{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T22:46:07Z","timestamp":1789685167177,"version":"4.0.1"},"reference-count":138,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T00:00:00Z","timestamp":1748995200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004271","name":"Sapienza Universit\u00e0 di Roma","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004271","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Nuclear Medicine"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1053\/j.semnuclmed.2025.06.002","type":"journal-article","created":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T19:24:31Z","timestamp":1750101871000},"page":"512-525","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Neuroimaging of Mild Traumatic Injury"],"prefix":"10.1053","volume":"55","author":[{"given":"Gabriela","family":"Capriotti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessia","family":"Guarnera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Romano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Moltoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgia","family":"Granese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8865-0723","authenticated-orcid":false,"given":"Alessando","family":"Bozzao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Signore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1053\/j.semnuclmed.2025.06.002_bib0001","article-title":"Neuroimaging of traumatic brain injury","volume":"7","author":"Douglas","year":"2018","journal-title":"Med Sci"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0002","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.csm.2010.08.009","article-title":"Biomechanics of concussion","volume":"30","author":"Meaney","year":"2011","journal-title":"Clin Sports Med"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0003","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/B978-0-444-52892-6.00004-0","article-title":"The neuropathology of traumatic brain injury","volume":"127","author":"Mckee","year":"2015","journal-title":"Handb Clin Neurol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0004","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1089\/neu.2013.3306","article-title":"A review of the effectiveness of neuroimaging modalities for the detection of traumatic brain injury","volume":"32","author":"Amyot","year":"2015","journal-title":"J Neurotrauma"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0005","first-page":"1551","article-title":"Glasgow coma scale","volume":"79","author":"Jones","year":"1979","journal-title":"Am J Nurs"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0006","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1111\/j.1750-3639.1995.tb00618.x","article-title":"The nature, distribution and causes of traumatic brain injury","volume":"5","author":"Graham","year":"1995","journal-title":"Brain Pathol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0007","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/B978-0-444-52892-6.00002-7","article-title":"Classification of traumatic brain injury: past, present, and future","volume":"127","author":"Hawryluk","year":"2015","journal-title":"Handb Clin Neurol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0008","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.ncl.2008.02.001","article-title":"Management of traumatic brain injury in the intensive care unit","volume":"26","author":"Ling","year":"2008","journal-title":"Neurol Clin"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0009","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0140-6736(74)91639-0","article-title":"Assessment of coma and impaired con-sciousness. A practical scale","volume":"2","author":"Teasdale","year":"1974","journal-title":"Lancet"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0010","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1007\/s00259-020-04926-4","article-title":"A critical review of radiotracers in the positron emission tomography imaging of traumatic brain injury: FDG, tau, and amyloid imaging in mild traumatic brain injury and chronic traumatic encephalopathy","volume":"48","author":"Ayubcha","year":"2021","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0011","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.nec.2016.05.005","article-title":"Concussion\u2014Mild traumatic brain injury: recoverable injury with potential for serious sequelae","volume":"27","author":"Kamins","year":"2016","journal-title":"Neurosurg Clin"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0012","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1089\/neu.1994.11.173","article-title":"Ultrastructural studies of diffuse axonal injury in humans","volume":"11","author":"Christman","year":"1994","journal-title":"J Neurotrauma"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0013","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1227\/NEU.0000000000000505","article-title":"The new neurometabolic cascade of concussion","volume":"75","author":"Giza","year":"2014","journal-title":"Neurosurgery"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0014","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/0006-8993(91)90755-K","article-title":"Dynamic changes in local cerebral glucose utilization following cerebral concussion in rats: evidence of a hyper-and subsequent hypometabolic state","volume":"561","author":"Yoshino","year":"1991","journal-title":"Brain Res"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0015","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.nicl.2017.02.015","article-title":"The first week after concussion: blood flow, brain function and white matter microstructure","volume":"14","author":"Churchill","year":"2017","journal-title":"Neuroimage Clin"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0016","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1002\/ana.22455","article-title":"Inflammation