{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T01:29:08Z","timestamp":1791595748934,"version":"4.3.4"},"reference-count":43,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Ultrasound, CT and MRI"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1053\/j.sult.2022.10.005","type":"journal-article","created":{"date-parts":[[2022,10,29]],"date-time":"2022-10-29T19:57:11Z","timestamp":1667073431000},"page":"46-55","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["High-Risk Lesion Management"],"prefix":"10.1053","volume":"44","author":[{"given":"Joao V.","family":"Horvat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/j.sult.2022.10.005_bib0001","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/s10549-018-05071-1","article-title":"Second international consensus conference on lesions of uncertain malignant potential in the breast (B3 lesions)","volume":"174","author":"Rageth","year":"2019","journal-title":"Breast Cancer Res Treat"},{"key":"10.1053\/j.sult.2022.10.005_bib0002","doi-asserted-by":"crossref","unstructured":"Harbhajanka A, Gilmore HL, Calhoun BC: High-risk and selected benign breast lesions diagnosed on core needle biopsy: Evidence for and against immediate surgical excision. Mod Pathol 2022. https:\/\/doi.org\/10.1038\/s41379-022-01092-w","DOI":"10.1038\/s41379-022-01092-w"},{"key":"10.1053\/j.sult.2022.10.005_bib0003","doi-asserted-by":"crossref","first-page":"691","DOI":"10.6004\/jnccn.2022.0030","article-title":"Breast Cancer, Version 3.2022, NCCN clinical practice guidelines in oncology","volume":"20","author":"Gradishar","year":"2022","journal-title":"J Natl Compr Canc Netw"},{"key":"10.1053\/j.sult.2022.10.005_bib0004","doi-asserted-by":"crossref","unstructured":"Catanzariti F, Avendano D, Cicero G, et al: High-risk lesions of the breast: concurrent diagnostic tools and management recommendations. Insights Imaging 12:63, 2021. https:\/\/doi.org\/10.1186\/s13244-021-01005-6","DOI":"10.1186\/s13244-021-01005-6"},{"key":"10.1053\/j.sult.2022.10.005_bib0005","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.amjsurg.2006.06.003","article-title":"Correlation between core biopsy and excisional biopsy in breast high-risk lesions","volume":"192","author":"Margenthaler","year":"2006","journal-title":"Am J Surg"},{"key":"10.1053\/j.sult.2022.10.005_bib0006","doi-asserted-by":"crossref","first-page":"705","DOI":"10.3892\/mco.2016.790","article-title":"B3-lesions of the breast and cancer risk - an analysis of mammography screening patients","volume":"4","author":"Hoffmann","year":"2016","journal-title":"Mol Clin Oncol"},{"key":"10.1053\/j.sult.2022.10.005_bib0007","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.ejso.2018.12.008","article-title":"High risk (B3) breast lesions: What is the incidence of malignancy for individual lesion subtypes? A systematic review and meta-analysis","volume":"45","author":"Forester","year":"2019","journal-title":"Eur J Surg Oncol"},{"key":"10.1053\/j.sult.2022.10.005_bib0008","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1111\/tbj.14117","article-title":"Lobular intraepithelial neoplasia: Outcomes and optimal management","volume":"26","author":"Boland","year":"2020","journal-title":"Breast J"},{"key":"10.1053\/j.sult.2022.10.005_bib0009","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.rcl.2020.08.005","article-title":"Management of high-risk breast lesions","volume":"59","author":"Bahl","year":"2021","journal-title":"Radiol Clin North Am"},{"key":"10.1053\/j.sult.2022.10.005_bib0010","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1007\/s00330-010-1949-6","article-title":"High-risk lesions diagnosed at MRI-guided vacuum-assisted breast biopsy: Can underestimation be predicted?","volume":"21","author":"Crystal","year":"2011","journal-title":"Eur Radiol"},{"key":"10.1053\/j.sult.2022.10.005_bib0011","doi-asserted-by":"crossref","first-page":"682","DOI":"10.2214\/AJR.13.11905","article-title":"High-risk lesions at MRI-guided breast biopsy: Frequency and rate of