{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T17:46:54Z","timestamp":1791136014850,"version":"4.1.0"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2000,3,1]],"date-time":"2000-03-01T00:00:00Z","timestamp":951868800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2000,3,1]],"date-time":"2000-03-01T00:00:00Z","timestamp":951868800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Placenta"],"published-print":{"date-parts":[[2000,3]]},"DOI":"10.1053\/plac.1999.0516","type":"journal-article","created":{"date-parts":[[2002,9,19]],"date-time":"2002-09-19T10:55:08Z","timestamp":1032432908000},"page":"S61-S68","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"SA","title":["Cell\u2013Cell-Communication during Placental Development and Possible Implications for Trophoblast Proliferation and Differentiation"],"prefix":"10.1016","volume":"21","author":[{"given":"E.","family":"Winterhager","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Kaufmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Gruemmer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/plac.1999.0516_RF1","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1093\/humrep\/14.2.496","article-title":"Are human placental bed giant cells merely aggregates of small monocuclear trophoblast cells? An ultrastructural and immunocytochemical study","volume":"14","author":"al-Lamki","year":"1999","journal-title":"Hum Reprod"},{"key":"10.1053\/plac.1999.0516_RF2","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1161\/01.RES.73.6.1138","article-title":"Gap junction protein connexin40 is preferentially expressed in vascular endothelium and conductive bundles of rat myocardium and is increased under hypertensive conditions","volume":"73","author":"Bastide","year":"1993","journal-title":"Circulation Res"},{"key":"10.1053\/plac.1999.0516_RF3","doi-asserted-by":"crossref","first-page":"2621","DOI":"10.1083\/jcb.105.6.2621","article-title":"Molecular Cloning of cDNA for Rat Liver Gap Junction Protein","volume":"105","author":"Beyer","year":"1987","journal-title":"J Cell Biol"},{"key":"10.1053\/plac.1999.0516_RF4","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1210\/endo.135.1.8013377","article-title":"Gap junctional differentiation during human trophoblast differentiation: influence of human chorionic ganodotropin","volume":"135","author":"Cronier","year":"1994","journal-title":"Endocrinology"},{"key":"10.1053\/plac.1999.0516_RF5","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1002\/(SICI)1097-0029(19970701\/15)38:1\/2<21::AID-JEMT4>3.0.CO;2-X","article-title":"Regulation of gap junctional communication during human trophoblast differentiation","volume":"38","author":"Cronier","year":"1997","journal-title":"Microsc Res Tech"},{"key":"10.1053\/plac.1999.0516_RF6","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/S0955-0674(98)80043-4","article-title":"Trophoblast pseudo-vasculogenesis: faking it with endothelial adhesion receptors","volume":"10","author":"Damsky","year":"1998","journal-title":"Curr Opin Cell Biol"},{"key":"10.1053\/plac.1999.0516_RF7","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1083\/jcb.129.3.805","article-title":"Specific permeability and selective formation of gap junction channels in connexin-transfected HeLa cells","volume":"129","author":"Elfgang","year":"1995","journal-title":"J Cell Biol"},{"key":"10.1053\/plac.1999.0516_RF8","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1083\/jcb.140.6.1453","article-title":"Transplacental uptake of glucose is decreased in embryonic lethal connexin26-deficient mice","volume":"140","author":"Gabriel","year":"1998","journal-title":"J Cell Biol"},{"key":"10.1053\/plac.1999.0516_RF9","first-page":"226","article-title":"Gap junctional intercellular communication in the mouse ovarian follicle","volume":"219","author":"Goodenough","year":"1999","journal-title":"Novartis Foundation Symposium"},{"key":"10.1053\/plac.1999.0516_RF10","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1006\/excr.1998.4130","article-title":"Connexin transfection induces invasive properties in HeLa cells","volume":"243","author":"Graeber","year":"1998","journal-title":"Exp Cell Res"},{"key":"10.1053\/plac.1999.0516_RF11","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1053\/plac.1999.0406","article-title":"Characteristic