{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T18:45:40Z","timestamp":1768070740840,"version":"3.49.0"},"reference-count":78,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["semultrasoundctmri.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Ultrasound, CT and MRI"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1053\/j.sult.2016.10.002","type":"journal-article","created":{"date-parts":[[2016,10,17]],"date-time":"2016-10-17T17:54:22Z","timestamp":1476726862000},"page":"59-71","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Hereditary Renal Tumor Syndromes: Update on Diagnosis and Management"],"prefix":"10.1053","volume":"38","author":[{"given":"Sonia","family":"Gaur","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baris","family":"Turkbey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Choyke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6 Pt 1","key":"10.1053\/j.sult.2016.10.002_bib1","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1097\/01.ju.0000096060.92397.ed","article-title":"The genetic basis of cancer of the kidney","volume":"170","author":"Linehan","year":"2003","journal-title":"J Urol"},{"issue":"9-10","key":"10.1053\/j.sult.2016.10.002_bib2","doi-asserted-by":"crossref","first-page":"324","DOI":"10.5489\/cuaj.1685","article-title":"Evaluation and screening for hereditary renal cell cancers","volume":"7","author":"Linehan","year":"2013","journal-title":"Can Urol Assoc J"},{"issue":"12","key":"10.1053\/j.sult.2016.10.002_bib3","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1097\/PAS.0000000000000562","article-title":"Hereditary renal cell carcinoma syndromes: Clinical, pathologic, and genetic features","volume":"39","author":"Adeniran","year":"2015","journal-title":"Am J Surg Pathol"},{"issue":"4","key":"10.1053\/j.sult.2016.10.002_bib4","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1053\/j.seminoncol.2013.05.009","article-title":"Non-clear cell renal cancer: Disease-based management and opportunities for targeted therapeutic approaches","volume":"40","author":"Linehan","year":"2013","journal-title":"Semin Oncol"},{"issue":"1","key":"10.1053\/j.sult.2016.10.002_bib5","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.semcancer.2012.05.005","article-title":"Von Hippel-Lindau: How a rare disease illuminates cancer biology","volume":"23","author":"Richard","year":"2013","journal-title":"Semin Cancer Biol"},{"issue":"6","key":"10.1053\/j.sult.2016.10.002_bib6","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1007\/s00261-016-0743-6","article-title":"Inherited renal carcinomas","volume":"41","author":"Kawashima","year":"2016","journal-title":"Abdom Radiol (NY)"},{"issue":"5","key":"10.1053\/j.sult.2016.10.002_bib7","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1097\/MOU.0b013e32832f0d40","article-title":"Hereditary and familial kidney cancer","volume":"19","author":"Coleman","year":"2009","journal-title":"Curr Opin Urol"},{"issue":"3","key":"10.1053\/j.sult.2016.10.002_bib8","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1007\/s00345-014-1287-4","article-title":"Hereditary renal cell carcinoma: Genetics, clinical features, and surgical considerations","volume":"32","author":"Byler","year":"2014","journal-title":"World J Urol"},{"issue":"8","key":"10.1053\/j.sult.2016.10.002_bib9","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1007\/s11912-016-0537-6","article-title":"Therapeutic strategies for hereditary kidney cancer","volume":"18","author":"Sidana","year":"2016","journal-title":"Curr Oncol Rep"},{"issue":"10","key":"10.1053\/j.sult.2016.10.002_bib10","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.2169\/internalmedicine.51.7211","article-title":"Birt-Hogg-Dube syndrome with renal angiomyolipoma","volume":"51","author":"Tobino","year":"2012","journal-title":"Intern Med"},{"issue":"2","key":"10.1053\/j.sult.2016.10.002_bib11","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/j.1440-0960.2011.00738.x","article-title":"Birt-Hogg-Dube syndrome with a renal angiomyolipoma: Further evidence of a relationship between Birt-Hogg-Dube syndrome and tuberous sclerosis complex","volume":"53","author":"Byrne","year":"2012","journal-title":"Australas J Dermatol"},{"issue":"1","key":"10.1053\/j.sult.2016.10.002_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/jmg.39.1.1","article-title":"Familial adult renal