{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T13:00:51Z","timestamp":1791205251874,"version":"4.1.0"},"reference-count":20,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection"],"published-print":{"date-parts":[[2003,1]]},"DOI":"10.1053\/jinf.2002.1047","type":"journal-article","created":{"date-parts":[[2003,1,21]],"date-time":"2003-01-21T15:33:59Z","timestamp":1043163239000},"page":"49-55","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":64,"title":["Plural Transformation-Processes from Spiral to Coccoid Helicobacter pylori and its Viability"],"prefix":"10.1016","volume":"46","author":[{"given":"N.","family":"Saito","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Konishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Kato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Takeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Sugiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Asaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/jinf.2002.1047_RF1","first-page":"880","article-title":"Ueber das vorkommen von spirochaeten bei ulcerierten carcinomen","volume":"42","author":"Hoffmann","year":"1905","journal-title":"Berl Klin Wochenschr"},{"key":"10.1053\/jinf.2002.1047_RF2","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1099\/00222615-19-2-257","article-title":"Unusual cellular fatty acids and distinctive ultrastructure in a new spiral bacterium (Campylobacter pyloridis) from the human gastric mucosa","volume":"19","author":"Goodwon","year":"1985","journal-title":"J Med Microbiol"},{"key":"10.1053\/jinf.2002.1047_RF3","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1097\/00042737-199803000-00011","article-title":"Gastric ulcers and Helicobacter heilmannii","volume":"10","author":"Debongnie","year":"1998","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1053\/jinf.2002.1047_RF4","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1136\/jcp.42.6.585","article-title":"New spiral bacterium in gastric mucosa","volume":"42","author":"McNulty","year":"1989","journal-title":"J Clin Pathol"},{"key":"10.1053\/jinf.2002.1047_RF5","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1056\/NEJM199110173251603","article-title":"Helicobacter pylori infection and the risk of gastric carcinoma","volume":"325","author":"Parsonnet","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1053\/jinf.2002.1047_RF6","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1016\/0046-8177(94)90060-4","article-title":"Gastrointestinal lymphoma","volume":"25","author":"Isaacson","year":"1994","journal-title":"Hum Pathol"},{"key":"10.1053\/jinf.2002.1047_RF7","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/S0140-6736(84)91816-6","article-title":"Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration","volume":"1","author":"Marshall","year":"1984","journal-title":"Lancet"},{"key":"10.1053\/jinf.2002.1047_RF8","first-page":"4255","article-title":"Developement of Helicobacter pylori -induced gastric carcinoma in Mongolian gerbils","volume":"58","author":"Honda","year":"1998","journal-title":"Cancer Res"},{"key":"10.1053\/jinf.2002.1047_RF9","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/S0016-5085(98)70143-X","article-title":"Helicobacter pylori infection induces gastric cancer in Mongolian gerbils","volume":"115","author":"Watanabe","year":"1998","journal-title":"Gastroenterol"},{"key":"10.1053\/jinf.2002.1047_RF10","first-page":"100","article-title":"Gastric spiral bacteria","volume":"2","author":"Phillips","year":"1984","journal-title":"Lancet"},{"key":"10.1053\/jinf.2002.1047_RF11","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0934-8840(11)80964-3","article-title":"Coccoid like forms (CLF) of Helicobacter pylori. Enzyme activity and antigenicity","volume":"280","author":"Nilius","year":"1993","journal-title":"Zbl Bakt"},{"key":"10.1053\/jinf.2002.1047_RF12","first-page":"187","article-title":"Helicobacter pylori in culture: an ultrastructural study","volume":"75","author":"Sato","year":"2000","journal-title":"Hokkaido J Med Sci"},{"key":"10.1053\/jinf.2002.1047_RF13","first-page":"170","article-title":"Detection of coccoid Helicobacter pylori: light microscopical immunogold silver enhancing stain","volume":"3","author":"Saito","year":"1998","journal-title":"Helicobacter"},{"key":"10.1053\/jinf.2002.1047_RF14","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1111\/j.1699-0463.1988.tb05344.x","article-title":"Campylobacter pylori detected by indirect immunohistochemical technique","volume":"96","author":"Anderson","year":"1988","journal-title":"APMIS"},{"key":"10.1053\/jinf.2002.1047_RF15","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1006\/excr.1996.0240","article-title":"Monoclonal antibody to single-stranded DNA is a specific and sensitive cellular marker of apoptosis","volume":"226","author":"Frankfurt","year":"1996","journal-title":"Exp Cell Res"},{"key":"10.1053\/jinf.2002.1047_RF16","doi-asserted-by":"crossref","first-page":"3672","DOI":"10.1128\/iai.65.9.3672-3679.1997","article-title":"Coccoid forms of Helicobacter pylori are the morphologic manifestation of cell death","volume":"65","author":"Kusters","year":"1997","journal-title":"Infect Immun"},{"key":"10.1053\/jinf.2002.1047_RF17","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1128\/iai.64.6.2331-2335.1996","article-title":"Changes in Helicobacter pylori ultrastructure and antigens during conversion from the bacillary to the coccoid form","volume":"64","author":"Benassa","year":"1996","journal-title":"Infect Immun"},{"key":"10.1053\/jinf.2002.1047_RF18","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1128\/iai.64.3.905-912.1996","article-title":"Surface localization of Helicobacter pylori urease and a heat shock protein homolog requires bacterial autolysis","volume":"64","author":"Phadnis","year":"1996","journal-title":"Infect Immun"},{"key":"10.1053\/jinf.2002.1047_RF19","doi-asserted-by":"crossref","first-page":"2984","DOI":"10.1128\/IAI.66.6.2984-2986.1998","article-title":"Extracellular release of antigenic proteins by Helicobacter pylori","volume":"66","author":"Cao","year":"1998","journal-title":"Infect Immun"},{"key":"10.1053\/jinf.2002.1047_RF20","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1126\/science.284.5418.1328","article-title":"Helicobacter pylori virulence and genetic geography","volume":"284","author":"Covacci","year":"1999","journal-title":"Science"}],"container-title":["Journal of Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163445302910479?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163445302910479?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T15:24:57Z","timestamp":1758986697000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0163445302910479"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2003,1]]}},"alternative-id":["S0163445302910479"],"URL":"https:\/\/doi.org\/10.1053\/jinf.2002.1047","relation":{},"ISSN":["0163-4453"],"issn-type":[{"value":"0163-4453","type":"print"}],"subject":[],"published":{"date-parts":[[2003,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Plural Transformation-Processes from Spiral to Coccoid Helicobacter pylori and its Viability","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/jinf.2002.1047","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2003 The British Infection Society. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}