growth of human choriocarcinoma xenografts in nude mice","volume":"20","author":"Gr\u00fcmmer","year":"1999","journal-title":"Placenta"},{"key":"10.1053\/plac.1999.0516_RF12","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1016\/S0021-9258(18)46052-8","article-title":"Four novel members of the connexin family of gap junction proteins. Molecular cloning, expression, and chromosome mapping","volume":"267","author":"Haefliger","year":"1992","journal-title":"J Biol Chem"},{"key":"10.1053\/plac.1999.0516_RF13","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1007\/s004240050162","article-title":"Properties of connexin40 gap junction channels endogenously expressed and exogenously overpressed in human choriocarcinoma cell lines","volume":"432","author":"Hellmann","year":"1996","journal-title":"Eur J Physiol"},{"key":"10.1053\/plac.1999.0516_RF14","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1006\/excr.1998.4332","article-title":"Transfection with different connexin genes alters growth and differentiation of human choriocarcinoma cells","volume":"246","author":"Hellmann","year":"1999","journal-title":"J Exp Cell Res"},{"key":"10.1053\/plac.1999.0516_RF15","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1095\/biolreprod60.5.1263","article-title":"Defects in the germ line and gonads of mice lacking connexin43","volume":"60","author":"Juneja","year":"1999","journal-title":"Biol Reprod"},{"key":"10.1053\/plac.1999.0516_RF16","first-page":"21","article-title":"Extravillous trophoblast in the human placenta","volume":"10","author":"Kaufmann","year":"1997","journal-title":"Trophoblast Research"},{"key":"10.1053\/plac.1999.0516_RF17","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1002\/(SICI)1097-0215(19980729)77:3<440::AID-IJC21>3.0.CO;2-A","article-title":"SV40 Tag transformation of the normal invasive trophoblast results in a premalignant phenotype. II. Changes in gap junctional intercellular communication","volume":"77","author":"Khoo","year":"1998","journal-title":"Int J Cancer"},{"key":"10.1053\/plac.1999.0516_RF18","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1210\/jcem-32-5-683","article-title":"Isolation of hormon-producing clonal lines of human choriocarcinoma","volume":"32","author":"Kohler","year":"1971","journal-title":"J Clin Endocrinol"},{"key":"10.1053\/plac.1999.0516_RF19","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1083\/jcb.113.2.437","article-title":"92-kD type IV collagenase mediates invasion of human cytotrophoblasts","volume":"113","author":"Librach","year":"1991","journal-title":"J Cell Biol"},{"key":"10.1053\/plac.1999.0516_RF20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/(SICI)1520-6408(1999)24:1\/2<1::AID-DVG1>3.0.CO;2-U","article-title":"Genes, gene knockouts, and mutations in the analysis of gap junctions","volume":"24","author":"Lo","year":"1999","journal-title":"Dev Gen"},{"key":"10.1053\/plac.1999.0516_RF21","first-page":"629","article-title":"Negative growth control of HeLa cells by connexin genes: connexin species specificity","volume":"55","author":"Mesnil","year":"1995","journal-title":"Cancer Res"},{"key":"10.1053\/plac.1999.0516_RF22","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/BF00315950","article-title":"Intercellular Junctions in the Full Term Human Placenta I. Syncytiotrophoblastic Layer","volume":"158","author":"Metz","year":"1979","journal-title":"Anat Embryol"},{"key":"10.1053\/plac.1999.0516_RF23","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/BF00315904","article-title":"Intercellular junctions in the full term human placenta II. Cytotrophoblast cells, intravillous stroma cells and blood vessels","volume":"158","author":"Metz","year":"1980","journal-title":"Anat Embryol"},{"key":"10.1053\/plac.1999.0516_RF24","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1177\/41.2.8093455","article-title":"Differentiation and proliferation patterns in human trophoblast revealed by c-erbB-2 oncogene product and EGF-R","volume":"41","author":"Muehlhauser","year":"1993","journal-title":"J Histochem Cytochem"},{"key":"10.1053\/plac.1999.0516_RF25","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1083\/jcb.103.1.123","article-title":"Molecular cloning of cDNA