neoplasia","volume":"39","author":"Takahashi","year":"2002","journal-title":"J Med Genet"},{"issue":"12","key":"10.1053\/j.sult.2016.10.002_bib13","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1136\/jmg.39.12.906","article-title":"Clinical and genetic studies of Birt-Hogg-Dube syndrome","volume":"39","author":"Khoo","year":"2002","journal-title":"J Med Genet"},{"issue":"10","key":"10.1053\/j.sult.2016.10.002_bib14","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1097\/PAS.0b013e318299f2d1","article-title":"The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia","volume":"37","author":"Srigley","year":"2013","journal-title":"Am J Surg Pathol"},{"issue":"12","key":"10.1053\/j.sult.2016.10.002_bib15","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.5858\/2006-130-1865-BSCFAG","article-title":"Birt-Hogg-Dube syndrome: Clinicopathologic findings and genetic alterations","volume":"130","author":"Adley","year":"2006","journal-title":"Arch Pathol Lab Med"},{"issue":"3","key":"10.1053\/j.sult.2016.10.002_bib16","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1038\/sj.jid.5700592","article-title":"Novel mutations in the BHD gene and absence of loss of heterozygosity in fibrofolliculomas of Birt-Hogg-Dube patients","volume":"127","author":"van Steensel","year":"2007","journal-title":"J Invest Dermatol"},{"issue":"4","key":"10.1053\/j.sult.2016.10.002_bib17","first-page":"393","article-title":"Risk of renal and colonic neoplasms and spontaneous pneumothorax in the Birt-Hogg-Dube syndrome","volume":"11","author":"Zbar","year":"2002","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"6","key":"10.1053\/j.sult.2016.10.002_bib18","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1136\/jmg.2007.054304","article-title":"BHD mutations, clinical and molecular genetic investigations of Birt-Hogg-Dube syndrome: A new series of 50 families and a review of published reports","volume":"45","author":"Toro","year":"2008","journal-title":"J Med Genet"},{"issue":"1","key":"10.1053\/j.sult.2016.10.002_bib19","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1148\/radiol.2261011296","article-title":"Hereditary renal cancers","volume":"226","author":"Choyke","year":"2003","journal-title":"Radiology"},{"issue":"12","key":"10.1053\/j.sult.2016.10.002_bib20","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1016\/S1470-2045(09)70188-3","article-title":"Birt-Hogg-Dube syndrome: Diagnosis and management","volume":"10","author":"Menko","year":"2009","journal-title":"Lancet Oncol"},{"issue":"9","key":"10.1053\/j.sult.2016.10.002_bib21","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.6004\/jnccn.2014.0129","article-title":"Genetic kidney cancer syndromes","volume":"12","author":"Ho","year":"2014","journal-title":"J Natl Compr Canc Netw"},{"issue":"11","key":"10.1053\/j.sult.2016.10.002_bib22","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1097\/PAS.0000000000000248","article-title":"Tuberous sclerosis-associated renal cell carcinoma: A clinicopathologic study of 57 separate carcinomas in 18 patients","volume":"38","author":"Guo","year":"2014","journal-title":"Am J Surg Pathol"},{"issue":"5327","key":"10.1053\/j.sult.2016.10.002_bib23","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1126\/science.277.5327.805","article-title":"Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34","volume":"277","author":"van Slegtenhorst","year":"1997","journal-title":"Science"},{"issue":"2","key":"10.1053\/j.sult.2016.10.002_bib24","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1097\/00000478-200202000-00006","article-title":"Renal disease in adults with TSC2\/PKD1 contiguous gene syndrome","volume":"26","author":"Martignoni","year":"2002","journal-title":"Am J Surg Pathol"},{"issue":"7","key":"10.1053\/j.sult.2016.10.002_bib25","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1097\/PAS.0000000000000237","article-title":"Renal cell carcinoma in tuberous sclerosis complex","volume":"38","author":"Yang","year":"2014","journal-title":"Am J Surg Pathol"},{"issue":"5","key":"10.1053\/j.sult.2016.10.002_bib26","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.eururo.2010.08.031","article-title":"Hereditary renal cancer syndromes: An update of a systematic review","volume":"58","author":"Verine","year":"2010","journal-title":"Eur