{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T03:44:37Z","timestamp":1789789477045,"version":"4.0.1"},"reference-count":36,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2003,4,1]],"date-time":"2003-04-01T00:00:00Z","timestamp":1049155200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pediatric Surgery"],"published-print":{"date-parts":[[2003,4]]},"DOI":"10.1053\/jpsu.2003.50130","type":"journal-article","created":{"date-parts":[[2003,5,1]],"date-time":"2003-05-01T01:44:22Z","timestamp":1051753462000},"page":"597-603","source":"Crossref","is-referenced-by-count":35,"title":["Surgical interventions in children with meningococcal purpura fulminans\u2014a review of 117 procedures in 21 children"],"prefix":"10.1053","volume":"38","author":[{"given":"Jonathan Simon","family":"Wheeler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian Joseph","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tristain M.B.","family":"De Chalain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/jpsu.2003.50130_bib1","first-page":"134","article-title":"Meningococcal disease and meningitis: A review of deaths proceeding to coroner directed autopsy in Auckland [see comments]","volume":"112","author":"John","year":"1999","journal-title":"N Z Med J"},{"key":"10.1053\/jpsu.2003.50130_bib2","first-page":"257","article-title":"Epidemic meningococcal disease in New Zealand: Epidemiology and potential for prevention by vaccine","volume":"112","author":"Bremner","year":"1999","journal-title":"N Z Med J"},{"key":"10.1053\/jpsu.2003.50130_bib3","first-page":"115","article-title":"Meningococcal disease in Auckland, July 1992-June 1994 [see comments]","volume":"112","author":"Jefferies","year":"1999","journal-title":"N Z Med J"},{"key":"10.1053\/jpsu.2003.50130_bib4","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1097\/00006454-199408000-00011","article-title":"Surgical intervention for the complications of meningococcal-induced purpura fulminans [see comments]","volume":"13","author":"Herrera","year":"1994","journal-title":"Pediatr Infect Dis J"},{"key":"10.1053\/jpsu.2003.50130_bib5","first-page":"224","article-title":"Meningococcal infections in children: A review of 100 cases","volume":"8","author":"Wong","year":"1989","journal-title":"Pediatr Infect Dis J"},{"key":"10.1053\/jpsu.2003.50130_bib6","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/0002-9610(86)90542-8","article-title":"Surgical management of life-threatening and disfiguring sequelae of fulminant meningococcemia","volume":"151","author":"Schaller","year":"1986","journal-title":"Am J Surg"},{"key":"10.1053\/jpsu.2003.50130_bib7","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1093\/clinids\/17.2.254","article-title":"Epidemic meningococcemia and purpura fulminans with induced protein C deficiency","volume":"17","author":"Powars","year":"1993","journal-title":"Clin Infect Dis"},{"key":"10.1053\/jpsu.2003.50130_bib8","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/0002-9610(82)90106-4","article-title":"Purpura fulminans","volume":"143","author":"Chu","year":"1982","journal-title":"Am J Surg"},{"key":"10.1053\/jpsu.2003.50130_bib9","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/BF01712247","article-title":"The outcome of children admitted to intensive care with meningococcal septicaemia","volume":"22","author":"Mok","year":"1996","journal-title":"Intensive Care Med"},{"key":"10.1053\/jpsu.2003.50130_bib10","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1093\/infdis\/166.3.650","article-title":"Compartmentalization of lipopolysaccharide production correlates with clinical presentation in meningococcal disease","volume":"166","author":"Brandtzaeg","year":"1992","journal-title":"J Infect Dis"},{"key":"10.1053\/jpsu.2003.50130_bib11","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1055\/s-2007-1002684","article-title":"Acquired purpura fulminans","volume":"16","author":"Francis","year":"1990","journal-title":"Semin Thromb Hemost"},{"key":"10.1053\/jpsu.2003.50130_bib12","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1097\/00004630-199803000-00006","article-title":"Purpura