{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T07:54:21Z","timestamp":1770882861298,"version":"3.50.1"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":4414,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2003,8]]},"abstract":"<jats:sec>\n            <jats:title\/>\n            <jats:p>We studied the safety of right-lobe donor hepatectomy in living donors with a positive serological test result for antibody against hepatitis B core antigen (anti-HBc). Of 54 right-lobe living liver donors, serum anti-HBc was positive in 29 donors (54%) and negative in 25 donors (46%). None had a history of hepatitis and all had normal liver biochemistry test results before surgery. Surgical data, postoperative liver function, and outcome of donors were compared according to anti-HBc status. Donors positive for anti-HBc were significantly older (median age, 42 <jats:italic toggle=\"yes\">v<\/jats:italic> 31 years; <jats:italic toggle=\"yes\">P<\/jats:italic> &lt; .001), but there was no difference in other demographics and liver size. Median blood loss was greater in anti-HBc-positive donors (600 <jats:italic toggle=\"yes\">v<\/jats:italic> 350 mL; <jats:italic toggle=\"yes\">P<\/jats:italic> = .007). Histological examination showed no difference in degree of portal fibrosis or fatty change in liver grafts. There was no significant difference in postoperative serum transaminase levels or prothrombin times; however, anti-HBc-positive donors had greater serum bilirubin levels day 6 (26 <jats:italic toggle=\"yes\">v<\/jats:italic> 21 \u03bcmol\/L; <jats:italic toggle=\"yes\">P<\/jats:italic> = .01) and day 7 (22 <jats:italic toggle=\"yes\">v<\/jats:italic> 15 \u03bcmol\/L; <jats:italic toggle=\"yes\">P<\/jats:italic> = .004) after surgery. Postoperative complications developed in 10 anti-HBc-positive and 6 anti-HBc-negative donors (<jats:italic toggle=\"yes\">P<\/jats:italic> = .4). All donors who developed cholestasis were positive for anti-HBc, aged 45 years or older, and had mild fatty changes of the liver. Hospital stays were similar. All donors had completely normal liver function at a median follow-up of 31 months (range, 21 to 76 months). A positive serological test result for anti-HBc should not be regarded as a contraindication for right-lobe liver donation. (<jats:italic toggle=\"yes\">Liver Transpl 2003;9:827-832.<\/jats:italic>)<\/jats:p>\n          <\/jats:sec>","DOI":"10.1053\/jlts.2003.50115","type":"journal-article","created":{"date-parts":[[2003,7,25]],"date-time":"2003-07-25T14:08:42Z","timestamp":1059142122000},"page":"827-832","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":38,"title":["Safety and outcome of hepatitis B core antibody-positive donors in right-lobe living donor liver transplantation"],"prefix":"10.1097","volume":"9","author":[{"given":"Chung-Mau","family":"Lo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheung-Tat","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi-Leung","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boon-Hun","family":"Yong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yik","family":"Wong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene Oi-Lin","family":"Ng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Wong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"BIB1","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1056\/NEJM198501313120503","volume":"312","author":"Brechot","year":"1985","journal-title":"N Engl J Med"},{"key":"BIB2","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1097\/00007890-199501270-00014","volume":"59","author":"Wachs","year":"1995","journal-title":"Transplantation"},{"key":"BIB3","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1053\/gast.1997.v113.pm9352871","volume":"113","author":"Dickson","year":"1997","journal-title":"Gastroenterology"},{"key":"BIB4","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1097\/00007890-199712150-00013","volume":"64","author":"Dodson","year":"1997","journal-title":"Transplantation"},{"key":"BIB5","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1053\/jlts.2001.20786","volume":"7","author":"Prieto","year":"2001","journal-title":"Liver Transpl"},{"key":"BIB6","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1002\/lt.500070514","volume":"7","author":"Lee","year":"2001","journal-title":"Liver Transpl"},{"key":"BIB7","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1097\/00007890-199910150-00028","volume":"68","author":"Dodson","year":"1999","journal-title":"Transplantation"},{"key":"BIB8","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1136\/gut.50.1.95","volume":"50","author":"Roque-Afonso","year":"2002","journal-title":"Gut"},{"key":"BIB9","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1053\/jlts.2001.23911","volume":"7","author":"Yu","year":"2001","journal-title":"Liver Transpl"},{"key":"BIB10","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1097\/00007890-199802270-00007","volume":"65","author":"Uemoto","year":"1998","journal-title":"Transplantation"},{"key":"BIB11","doi-asserted-by":"crossref","first-page":"2410","DOI":"10.1097\/00007890-200006150-00034","volume":"69","author":"Marcos","year":"2000","journal-title":"Transplantation"},{"key":"BIB12","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1093\/oxfordjournals.aje.a114681","volume":"126","author":"Lok","year":"1987","journal-title":"Am J Epidemiol"},{"key":"BIB13","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1097\/00000658-199709000-00005","volume":"226","author":"Lo","year":"1997","journal-title":"Ann Surg"},{"key":"BIB14","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1001\/archsurg.135.3.336","volume":"135","author":"Fan","year":"2000","journal-title":"Arch Surg"},{"key":"BIB15","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1097\/00007890-200105270-00009","volume":"71","author":"Sakamoto","year":"2001","journal-title":"Transplantation"},{"key":"BIB16","author":"Department of health","year":"1998","unstructured":"Department of health: Public Health Report No.3 Viral Hepatitis and Liver Cancer and Unintentional Injuries in Children. 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