underestimation","volume":"203","author":"Lourenco","year":"2014","journal-title":"AJR Am J Roentgenol"},{"key":"10.1053\/j.sult.2022.10.005_bib0012","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.breast.2017.07.009","article-title":"Reduction mammaplasty in patients with history of breast cancer: The incidence of occult cancer and high-risk lesions","volume":"35","author":"Merkkola-von Schantz","year":"2017","journal-title":"Breast"},{"key":"10.1053\/j.sult.2022.10.005_bib0013","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1097\/SAP.0000000000001482","article-title":"A risk-stratified comparison of high-risk findings in reduction mammoplasty","volume":"81","author":"Dreifuss","year":"2018","journal-title":"Ann Plast Surg"},{"key":"10.1053\/j.sult.2022.10.005_bib0014","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1016\/j.ejso.2022.04.005","article-title":"The positive predictive value of vacuum assisted biopsy (VAB) in predicting final histological diagnosis for breast lesions of uncertain malignancy (B3 lesions): A systematic review & meta-analysis","volume":"48","author":"Cullinane","year":"2022","journal-title":"Eur J Surg Oncol"},{"key":"10.1053\/j.sult.2022.10.005_bib0015","doi-asserted-by":"crossref","first-page":"4622","DOI":"10.1245\/s10434-020-08881-0","article-title":"Development and prospective validation of a risk calculator that predicts a low risk cohort for atypical ductal hyperplasia upstaging to malignancy: Evidence for a watch and wait strategy of a high-risk lesion","volume":"27","author":"Lustig","year":"2020","journal-title":"Ann Surg Oncol"},{"key":"10.1053\/j.sult.2022.10.005_bib0016","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1007\/s10549-012-2318-8","article-title":"The role of chemoprevention in modifying the risk of breast cancer in women with atypical breast lesions","volume":"136","author":"Coopey","year":"2012","journal-title":"Breast Cancer Res Treat"},{"key":"10.1053\/j.sult.2022.10.005_bib0017","doi-asserted-by":"crossref","first-page":"3614","DOI":"10.1245\/s10434-020-08476-9","article-title":"Factors predicting breast cancer development in women during surveillance after surgery for atypical ductal hyperplasia of the breast: Analysis of clinical, radiologic, and histopathologic features","volume":"27","author":"Yoon","year":"2020","journal-title":"Ann Surg Oncol"},{"key":"10.1053\/j.sult.2022.10.005_bib0018","doi-asserted-by":"crossref","first-page":"3268","DOI":"10.1245\/s10434-014-3912-2","article-title":"Localizing high-risk lesions for excisional breast biopsy: A comparison between radioactive seed localization and wire localization","volume":"21","author":"Diego","year":"2014","journal-title":"Ann Surg Oncol"},{"key":"10.1053\/j.sult.2022.10.005_bib0019","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1148\/radiol.2017161661","article-title":"Beyond wires and seeds: Reflector-guided breast lesion localization and excision","volume":"284","author":"Mango","year":"2017","journal-title":"Radiology"},{"key":"10.1053\/j.sult.2022.10.005_bib0020","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/j.ejso.2014.02.222","article-title":"Phyllodes tumours of the breast diagnosed as B3 category on image-guided 14-gauge core biopsy: analysis of 51 cases from a single institution and review of the literature","volume":"40","author":"Abdulcadir","year":"2014","journal-title":"Eur J Surg Oncol"},{"key":"10.1053\/j.sult.2022.10.005_bib0021","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1186\/s12893-020-00869-7","article-title":"Breast papillary lesions diagnosed and treated using ultrasound-guided vacuum-assisted excision","volume":"20","author":"Li","year":"2020","journal-title":"BMC Surg"},{"key":"10.1053\/j.sult.2022.10.005_bib0022","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1148\/radiol.2019190096","article-title":"Benign breast papilloma without atypia: Outcomes of surgical excision versus US-guided directional vacuum-assisted removal or us