after trauma: microglial activation and traumatic brain injury","volume":"70","author":"Ramlackhansingh","year":"2011","journal-title":"Ann Neurol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0017","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1093\/brain\/aws322","article-title":"Inflammation and white matter degeneration persist for years after a single traumatic brain injury","volume":"136","author":"Johnson","year":"2013","journal-title":"Brain"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0018","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1620\/tjem.221.229","article-title":"Distinct time courses of secondary brain damage in the hippocampus following brain concussion and contusion in rats","volume":"221","author":"Nakajima","year":"2010","journal-title":"Tohoku J Exp Med"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0019","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.neuroscience.2016.01.022","article-title":"Blast exposure causes dynamic microglial\/macrophage responses and microdomains of brain microvessel dysfunction","volume":"319","author":"Huber","year":"2016","journal-title":"Neuroscience"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0020","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1148\/radiol.2021203071","article-title":"Susceptibility-weighted imaging: technical essentials and clinical neurologic applications","volume":"299","author":"Haller","year":"2021","journal-title":"Radiology"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0021","first-page":"580","article-title":"Susceptibility-weighted MRI in mild traumatic brain injury: the importance of cerebral microbleeds","volume":"84","author":"Ying-Chi Tseng","year":"2015","journal-title":"J Neurol Neurophysiol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0022","doi-asserted-by":"crossref","first-page":"338","DOI":"10.3174\/ajnr.A1355","article-title":"MR imaging detection of cerebral microbleeds: effect of susceptibility-weighted imaging, section thickness, and field strength","volume":"30","author":"Nandigam","year":"2009","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0023","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s00062-012-0185-7","article-title":"Comparison of ESWAN, SWI-SPGR, and 2D T2*-weighted GRE sequence for depicting cerebral microbleeds","volume":"23","author":"Guo","year":"2013","journal-title":"Clin Neuroradiol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0024","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1007\/s00330-013-3061-1","article-title":"Comparison of 3D multi-echo gradient-echo and 2D T2* MR sequences for the detection of arterial thrombus in patients with acute stroke","volume":"24","author":"Hodel","year":"2014","journal-title":"Eur Radiol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0025","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S1474-4422(09)70013-4","article-title":"Cerebral microbleeds: a guide to detection and interpretation","volume":"8","author":"Greenberg","year":"2009","journal-title":"Lancet Neurol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0026","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1212\/WNL.0000000000001237","article-title":"Susceptibility-weighted MRI in mild traumatic brain injury","volume":"84","author":"Huang","year":"2015","journal-title":"Neurology"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0027","doi-asserted-by":"crossref","first-page":"99","DOI":"10.3174\/ajnr.A2250","article-title":"Cerebral microhemorrhages detected by susceptibility-weighted imaging in amateur boxers","volume":"32","author":"Hasiloglu","year":"2011","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0028","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3171\/2012.9.FOCUS12287","article-title":"A prospective study of physician-observed concussion during a varsity university ice hockey season: incidence and neuropsychological changes. Part 2 of 4","volume":"33","author":"Echlin","year":"2012","journal-title":"Neurosurg Focus"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0029","doi-asserted-by":"crossref","first-page":"365","DOI":"10.3340\/jkns.2009.46.4.365","article-title":"Detection of traumatic cerebral microbleeds by susceptibility-weighted image of MRI","volume":"46","author":"Park","year":"2009","journal-title":"J Korean Neurosurg Soc"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0030","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1007\/s00234-017-1898-8","article-title":"The association between microhaemorrhages and post - traumatic functional outcome in the chronic phase after mild traumatic brain injury","volume":"59","author":"de Haan","year":"2017","journal-title":"Neuroradiol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0031","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.bbr.2017.02.039","article-title":"Both hemorrhagic and non-hemorrhagic traumatic MRI lesions are associated with the microstructural damage of the normal appearing white matter","volume":"340","author":"Toth","year":"2018","journal-title":"Behav Brain Res"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0032","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1007\/s10072-014-1788-3","article-title":"Microbleeds on susceptibility-weighted MRI in depressive and non-depressive patients after mild traumatic brain injury","volume":"35","author":"Wang","year":"2014","journal-title":"Neurol Sci"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0033","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1016\/j.pjnns.2018.08.011","article-title":"Central nervous system microbleeds in the acute phase are associated with structural integrity by DTI one year after mild traumatic brain injury: a longitudinal study","volume":"52","author":"Studerus-Germann","year":"2018","journal-title":"Neurol