{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T14:35:22Z","timestamp":1789396522140,"version":"build-2803163510"},"reference-count":32,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pediatric Surgery"],"published-print":{"date-parts":[[2001,1]]},"DOI":"10.1053\/jpsu.2001.20029","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T11:24:42Z","timestamp":1027682682000},"page":"128-132","source":"Crossref","is-referenced-by-count":19,"title":["Upregulation of keratinocyte growth factor in the tracheal ligation lamb model of congenital diaphragmatic hernia"],"prefix":"10.1053","volume":"36","author":[{"given":"Amanda J.","family":"McCabe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrike","family":"Carlino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce A.","family":"Holm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip L.","family":"Glick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/jpsu.2001.20029_bib1","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1001\/jama.1994.03510290064038","article-title":"A prospective study of the outcome for fetuses with diaphragmatic hernia","volume":"271","author":"Harrison","year":"1994","journal-title":"JAMA"},{"key":"10.1053\/jpsu.2001.20029_bib2","doi-asserted-by":"crossref","first-page":"413","DOI":"10.2214\/ajr.103.2.413","article-title":"The role of pulmonary hypoplasia in the prognosis of newborn infants with diaphragmatic hernia and eventration","volume":"103","author":"Berdon","year":"1968","journal-title":"Am J Roentgenol"},{"key":"10.1053\/jpsu.2001.20029_bib3","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1097\/00000658-198312000-00016","article-title":"The mortality of congenital diaphragmatic hernia: Is total pulmonary mass inadequate, no matter what?","volume":"198","author":"Nguyen","year":"1983","journal-title":"Ann Surg"},{"key":"10.1053\/jpsu.2001.20029_bib4","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0022-3468(85)80219-0","article-title":"Diaphragmatic hernia in the fetus: Prenatal diagnosis and outcome in 94 cases","volume":"20","author":"Adzick","year":"1985","journal-title":"J Pediatr Surg"},{"key":"10.1053\/jpsu.2001.20029_bib5","first-page":"174","article-title":"Correction of congenital diaphragmatic hernia in utero I. The Model: Intrathoracic balloon produces fatal pulmonary hypoplasia","volume":"88","author":"Harrison","year":"1980","journal-title":"Surgery"},{"key":"10.1053\/jpsu.2001.20029_bib6","first-page":"649","article-title":"Morphological effects of chronic tracheal ligation and drainage in the fetal lamb lung","volume":"123","author":"Alcorn","year":"1977","journal-title":"J Anat"},{"key":"10.1053\/jpsu.2001.20029_bib7","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/S0022-3468(84)80349-8","article-title":"Experimental pulmonary hypoplasia and oligohydramnios: Relative contributions of lung fluid and fetal breathing movements","volume":"19","author":"Adzick","year":"1984","journal-title":"J Pediatr Surg"},{"key":"10.1053\/jpsu.2001.20029_bib8","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1016\/0022-3468(93)90426-L","article-title":"Experimental fetal tracheal ligation prevents the pulmonary hypoplasia associated with fetal nephrectomy: Possible application for congenital diaphragmatic hernia","volume":"28","author":"Wilson","year":"1993","journal-title":"J Pediatr Surg"},{"key":"10.1053\/jpsu.2001.20029_bib9","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/0022-3468(94)90724-2","article-title":"Plug the lung until it grows (PLUG): A new method to treat congenital diaphragmatic hernia in utero","volume":"29","author":"Hedrick","year":"1994","journal-title":"J Pediatr Surg"},{"key":"10.1053\/jpsu.2001.20029_bib10","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/S0022-3468(98)90524-3","article-title":"Correction of congenital diaphragmatic hernia in utero IX; Fetuses with poor prognosis (Liver herniation and low lung-to-head ratio) can be saved by fetoscopic temporary tracheal occlusion","volume":"33","author":"Harrison","year":"1998","journal-title":"J Pediatr Surg"},{"key":"10.1053\/jpsu.2001.20029_bib11","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0022-3468(94)90328-X","article-title":"Experimental fetal tracheal ligation reverses the structural and physiological effects of pulmonary hypoplasia in congenital diaphragmatic hernia","volume":"29","author":"DiFiore","year":"1994","journal-title":"J Pediatr Surg"},{"key":"10.1053\/jpsu.2001.20029_bib12","first-page":"376","article-title":"Stimulation of fetal rat lung cell proliferation in vitro by mechanical stretch","volume":"263","author":"Liu","year":"1992","journal-title":"Am J Physiol"},{"key":"10.1053\/jpsu.2001.20029_bib13","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0022-3468(97)90208-6","article-title":"Fetal lung growth after tracheal ligation is not solely a pressure phenomenon","volume":"32","author":"Papadakis","year":"1997","journal-title":"J Pediatr Surg"},{"key":"10.1053\/jpsu.2001.20029_bib14","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1097\/00008480-199906000-00002","article-title":"Current concepts on lung development","volume":"11","author":"Warburton","year":"1999","journal-title":"Curr Opin Pediatr"},{"key":"10.1053\/jpsu.2001.20029_bib15","doi-asserted-by":"crossref","first-page":"3107","DOI":"10.1242\/dev.122.10.3107","article-title":"Keratinocyte growth factor and its receptor are involved in regulating early lung