fulminans: A disease best managed in a burn center","volume":"19","author":"Brown","year":"1998","journal-title":"J Burn Care Rehabil"},{"key":"10.1053\/jpsu.2003.50130_bib13","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1055\/s-2007-1002686","article-title":"Proposed classification and pathologic mechanisms of purpura fulminans and skin necrosis","volume":"16","author":"Adcock","year":"1990","journal-title":"Semin Thromb Hemost"},{"key":"10.1053\/jpsu.2003.50130_bib14","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1177\/0310057X9602400212","article-title":"Acute meningococcemia: Recent advances in management (with particular reference to children)","volume":"24","author":"Kennedy","year":"1996","journal-title":"Anaesth Intensive Care"},{"key":"10.1053\/jpsu.2003.50130_bib15","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1097\/00003086-198503000-00030","article-title":"Purpura fulminans. Medical, surgical, and rehabilitative considerations","volume":"193","author":"Silbart","year":"1985","journal-title":"Clin Orthop"},{"key":"10.1053\/jpsu.2003.50130_bib16","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1097\/00004630-199807000-00010","article-title":"Integra Artificial Skin as a useful adjunct in the treatment of purpura fulminans","volume":"19","author":"Besner","year":"1998","journal-title":"J Burn Care Rehabil"},{"key":"10.1053\/jpsu.2003.50130_bib17","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/0305-4179(94)90047-7","article-title":"Skin and extremity loss in meningococcal septicaemia treated in a burn unit","volume":"20","author":"Harris","year":"1994","journal-title":"Burns"},{"key":"10.1053\/jpsu.2003.50130_bib18","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1111\/j.1651-2227.1997.tb14859.x","article-title":"Severe skin loss after meningococcal septicaemia: Complications in treatment","volume":"86","author":"Huang","year":"1997","journal-title":"Acta Paediatr"},{"key":"10.1053\/jpsu.2003.50130_bib19","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1054\/bjps.1999.3249","article-title":"Meningococcal septicaemia and plastic surgery\u2014A strategy for management","volume":"53","author":"Potokar","year":"2000","journal-title":"Br J Plast Surg"},{"key":"10.1053\/jpsu.2003.50130_bib20","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/j.1600-0609.1964.tb00014.x","article-title":"Purpura fulminans: Report of a case successfully treated with heparin and hydrocortisone: Review of fifty cases from the literature","volume":"1","author":"Hjort","year":"1964","journal-title":"Scand J Haematol"},{"key":"10.1053\/jpsu.2003.50130_bib21","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/S0266-7681(97)80414-7","article-title":"Peripheral gangrene associated with fulminating meningococcal septicaemia","volume":"22B","author":"Fritton","year":"1997","journal-title":"J Hand Surg (Br)"},{"key":"10.1053\/jpsu.2003.50130_bib22","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/S0022-3468(99)90082-9","article-title":"Reconstructive surgery in children after meningococcal purpura fulminans","volume":"34","author":"Huang","year":"1999","journal-title":"J Pediatr Surg"},{"key":"10.1053\/jpsu.2003.50130_bib23","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/S0022-3468(99)90082-9","article-title":"Reconstructive surgery in children after meningococcal purpura fulminans","volume":"34","author":"Huang","year":"1999","journal-title":"J Pediatr Surg"},{"key":"10.1053\/jpsu.2003.50130_bib24","doi-asserted-by":"crossref","first-page":"920","DOI":"10.2106\/00004623-198971060-00018","article-title":"Chondro-osseous growth abnormalities after meningococcemia. A clinical and histopathological study","volume":"71","author":"Grogan","year":"1989","journal-title":"J Bone Joint Surg [Am]"},{"key":"10.1053\/jpsu.2003.50130_bib25","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1097\/00006534-199205000-00015","article-title":"Extremity amputations in meningococcemia-induced purpura fulminans","volume":"89","author":"Genoff","year":"1992","journal-title":"Plast Reconstr