Neurochir Pol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0034","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1089\/neu.2013.3021","article-title":"Detecting lesions after traumatic brain injury using susceptibility weighted imaging: a comparison with fluid-attenuated inversion recovery and correlation with clinical outcome","volume":"30","author":"Spitz","year":"2013","journal-title":"J Neurotrauma"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0035","doi-asserted-by":"crossref","first-page":"3172","DOI":"10.1089\/neu.2018.6360","article-title":"Patients with mild traumatic brain injury recruited from both hospital and primary care settings: a controlled longitudinal Magnetic resonance imaging study","volume":"36","author":"Einarsen","year":"2019","journal-title":"J Neurotrauma"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0036","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1093\/neuros\/nyx103","article-title":"Current clinical brain tumor imaging","volume":"81","author":"Villanueva-Meyer","year":"2017","journal-title":"Neurosurgery"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0037","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1002\/mrm.27742","article-title":"Methodological consensus on clinical proton MRS of the brain: review and recommendations","volume":"82","author":"Wilson","year":"2019","journal-title":"Magn Reson Med"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0038","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/978-1-61737-992-5_9","article-title":"MR spectroscopy and spectroscopic imaging of the brain","volume":"711","author":"Zhu","year":"2011","journal-title":"Method Mol Biol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0039","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1089\/neu.2022.0125","article-title":"Magnetic resonance spectroscopy of traumatic brain injury and subconcussive hits: a systematic review and meta- analysis","volume":"39","author":"Joyce","year":"2022","journal-title":"J Neurotrauma"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0040","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1080\/13803395.2015.1077930","article-title":"Cognitive-motor dysfunction after severe traumatic brain injury: a cerebral interhemispheric disconnection syndrome","volume":"37","author":"Falchook","year":"2015","journal-title":"J Clin Exp Neuropsychol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0041","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1089\/08977150152693683","article-title":"N-acetylaspartate reduction as a measure of injury severity and mitochondrial dysfunction following diffuse traumatic brain injury","volume":"18","author":"Signoretti","year":"2001","journal-title":"J Neurotrauma"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0042","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/neu.2013.3079","article-title":"A systematic review of proton magnetic resonance spectroscopy findings in sport-related concussion","volume":"31","author":"Gardner","year":"2014","journal-title":"J Neurotrauma"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0043","doi-asserted-by":"crossref","first-page":"3232","DOI":"10.1093\/brain\/awq200","article-title":"Assessment of metabolic brain damage and recovery following mild traumatic brain injury: a multicentre, proton magnetic resonance spectroscopic study in concussed patients","volume":"133","author":"Vagnozzi","year":"2010","journal-title":"Brain"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0044","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1089\/neu.2004.21.1693","article-title":"Proton MRS in acute traumatic brain injury: role for glutamate\/glutamine and choline for outcome prediction","volume":"21","author":"Shutter","year":"2004","journal-title":"J Neurotrauma"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0045","first-page":"1286","article-title":"Temporal window of metabolic brain vulnerability to concussion: a pilot 1H-magnetic resonance spectroscopic study in concussed athletes\u2013part III","volume":"62","author":"Vagnozzi","year":"2008","journal-title":"Neurosurgery"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0046","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1097\/HTR.0b013e3182795045","article-title":"Decrease in N-acetylaspartate following concussion may be coupled to decrease in creatine","volume":"28","author":"Vagnozzi","year":"2013","journal-title":"J Head Trauma Rehabil"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0047","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1007\/s00247-005-1441-7","article-title":"Elevated lactate as an early marker of brain injury in inflicted traumatic brain injury","volume":"35","author":"Makoroff","year":"2005","journal-title":"Pediatr Radiol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0048","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3171\/2019.9.FOCUS19652","article-title":"Advanced neuroimaging in traumatic brain injury: an overview","volume":"47","author":"Smith","year":"2019","journal-title":"Neurosurg Focus"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0049","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.nic.2017.09.009","article-title":"Diffusion MR imaging in mild traumatic brain injury","volume":"28","author":"Borja","year":"2018","journal-title":"Neuroimaging Clin N Am"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0050","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.nec.2010.11.004","article-title":"Diffusion tractography: methods, validation and applications in patients with neurosurgical lesions","volume":"22","author":"Leclercq","year":"2011","journal-title":"Neurosurg Clin N Am"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0051","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s11682-012-9156-5","article-title":"A review of magnetic resonance