Urol"},{"issue":"5","key":"10.1053\/j.sult.2016.10.002_bib27","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1111\/j.1365-2362.2010.02270.x","article-title":"Hereditary causes of kidney tumours","volume":"40","author":"Axwijk","year":"2010","journal-title":"Eur J Clin Invest"},{"issue":"10","key":"10.1053\/j.sult.2016.10.002_bib28","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1038\/sj.ki.5001853","article-title":"Renal manifestations of tuberous sclerosis complex: Incidence, prognosis, and predictive factors","volume":"70","author":"Rakowski","year":"2006","journal-title":"Kidney Int"},{"issue":"2","key":"10.1053\/j.sult.2016.10.002_bib29","doi-asserted-by":"crossref","first-page":"W178","DOI":"10.2214\/AJR.12.8776","article-title":"Renal epithelioid angiomyolipoma: Imaging characteristics in nine cases with radiologic-pathologic correlation and review of the literature","volume":"200","author":"Froemming","year":"2013","journal-title":"AJR Am J Roentgenol"},{"issue":"11","key":"10.1053\/j.sult.2016.10.002_bib30","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1111\/iju.12117","article-title":"Epithelioid angiomyolipoma of the kidney: Radiological imaging","volume":"20","author":"Tsukada","year":"2013","journal-title":"Int J Urol"},{"issue":"9639","key":"10.1053\/j.sult.2016.10.002_bib31","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/S0140-6736(08)61279-9","article-title":"Tuberous sclerosis","volume":"372","author":"Curatolo","year":"2008","journal-title":"Lancet"},{"issue":"4","key":"10.1053\/j.sult.2016.10.002_bib32","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/0090-4295(91)80261-5","article-title":"Malignant renal tumors in tuberous sclerosis","volume":"37","author":"Washecka","year":"1991","journal-title":"Urology"},{"issue":"4","key":"10.1053\/j.sult.2016.10.002_bib33","first-page":"1201","article-title":"Tuberous sclerosis-associated renal cell carcinoma. Clinical, pathological, and genetic features","volume":"149","author":"Bjornsson","year":"1996","journal-title":"Am J Pathol"},{"issue":"1","key":"10.1053\/j.sult.2016.10.002_bib34","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1148\/radiol.12111205","article-title":"Small (<4cm) renal mass: Differentiation of angiomyolipoma without visible fat from renal cell carcinoma utilizing MR imaging","volume":"263","author":"Sasiwimonphan","year":"2012","journal-title":"Radiology"},{"issue":"2","key":"10.1053\/j.sult.2016.10.002_bib35","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1148\/radiology.205.2.9356635","article-title":"Angiomyolipoma: Imaging findings in lesions with minimal fat","volume":"205","author":"Jinzaki","year":"1997","journal-title":"Radiology"},{"issue":"4","key":"10.1053\/j.sult.2016.10.002_bib36","first-page":"437","article-title":"Genetic alterations and histopathologic findings in familial renal cell carcinoma","volume":"21","author":"Hansel","year":"2006","journal-title":"Histol Histopathol"},{"issue":"13","key":"10.1053\/j.sult.2016.10.002_bib37","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1056\/NEJMra055323","article-title":"The tuberous sclerosis complex","volume":"355","author":"Crino","year":"2006","journal-title":"N Engl J Med"},{"issue":"5","key":"10.1053\/j.sult.2016.10.002_bib38","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.2214\/AJR.14.13514","article-title":"Diagnostic approach to hereditary renal cell carcinoma","volume":"204","author":"Gupta","year":"2015","journal-title":"AJR Am J Roentgenol"},{"issue":"12","key":"10.1053\/j.sult.2016.10.002_bib39","doi-asserted-by":"crossref","first-page":"4071","DOI":"10.1158\/1078-0432.CCR-11-0445","article-title":"Sirolimus therapy for angiomyolipoma in tuberous sclerosis and sporadic lymphangioleiomyomatosis: A phase 2 trial","volume":"17","author":"Davies","year":"2011","journal-title":"Clin Cancer Res"},{"issue":"9","key":"10.1053\/j.sult.2016.10.002_bib40","doi-asserted-by":"crossref","first-page":"e23379","DOI":"10.1371\/journal.pone.0023379","article-title":"Multicenter phase 2 trial of sirolimus for tuberous sclerosis: Kidney angiomyolipomas and other tumors regress and VEGF-D levels decrease","volume":"6","author":"Dabora","year":"2011","journal-title":"PLoS One"},{"issue":"9869","key":"10.1053\/j.sult.2016.10.002_bib41","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/S0140-6736(12)61767-X","article-title":"Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis (EXIST-2): A