{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T06:30:35Z","timestamp":1790317835375,"version":"4.1.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2001,11,1]],"date-time":"2001-11-01T00:00:00Z","timestamp":1004572800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Hospital Infection"],"published-print":{"date-parts":[[2001,11]]},"DOI":"10.1053\/jhin.2001.1066","type":"journal-article","created":{"date-parts":[[2002,9,19]],"date-time":"2002-09-19T13:56:27Z","timestamp":1032443787000},"page":"183-192","source":"Crossref","is-referenced-by-count":78,"title":["A simultaneous outbreak on a neonatal unit of two strains of multiply antibiotic resistant Klebsiella pneumoniae controllable only by ward closure"],"prefix":"10.1053","volume":"49","author":[{"given":"M.B.","family":"Macrae","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.P.","family":"Shannon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.M.","family":"Rayner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.M.","family":"Kaiser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.N.","family":"Hoffman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.L.","family":"French","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/jhin.2001.1066_RF1","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1128\/CMR.11.4.589","article-title":"Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods and pathogenicity factors","volume":"11","author":"Podschun","year":"1998","journal-title":"Clin Microbiol Rev"},{"key":"10.1053\/jhin.2001.1066_RF2","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1093\/jac\/39.6.737","article-title":"Rarity of transferable \u03b2-lactamase production by Klebsiella species","volume":"39","author":"Leung","year":"1997","journal-title":"J Antimicrob Chemother"},{"key":"10.1053\/jhin.2001.1066_RF3","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1017\/S0022172400053997","article-title":"An investigation into the incidence and source of Klebsiella infections in hospital patients","volume":"82","author":"Cooke","year":"1979","journal-title":"J Hyg"},{"key":"10.1053\/jhin.2001.1066_RF4","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1017\/S0022172400026218","article-title":"Further studies on the sources of Klebsiella aerogenes in hospital patients","volume":"83","author":"Cooke","year":"1979","journal-title":"J Hyg"},{"key":"10.1053\/jhin.2001.1066_RF5","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1099\/00222615-12-2-201","article-title":"Acquisition of Klebsiella aerogenes by neonates","volume":"12","author":"Shinebaum","year":"1979","journal-title":"J Med Microbiol"},{"key":"10.1053\/jhin.2001.1066_RF6","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1097\/00006454-198609000-00009","article-title":"Fecal bacterial microflora of newborn infants during intensive care management and treatment with five antibiotic regimens","volume":"5","author":"Bennet","year":"1986","journal-title":"Ped Infect Dis"},{"key":"10.1053\/jhin.2001.1066_RF7","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1136\/bmj.2.6098.1315","article-title":"Hands as route of transmission for Klebsiella species","volume":"2","author":"Casewell","year":"1977","journal-title":"Br Med J"},{"key":"10.1053\/jhin.2001.1066_RF8","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/0002-9343(81)90788-9","article-title":"Aspects of plasmid-mediated antibiotic resistance and epidemiology of Klebsiella species","volume":"70","author":"Casewell","year":"1981","journal-title":"Am J Med"},{"key":"10.1053\/jhin.2001.1066_RF9","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1001\/archinte.1977.03630170013006","article-title":"Sequential hospital-wide outbreaks of resistant Serratia and Klebsiella infections","volume":"137","author":"Thomas","year":"1977","journal-title":"Arch Intern Med"},{"key":"10.1053\/jhin.2001.1066_RF10","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1093\/infdis\/142.1.106","article-title":"Sequential outbreaks of infection due to Klebsiella pneumoniae in a neonatal intensive care unit: implication of a conjugative R plasmid","volume":"142","author":"Markowitz","year":"1980","journal-title":"J Infect Dis"},{"key":"10.1053\/jhin.2001.1066_RF11","doi-asserted-by":"crossref","first-page":"S45","DOI":"10.1093\/infdis\/131.Supplement.S45","article-title":"Nosocomial