imaging and diffusion tensor imaging findings in mild traumatic brain injury","volume":"6","author":"Shenton","year":"2012","journal-title":"Brain Imaging Behav"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0052","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1097\/RMR.0b013e31823e65b8","article-title":"Mild traumatic brain injury: is diffusion imaging ready for primetime in forensic medicine?","volume":"21","author":"Grossman","year":"2010","journal-title":"Top Magn Reson Imaging"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0053","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1177\/1971400915598071","article-title":"Reversible restricted-diffusion lesion representing transient intramyelinic cytotoxic edema in a patient with traumatic brain injury","volume":"28","author":"Al Brashdi","year":"2015","journal-title":"Neuroradiol J"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0054","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1089\/neu.2005.22.857","article-title":"Diffusion-weighted imaging of edema following traumatic brain injury in rats: effects of secondary hypoxia","volume":"22","author":"Van Putten","year":"2005","journal-title":"J Neurotrauma"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0055","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1089\/neu.1995.12.555","article-title":"The pathobiology of traumatically induced axonal injury in animals and humans: a review of current thoughts","volume":"12","author":"Povlishock","year":"1995","journal-title":"J Neurotrauma"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0056","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1007\/s00234-006-0109-9","article-title":"Impaired cognitive functions in mild traumatic brain injury patients with normal and pathologic magnetic resonance imaging","volume":"48","author":"Kurca","year":"2006","journal-title":"Neuroradiology"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0057","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.neubiorev.2018.05.023","article-title":"The relationship between diffusion tensor imaging findings and cognitive outcomes following adult traumatic brain injury: a meta-analysis","volume":"92","author":"Wallace","year":"2018","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0058","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.1093\/brain\/awn247","article-title":"Structural dissociation of attentional control and memory in adults with and without mild traumatic brain injury","volume":"131","author":"Niogi","year":"2008","journal-title":"Brain"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0059","doi-asserted-by":"crossref","first-page":"6892","DOI":"10.1126\/sciadv.aaz6892","article-title":"The evolution of white matter microstructural changes after mild traumatic brain injury: a longitudinal DTI and NODDI study","volume":"6","author":"Palacios","year":"2020","journal-title":"Sci Adv"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0060","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1089\/neu.2021.0408","article-title":"Diffusion tensor imaging reveals elevated diffusivity of white matter microstructure that is independently associated with long-term outcome after mild traumatic brain injury: a TRACK-TBI study","volume":"39","author":"Palacios","year":"2022","journal-title":"J Neurotrauma"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0061","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.3174\/ajnr.A4851","article-title":"Bidirectional changes in anisotropy are associated with outcomes in mild traumatic brain injury","volume":"37","author":"Strauss","year":"2016","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0062","article-title":"Neuropathological mechanisms of mild traumatic brain injury: a perspective from multimodal Magnetic resonance imaging","volume":"16","author":"Liu","year":"2022","journal-title":"Front Neurosc"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0063","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1089\/neu.2013.3171","article-title":"Diffusion tensor imaging for outcome prediction in mild traumatic brain injury: a TRACK-TBI study","volume":"31","author":"Yuh","year":"2014","journal-title":"J Neurotrauma"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0064","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1002\/hbm.23072","article-title":"Longitudinal assessment of white matter abnormalities following sports-related concussion","volume":"37","author":"Meier","year":"2016","journal-title":"Hum Brain Mapp"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0065","first-page":"794","article-title":"Diffusion tensor MR imaging in diffuse axonal injury","volume":"23","author":"Arfanakis","year":"2002","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0066","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1089\/neu.2011.1836","article-title":"Acute and chronic changes in diffusivity measures after sports concussion","volume":"28","author":"Henry","year":"2011","journal-title":"J Neurotrauma"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0067","doi-asserted-by":"crossref","unstructured":"Jezzard P, Matthews PM, Smith SM. Functional Magnetic Resonance imaging: an introduction to methods: 2001.","DOI":"10.1093\/acprof:oso\/9780192630711.001.0001"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0068","series-title":"Introduction to functional magnetic resonance imaging: principles and techniques","author":"Buxton","year":"2002"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0069","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1212\/WNL.53.6.1300","article-title":"Brain activation during working memory 1 month after mild traumatic brain injury: a functional MRI study","volume":"53","author":"McAllister","year":"1999","journal-title":"Neurology"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0070","doi-asserted-by":"crossref","first-page":"3157","DOI":"10.2337\/dc14-1683","article-title":"Altered