follow-up","volume":"293","author":"Choi","year":"2019","journal-title":"Radiology"},{"key":"10.1053\/j.sult.2022.10.005_bib0023","doi-asserted-by":"crossref","first-page":"4069","DOI":"10.1007\/s00330-020-06701-3","article-title":"Atypical ductal hyperplasia: breast DCE-MRI can be used to reduce unnecessary open surgical excision","volume":"30","author":"Bertani","year":"2020","journal-title":"Eur Radiol"},{"key":"10.1053\/j.sult.2022.10.005_bib0024","doi-asserted-by":"crossref","first-page":"272","DOI":"10.2214\/AJR.11.7040","article-title":"Nonsurgical management of high-risk lesions diagnosed at core needle biopsy: Can malignancy be ruled out safely with breast MRI?","volume":"198","author":"Linda","year":"2012","journal-title":"AJR Am J Roentgenol"},{"key":"10.1053\/j.sult.2022.10.005_bib0025","doi-asserted-by":"crossref","first-page":"4786","DOI":"10.1245\/s10434-020-08896-7","article-title":"Ipsilateral and Concurrent Breast Cancer and Atypical Ductal Hyperplasia: Does Atypia also need surgical excision?","volume":"27","author":"Amin","year":"2020","journal-title":"Ann Surg Oncol"},{"key":"10.1053\/j.sult.2022.10.005_bib0026","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1097\/GRF.0000000000000234","article-title":"Pathologic high-risk lesions, diagnosis and management","volume":"59","author":"Murray","year":"2016","journal-title":"Clin Obstet Gynecol"},{"key":"10.1053\/j.sult.2022.10.005_bib0027","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1007\/s10549-020-05977-9","article-title":"Management of high-risk breast lesions diagnosed on core biopsies and experiences from prospective high-risk breast lesion conferences at an academic institution","volume":"185","author":"Li","year":"2021","journal-title":"Breast Cancer Res Treat"},{"key":"10.1053\/j.sult.2022.10.005_bib0028","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1007\/s10549-020-05890-1","article-title":"Atypical ductal hyperplasia bordering on DCIS on core biopsy is associated with higher risk of upgrade than conventional atypical ductal hyperplasia","volume":"184","author":"Pawloski","year":"2020","journal-title":"Breast Cancer Res Treat"},{"key":"10.1053\/j.sult.2022.10.005_bib0029","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejrad.2021.109826","article-title":"Clinical management of atypical ductal hyperplasia on vacuum-assisted biopsy of microcalcifications: External validation study of a decision tree selecting patients eligible for surveillance","volume":"141","author":"El Sanharawi","year":"2021","journal-title":"Eur J Radiol"},{"key":"10.1053\/j.sult.2022.10.005_bib0030","doi-asserted-by":"crossref","first-page":"622","DOI":"10.2214\/AJR.20.23040","article-title":"High-risk lesions detected by MRI-guided core Biopsy: Upgrade rates at surgical excision and implications for management","volume":"216","author":"Michaels","year":"2021","journal-title":"AJR Am J Roentgenol"},{"key":"10.1053\/j.sult.2022.10.005_bib0031","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s10549-019-05481-9","article-title":"Flat epithelial atypia: Are we being too aggressive?","volume":"179","author":"DiPasquale","year":"2020","journal-title":"Breast Cancer Res Treat"},{"key":"10.1053\/j.sult.2022.10.005_bib0032","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1016\/j.acra.2021.09.009","article-title":"Upgrade rates of pure, radiology-pathology concordant lobular neoplasia diagnosed on breast core needle Biopsy: Is surgical excision warranted?","volume":"29","author":"Karimi","year":"2022","journal-title":"Acad Radiol"},{"key":"10.1053\/j.sult.2022.10.005_bib0033","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.2214\/AJR.19.22599","article-title":"Management of lobular neoplasia found on core needle biopsy performed for calcifications using precise radiologic-pathologic correlation","volume":"216","author":"Kunjummen","year":"2021","journal-title":"AJR Am J Roentgenol"},{"key":"10.1053\/j.sult.2022.10.005_bib0034","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1245\/s10434-021-10827-z","article-title":"Atypical lobular hyperplasia and