{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T22:22:40Z","timestamp":1767651760654,"version":"build-2065373602"},"reference-count":23,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2001,10,1]],"date-time":"2001-10-01T00:00:00Z","timestamp":1001894400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2001,10,1]],"date-time":"2001-10-01T00:00:00Z","timestamp":1001894400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T00:00:00Z","timestamp":1392595200000},"content-version":"vor","delay-in-days":4522,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","oarsijournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Osteoarthritis and Cartilage"],"published-print":{"date-parts":[[2001,10]]},"DOI":"10.1053\/joca.2001.0463","type":"journal-article","created":{"date-parts":[[2002,9,19]],"date-time":"2002-09-19T09:56:27Z","timestamp":1032429387000},"page":"664-670","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["DNA cytofluorometric analysis of chondrocytes in human articular cartilages under normal aging or arthritic conditions"],"prefix":"10.1053","volume":"9","author":[{"given":"K.","family":"Kusuzaki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Sugimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Takeshita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Murata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Hashiguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Nozaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Emoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Ashihara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Hirasawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1053\/joca.2001.0463_RF1","doi-asserted-by":"crossref","first-page":"688","DOI":"10.2106\/00004623-196244040-00009","article-title":"Localization of tritiated thymidine in articular cartilage of rabbits. II. Repair in immature cartilage","volume":"44-A","author":"Mankin","year":"1962","journal-title":"J Bone Joint Surg"},{"key":"10.1053\/joca.2001.0463_RF2","doi-asserted-by":"crossref","first-page":"529","DOI":"10.2106\/00004623-196345030-00011","article-title":"Localization of tritiated thymidine in articular cartilage of rabbits. III. Mature articular cartilage","volume":"45-A","author":"Mankin","year":"1963","journal-title":"J Bone Joint Surg"},{"key":"10.1053\/joca.2001.0463_RF3","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1097\/00003086-197205000-00032","article-title":"Mitosis in human osteoarthritic cartilage","volume":"84","author":"Hulth","year":"1972","journal-title":"Clin Orthop"},{"key":"10.1053\/joca.2001.0463_RF4","doi-asserted-by":"crossref","first-page":"979","DOI":"10.3109\/17453677508989287","article-title":"Chondrocyte mitosis in the articular cartilage of femoral heads with various diseases","volume":"46","author":"Hirotani","year":"1975","journal-title":"Acta Orthop Scand"},{"key":"10.1053\/joca.2001.0463_RF5","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/BF00265995","article-title":"An experimental study of the repair of injured articular cartilage using 3H-thymidine autoradiography","volume":"2","author":"Sakakida","year":"1978","journal-title":"Int Orthop"},{"key":"10.1053\/joca.2001.0463_RF6","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1097\/00003086-198011000-00037","article-title":"Mitosis of chondrocytes in normal adult joint cartilage","volume":"153","author":"Havdrup","year":"1980","journal-title":"Clin Orthop"},{"key":"10.1053\/joca.2001.0463_RF7","doi-asserted-by":"crossref","first-page":"460","DOI":"10.2106\/00004623-198264030-00022","article-title":"Current concepts review. The response of articular cartilage to mechanical injury","volume":"64-A","author":"Mankin","year":"1982","journal-title":"J Bone Joint Surg"},{"key":"10.1053\/joca.2001.0463_RF8","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1302\/0301-620X.55B3.588","article-title":"Chondrocyte multiplication in osteoarthritic articular cartilage","volume":"55-B","author":"Rothwell","year":"1982","journal-title":"J Bone Joint Surg"},{"key":"10.1053\/joca.2001.0463_RF9","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1267\/ahc.19.51","article-title":"Multiparametric analysis using autostage cytofluorometry","volume":"19","author":"Ashihara","year":"1986","journal-title":"Acta Histochem Cytochem"},{"key":"10.1053\/joca.2001.0463_RF10","series-title":"Recent Advances in Musculoskeletal Oncology, 1st edition","first-page":"221","article-title":"Assessment of malignancy of bone and soft tissue tumors using DNA cytofluorometry","author":"Kusuzaki","year":"1992"},{"key":"10.1053\/joca.2001.0463_RF11","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0304-3835(98)00325-5","article-title":"Cytofluorometric DNA ploidy analysis in giant cell tumors of