multicentre, randomised, double-blind, placebo-controlled trial","volume":"381","author":"Bissler","year":"2013","journal-title":"Lancet"},{"issue":"6","key":"10.1053\/j.sult.2016.10.002_bib42","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1093\/ndt\/gfu013","article-title":"The effect of everolimus on renal angiomyolipoma in patients with tuberous sclerosis complex being treated for subependymal giant cell astrocytoma: Subgroup results from the randomized, placebo-controlled, Phase 3 trial EXIST-1","volume":"29","author":"Kingswood","year":"2014","journal-title":"Nephrol Dial Transplant"},{"issue":"3","key":"10.1053\/j.sult.2016.10.002_bib43","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/S0022-5347(17)35015-2","article-title":"Hereditary papillary renal cell carcinoma","volume":"151","author":"Zbar","year":"1994","journal-title":"J Urol"},{"issue":"1","key":"10.1053\/j.sult.2016.10.002_bib44","doi-asserted-by":"crossref","first-page":"e21","DOI":"10.1159\/000320892","article-title":"Genetics of familial renal cancers","volume":"118","author":"Maher","year":"2011","journal-title":"Nephron Exp Nephrol"},{"issue":"12","key":"10.1053\/j.sult.2016.10.002_bib45","doi-asserted-by":"crossref","first-page":"3657","DOI":"10.1158\/1078-0432.CCR-06-0818","article-title":"Targeting the c-Met signaling pathway in cancer","volume":"12","author":"Peruzzi","year":"2006","journal-title":"Clin Cancer Res"},{"issue":"1","key":"10.1053\/j.sult.2016.10.002_bib46","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/nrc3844","article-title":"VHL, the story of a tumour suppressor gene","volume":"15","author":"Gossage","year":"2015","journal-title":"Nat Rev Cancer"},{"issue":"2","key":"10.1053\/j.sult.2016.10.002_bib47","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1056\/NEJMoa1505917","article-title":"Comprehensive molecular characterization of papillary renal-cell carcinoma","volume":"374","author":"Cancer Genome Atlas Research Network","year":"2016","journal-title":"N Engl J Med"},{"issue":"2","key":"10.1053\/j.sult.2016.10.002_bib48","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/S0022-5347(05)67893-7","article-title":"Prevalence of microscopic tumors in normal appearing renal parenchyma of patients with hereditary papillary renal cancer","volume":"163","author":"Ornstein","year":"2000","journal-title":"J Urol"},{"issue":"2","key":"10.1053\/j.sult.2016.10.002_bib49","doi-asserted-by":"crossref","first-page":"347","DOI":"10.2214\/AJR.12.9451","article-title":"Differentiation of papillary renal cell carcinoma subtypes on CT and MRI","volume":"201","author":"Egbert","year":"2013","journal-title":"AJR Am J Roentgenol"},{"issue":"15","key":"10.1053\/j.sult.2016.10.002_bib50","doi-asserted-by":"crossref","first-page":"4080","DOI":"10.1128\/MCB.00483-09","article-title":"Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1alpha stabilization by glucose-dependent generation of reactive oxygen species","volume":"29","author":"Sudarshan","year":"2009","journal-title":"Mol Cell Biol"},{"issue":"6","key":"10.1053\/j.sult.2016.10.002_bib51","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1586\/era.13.57","article-title":"Aerobic glycolysis: A novel target in kidney cancer","volume":"13","author":"Shuch","year":"2013","journal-title":"Expert Rev Anticancer Ther"},{"issue":"4","key":"10.1053\/j.sult.2016.10.002_bib52","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1136\/jmg.2010.085068","article-title":"Novel FH mutations in families with hereditary leiomyomatosis and renal cell cancer (HLRCC) and patients with isolated type 2 papillary renal cell carcinoma","volume":"48","author":"Gardie","year":"2011","journal-title":"J Med Genet"},{"key":"10.1053\/j.sult.2016.10.002_bib53","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1471-2490-13-3","article-title":"Hereditary papillary renal cell carcinoma primarily diagnosed in a cervical lymph node: A case report of a 30-year-old woman with multiple metastases","volume":"13","author":"Behnes","year":"2013","journal-title":"BMC Urol"},{"issue":"1","key":"10.1053\/j.sult.2016.10.002_bib54","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s11934-010-0156-y","article-title":"Impact of genetics on the diagnosis and treatment of renal cancer","volume":"12","author":"Singer","year":"2011","journal-title":"Curr Urol