for rat liver gap junction protein","volume":"103","author":"Paul","year":"1986","journal-title":"J Cell Biol"},{"key":"10.1053\/plac.1999.0516_RF26","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1002\/(SICI)1097-0177(199602)205:2<172::AID-AJA8>3.0.CO;2-F","article-title":"Connexins and E-cadherin are differentially expressed during trophoblast invasion and placenta differentiation in the rat","volume":"205","author":"Reuss","year":"1996","journal-title":"Dev Dynam"},{"key":"10.1053\/plac.1999.0516_RF27","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0962-8924(99)01547-0","article-title":"Gap junctions: more roles and new structural data","volume":"9","author":"Simon","year":"1999","journal-title":"Trends in Cell Biology"},{"key":"10.1053\/plac.1999.0516_RF28","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/0092-8674(92)90503-5","article-title":"Invasion of the trophoblasts","volume":"71","author":"Strickland","year":"1992","journal-title":"Cell"},{"key":"10.1053\/plac.1999.0516_RF29","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/BF02110109","article-title":"Size and selectivity of gap junction channels formed from different connexins","volume":"28","author":"Veenstra","year":"1996","journal-title":"J Bioenergy Biomembranes"},{"key":"10.1053\/plac.1999.0516_RF30","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1159\/000299466","article-title":"The junctional pattern of human villous trophoblast. A freeze-fracture study","volume":"14","author":"de Vergiliis","year":"1982","journal-title":"Gynecol Obstet Invest"},{"key":"10.1053\/plac.1999.0516_RF31","series-title":"Progress in Cell Research, Vol. 3","first-page":"333","article-title":"The Mouse Connexin Gene Family","author":"Willecke","year":"1993"},{"key":"10.1053\/plac.1999.0516_RF32","series-title":"Embryonic Medicine and Therapy","first-page":"120","article-title":"Implantation and trophoblast differentiation","author":"Winterhager","year":"1997"},{"key":"10.1053\/plac.1999.0516_RF33","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1053\/plac.1999.0434","article-title":"Connexin expression patterns in human trophoblast cells during placental development","volume":"20","author":"Winterhager","year":"1999","journal-title":"Placenta"},{"key":"10.1053\/plac.1999.0516_RF34","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1161\/01.RES.83.12.1248","article-title":"Individual gap junction plaques contain multiple connexins in arterial endothelium","volume":"83","author":"Yeh","year":"1998","journal-title":"Circulation Res"},{"key":"10.1053\/plac.1999.0516_RF35","doi-asserted-by":"crossref","first-page":"3391","DOI":"10.1083\/jcb.109.6.3391","article-title":"Sequence and tissue distribution of a second protein of hepatic gap junctions, Cx26, as deduced from its cDNA","volume":"109","author":"Zhang","year":"1989","journal-title":"J Cell Biol"},{"key":"10.1053\/plac.1999.0516_RF36","doi-asserted-by":"crossref","first-page":"10218","DOI":"10.1073\/pnas.89.21.10218","article-title":"Growth retardation in glioma cells cocultured with cells overexpressing a gap junction protein","volume":"89","author":"Zhu","year":"1992","journal-title":"Proc Natl Acad Sci U S A"}],"container-title":["Placenta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400499905167?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143400499905167?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T19:47:09Z","timestamp":1758916029000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143400499905167"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,3]]},"references-count":36,"alternative-id":["S0143400499905167"],"URL":"https:\/\/doi.org\/10.1053\/plac.1999.0516","relation":{},"ISSN":["0143-4004"],"issn-type":[{"value":"0143-4004","type":"print"}],"subject":[],"published":{"date-parts":[[2000,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cell\u2013Cell-Communication during Placental Development and Possible Implications for Trophoblast Proliferation and Differentiation","name":"articletitle","label":"Article Title"},{"value":"Placenta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/plac.1999.0516","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2000 Harcourt Publishers Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}