{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T04:22:47Z","timestamp":1768623767998,"version":"3.49.0"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2004,4,29]],"date-time":"2004-04-29T00:00:00Z","timestamp":1083196800000},"content-version":"vor","delay-in-days":1398,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2000,7]]},"abstract":"<jats:p><jats:bold>Objective\u2014<\/jats:bold>To examine the effect of cordopexy, laryngoplasty, and cordopexy combined with a modified laryngoplasty on airway mechanics.<\/jats:p><jats:p><jats:bold>Study Design\u2014<\/jats:bold>Experimental airway mechanics were determined by subjecting equine cadaveric larynges to airflows similar to inspiratory airflow of exercising horses.<\/jats:p><jats:p><jats:bold>Animals or Sample Population\u2014<\/jats:bold>Twenty equine larynges.<\/jats:p><jats:p><jats:bold>Methods\u2014<\/jats:bold>Using cadaveric larynges, we developed and tested a new technique of arytenoid cartilage abduction. All larynges had the right arytenoid cartilage abducted to mimic the degree of arytenoid abduction that occurs at maximal exertion in live horses. Three surgical techniques were used to stabilize the left arytenoid cartilage of treated larynges; the left arytenoid cartilage was not stabilized in control larynges. Technique 1: Cordopexy\u2014a suture was placed between the vocal ligament and the lamina of the thyroid cartilage. Technique 2: Standard laryngoplasty\u2014a suture was placed between the muscular process of the arytenoid cartilage and the caudomedial aspect of the cricoid cartilage. Technique 3: Cordopexy plus modified laryngoplasty\u2014the cordopexy suture was placed with a second suture between the horizontal ridge rostral to the muscular process of the left arytenoid cartilage and the lamina of the thyroid cartilage. Translaryngeal impedances (TI) were determined for each surgical technique by subjecting the larynges to increasing airflows and measuring the translaryngeal pressure differences. The arytenoid right to left angle quotient (RLQ) and the glottic cross\u2010sectional area (CSA) were also measured.<\/jats:p><jats:p><jats:bold>Results\u2014<\/jats:bold>At maximal airflow, the adjusted means for the arytenoid RLQ and the TI for the cordopexy plus modified laryngoplasty (1.48 \u00b1 0.04, 0.69 \u00b1 0.05 cm H<jats:sub>2<\/jats:sub>O\/L\/s) and the standard laryngoplasty (1.39 \u00b1 0.04, 0.78 cm H<jats:sub>2<\/jats:sub>O\/L\/s,) were different (<jats:styled-content><jats:italic>P<\/jats:italic>&lt; .05<\/jats:styled-content>) from values obtained after cordopexy alone (2.74 \u00b1 0.37, 1.76 \u00b1 0.48 cm H<jats:sub>2<\/jats:sub>O\/L\/s) or in control larynges (3.66 \u00b1 0.54, 4.16 \u00b1 0.96 cm H<jats:sub>2<\/jats:sub>O\/L\/s). Overall, a cordopexy plus modified laryngoplasty (9.69 cm<jats:sup>2<\/jats:sup>), a standard laryngoplasty (9.34 cm<jats:sup>2<\/jats:sup>), and a cordopexy alone (9 cm<jats:sup>2<\/jats:sup>) resulted in an increased glottic CSA greater than that for control larynges (6.94 cm<jats:sup>2<\/jats:sup>;<jats:styled-content><jats:italic>P<\/jats:italic>= .0001<\/jats:styled-content>).<\/jats:p><jats:p><jats:bold>Conclusions\u2014<\/jats:bold>Cordopexy alone did not improve airflow in a left laryngeal hemiplegic model. Cordopexy plus modified laryngoplasty was as efficacious as the standard laryngoplasty in alleviating the effects of left laryngeal hemiplegia on TI, glottic CSA, and arytenoid RLQ.<\/jats:p><jats:p><jats:bold>Clinical Relevance\u2014<\/jats:bold>Fixation of the vocal cord (cordopexy) in addition to a laryngoplasty procedure may prove useful in the surgical treatment of equine laryngeal hemiplegia.<\/jats:p>","DOI":"10.1053\/jvet.2000.5599","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T03:46:10Z","timestamp":1030247170000},"page":"326-334","source":"Crossref","is-referenced-by-count":26,"title":["An In Vitro Comparison of Cordopexy, Cordopexy and Laryngoplasty, and Laryngoplasty for Treatment of Equine Laryngeal Hemiplegia"],"prefix":"10.1111","volume":"29","author":[{"given":"Nicolai","family":"Jansson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norm G.","family":"Ducharme","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard P.","family":"Hackett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hussni O.","family":"Mohammed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,4,29]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1970.tb04179.x"},{"key":"e_1_2_5_3_2","first-page":"157","article-title":"Use of a prosthetic device for surgical correction of laryngeal hemiplegia in horses","volume":"157","author":"Marks D","year":"1970","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_5_4_2","first-page":"123","article-title":"Laryngoplasty\u2014An