Rep"},{"issue":"10","key":"10.1053\/j.sult.2016.10.002_bib55","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1097\/PAS.0b013e31804375b8","article-title":"The morphologic spectrum of kidney tumors in hereditary leiomyomatosis and renal cell carcinoma (HLRCC) syndrome","volume":"31","author":"Merino","year":"2007","journal-title":"Am J Surg Pathol"},{"issue":"6","key":"10.1053\/j.sult.2016.10.002_bib56","doi-asserted-by":"crossref","first-page":"2074","DOI":"10.1016\/j.juro.2007.01.155","article-title":"Hereditary leiomyomatosis and renal cell cancer: A syndrome associated with an aggressive form of inherited renal cancer","volume":"177","author":"Grubb","year":"2007","journal-title":"J Urol"},{"issue":"11","key":"10.1053\/j.sult.2016.10.002_bib57","doi-asserted-by":"crossref","first-page":"2089","DOI":"10.1101\/gr.131110.111","article-title":"Genetic basis of kidney cancer: Role of genomics for the development of disease-based therapeutics","volume":"22","author":"Linehan","year":"2012","journal-title":"Genome Res"},{"issue":"5","key":"10.1053\/j.sult.2016.10.002_bib58","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1097\/01.ju.0000154629.45832.30","article-title":"Evaluation and management of renal tumors in the Birt-Hogg-Dube syndrome","volume":"173","author":"Pavlovich","year":"2005","journal-title":"J Urol"},{"issue":"5","key":"10.1053\/j.sult.2016.10.002_bib59","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1016\/S0022-5347(05)68930-6","article-title":"Renal cancer in families with hereditary renal cancer: Prospective analysis of a tumor size threshold for renal parenchymal sparing surgery","volume":"161","author":"Walther","year":"1999","journal-title":"J Urol"},{"issue":"4","key":"10.1053\/j.sult.2016.10.002_bib60","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1053\/j.sult.2009.03.003","article-title":"Renal cell carcinoma: Recent advances in genetics and imaging","volume":"30","author":"Choudhary","year":"2009","journal-title":"Semin Ultrasound CT MR"},{"issue":"4","key":"10.1053\/j.sult.2016.10.002_bib61","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1097\/PAP.0b013e318299b7c6","article-title":"Hereditary syndromes with associated renal neoplasia: A practical guide to histologic recognition in renal tumor resection specimens","volume":"20","author":"Przybycin","year":"2013","journal-title":"Adv Anat Pathol"},{"issue":"12","key":"10.1053\/j.sult.2016.10.002_bib62","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1016\/j.humpath.2011.02.026","article-title":"Renal medullary carcinomas: Histopathologic phenotype associated with diverse genotypes","volume":"42","author":"Gatalica","year":"2011","journal-title":"Hum Pathol"},{"issue":"6733","key":"10.1053\/j.sult.2016.10.002_bib63","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/20459","article-title":"The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis","volume":"399","author":"Maxwell","year":"1999","journal-title":"Nature"},{"issue":"1","key":"10.1053\/j.sult.2016.10.002_bib64","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.juro.2015.02.081","article-title":"Lynch syndrome: A primer for urologists and panel recommendations","volume":"194","author":"Mork","year":"2015","journal-title":"J Urol"},{"issue":"26","key":"10.1053\/j.sult.2016.10.002_bib65","doi-asserted-by":"crossref","first-page":"4285","DOI":"10.1200\/JCO.2005.03.7333","article-title":"Genotype-phenotype comparison of German MLH1 and MSH2 mutation carriers clinically affected with Lynch syndrome: A report by the German HNPCC Consortium","volume":"24","author":"Goecke","year":"2006","journal-title":"J Clin Oncol"},{"issue":"5","key":"10.1053\/j.sult.2016.10.002_bib66","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1016\/j.juro.2010.12.102","article-title":"Upper urinary tract carcinoma in Lynch syndrome cases","volume":"185","author":"Crockett","year":"2011","journal-title":"J Urol"},{"issue":"suppl 1","key":"10.1053\/j.sult.2016.10.002_bib67","doi-asserted-by":"crossref","first-page":"S35","DOI":"10.1148\/rg.24si045513","article-title":"CT urography","volume":"24","author":"Kawashima","year":"2004","journal-title":"Radiographics"},{"issue":"6","key":"10.1053\/j.sult.2016.10.002_bib68","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.2214\/AJR.09.2577","article-title":"Imaging and staging of transitional cell carcinoma: Part 2, upper urinary tract","volume":"192","author":"Vikram","year":"2009","journal-title":"AJR