classic lobular carcinoma in situ can be safely managed without surgical excision","volume":"29","author":"Laws","year":"2022","journal-title":"Ann Surg Oncol"},{"key":"10.1053\/j.sult.2022.10.005_bib0035","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1159\/000516609","article-title":"Factors indicating surgical excision in classical type of lobular neoplasia of the breast","volume":"17","author":"Elfgen","year":"2022","journal-title":"Breast Care (Basel)"},{"key":"10.1053\/j.sult.2022.10.005_bib0036","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1245\/s10434-021-10828-y","article-title":"Comparison of outcomes for classic-type lobular carcinoma in situ managed with surgical excision after core biopsy versus observation","volume":"29","author":"Matar","year":"2022","journal-title":"Ann Surg Oncol"},{"key":"10.1053\/j.sult.2022.10.005_bib0037","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1038\/s41379-021-00796-9","article-title":"Morphologic subtypes of lobular carcinoma in situ diagnosed on core needle biopsy: Clinicopathologic features and findings at follow-up excision","volume":"34","author":"Kuba","year":"2021","journal-title":"Mod Pathol"},{"key":"10.1053\/j.sult.2022.10.005_bib0038","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s10549-018-4973-x","article-title":"Rate of radial scars by core biopsy and upgrading to malignancy or high-risk lesions before and after introduction of digital breast tomosynthesis","volume":"173","author":"Phantana-Angkool","year":"2019","journal-title":"Breast Cancer Res Treat"},{"key":"10.1053\/j.sult.2022.10.005_bib0039","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1038\/s41379-021-00996-3","article-title":"Breast lesions associated with mammographic architectural distortion: A study of 588 core needle biopsies","volume":"35","author":"Bachert","year":"2022","journal-title":"Mod Pathol"},{"key":"10.1053\/j.sult.2022.10.005_bib0040","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1186\/s12957-018-1537-9","article-title":"Magnetic resonance imaging features for differentiating breast papilloma with high-risk or malignant lesions from benign papilloma: A retrospective study on 158 patients","volume":"16","author":"Wang","year":"2018","journal-title":"World J Surg Oncol"},{"key":"10.1053\/j.sult.2022.10.005_bib0041","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1016\/j.crad.2008.02.012","article-title":"Radiological appearances of papillary breast lesions","volume":"63","author":"Brookes","year":"2008","journal-title":"Clin Radiol"},{"key":"10.1053\/j.sult.2022.10.005_bib0042","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/s10549-022-06631-2","article-title":"Excision of breast fibroepithelial lesions: When is it still necessary?-A 10-year review of a regional centre","volume":"194","author":"Mousa-Doust","year":"2022","journal-title":"Breast Cancer Res Treat"},{"key":"10.1053\/j.sult.2022.10.005_bib0043","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1245\/s10434-021-10931-0","article-title":"Upstaging of fibroepithelial lesions: A single-institution experience","volume":"29","author":"Mohan","year":"2022","journal-title":"Ann Surg Oncol"}],"container-title":["Seminars in Ultrasound, CT and MRI"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0887217122000798?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0887217122000798?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T22:26:51Z","timestamp":1760135211000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0887217122000798"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["S0887217122000798"],"URL":"https:\/\/doi.org\/10.1053\/j.sult.2022.10.005","relation":{},"ISSN":["0887-2171"],"issn-type":[{"value":"0887-2171","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"High-Risk Lesion Management","name":"articletitle","label":"Article Title"},{"value":"Seminars in Ultrasound, CT and MRI","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.sult.2022.10.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}