brain activation patterns under different working memory loads in patients with type 2 diabetes","volume":"37","author":"Chen","year":"2014","journal-title":"Diabetes Care"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0071","doi-asserted-by":"crossref","first-page":"4394","DOI":"10.1002\/hbm.22930","article-title":"A functional magnetic resonance imaging study of cognitive control and neurosensory deficits in mild traumatic brain injury","volume":"36","author":"Mayer","year":"2015","journal-title":"Hum Brain Mapp"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0072","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1089\/neu.2013.3052","article-title":"A functional magnetic resonance imaging study of working memory in youth after sports-related concussion: is it still working?","volume":"31","author":"Keightley","year":"2014","journal-title":"J Neurotrauma"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0073","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/neu.2015.3905","article-title":"Brain networks subserving emotion regulation and adaptation after mild traumatic brain injury","volume":"33","author":"van der Horn","year":"2016","journal-title":"J Neurotrauma"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0074","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.nicl.2013.12.009","article-title":"Neuroimaging after mild traumatic brain injury: review and meta-analysis","volume":"4","author":"Eierud","year":"2014","journal-title":"Neuroimage Clin"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0075","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1146\/annurev-psych-113011-143750","article-title":"Executive functions","volume":"64","author":"Diamond","year":"2013","journal-title":"Annu Rev Psychol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0076","first-page":"49","article-title":"The significance of the default mode network (DMN) in neurological and neuropsychiatric disorders: a review","volume":"89","author":"Mohan","year":"2016","journal-title":"Yale J Biol Med"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0077","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.nicl.2018.02.011","article-title":"Connectomic markers of symptom severity in sport-related concussion: whole-brain analysis of resting-state fMRI","volume":"18","author":"Churchill","year":"2018","journal-title":"Neuroimage Clin"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0078","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1177\/1971400920901706","article-title":"Alterations of connectivity patterns in functional brain networks in patients with mild traumatic brain injury: a longitudinal resting-state functional magnetic resonance imaging study","volume":"33","author":"Souza","year":"2020","journal-title":"Neuroradiol J"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0079","doi-asserted-by":"crossref","first-page":"2544","DOI":"10.1002\/acn3.50951","article-title":"Default mode network anatomy and function is linked to pediatric concussion recovery","volume":"12","author":"Iyer","year":"2019","journal-title":"Ann Clin Transl Neurol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0080","first-page":"228","article-title":"The neurometabolic cascade of concussion","volume":"36","author":"Giza","year":"2001","journal-title":"J. Athl. Train"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0081","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1053\/snuc.2002.29269","article-title":"Guest editorial: the conception of FDG-PET imaging","volume":"32","author":"Alavi","year":"2002","journal-title":"Semin Nucl Med"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0082","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1007\/s002590100626","article-title":"FDG-PET for clinical use","volume":"28","author":"Reske","year":"2001","journal-title":"Eur J Nucl Med"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0083","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3389\/fnene.2013.00013","article-title":"FDG-PET imaging in mild traumatic brain injury: a critical review","volume":"5","author":"Byrnes","year":"2014","journal-title":"Front Neuroenerg"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0084","first-page":"372","article-title":"Neuroimaging in traumatic brain imaging","volume":"2","author":"Lee","year":"2005","journal-title":"NeuroRx J Am Soc Exp Neurother"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0085","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.cpet.2024.09.002","article-title":"MRI, and PET imaging in patients with traumatic brain injury","volume":"20","author":"Patil","year":"2025","journal-title":"PET Clin"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0086","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1089\/neu.2018.5641","article-title":"Cerebral glucose metabolism in patients with chronic mental and cognitive sequelae after a single blunt mild traumatic brain injury without visible","volume":"36","author":"Komura","year":"2019","journal-title":"J Neurotrauma"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0087","first-page":"623","article-title":"Statistical image analysis of cerebral glucose","volume":"48","author":"Kato","year":"2021","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0088","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1089\/neu.2013.2952","article-title":"Neuroimaging, behavioral, and psychological sequelae of repetitive combined blast\/impact mild traumatic brain injury in Iraq and Afghanistan war veterans","volume":"31","author":"Petrie","year":"2014","journal-title":"J Neurotrauma"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0089","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1186\/s40478-021-01197-4","article-title":"Identifying