{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T13:16:16Z","timestamp":1781010976054,"version":"3.54.1"},"reference-count":27,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2000,3,1]],"date-time":"2000-03-01T00:00:00Z","timestamp":951868800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Critical Care"],"published-print":{"date-parts":[[2000,3]]},"DOI":"10.1053\/jcrc.2000.0150012","type":"journal-article","created":{"date-parts":[[2002,8,24]],"date-time":"2002-08-24T23:46:10Z","timestamp":1030232770000},"page":"12-17","source":"Crossref","is-referenced-by-count":147,"title":["The anticatabolic and wound healing effects of the testosterone analog oxandrolone after severe burn injury"],"prefix":"10.1053","volume":"15","author":[{"given":"Robert H.","family":"Demling","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis P.","family":"Orgill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/jcrc.2000.0150012_bib1","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1097\/00000658-197308000-00019","article-title":"Weight loss following thermal injury","volume":"178","author":"Newsome","year":"1973","journal-title":"Ann Surg"},{"key":"10.1053\/jcrc.2000.0150012_bib2","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/BF01660758","article-title":"Post traumatic skeletal muscle proteolysis: The role of the hormonal environment","volume":"13","author":"Bessey","year":"1989","journal-title":"World J Surg"},{"key":"10.1053\/jcrc.2000.0150012_bib3","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/0026-0495(88)90132-1","article-title":"Dynamics of the protein metabolism response to burn injury","volume":"37","author":"Jahoor","year":"1988","journal-title":"Metabolism"},{"key":"10.1053\/jcrc.2000.0150012_bib4","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1016\/S0039-6109(16)41685-3","article-title":"Metabolic changes in burned patients","volume":"58","author":"Wilmore","year":"1978","journal-title":"Surg Clin North Am"},{"key":"10.1053\/jcrc.2000.0150012_bib5","first-page":"560","article-title":"Increased peripheral amino acid release following burn injury","volume":"85","author":"Aulick","year":"1979","journal-title":"Surgery"},{"key":"10.1053\/jcrc.2000.0150012_bib6","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1056\/NEJM199109053251005","article-title":"Catabolic Illness","volume":"325","author":"Wilmore","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1053\/jcrc.2000.0150012_bib7","first-page":"290","article-title":"Weight loss with physiologic impairment, a basic indicator of surgical risk","volume":"207","author":"Windsor","year":"1992","journal-title":"Am Surg"},{"key":"10.1053\/jcrc.2000.0150012_bib8","series-title":"Growth hormone administration during nutritional support: What is to be gained, in New Horizons: Frontiers in Critical Care Nutrition","author":"Zeigler","year":"1994"},{"key":"10.1053\/jcrc.2000.0150012_bib9","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1159\/000180803","article-title":"Central hypogonadism in burned men","volume":"27","author":"Plymate","year":"1987","journal-title":"Hormone Res"},{"key":"10.1053\/jcrc.2000.0150012_bib10","first-page":"181","article-title":"Growth hormone attenuated the abnormal distribution of body water in critically ill surgical patients","volume":"112","author":"Gatzen","year":"1992","journal-title":"Surgery"},{"key":"10.1053\/jcrc.2000.0150012_bib11","first-page":"37","article-title":"Growth hormone enhances reepithelialization of human split-thickness skin graft donor sites","volume":"40","author":"Sherman","year":"1989","journal-title":"Surg Forum"},{"key":"10.1053\/jcrc.2000.0150012_bib12","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1046\/j.1524-475X.1996.40108.x","article-title":"Growth hormone increases the biochemical strength and collagen deposition rate during the early phase of skin wound healing","volume":"40","author":"Jorgensen","year":"1996","journal-title":"Wound Rep Reg"},{"key":"10.1053\/jcrc.2000.0150012_bib13","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1097\/00005373-199509000-00021","article-title":"Increased survival after major thermal injury: The effect of growth hormone therapy in adults","volume":"39","author":"Knox","year":"1995","journal-title":"J Trauma"},{"key":"10.1053\/jcrc.2000.0150012_bib14","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1002\/hep.1840170407","article-title":"A