infection caused by gentamicin-resistant streptomycin-sensitive Klebsiella","volume":"131","author":"Noreiga","year":"1975","journal-title":"J Infect Dis"},{"key":"10.1053\/jhin.2001.1066_RF12","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1128\/AAC.11.2.179","article-title":"Emergence of gentamicin-resistant Klebsiella in a general hospital","volume":"11","author":"Rennie","year":"1977","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1053\/jhin.2001.1066_RF13","first-page":"421","article-title":"Gentamicin-resistant Klebsiella infections in a neonatal intensive care unit","volume":"132","author":"Eidelman","year":"1978","journal-title":"Amer J Dis Child"},{"key":"10.1053\/jhin.2001.1066_RF14","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1542\/peds.65.2.264","article-title":"Outbreak of amikacin-resistant Enterobacteriaceae in an intensive care nursery","volume":"65","author":"Cook","year":"1980","journal-title":"Pediatrics"},{"key":"10.1053\/jhin.2001.1066_RF15","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1017\/S019594170005308X","article-title":"Nosocomial klebsiella infection in a neonatal unit: identification of risk factors for gastrointestinal colonization","volume":"1","author":"Mayhall","year":"1980","journal-title":"Infect Control"},{"key":"10.1053\/jhin.2001.1066_RF16","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1017\/S0195941700055934","article-title":"Nursery epidemic due to multiply-resistant Klebsiella pneumoniae: epidemiologic setting and impact on perinatal health care delivery","volume":"3","author":"McKee","year":"1982","journal-title":"Infect Control"},{"key":"10.1053\/jhin.2001.1066_RF17","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/BF01641355","article-title":"Transferrable resistance to cefotaxime, cefoxitin, cefamandole and cefuroxime in clinical isolates of Klebsiella pneumoniae and Serratia marcescens","volume":"11","author":"Knothe","year":"1983","journal-title":"Infection"},{"key":"10.1053\/jhin.2001.1066_RF18","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1093\/jac\/11.6.597","article-title":"E. coli and K. pneumoniae strains more susceptible to cefoxitin than to third-generation cephalosporins","volume":"11","author":"Shah","year":"1983","journal-title":"J Antimicrob Chemother"},{"key":"10.1053\/jhin.2001.1066_RF19","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1093\/jac\/20.3.323","article-title":"Transferrable resistance to third-generation cephalosporins in clinical isolates of Klebsiella pneumoniae: identification of CTX-1, a novel \u03b2-lactamase","volume":"20","author":"Sirot","year":"1987","journal-title":"J Antimicrob Chemother"},{"key":"10.1053\/jhin.2001.1066_RF20","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1128\/AAC.33.8.1131","article-title":"Extended-spectrum \u03b2-lactamases","volume":"33","author":"Philippon","year":"1989","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1053\/jhin.2001.1066_RF21","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1093\/jac\/44.3.309","article-title":"Evolution and spread of SHV extended spectrum \u03b2-lactamases in Gram-negative bacteria","volume":"44","author":"Heritage","year":"1999","journal-title":"J Antimicrob Chemother"},{"key":"10.1053\/jhin.2001.1066_RF22","unstructured":"Jacoby, GA, Sutton, L, Properties of plasmids responsible for production of extended-spectrum \u03b2-lactamases"},{"key":"10.1053\/jhin.2001.1066_RF23","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1007\/BF01967377","article-title":"Outbreak of nosocomial infections due to Klebsiella pneumoniae producing SHV-4 beta-lactamase","volume":"9","author":"Arlet","year":"1990","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1053\/jhin.2001.1066_RF24","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/0195-6701(92)90111-X","article-title":"Outbreak of infection in two UK hospitals caused by a strain of Klebsiella pneumoniae resistant to cefotaxime and ceftazidime","volume":"20","author":"Johnson","year":"1992","journal-title":"J Hosp Infect"},{"key":"10.1053\/jhin.2001.1066_RF25","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1128\/AAC.36.9.1991","article-title":"Outbreak of ceftazidime resistance due to a novel extended-spectrum beta-lactamase in isolates from cancer