{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T04:40:20Z","timestamp":1769748020435,"version":"3.49.0"},"reference-count":20,"publisher":"Elsevier BV","issue":"2-3","license":[{"start":{"date-parts":[[2000,8,1]],"date-time":"2000-08-01T00:00:00Z","timestamp":965088000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Comparative Pathology"],"published-print":{"date-parts":[[2000,8]]},"DOI":"10.1053\/jcpa.2000.0406","type":"journal-article","created":{"date-parts":[[2002,9,19]],"date-time":"2002-09-19T13:56:27Z","timestamp":1032443787000},"page":"152-163","source":"Crossref","is-referenced-by-count":24,"title":["A Comparative Study of Pseudorabies Virus (PRV) Strains with Defects in Thymidine Kinase and Glycoprotein Genes"],"prefix":"10.1053","volume":"123","author":[{"given":"M.","family":"Ferrari","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.C.","family":"Mettenleiter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.G.","family":"Romanelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Cabassi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Corradi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Dal Mas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Silini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1053\/jcpa.2000.0406_RF1","doi-asserted-by":"crossref","first-page":"49","DOI":"10.3109\/13550289709015792","article-title":"Differential tropism of pseudorabies virus for sensory neurons in the cat","volume":"3","author":"Card","year":"1997","journal-title":"Journal of Neurovirology"},{"key":"10.1053\/jcpa.2000.0406_RF2","doi-asserted-by":"crossref","first-page":"3032","DOI":"10.1128\/JVI.66.5.3032-3041.1992","article-title":"Pseudorabies virus envelope glycoprotein gI influences both neurotropism and virulence during infection of the rat visual system","volume":"66","author":"Card","year":"1992","journal-title":"Journal of Virology"},{"key":"10.1053\/jcpa.2000.0406_RF3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1439-0450.1995.tb00675.x","article-title":"A study of two mutant strains of pseudorabies virus (PRV) unable to express thymidine kinase (TK) function","volume":"42","author":"Ferrari","year":"1995","journal-title":"Journal of Veterinary Medicine B"},{"key":"10.1053\/jcpa.2000.0406_RF4","first-page":"1","article-title":"The response of pigs inoculated with a thymidine kinase-negative (TK) pseudorabies virus to challenge infection with virulent virus","volume":"4","author":"Ferrari","year":"1999","journal-title":"Comparative Immunology, Microbiology and Infectious Diseases"},{"key":"10.1053\/jcpa.2000.0406_RF5","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/S0147-9571(98)00012-5","article-title":"Experimental infection of pigs with a thymidine kinase negative strain of pseudorabies virus","volume":"21","author":"Ferrari","year":"1998","journal-title":"Comparative Immunology, Microbiology and Infectious Diseases"},{"key":"10.1053\/jcpa.2000.0406_RF6","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/BF01309470","article-title":"Glycoprotein E of pseudorabies virus and homologous proteins in other Alphaherpesvirinae","volume":"137","author":"Jacobs","year":"1994","journal-title":"Archives of Virology"},{"key":"10.1053\/jcpa.2000.0406_RF7","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1099\/0022-1317-73-2-243","article-title":"Contribution of single genes within the unique short region of Aujeszky's disease virus (suid herpesvirus type 1) to virulence, pathogenesis and immunogenicity","volume":"73","author":"Kimman","year":"1992","journal-title":"Journal of General Virology"},{"key":"10.1053\/jcpa.2000.0406_RF8","first-page":"1359","article-title":"Attenuated properties of thymidine-kinase negative deletion mutant of pseudorabies virus","volume":"46","author":"Kit","year":"1985","journal-title":"American Journal of Veterinary Research"},{"key":"10.1053\/jcpa.2000.0406_RF9","first-page":"312","article-title":"Pseudorabies","author":"Kluge","year":"1992","journal-title":"In Diseases of Swine, 7th Edit, A. D. Leman, B. Straw, R. D. Glock, W. L. Mengeling, S. D\u00bbAllaire and D. J. Taylor, Eds, Iowa State University Press, Ames"},{"key":"10.1053\/jcpa.2000.0406_RF10","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/0378-1135(94)90120-1","article-title":"Invasion and spread of single