degenerative effects of repetitive head trauma with neuroimaging: a clinically-oriented review","volume":"9","author":"Asken","year":"2021","journal-title":"Acta Neuropathol Commun"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0090","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3389\/fnene.2013.00013","article-title":"FDG-PET imaging in mild traumatic brain injury: a critical review","volume":"5","author":"Byrnes","year":"2014","journal-title":"Front Neuroenerg"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0091","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0070-2153(06)76003-3","article-title":"Aggregate prone proteins are cleared from the cytosol by autophagy: therapeutic implications","volume":"76","author":"Williams","year":"2006","journal-title":"Curr Top Dev Biol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0092","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.semcdb.2003.12.015","article-title":"Tau protein and neurodegeneration","volume":"15","author":"Goedert","year":"2004","journal-title":"Semin Cell Dev Biol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0093","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1038\/s41380-018-0342-8","article-title":"Tau PET imaging in neurodegenerative tauopathies\u2014still a challenge","volume":"1","author":"Leuzy","year":"2019","journal-title":"Mol Psychiatry"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0094","doi-asserted-by":"crossref","first-page":"2039","DOI":"10.1073\/pnas.1409952112","article-title":"In vivo characterization of chronic traumatic encephalopathy using [F-18] FDDNP PET brain imaging","volume":"112","author":"Barrio","year":"2015","journal-title":"Proc Natl Acad Sci"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0095","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1097\/00019442-200201000-00004","article-title":"Localization of neurofibrillary tangles and beta amyloid plaques in the brains of living patients with Alzheimer disease","volume":"10","author":"Shoghi-Jadid","year":"2002","journal-title":"Am J Geriatr Psychiatry"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0096","doi-asserted-by":"crossref","first-page":"79","DOI":"10.3233\/JAD-171152","article-title":"FDDNP-PET tau brain protein binding patterns in military personnel with suspected chronic traumatic encephalopathy1","volume":"65","author":"Chen","year":"2018","journal-title":"J Alzheimers Dis"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0097","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.jagp.2012.11.019","article-title":"PET scanning of brain tau in retired national football league players: preliminary ndings","volume":"21","author":"Small","year":"2013","journal-title":"Am J Ger- iatr Psychiatry"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0098","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1093\/neuros\/nyx536","article-title":"Postmortem autopsy-confirmation of antemortem [F-18]FDDNP-PET scans in a football player with chronic traumatic encephalopathy","volume":"82","author":"Omalu","year":"2018","journal-title":"Neurosurgery"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0099","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.jalz.2014.04.013","article-title":"In vivo tau imaging: obstacles and progress","volume":"10","author":"Villemagne","year":"2014","journal-title":"Alzheimers Dement"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0100","doi-asserted-by":"crossref","first-page":"RC189","DOI":"10.1523\/JNEUROSCI.21-24-j0004.2001","article-title":"Binding characteristics of radiofluorinated 6- dialkylamino-2-naphthylethylidene derivatives as positron emission tomography imaging probes for \u03b2-amyloid plaques in Alzheimer's disease","volume":"21","author":"Agdeppa","year":"2001","journal-title":"J Neurosci"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0101","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1017\/cjn.2014.15","article-title":"Developments in tau PET imaging","volume":"41","author":"Zimmer","year":"2014","journal-title":"Can J Neurol Sci"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0102","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3390\/biom6010007","article-title":"Characteristics of tau and its ligands in PET imaging","volume":"6","author":"Harada","year":"2016","journal-title":"Biomolecules"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0103","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1007\/s00259-020-05156-4","article-title":"Clinical validity of second-generation tau PET tracers as biomarkers for Alzheimer's disease in the context of a structured 5-phase development framework","volume":"48","author":"Bischof","year":"2021","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0104","first-page":"2019","article-title":"In vivo detection of cerebral tau pathology in long-term survivors of traumatic brain injury","volume":"11","author":"Gorgoraptis","year":"1993","journal-title":"Sci Transl Med"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0105","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1056\/NEJMoa1900757","article-title":"Tau positron-emission tomography in former national football league players","volume":"380","author":"Stern","year":"2019","journal-title":"N Engl Med"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0106","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1002\/alz.13602","article-title":"Flortaucipir tau PET findings from former professional and college American football players in the DIAGNOSE CTE research project Alzheimers","volume":"20","author":"Su","year":"2024","journal-title":"Dement J Alzheimers Assoc"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0107","doi-asserted-by":"crossref","first-page":"e900","DOI":"10.1038\/tp.2016.175","article-title":"Cerebral [(18) F]T807\/AV1451 retention pattern in clinically