bone: Histologic and prognostic value","volume":"136","author":"Murata","year":"1999","journal-title":"Cancer Lett"},{"key":"10.1053\/joca.2001.0463_RF12","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0304-3835(98)00336-X","article-title":"Prognostic significance of DNA ploidy pattern in osteosarcomas in association with chemotherapy","volume":"137","author":"Kusuzaki","year":"1999","journal-title":"Cancer Lett"},{"key":"10.1053\/joca.2001.0463_RF13","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0304-3835(98)00389-9","article-title":"Response of DNA ploidy to chemotherapy in primary and metastatic lesions in human osteosarcomas","volume":"138","author":"Kusuzaki","year":"1999","journal-title":"Cancer Lett"},{"key":"10.1053\/joca.2001.0463_RF14","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0304-3835(99)00092-0","article-title":"Prognostic value of DNA ploidy response to chemotherapy in human osteosarcomas","volume":"141","author":"Kusuzaki","year":"1999","journal-title":"Cancer Lett"},{"key":"10.1053\/joca.2001.0463_RF15","first-page":"863","article-title":"Usefulness of cytofluorometric DNA ploidy analysis in distinguishing benign cartilaginous tumors from chondrosarcomas","volume":"12","author":"Kusuzaki","year":"1999","journal-title":"Mod Pathol"},{"key":"10.1053\/joca.2001.0463_RF16","first-page":"175","article-title":"1958 revision of diagnostic criteria for rheumatoid arthritis","volume":"9","author":"Ropes","year":"1958","journal-title":"Bull Rheum Dis"},{"key":"10.1053\/joca.2001.0463_RF17","series-title":"Adult articular cartilage","first-page":"64","article-title":"The chondrocytes","author":"Stockwell","year":"1979"},{"key":"10.1053\/joca.2001.0463_RF18","doi-asserted-by":"crossref","first-page":"523","DOI":"10.2106\/00004623-197153030-00009","article-title":"Biochemical and metabolic abnormalities in articular cartilage from osteoarthritic human hips. II. Correlation of morphology with biochemical and metabolic data","volume":"53-A","author":"Mankin","year":"1971","journal-title":"J Bone Joint Surg"},{"key":"10.1053\/joca.2001.0463_RF19","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1053\/joca.1998.0146","article-title":"Stimulation of proteoglycan production by glucosamine sulfate in chondrocytes isolated from human osteoarthritic articular cartilage in vitro","volume":"6","author":"Bassleer","year":"1998","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1053\/joca.2001.0463_RF20","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1155\/1998\/545906","article-title":"Synovial sarcoma. Evaluation of prognosis with emphasis on the study of DNA ploidy and proliferation (PCNA and Ki-67) markers","volume":"16","author":"Lopes","year":"1998","journal-title":"Anal Cell Pathol"},{"key":"10.1053\/joca.2001.0463_RF21","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1302\/0301-620X.43B2.376","article-title":"Effect of persistent pressure on the articular cartilage","volume":"43-B","author":"Trias","year":"1961","journal-title":"J Bone Joint Surg"},{"key":"10.1053\/joca.2001.0463_RF22","first-page":"403","article-title":"Cytofluorometric analysis of nuclear DNA content under aging and diseased conditions in human organs","volume":"94","author":"Fujimoto","year":"1985","journal-title":"J Kyoto Pref Univ Med"},{"key":"10.1053\/joca.2001.0463_RF23","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1097\/00003086-197207000-00034","article-title":"Mitosis of chondrocytes in experimental osteoarthritis in rabbits","volume":"86","author":"Telhag","year":"1972","journal-title":"Clin Orthop"}],"container-title":["Osteoarthritis and Cartilage"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458401904637?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1063458401904637?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T02:58:13Z","timestamp":1761015493000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1063458401904637"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,10]]},"references-count":23,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2001,10]]}},"alternative-id":["S1063458401904637"],"URL":"https:\/\/doi.org\/10.1053\/joca.2001.0463","relation":{},"ISSN":["1063-4584"],"issn-type":[{"type":"print","value":"1063-4584"}],"subject":[],"published":{"date-parts":[[2001,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"DNA cytofluorometric analysis of chondrocytes in human articular cartilages under normal aging or arthritic conditions","name":"articletitle","label":"Article Title"},{"value":"Osteoarthritis and Cartilage","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/joca.2001.0463","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2001 OsteoArthritis Research Society International. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}