive therapy on quantitative electroencephalograms: Relationship to clinical outcome","volume":"53","author":"Sackeim","year":"1996","journal-title":"Arch Gen Psychiatry"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib64","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1001\/archpsyc.1994.03950110044007","article-title":"Regional cerebral blood flow in mood disorders, III","volume":"51","author":"Nobler","year":"1994","journal-title":"Arch Gen Psychiatry"},{"issue":"3 suppl 2","key":"10.1053\/j.semnuclmed.2008.12.004_bib65","doi-asserted-by":"crossref","first-page":"S69","DOI":"10.1097\/00002093-200607001-00010","article-title":"Cognitive reserve and Alzheimer disease","volume":"20","author":"Stern","year":"2006","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib66","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1212\/WNL.55.9.1291","article-title":"Different brain networks mediate task performance in normal aging and AD: Defining compensation","volume":"55","author":"Stern","year":"2000","journal-title":"Neurology"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib67","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1002\/ana.21212","article-title":"Cognitive reserve hypothesis: Pittsburgh Compound B and fluorodeoxyglucose positron emission tomography in relation to education in mild Alzheimer's disease","volume":"63","author":"Kemppainen","year":"2008","journal-title":"Ann Neurol"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib68","first-page":"608","article-title":"Hypofrontality and negative symptoms in major depressive disorder","volume":"39","author":"Galynker","year":"1998","journal-title":"J Nucl Med"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib69","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.maturitas.2007.09.014","article-title":"Reduced frontal perfusion in depressed postmenopausal women: A SPECT study with WCST","volume":"59","author":"Yao","year":"2008","journal-title":"Maturitas"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib70","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1017\/S0033291700036151","article-title":"Changes in regional cerebral blood flow on recovery from depression","volume":"25","author":"Bench","year":"1995","journal-title":"Psychol Med"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib71","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1046\/j.1440-1819.2002.00924.x","article-title":"The relationship between regional cerebral blood flow and the Wisconsin Card Sorting Test in negative schizophrenia","volume":"56","author":"Liu","year":"2002","journal-title":"Psychiatry Clin Neurosci"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib72","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1192\/bjp.177.3.222","article-title":"Changes in regional cerebral blood flow due to cognitive activation among patients with schizophrenia","volume":"177","author":"Toone","year":"2000","journal-title":"Br J Psychiatry"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib73","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/S0166-2236(84)80062-4","article-title":"CNS stimulants as tools in the study of schizophrenia","volume":"7","author":"Angrist","year":"1984","journal-title":"Trends Neurosci"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib74","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1176\/jnp.8.2.223","article-title":"Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs","volume":"8","author":"Creese","year":"1996","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib75","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1176\/ajp.155.6.761","article-title":"Increased striatal dopamine transmission in schizophrenia: Confirmation in a second cohort","volume":"155","author":"Abi-Dargham","year":"1998","journal-title":"Am J Psychiatry"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib76","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1073\/pnas.94.6.2569","article-title":"Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: Evidence from a novel positron emission tomography method","volume":"94","author":"Breier","year":"1997","journal-title":"Proc Natl Acad Sci"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib77","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1002\/(SICI)1098-2396(199806)29:2<142::AID-SYN5>3.0.CO;2-7","article-title":"Effects of NMDA antagonism on striatal dopamine release in healthy subjects: Application of a novel PET approach","volume":"29","author":"Breier","year":"1998","journal-title":"Synapse"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib78","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/S0006-3223(00)00976-8","article-title":"Modulation of amphetamine-induced striatal dopamine release by ketamine in humans: Implications for schizophrenia","volume":"48","author":"Kegeles","year":"2000","journal-title":"Biol Psychiatry"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib79","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1038\/sj.npp.1300902","article-title":"Modulation of amphetamine-induced dopamine release by group II metabotropic glutamate receptor agonist LY354740 in non-human primates studied with positron emission tomography","volume":"31","author":"van Berckel","year":"2006","journal-title":"Neuropsychopharmacology"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib80","first-page":"1465","article-title":"In vivo quantification of brain serotonin transporters in humans using [11C]McN 5652","volume":"41","author":"Parsey","year":"2000","journal-title":"J Nucl Med"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib81","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1001\/archpsyc.60.4.386","article-title":"High levels of serotonin transporter occupancy with low-dose clomipramine in comparative occupancy study with fluvoxamine using positron emission tomography","volume":"60","author":"Suhara","year":"2003","journal-title":"Arch Gen Psychiatry"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib82","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0924-977X(98)00013-3","article-title":"In vivo visualization of serotonin transporters in the human brain during fluoxetine treatment","volume":"9","author":"Tauscher","year":"1999","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib83","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1176\/appi.ajp.158.11.1843","article-title":"Occupancy of serotonin transporters by paroxetine and citalopram during treatment of depression: A [11C]DASB PET imaging study","volume":"158","author":"Meyer","year":"2001","journal-title":"Am J Psychiatry"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib84","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1016\/S0278-5846(99)00051-2","article-title":"Single photon emission computed tomography of the brain with Tc-99m HMPAO during sumatriptan challenge in obsessive-compulsive disorder: Investigating the functional role of the serotonin auto-receptor","volume":"23","author":"Stein","year":"1999","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib85","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/S0278-5846(01)00334-7","article-title":"Functional brain imaging and pharmacotherapy in trichotillomania","volume":"26","author":"Stein","year":"2002","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib86","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/1471-244X-4-30","article-title":"Single photon emission computed tomography (SPECT) of anxiety disorders before and after treatment with citalopram","volume":"4","author":"Carey","year":"2004","journal-title":"BMC Psychiatry"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib87","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1176\/jnp.14.3.340","article-title":"SPECT scans in identical twins with trichotillomania","volume":"14","author":"Vythilingum","year":"2002","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib88","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0278-5846(99)00109-8","article-title":"Functional brain imaging and pharmacotherapy in social phobia: Single photon emission computed tomography before and after treatment with the selective serotonin reuptake inhibitor citalopram","volume":"24","author":"Van der Linden","year":"2000","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib89","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1001\/archpsyc.60.11.1145","article-title":"Regulation of human affective responses by anterior cingulate and limbic mu-opioid neurotransmission","volume":"60","author":"Zubieta","year":"2003","journal-title":"Arch Gen Psychiatry"},{"key":"10.1053\/j.semnuclmed.2008.12.004_bib90","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1001\/archpsyc.61.1.73","article-title":"Mood disturbances and regional cerebral metabolic abnormalities in recently abstinent methamphetamine abusers","volume":"61","author":"London","year":"2004","journal-title":"Arch Gen Psychiatry"}],"container-title":["Seminars in Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001299808001542?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001299808001542?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,8]],"date-time":"2025-02-08T19:58:22Z","timestamp":1739044702000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0001299808001542"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5]]},"references-count":90,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,5]]}},"alternative-id":["S0001299808001542"],"URL":"https:\/\/doi.org\/10.1053\/j.semnuclmed.2008.12.004","relation":{},"ISSN":["0001-2998"],"issn-type":[{"value":"0001-2998","type":"print"}],"subject":[],"published":{"date-parts":[[2009,5]]}}}