probable CTE resembles pathognomonic distribution of CTE tauopathy","volume":"6","author":"Dickstein","year":"2016","journal-title":"Transl Psychiatry"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0108","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1001\/jamaneurol.2019.4509","article-title":"Tau positron emission tomographic findings in a former US football player with pathologically confirmed chronic traumatic encephalopathy","volume":"77","author":"Mantyh","year":"2020","journal-title":"JAMA Neurol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0109","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s40478-019-0686-6","article-title":"Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue","volume":"7","author":"Aguero","year":"2019","journal-title":"Acta Neuropathol Comm"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.nicl.2019.102025","article-title":"Tau PET and multimodal brain imaging in patients at risk for chronic traumatic encephalopathy","volume":"24","author":"Lesman-Segev","year":"2019","journal-title":"NeuroImage Clin"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0111","doi-asserted-by":"crossref","first-page":"3265","DOI":"10.1093\/brain\/awz238","article-title":"PET-detectable tau pathology correlates with long-term neuropsychiatric outcomes in patients with traumatic brain injury","volume":"142","author":"Takahata","year":"2019","journal-title":"Brain"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0112","doi-asserted-by":"crossref","DOI":"10.1016\/j.nicl.2021.102665","article-title":"Tau aggregation and increased neuroinflammation in athletes after sports-related concussions and in traumatic brain injury patients - a PET\/MR study","volume":"30","author":"Marklund","year":"2021","journal-title":"NeuroImage Clin"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0113","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1038\/nrn2808","article-title":"Traumatic brain injury and amyloid-\u03b2 pathology: a link to Alzheimer\u2019s disease","volume":"11","author":"Johnson","year":"2010","journal-title":"Nat Rev Neurosci"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0114","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.expneurol.2012.01.013","article-title":"Axonal pathology in traumatic brain injury","volume":"246","author":"Johnson","year":"2013","journal-title":"Exp Neurol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0115","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1007\/s00259-011-1960-4","article-title":"Amyloid-b imaging with PET inAlzheimer\u2019s disease: is it feasible with current radiotracers and technologies?","volume":"39","author":"Moghbel","year":"2012","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0116","doi-asserted-by":"crossref","first-page":"613","DOI":"10.3233\/JAD-130485","article-title":"Amyloid-b positron emis-sion tomography imaging probes: a critical review","volume":"36","author":"Kepe","year":"2013","journal-title":"J Alzheimers Dis"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0117","doi-asserted-by":"crossref","first-page":"e441","DOI":"10.1038\/tp.2014.91","article-title":"Tauopathy PET and amyloidPET in the diagnosis of chronic traumatic encephalopathies: studies of retired NFL players and of a man with FTD and a severe head injury","volume":"4","author":"Mitsis","year":"2014","journal-title":"Transl Psychiatry"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0118","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.neulet.2017.06.055","article-title":"Self-reported traumatic brain injury and in vivo measure of AD-vulnerable cortical thickness and AD-related biomarkers in the ADNI cohort","volume":"655","author":"Wang","year":"2017","journal-title":"Neurosci Lett"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0119","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/j.nicl.2018.05.016","article-title":"Department of Defense Alzheimer\u2019s Disease Neuroimaging Initiative amyloid pathology fingerprint differentiates post-traumatic stress disorder and traumatic brain injury","volume":"19","author":"Mohamed","year":"2018","journal-title":"Neuroimage Clin"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0120","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1212\/01.wnl.0000438229.56094.54","article-title":"Head trauma and in vivo measures of amyloid and neurodegeneration in a population-based study","volume":"82","author":"Mielke","year":"2014","journal-title":"Neurology"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0121","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1001\/jamaneurol.2013.4847","article-title":"Amyloid imaging with carbon 11-labeled Pittsburgh compound B for traumatic brain injury","volume":"71","author":"Hong","year":"2014","journal-title":"JAMA Neurol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0122","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1111\/psyg.12383","article-title":"Detection of brain amyloid-\u03b2 deposits due to the repetitive head trauma in a former karate player","volume":"19","author":"Takahashi","year":"2019","journal-title":"Psychogeriatrics"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0123","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.3109\/02699052.2013.794963","article-title":"Detection of brain amyloid \u03b2 deposition in patients with neuropsychological impairment after traumatic brain injury: PET evaluation using Pittsburgh Compound-B","volume":"27","author":"Kawai","year":"2013","journal-title":"Brain Inj"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0124","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1038\/s41380-018-0239-6","article-title":"Neurotransmitter changes after traumatic brain injury: an update for new treatment strategies","volume":"24","author":"McGuire","year":"2019","journal-title":"Mol