patients","volume":"36","author":"Naumovski","year":"1992","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1053\/jhin.2001.1066_RF26","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1007\/BF01739303","article-title":"Spread of Klebsiella pneumoniae producing SHV-5 beta-lactamase among hospitalized patients","volume":"21","author":"Bauernfeind","year":"1993","journal-title":"Infection"},{"key":"10.1053\/jhin.2001.1066_RF27","doi-asserted-by":"crossref","first-page":"353","DOI":"10.7326\/0003-4819-119-5-199309010-00001","article-title":"Nosocomial outbreak of Klebsiella infection resistant to late generation cephalosporins","volume":"119","author":"Meyer","year":"1993","journal-title":"Ann Intern Med"},{"key":"10.1053\/jhin.2001.1066_RF28","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0195-6701(96)90011-0","article-title":"An outbreak of multiply-resistant Klebsiella pneumoniae in the Grampian region of Scotland","volume":"33","author":"Hobson","year":"1996","journal-title":"J Hosp Infect"},{"key":"10.1053\/jhin.2001.1066_RF29","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/S0140-6736(87)90891-9","article-title":"Transferrable enzymatic resistance to third-generation cephalosporins during nosocomial outbreak of multiresistantKlebsiella pneumoniae","volume":"2","author":"Brun-Buisson","year":"1987","journal-title":"Lancet"},{"key":"10.1053\/jhin.2001.1066_RF30","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0195-6701(92)90044-M","article-title":"Multiresistant Klebsiella pneumoniae in a neonatal nursery: The importance of maintenance of infection control policies and procedures in the prevention of outbreaks","volume":"22","author":"Coovadia","year":"1992","journal-title":"J Hosp Infect"},{"key":"10.1053\/jhin.2001.1066_RF31","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1128\/JCM.31.2.179-184.1993","article-title":"Molecular epidemiology of plasmid spread among extended broad-spectrum beta- lactamase-producing Klebsiella pneumoniae isolates in a pediatric hospital","volume":"31","author":"Bingen","year":"1993","journal-title":"J Clin Microbiol"},{"key":"10.1053\/jhin.2001.1066_RF32","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/0195-6701(93)90115-G","article-title":"An outbreak of multiresistant Klebsiella in a neonatal intensive care unit","volume":"25","author":"Reish","year":"1993","journal-title":"J Hosp Infect"},{"key":"10.1053\/jhin.2001.1066_RF33","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1093\/clinids\/21.4.915","article-title":"Molecular epidemiology of an SHV-5 extended-spectrum beta-lactamase in Enterbacteriaceae isolated from infants in a neonatal intensive care unit","volume":"21","author":"Venezia","year":"1995","journal-title":"Clin Infect Dis"},{"key":"10.1053\/jhin.2001.1066_RF34","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1055\/s-2007-994301","article-title":"An outbreak of antibiotic multiresistant Klebsiella at the neonatal intensive care unit, Kaplan Hospital, Rehovot, Israel, November 1991 to April 1992","volume":"13","author":"Flidel-Rimon","year":"1996","journal-title":"Amer J Perinatol"},{"key":"10.1053\/jhin.2001.1066_RF35","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1128\/JCM.34.2.358-363.1996","article-title":"Hospital outbreak of Klebsiella pneumoniae resistant to broad-spectrum cephalosporins and \u03b2-lactam-\u03b2-lactamase inhibitor combinations by hyperproduction of SHV-5 \u03b2-lactamase","volume":"34","author":"French","year":"1996","journal-title":"J Clin Microbiol"},{"key":"10.1053\/jhin.2001.1066_RF36","first-page":"127","article-title":"An outbreak due to multidrug-resistant Klebsiella pneumoniae in Neonatal Intensive Care Unit","volume":"31","author":"Hosoglu","year":"1997","journal-title":"Mikrobiyoloji Bulteni"},{"key":"10.1053\/jhin.2001.1066_RF37","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1128\/JCM.36.5.1357-1360.1998","article-title":"Nosocomial outbreak of Klebsiella pneumoniae producing SHV-5 extended- spectrum beta-lactamase, originating from a contaminated ultrasonography coupling gel","volume":"36","author":"Gaillot","year":"1998","journal-title":"J Clin Microbiol"},{"key":"10.1053\/jhin.2001.1066_RF38","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1055\/s-2007-993898","article-title":"Piperacillin\/tazobactam in the treatment of Klebsiella pneumoniae infections in