Surg"},{"key":"10.1053\/jpsu.2003.50130_bib26","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1177\/000992288902800208","article-title":"Purpura fulminans. A case for heparin therapy","volume":"28","author":"Chenaille","year":"1989","journal-title":"Clin Pediatr (Phila)"},{"key":"10.1053\/jpsu.2003.50130_bib27","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1055\/s-0038-1651669","article-title":"Coagulation activation and tissue necrosis in meningococcal septic shock: Severely reduced protein C levels predict a high mortality","volume":"73","author":"Fijnvandraat","year":"1995","journal-title":"Thromb Haemost"},{"key":"10.1053\/jpsu.2003.50130_bib28","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1097\/00003246-199101000-00025","article-title":"Digital ischemia complicating pneumococcal sepsis: Reversal with sympathetic blockade","volume":"19","author":"Johansen","year":"1991","journal-title":"Crit Care Med"},{"key":"10.1053\/jpsu.2003.50130_bib29","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1097\/00000637-199509000-00014","article-title":"Successful use of leeches in the treatment of purpura fulminans","volume":"35","author":"de Chalain","year":"1995","journal-title":"Ann Plast Surg"},{"key":"10.1053\/jpsu.2003.50130_bib30","doi-asserted-by":"crossref","first-page":"E53","DOI":"10.1542\/peds.102.5.e53","article-title":"Hyperbaric oxygen therapy in the pediatric patient: The experience of the Israel Naval Medical Institute","volume":"102","author":"Waisman","year":"1998","journal-title":"Pediatrics"},{"key":"10.1053\/jpsu.2003.50130_bib31","doi-asserted-by":"crossref","first-page":"S60","DOI":"10.1097\/00003246-200009001-00013","article-title":"Do new strategies in meningococcemia produce better outcomes?","volume":"28","author":"Leclerc","year":"2000","journal-title":"Crit Care Med"},{"key":"10.1053\/jpsu.2003.50130_bib32","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1056\/NEJM196512162732506","article-title":"Bleeding due to increased intravascular blood coagulation","volume":"273","author":"Rodriguez-Erdman","year":"1965","journal-title":"N Eng?Med J"},{"key":"10.1053\/jpsu.2003.50130_bib33","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1097\/00006454-199410000-00004","article-title":"The role of heparin in prevention of extremity and digit necrosis in meningococcal purpura fulminans","volume":"13","author":"Kupperman","year":"1994","journal-title":"Pediatr Infect Dis J"},{"key":"10.1053\/jpsu.2003.50130_bib34","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1097\/00006534-199703000-00044","article-title":"Free-muscle-flap coverage of exposed knee joints following fulminant meningococcemia [see comments]","volume":"99","author":"Yuen","year":"1997","journal-title":"Plast Reconstr Surg"},{"key":"10.1053\/jpsu.2003.50130_bib35","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1053\/jhsu.2000.6926","article-title":"The use of simultaneous free latissimus dorsi tissue transfers for reconstruction of bilateral upper extremities in a case of purpura fulminans","volume":"25","author":"Redett","year":"2000","journal-title":"J Hand Surg [Am]"},{"key":"10.1053\/jpsu.2003.50130_bib36","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1097\/00003246-199009000-00011","article-title":"Long-term outcome of children after intensive care","volume":"18","author":"Butt","year":"1990","journal-title":"Crit Care Med"}],"container-title":["Journal of Pediatric Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022346802631392?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022346802631392?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T02:22:48Z","timestamp":1682475768000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022346802631392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,4]]},"references-count":36,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2003,4]]}},"alternative-id":["S0022346802631392"],"URL":"https:\/\/doi.org\/10.1053\/jpsu.2003.50130","relation":{},"ISSN":["0022-3468"],"issn-type":[{"value":"0022-3468","type":"print"}],"subject":[],"published":{"date-parts":[[2003,4]]}}}