study of oral nutrition support with oxandrolone in malnourished patient with alcoholic hepatitis","volume":"17","author":"Mendelhall","year":"1993","journal-title":"Hepatology"},{"key":"10.1053\/jcrc.2000.0150012_bib15","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1097\/00005373-198205000-00011","article-title":"Effect of an anabolic steroid on nitrogen balance and amino acid patterns after total hip replacement","volume":"22","author":"Michelsen","year":"1982","journal-title":"J Trauma"},{"key":"10.1053\/jcrc.2000.0150012_bib16","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1097\/00002030-199612000-00010","article-title":"Oxandrolone in AIDS\u2014wasting myopathy","volume":"10","author":"Berger","year":"1996","journal-title":"AIDS"},{"key":"10.1053\/jcrc.2000.0150012_bib17","first-page":"119","article-title":"The effects of an anabolic hormone on surgically induced wound healing in lower extremity skeletal muscle in diabetic and normal rats","volume":"1","author":"Pitkow","year":"1993","journal-title":"Wound Rep Reg"},{"key":"10.1053\/jcrc.2000.0150012_bib18","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1097\/00005373-199707000-00012","article-title":"Oxandrolone, an anabolic steroid significantly increases the rate of weight gain in the recovery phase after major burns","volume":"43","author":"Demling","year":"1997","journal-title":"J Trauma"},{"key":"10.1053\/jcrc.2000.0150012_bib19","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1002\/cpt1973145862","article-title":"Oxandrolone disposition and metabolism in man","volume":"14","author":"Karim","year":"1973","journal-title":"Clin Pharmacol Ther"},{"key":"10.1053\/jcrc.2000.0150012_bib20","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1210\/jcem-22-9-921","article-title":"Oxandrolone: A potent anabolic steroid","volume":"22","author":"Fox","year":"1962","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1053\/jcrc.2000.0150012_bib21","first-page":"122","article-title":"What is optimum nutritional support?","volume":"vol 1","author":"DeBiasse","year":"1994"},{"key":"10.1053\/jcrc.2000.0150012_bib22","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1177\/0148607188012001100","article-title":"Assessment of an automated chemiluminescence nitrogen analyzer for routine use in clinical nutrition","volume":"12","author":"Grimble","year":"1988","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"10.1053\/jcrc.2000.0150012_bib23","first-page":"495","article-title":"Decreased growth hormone levels in the catabolic phase of severe injury","volume":"111","author":"Jeveendra","year":"1992","journal-title":"Surgery"},{"key":"10.1053\/jcrc.2000.0150012_bib24","first-page":"288","article-title":"Whole body protein kinetics in severely septic patients","volume":"205","author":"Shaw","year":"1987","journal-title":"Am Surg"},{"key":"10.1053\/jcrc.2000.0150012_bib25","first-page":"3349","article-title":"Patterns of lean and fat deposition in adults","volume":"206","author":"Dugdale","year":"1977","journal-title":"Nature"},{"key":"10.1053\/jcrc.2000.0150012_bib26","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1530\/acta.0.109S00011","article-title":"The history of anabolic steroids and a clinical review of clinical experiences","volume":"271","author":"Kopera","year":"1985","journal-title":"Acta Endocrinol"},{"key":"10.1053\/jcrc.2000.0150012_bib27","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S0140-6736(77)90949-7","article-title":"Liver damage from long term methylprednisolone","volume":"2","author":"Westaliy","year":"1977","journal-title":"Lancet"}],"container-title":["Journal of Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883944100700062?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883944100700062?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,2,6]],"date-time":"2020-02-06T15:45:54Z","timestamp":1581003954000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0883944100700062"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,3]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2000,3]]}},"alternative-id":["S0883944100700062"],"URL":"https:\/\/doi.org\/10.1053\/jcrc.2000.0150012","relation":{},"ISSN":["0883-9441"],"issn-type":[{"value":"0883-9441","type":"print"}],"subject":[],"published":{"date-parts":[[2000,3]]}}}