evaluation of three abductor muscle prosthetics","volume":"19","author":"Merriam JG","year":"1973","journal-title":"Proc Am Assoc Equine Practnr"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1080\/00480169.1982.34857"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1983.tb02812.x"},{"key":"e_1_2_5_7_2","first-page":"202","volume-title":"Equine Surgery\u2014Advanced Techniques","author":"McIlwraith CW","year":"1987"},{"key":"e_1_2_5_8_2","first-page":"27","article-title":"Technik und Ergebnisse der chirurgischen Behandlung von 398 Kehlkopfpfeifern nach einer modifizierten Mackay\u2010Smith\u2010Methode","volume":"3","author":"N\u00e9meth F","year":"1987","journal-title":"Pherdeheilkunde"},{"key":"e_1_2_5_9_2","first-page":"16","article-title":"Effect of laryngeal hemiplegia and laryngoplasty on airway flow mechanics in exercising horses","volume":"47","author":"Derksen FJ","year":"1986","journal-title":"Am J Vet Res"},{"key":"e_1_2_5_10_2","first-page":"1760","article-title":"Effects of ventriculectomy, prosthetic laryngoplasty, and exercise on upper airway function in horses with induced left laryngeal hemiplegia","volume":"49","author":"Shappell KK","year":"1988","journal-title":"Am J Vet Res"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.1990.tb01155.x"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.1990.tb01156.x"},{"key":"e_1_2_5_13_2","first-page":"335","article-title":"A retrospective survey of the racing performance of Australian horses after surgery for carpal injuries and laryngeal hemiplegia","volume":"26","author":"Speirs VC","year":"1980","journal-title":"Proc Am Assoc Equine Pract"},{"key":"e_1_2_5_14_2","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.2460\/javma.1994.204.08.1235","article-title":"Performance analysis after prosthetic laryngoplasty and bilateral ventriculectomy for laryngeal hemiplegia in horses: 70 cases (1986\u20131991)","volume":"204","author":"Russell AP","year":"1994","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1979.tb01328.x"},{"key":"e_1_2_5_16_2","doi-asserted-by":"crossref","first-page":"114","DOI":"10.2460\/ajvr.1990.51.01.114","article-title":"Effects of age and prosthesis material on in vitro cartilage retention of laryngoplasty prostheses in horses","volume":"51","author":"Dean PW","year":"1990","journal-title":"Am J Vet Res"},{"key":"e_1_2_5_17_2","first-page":"472","article-title":"The value of surgical treatment of laryngeal hemiplegia in horses","volume":"13","author":"Ducharme NG","year":"1991","journal-title":"Compend Contin Educ Pract Vet"},{"key":"e_1_2_5_18_2","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.2460\/ajvr.1996.57.11.1668","article-title":"Efficacy of prosthetic laryngoplasty with and without bilateral ventriculocordectomy as treatments for laryngeal hemiplegia in horses","volume":"57","author":"Tetens J","year":"1996","journal-title":"Am J Vet Res"},{"key":"e_1_2_5_19_2","volume-title":"Master's thesis","author":"Edwards RB","year":"1996"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.1996.tb01387.x"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9416(84)90141-6"},{"key":"e_1_2_5_22_2","first-page":"56","article-title":"Idiopathische Hemiplegia Laryngis (IHL) beim Pferd\u2014Diagnostik und Aspekte der Vererbung","volume":"11","author":"Herholz C","year":"1995","journal-title":"Swiss Vet"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.1983.tb00742.x"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.1991.tb00319.x"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1993.tb03008.x"},{"key":"e_1_2_5_26_2","doi-asserted-by":"crossref","first-page":"897","DOI":"10.2460\/ajvr.1997.58.08.897","article-title":"Effects of airway obstruction on transmural pulmonary artery pressure in exercising horses","volume":"58","author":"Jackson J","year":"1997","journal-title":"Am J Vet Res"},{"key":"e_1_2_5_27_2","first-page":"349","volume-title":"Equine Surgery","author":"Stick JA","year":"1999"}],"container-title":["Veterinary Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1053%2Fjvet.2000.5599","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1053\/jvet.2000.5599","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,7]],"date-time":"2024-12-07T19:05:56Z","timestamp":1733598356000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1053\/jvet.2000.5599"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,7]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2000,7]]}},"alternative-id":["10.1053\/jvet.2000.5599"],"URL":"https:\/\/doi.org\/10.1053\/jvet.2000.5599","archive":["Portico"],"relation":{},"ISSN":["0161-3499","1532-950X"],"issn-type":[{"value":"0161-3499","type":"print"},{"value":"1532-950X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,7]]}}}