glycoprotein-deleted mutants of Aujeszky's disease virus (ADV) in the trigeminal nervous pathway of pigs after intranasal inoculation","volume":"40","author":"Kritas","year":"1994","journal-title":"Veterinary Microbiology"},{"key":"10.1053\/jcpa.2000.0406_RF11","doi-asserted-by":"crossref","first-page":"2319","DOI":"10.1099\/0022-1317-75-9-2319","article-title":"Role of envelope glycoproteins gI, gp63 and gIII in the invasion and spread of Aujeszky's disease virus in the olfactory nervous pathway of the pig","volume":"75","author":"Kritas","year":"1994","journal-title":"Journal of General Virology"},{"key":"10.1053\/jcpa.2000.0406_RF12","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1006\/viro.1993.1254","article-title":"Mapping of heparin-binding structures on bovine herpesvirus 1 and pseudorabies virus gIII glycoproteins","volume":"194","author":"Liang","year":"1993","journal-title":"Virology"},{"key":"10.1053\/jcpa.2000.0406_RF13","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0378-1135(96)01305-3","article-title":"Recent developments in latency and recombination of Aujeszky's disease (pseudorabies) virus","volume":"55","author":"Maes","year":"1997","journal-title":"Veterinary Microbiology"},{"key":"10.1053\/jcpa.2000.0406_RF14","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/BF01310949","article-title":"Virus reactivation in pigs latently infected with a thymidine kinase-negative vaccine strain of pseudorabies virus","volume":"120","author":"Mengeling","year":"1991","journal-title":"Archives of Virology"},{"key":"10.1053\/jcpa.2000.0406_RF15","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0378-1135(96)01306-5","article-title":"The role of biotechnologically engineered vaccines and diagnostics in pseudorabies (Aujeszky's disease) eradication strategies","volume":"55","author":"Mengeling","year":"1997","journal-title":"Veterinary Microbiology"},{"key":"10.1053\/jcpa.2000.0406_RF16","doi-asserted-by":"crossref","first-page":"2164","DOI":"10.2460\/ajvr.1992.53.11.2164","article-title":"Effect of various vaccination procedures on shedding, latency, and reactivation of attenuated and virulent pseudorabies virus in swine","volume":"53","author":"Mengeling","year":"1992","journal-title":"American Journal of Veterinary Research"},{"key":"10.1053\/jcpa.2000.0406_RF17","doi-asserted-by":"crossref","first-page":"4030","DOI":"10.1128\/JVI.61.12.4030-4032.1987","article-title":"Role of structural glycoprotein of pseudorabies in virus virulence","volume":"61","author":"Mettenleiter","year":"1987","journal-title":"Journal of Virology"},{"key":"10.1053\/jcpa.2000.0406_RF18","doi-asserted-by":"crossref","first-page":"3095","DOI":"10.1099\/0022-1317-75-11-3095","article-title":"Glycoprotein gE-negative pseudorabies virus has a reduced capability to infect second and third-order neurons of the olfactory and trigeminal routes in the porcine central nervous system","volume":"75","author":"Mulder","year":"1994","journal-title":"Journal of General Virology"},{"key":"10.1053\/jcpa.2000.0406_RF19","first-page":"9","article-title":"Inhibition of virus-encoded thymidine kinase suppresses herpes simplex virus replication in vitro and in vivo","volume":"9","author":"Watkins","year":"1998","journal-title":"Antiviral Chemistry and Chemotherapy"},{"key":"10.1053\/jcpa.2000.0406_RF20","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0147-9571(91)90129-2","article-title":"Spread and control of Aujeszky's disease (AD)","volume":"14","author":"Wittmann","year":"1991","journal-title":"Comparative Immunology, Microbiology and Infectious Diseases"}],"container-title":["Journal of Comparative Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021997500904067?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021997500904067?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,7]],"date-time":"2024-12-07T18:57:12Z","timestamp":1733597832000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021997500904067"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,8]]},"references-count":20,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[2000,8]]}},"alternative-id":["S0021997500904067"],"URL":"https:\/\/doi.org\/10.1053\/jcpa.2000.0406","relation":{},"ISSN":["0021-9975"],"issn-type":[{"value":"0021-9975","type":"print"}],"subject":[],"published":{"date-parts":[[2000,8]]}}}