{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T09:09:59Z","timestamp":1760864999800,"version":"3.33.0"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":5325,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2001,2]]},"abstract":"<jats:sec>\n            <jats:title\/>\n            <jats:p>Severe veno-occlusive disease (VOD) of the liver is a leading cause of mortality after bone marrow transplantation (BMT). Vascular and parenchymal injuries account for acute portal hypertension and liver failure is frequently present. We describe the results of transjugular intrahepatic portosystemic shunt (TIPS) for the management of VOD after BMT. TIPS was performed in 10 patients with histologically proven severe VOD. Portal hypertension was controlled by TIPS in all patients (mean hepatic venous pressure gradient before, 20 \u00b1 11 vs 6 \u00b1 5 mm Hg after TIPS, P &lt; 0.01) without technical complications. Five patients with rapidly worsening VOD died within 10 days of TIPS without any improvement. The five remaining patients with less advanced disease showed improvement in various clinical and biological parameters. Four patients subsequently died. The lone survivor continues to do well with resolution of VOD 6 months after TIPS. TIPS can be performed safely and controls portal hypertension in VOD after BMT. Arguments from the present series and from eight previously reported cases favour earlier application of TIPS to obtain improved overall survival.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1053\/jlts.2001.0070154","type":"journal-article","created":{"date-parts":[[2004,3,19]],"date-time":"2004-03-19T18:49:15Z","timestamp":1079722155000},"page":"154-157","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":17,"title":["Expanding the use of transjugular intrahepatic portosystemic shunts for veno-occlusive disease"],"prefix":"10.1097","volume":"7","author":[{"given":"Pankaj","family":"Rajvanshi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George B.","family":"McDonald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"10.1053\/jlts.2001.0070154-BIB1","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1097\/00000658-199008000-00005","volume":"212","author":"Klein","year":"1990","journal-title":"Ann Surg"},{"key":"10.1053\/jlts.2001.0070154-BIB2","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0002-9610(05)80605-1","volume":"159","author":"Henderson","year":"1990","journal-title":"Am J Surg"},{"key":"10.1053\/jlts.2001.0070154-BIB3","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0168-8278(05)80249-1","volume":"18","author":"Ochs","year":"1993","journal-title":"J Hepatol"},{"key":"10.1053\/jlts.2001.0070154-BIB4","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1038\/sj.bmt.1702386","volume":"25","author":"Azoulay","year":"2000","journal-title":"Bone Marrow Transplant"},{"key":"10.1053\/jlts.2001.0070154-BIB5","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1002\/hep.510240321","volume":"24","author":"Fried","year":"1996","journal-title":"Hepatology"},{"key":"10.1053\/jlts.2001.0070154-BIB6","first-page":"536","volume":"81","author":"Rubia","year":"1996","journal-title":"Hematologica"},{"key":"10.1053\/jlts.2001.0070154-BIB7","first-page":"643","volume":"18","author":"Smith","year":"1996","journal-title":"Bone Marrow Transplant"},{"key":"10.1053\/jlts.2001.0070154-BIB8","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1002\/hep.1840190515","volume":"19","author":"Shulman","year":"1994","journal-title":"Hepatology"},{"key":"10.1053\/jlts.2001.0070154-BIB9","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1002\/hep.510240414","volume":"24","author":"DeLeve","year":"1996","journal-title":"Hepatology"},{"key":"10.1053\/jlts.2001.0070154-BIB10","first-page":"218a","volume":"30","author":"DeLeve","year":"1999","journal-title":"Hepatology"},{"key":"10.1053\/jlts.2001.0070154-BIB11","doi-asserted-by":"crossref","first-page":"255","DOI":"10.7326\/0003-4819-118-4-199302150-00003","volume":"118","author":"McDonald","year":"1993","journal-title":"Ann Intern Med"},{"key":"10.1053\/jlts.2001.0070154-BIB12","doi-asserted-by":"crossref","first-page":"625","DOI":"10.7326\/0003-4819-125-8-199610150-00001","volume":"125","author":"Rubenfeld","year":"1996","journal-title":"Ann Intern Med"},{"key":"10.1053\/jlts.2001.0070154-BIB13","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/S0272-6386(89)80054-X","volume":"13","author":"Zager","year":"1989","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/jlts.2001.0070154-BIB14","first-page":"1617","volume-title":"Schiff's diseases of the liver","author":"Strasser","year":"1999","unstructured":"Hepatobiliary complications of the hematopoietic cell transplantation. In: (eds). Schiff's diseases of the liver. 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