Psychiatry"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0125","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/j.neuroimage.2008.12.005","article-title":"[18F] flumazenil binding to central benzodiazepine receptor studies by PET\u2013quantitative analysis and comparisons with [11C]flumazenil","volume":"45","author":"Odano","year":"2009","journal-title":"Neuroimage"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0126","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1089\/neu.2015.4051","article-title":"Neuropsychological, metabolic, and GABAA receptor studies in subjects with repetitive traumatic brain injury","volume":"33","author":"Bang","year":"2016","journal-title":"J Neurotrauma"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0127","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/0020-708X(84)90215-1","article-title":"Synthesis of ethyl 8-fluoro5,6-dihydro-5-[11C]methyl-6-oxo-4H-imidazo [1,5-a] [1,4]benzodiazepine-3- carboxylate (RO 15.1788-11C): a specific radioligand for the in vivo study of central benzodiazepine receptors by positron emission tomography","volume":"35","author":"Maziere","year":"1984","journal-title":"Int J Appl Radiat Isot"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0128","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1007\/s00259-005-0033-y","article-title":"Loss of neuronal integrity: a cause of hypometabolism in patients with traumatic brain injury without MRI abnormality in the chronic stage","volume":"33","author":"Shiga","year":"2006","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0129","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1089\/neu.2010.1464","article-title":"Focal neuronal damage in patients with neuropsychological impairment after diffuse traumatic brain injury: evaluation using 11C-flumazenil positron emission tomography with statistical image analysis","volume":"27","author":"Kawai","year":"2010","journal-title":"J Neurotrauma"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0130","first-page":"1","article-title":"Memory deficits due to brain injury: unique PET findings and dream alterations","volume":"1","author":"Nishida","year":"2011","journal-title":"BMJ Case Rep"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0131","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.biopsych.2010.04.038","article-title":"Imaging dopamine D3 receptors in the human brain with positron emission tomography, [11C]PHNO, and a selective D3 receptor antagonist","volume":"68","author":"Searle","year":"2010","journal-title":"Biol Psychiatr"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0132","article-title":"Dopamine D2\/D3 receptor abnormalities after traumatic brain injury and their relationship to post-traumatic depression","volume":"24","author":"Jolly","year":"2019","journal-title":"Neurolmage Clin"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0133","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/1742-2094-8-67","article-title":"Increased cerebral (R)-[(11)C] PK11195 uptake and glutamate release in a rat model of traumatic brain injury: a longitudinal pilot study","volume":"8","author":"Folkersma","year":"2011","journal-title":"J Neuroinflammation"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0134","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.nbd.2014.10.019","article-title":"Neuroinflammation and brain atrophy in former NFL players: an in vivo multimodal imaging pilot study","volume":"74","author":"Coughlin","year":"2015","journal-title":"Neurobiol Dis"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0135","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1186\/s12974-016-0604-9","article-title":"Combined [18F]DPA-714 micro-positron emission tomography and autoradiography imaging of microglia activation after closed head injury in mice","volume":"13","author":"Israel","year":"2016","journal-title":"J Neuroinflammation"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0136","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1001\/jamaneurol.2016.3764","article-title":"Imaging of glial cell activation and white matter integrity in brains of active and recently retired national football league players","volume":"74","author":"Coughlin","year":"2017","journal-title":"JAMA Neurol"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0137","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1038\/jcbfm.2012.46","article-title":"Translocator protein (18 kDa) polymorphism (rs6971) explains invivo brain binding affinity of the PET radioligand [(18)F]-FEPPA","volume":"32","author":"Mizrahi","year":"2012","journal-title":"J Cereb Blood Flow Metab Off J Int Soc Cereb Blood Flow Metab"},{"key":"10.1053\/j.semnuclmed.2025.06.002_bib0138","first-page":"320","article-title":"11C-ER176, a radioligand for 18-kDa translocator protein, has adequate sensitivity to robustly image all three affinity genotypes in the human brain","volume":"58","author":"Ikawa","year":"2017","journal-title":"J Nucl Med Off Publ Soc Nucl Med"}],"container-title":["Seminars in Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001299825000674?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001299825000674?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T17:08:53Z","timestamp":1751476133000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0001299825000674"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":138,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["S0001299825000674"],"URL":"https:\/\/doi.org\/10.1053\/j.semnuclmed.2025.06.002","relation":{},"ISSN":["0001-2998"],"issn-type":[{"value":"0001-2998","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neuroimaging of Mild Traumatic Injury","name":"articletitle","label":"Article Title"},{"value":"Seminars in Nuclear Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.semnuclmed.2025.06.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}