branching","volume":"122","author":"Post","year":"1996","journal-title":"Development"},{"key":"10.1053\/jpsu.2001.20029_bib16","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1172\/JCI116673","article-title":"Keratinocyte growth factor and hepatocyte growth factor are heparin-binding factors for alveolar type II cells in fibroblast-conditioned medium","volume":"92","author":"Panos","year":"1993","journal-title":"J Clin Invest"},{"key":"10.1053\/jpsu.2001.20029_bib17","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1172\/JCI117086","article-title":"Keratinocyte growth factor is a growth factor for type II pneumocytes in vivo","volume":"93","author":"Ulich","year":"1994","journal-title":"J Clin Invest"},{"key":"10.1053\/jpsu.2001.20029_bib18","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/0022-3468(92)90865-5","article-title":"Pathophysiology of congenital diaphragmatic hernia II. The fetal lamb model is surfactant deficient","volume":"27","author":"Glick","year":"1992","journal-title":"J Pediatr Surg"},{"key":"10.1053\/jpsu.2001.20029_bib19","first-page":"12","article-title":"Hypoplastic lungs in fetal lambs with surgically produced diaphragmatic hernia","volume":"62","author":"de Lorimier","year":"1967","journal-title":"Surgery"},{"key":"10.1053\/jpsu.2001.20029_bib20","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/S0022-3468(85)80022-1","article-title":"Correction of congenital diaphragmatic hernia in utero IV. An early gestational fetal lamb model for pulmonary vascular morphometric analysis","volume":"20","author":"Adzick","year":"1985","journal-title":"J Pediatr Surg"},{"key":"10.1053\/jpsu.2001.20029_bib21","first-page":"L625","article-title":"Induction of A and D type cyclins and cdc2 kinase activity during recovery from short-term hyperoxic lung injury","volume":"12","author":"Bui","year":"1995","journal-title":"Am J Physiol"},{"key":"10.1053\/jpsu.2001.20029_bib22","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the folin phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"J Biol Chem"},{"key":"10.1053\/jpsu.2001.20029_bib23","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1007\/BF02722956","article-title":"Keratinocyte growth factor and keratinocyte growth factor receptor orthologs [monkey, pig, rabbit]","volume":"32","author":"Doyle","year":"1996","journal-title":"In Vitro Cell Dev Biol"},{"key":"10.1053\/jpsu.2001.20029_bib24","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1093\/nar\/19.2.398","article-title":"A simple method for cloning blunt ended DNA fragments","volume":"19","author":"Bhat","year":"1991","journal-title":"Nucl Acids Res"},{"key":"10.1053\/jpsu.2001.20029_bib25","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0003-2697(87)90021-2","article-title":"Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction","volume":"162","author":"Chomczynski","year":"1987","journal-title":"Analyt Biochem"},{"key":"10.1053\/jpsu.2001.20029_bib26","series-title":"Alkaline lysis DNA preparation, in Current Protocols in Molecular Biology","author":"Ausbel","year":"1999"},{"key":"10.1053\/jpsu.2001.20029_bib27","first-page":"A665","article-title":"Keratinocyte and platelet derived growth factors in the tracheal ligation lamb model of congenital diaphragmatic hernia","volume":"159","author":"McCabe","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1053\/jpsu.2001.20029_bib28","first-page":"L178","article-title":"Antisense oligonucleotides for PDGF-BB and its receptor inhibit mechanical strain-induced fetal lung cell growth","volume":"269","author":"Liu","year":"1995","journal-title":"Am J Physiol"},{"key":"10.1053\/jpsu.2001.20029_bib29","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/S0022-3468(96)90493-5","article-title":"Tracheal ligation does not correct the surfactant deficiency associated with congenital diaphragmatic hernia","volume":"31","author":"O'Toole","year":"1996","journal-title":"J Pediatr Surg"},{"key":"10.1053\/jpsu.2001.20029_bib30","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1203\/00006450-199704000-00004","article-title":"Deleterious effect of tracheal obstruction on type II pneumocytes in fetal sheep","volume":"41","author":"Piedboeuf","year":"1997","journal-title":"Pediatr Res"},{"key":"10.1053\/jpsu.2001.20029_bib31","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1203\/00006450-199705000-00014","article-title":"Contributions by individual lungs to the surfactant status in congenital diaphragmatic hernia","volume":"41","author":"Wilcox","year":"1997","journal-title":"Pediatr Res"},{"key":"10.1053\/jpsu.2001.20029_bib32","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1165\/ajrcmb.21.1.3511","article-title":"Lung growth response after tracheal occlusion in fetal rabbits is gestational age-dependent","volume":"21","author":"Paepe","year":"1999","journal-title":"Am J Respir Cell Biol"}],"container-title":["Journal of Pediatric Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022346801557541?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022346801557541?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,16]],"date-time":"2021-05-16T06:22:38Z","timestamp":1621146158000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022346801557541"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,1]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,1]]}},"alternative-id":["S0022346801557541"],"URL":"https:\/\/doi.org\/10.1053\/jpsu.2001.20029","relation":{},"ISSN":["0022-3468"],"issn-type":[{"value":"0022-3468","type":"print"}],"subject":[],"published":{"date-parts":[[2001,1]]}}}