Am J Roentgenol"},{"issue":"6","key":"10.1053\/j.sult.2016.10.002_bib69","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.2214\/AJR.13.10673","article-title":"Utility of MRI features in differentiation of central renal cell carcinoma and renal pelvic urothelial carcinoma","volume":"201","author":"Wehrli","year":"2013","journal-title":"AJR Am J Roentgenol"},{"issue":"6","key":"10.1053\/j.sult.2016.10.002_bib70","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1016\/j.eururo.2008.08.008","article-title":"Upper urinary tract urothelial cell carcinomas and other urological malignancies involved in the hereditary nonpolyposis colorectal cancer (Lynch syndrome) tumor spectrum","volume":"54","author":"Roupret","year":"2008","journal-title":"Eur Urol"},{"issue":"12","key":"10.1053\/j.sult.2016.10.002_bib71","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1097\/PAS.0000000000000292","article-title":"Succinate dehydrogenase (SDH)-deficient renal carcinoma: A morphologically distinct entity: A clinicopathologic series of 36 tumors from 27 patients","volume":"38","author":"Gill","year":"2014","journal-title":"Am J Surg Pathol"},{"issue":"1","key":"10.1053\/j.sult.2016.10.002_bib72","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1002\/humu.21136","article-title":"Tumor risks and genotype-phenotype-proteotype analysis in 358 patients with germline mutations in SDHB and SDHD","volume":"31","author":"Ricketts","year":"2010","journal-title":"Hum Mutat"},{"issue":"17","key":"10.1053\/j.sult.2016.10.002_bib73","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1093\/jnci\/djn254","article-title":"Germline SDHB mutations and familial renal cell carcinoma","volume":"100","author":"Ricketts","year":"2008","journal-title":"J Natl Cancer Inst"},{"issue":"1","key":"10.1053\/j.sult.2016.10.002_bib74","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/modpathol.2014.86","article-title":"Succinate dehydrogenase-deficient renal cell carcinoma: Detailed characterization of 11 tumors defining a unique subtype of renal cell carcinoma","volume":"28","author":"Williamson","year":"2015","journal-title":"Mod Pathol"},{"issue":"13","key":"10.1053\/j.sult.2016.10.002_bib75","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1093\/jnci\/91.13.1159","article-title":"Renal cell cancer: Chromosome 3 translocations as risk factors","volume":"91","author":"van Kessel","year":"1999","journal-title":"J Natl Cancer Inst"},{"issue":"1","key":"10.1053\/j.sult.2016.10.002_bib76","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1038\/ng0596-114","article-title":"Localization of the gene for Cowden disease to chromosome 10q22-23","volume":"13","author":"Nelen","year":"1996","journal-title":"Nat Genet"},{"issue":"5","key":"10.1053\/j.sult.2016.10.002_bib77","doi-asserted-by":"crossref","DOI":"10.1016\/j.urology.2011.12.025","article-title":"Papillary renal cell carcinoma is associated with PTEN hamartoma tumor syndrome","volume":"79","author":"Mester","year":"2012","journal-title":"Urology"},{"issue":"2","key":"10.1053\/j.sult.2016.10.002_bib78","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1158\/1078-0432.CCR-11-2283","article-title":"Lifetime cancer risks in individuals with germline PTEN mutations","volume":"18","author":"Tan","year":"2012","journal-title":"Clin Cancer Res"}],"container-title":["Seminars in Ultrasound, CT and MRI"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S088721711630083X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S088721711630083X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,10]],"date-time":"2022-07-10T15:08:05Z","timestamp":1657465685000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S088721711630083X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":78,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["S088721711630083X"],"URL":"https:\/\/doi.org\/10.1053\/j.sult.2016.10.002","relation":{},"ISSN":["0887-2171"],"issn-type":[{"value":"0887-2171","type":"print"}],"subject":[],"published":{"date-parts":[[2017,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hereditary Renal Tumor Syndromes: Update on Diagnosis and Management","name":"articletitle","label":"Article Title"},{"value":"Seminars in Ultrasound, CT and MRI","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.sult.2016.10.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}