neonates","volume":"15","author":"Pillay","year":"1998","journal-title":"Amer J Perinatol"},{"key":"10.1053\/jhin.2001.1066_RF39","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/S0195-6701(98)90294-8","article-title":"A hospital outbreak of extended-spectrum \u03b2-lactamase-producing Klebsiella pneumoniae investigated by RAPD typing and analysis of the genetics and mechanisms of resistance","volume":"39","author":"Shannon","year":"1998","journal-title":"J Hosp Infect"},{"key":"10.1053\/jhin.2001.1066_RF40","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/S0163-4453(98)92107-7","article-title":"Molecular epidemiology as an effective tool in the surveillance of infections in the neonatal intensive care unit","volume":"37","author":"Villari","year":"1998","journal-title":"J Infect"},{"key":"10.1053\/jhin.2001.1066_RF41","series-title":"Hospital Infection Control: Policies and Practical Procedures","author":"Philpott-Howard","year":"1994"},{"key":"10.1053\/jhin.2001.1066_RF42","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1017\/S0022172400025043","article-title":"Klebsiella serotyping by countercurrent immunoelectrophoresis","volume":"18","author":"Palyfreyman","year":"1978","journal-title":"J Hyg"},{"key":"10.1053\/jhin.2001.1066_RF43","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1128\/AAC.38.3.494","article-title":"Effect of hyperproduction of TEM-1 \u03b2-lactamases on in-vitro susceptibility of Escherichia coli to \u03b2-lactam antibiotics","volume":"38","author":"Wu","year":"1994","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1053\/jhin.2001.1066_RF44","first-page":"164","article-title":"Aminoglycosides and aminocyclitols","author":"Phillips","year":"1997"},{"key":"10.1053\/jhin.2001.1066_RF45","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1017\/S0195941700055363","article-title":"Bacteriologic studies on electronic hospital thermometers","volume":"2","author":"Smith","year":"1981","journal-title":"Infect Control"},{"key":"10.1053\/jhin.2001.1066_RF46","doi-asserted-by":"crossref","first-page":"112","DOI":"10.7326\/0003-4819-117-2-112","article-title":"Hospital-acquired infection with vancomycin-resistant Enterococcus faecium transmitted by electronic thermometers","volume":"117","author":"Livornese","year":"1992","journal-title":"Ann Intern Med"},{"key":"10.1053\/jhin.2001.1066_RF47","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1093\/clinids\/3.4.716","article-title":"Contaminated breast milk: a source of Klebsiella bacteremia in a newborn intensive care unit","volume":"3","author":"Donowitz","year":"1981","journal-title":"Rev Infect Dis"},{"key":"10.1053\/jhin.2001.1066_RF48","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0195-6701(86)90057-5","article-title":"An outbreak of Serratia marcescens transmitted by contaminated breast pumps in a special care baby unit","volume":"7","author":"Gransden","year":"1986","journal-title":"J Hosp Infect"},{"key":"10.1053\/jhin.2001.1066_RF49","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1017\/S0950268899003349","article-title":"A five year outbreak of methicillin-susceptible Staphylococcus aureus phage type 53,85 in a regional neonatal unit","volume":"124","author":"Wilcox","year":"2000","journal-title":"Epidemiol Infect"},{"key":"10.1053\/jhin.2001.1066_RF50","doi-asserted-by":"crossref","first-page":"29","DOI":"10.3109\/00365548409068406","article-title":"Nosocomial Klebsiella pneumoniae infection: Clinical and hygienic measures in a neonatal intensive care unit","volume":"16","author":"Svenningsen","year":"1984","journal-title":"Scand J Infect Dis"}],"container-title":["Journal of Hospital Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0195670101910667?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0195670101910667?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,2,6]],"date-time":"2020-02-06T20:08:25Z","timestamp":1581019705000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0195670101910667"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,11]]},"references-count":50,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2001,11]]}},"alternative-id":["S0195670101910667"],"URL":"https:\/\/doi.org\/10.1053\/jhin.2001.1066","relation":{},"ISSN":["0195-6701"],"issn-type":[{"value":"0195-6701","type":"print"}],"subject":[],"published":{"date-parts":[[2001,11]]}}}