{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T14:10:33Z","timestamp":1773756633606,"version":"3.50.1"},"reference-count":28,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,18]],"date-time":"2013-07-18T00:00:00Z","timestamp":1374105600000},"content-version":"vor","delay-in-days":4947,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","resmedjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Medicine"],"published-print":{"date-parts":[[2000,1]]},"DOI":"10.1053\/rmed.1999.0713","type":"journal-article","created":{"date-parts":[[2002,9,19]],"date-time":"2002-09-19T10:55:08Z","timestamp":1032432908000},"page":"44-50","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Antigen-induced airway inflammation and hyper-responsiveness does not enhance airway responses to a subsequent antigen challenge in rats"],"prefix":"10.1053","volume":"94","author":[{"given":"S.","family":"LABERGE","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"ROSSI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"X.X.","family":"YANG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.G.","family":"MARTIN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1053\/rmed.1999.0713_RF1","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/0091-6749(71)90080-7","article-title":"Immediate and late bronchial obstructive reactions to inhalation of house dust and protective effects of disodium cromoglycate and prednisolone","volume":"48","author":"Booij-Nord","year":"1971","journal-title":"J Allergy Clin Immunol"},{"key":"10.1053\/rmed.1999.0713_RF2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-2222.1973.tb01304.x","article-title":"Immunopathology of allergic lung disease","volume":"3","author":"Pepys","year":"1973","journal-title":"Clin Allergy"},{"key":"10.1053\/rmed.1999.0713_RF3","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/0091-6749(74)90067-0","article-title":"Late asthmatic responses induced by ragweed pollen allergen","volume":"54","author":"Robertson","year":"1974","journal-title":"J Allergy Clin Immunol"},{"key":"10.1053\/rmed.1999.0713_RF4","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1111\/j.1365-2222.1977.tb01481.x","article-title":"Allergen-induced increase in non-allergic bronchial reactivity","volume":"7","author":"Cockcroft","year":"1977","journal-title":"Clin Allergy"},{"key":"10.1053\/rmed.1999.0713_RF5","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/0091-6749(82)90038-0","article-title":"Allergen-induced increase in bronchial responsiveness to histamine: relationship to the late asthmatic response and change in airway caliber","volume":"70","author":"Cartier","year":"1982","journal-title":"J Allergy Clin Immunol"},{"key":"10.1053\/rmed.1999.0713_RF6","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1164\/ajrccm\/139.6.1383","article-title":"Leukocytes and mediators in bronchoalveolar lavage during allergen-induced late-phase asthmatic reactions","volume":"139","author":"Diaz","year":"1989","journal-title":"Am Rev Resp Dis"},{"key":"10.1053\/rmed.1999.0713_RF7","first-page":"373","article-title":"Bronchoalveolar eosinophilia during allergen-induced late asthmatic reactions","volume":"131","author":"DeMonchy","year":"1985","journal-title":"Am Rev Resp Dis"},{"key":"10.1053\/rmed.1999.0713_RF8","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0140-6736(83)90235-0","article-title":"Mechanism of perennial allergic asthma","volume":"2","author":"Cockcroft","year":"1983","journal-title":"Lancet"},{"key":"10.1053\/rmed.1999.0713_RF9","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1056\/NEJM199008233230802","article-title":"Exposure to house-dust mite allergen (Der P I) and the development of asthma in childhood: A prospective study","volume":"323","author":"Sporik","year":"1990","journal-title":"N Engl J Med"},{"key":"10.1053\/rmed.1999.0713_RF10","first-page":"433","article-title":"Local allergen challenge and bronchoalveolar lavage of allergic asthmatic lungs","volume":"135","author":"Metzger","year":"1987","journal-title":"Am Rev Respir Dis"},{"key":"10.1053\/rmed.1999.0713_RF11","doi-asserted-by":"crossref","first-page":"3710","DOI":"10.4049\/jimmunol.149.11.3710","article-title":"Comparison of airway and blood eosinophil function after in vivo antigen challenge","volume":"149","author":"Sedgwick","year":"1992","journal-title":"J Immunol"},{"key":"10.1053\/rmed.1999.0713_RF12","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1164\/ajrccm.149.2.8306028","article-title":"Immunophenotyping of eosinophils recovered from blood and BAL of allergic asthmatics","volume":"149","author":"Mengelers","year":"1994","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1053\/rmed.1999.0713_RF13","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1164\/ajrccm\/146.2.500","article-title":"Identification of T lymphocytes, macrophages, and activated eosinophils in the bronchial mucosa in intrinsic asthma","volume":"146","author":"Bentley","year":"1992","journal-title":"Am Rev Resp Dis"},{"key":"10.1053\/rmed.1999.0713_RF14","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1164\/ajrccm\/142.6_Pt_1.1407","article-title":"Identification of activated lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma","volume":"142","author":"Azzawi","year":"1990","journal-title":"Am Rev Resp Dis"},{"key":"10.1053\/rmed.1999.0713_RF15","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1056\/NEJM199010113231505","article-title":"Eosinophilic inflammation in asthma","volume":"323","author":"Bousquet","year":"1990","journal-title":"N Engl J Med"},{"key":"10.1053\/rmed.1999.0713_RF16","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1164\/ajrccm\/137.5.1033","article-title":"Late airway responses to antigen challenge in sensitized inbred rats","volume":"137","author":"Eidelman","year":"1988","journal-title":"Am Rev Resp Dis"},{"key":"10.1053\/rmed.1999.0713_RF17","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1164\/ajrccm\/147.4.967","article-title":"Inflammatory cell populations in the airways and parenchyma after antigen challenge in the rat","volume":"147","author":"Renzi","year":"1993","journal-title":"Am Rev Resp Dis"},{"key":"10.1053\/rmed.1999.0713_RF18","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/0091-6749(91)90253-K","article-title":"Characterization of allergen-induced bronchial hyperresponsiveness and airway inflammation in actively sensitized Brown\u2013Norway rats","volume":"88","author":"Elwood","year":"1991","journal-title":"J Allergy Clin Immunol"},{"key":"10.1053\/rmed.1999.0713_RF19","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1164\/ajrccm\/148.4_Pt_1.932","article-title":"Effect of dexamethasone on airway inflammation and responsiveness after antigen challenge of the rat","volume":"148","author":"Renzi","year":"1993","journal-title":"Am Rev Resp Dis"},{"key":"10.1053\/rmed.1999.0713_RF20","doi-asserted-by":"crossref","first-page":"2230","DOI":"10.1152\/jappl.1990.68.5.2230","article-title":"Quasi-static pressure-volume hysteresis in the canine respiratory system in vivo","volume":"68","author":"Shardonofsky","year":"1990","journal-title":"J Appl Physiol"},{"key":"10.1053\/rmed.1999.0713_RF21","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/0091-6749(92)90140-W","article-title":"The relationship between late asthmatic responses and antigen-specific immunoglobulin","volume":"90","author":"Waserman","year":"1992","journal-title":"J Allergy Clin Immunol"},{"key":"10.1053\/rmed.1999.0713_RF22","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1164\/ajrccm\/142.2.353","article-title":"Role of leukotriene D4 in the early and late pulmonary responses of rats to allergen challenge","volume":"142","author":"Sapienza","year":"1990","journal-title":"Am Rev Respir Dis"},{"key":"10.1053\/rmed.1999.0713_RF23","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1164\/ajrccm\/147.1.104","article-title":"Leukotrienes in bile during the early and the late airway responses after allergen challenge of sensitized rats","volume":"147","author":"Martin","year":"1993","journal-title":"Am Rev Respir Dis"},{"key":"10.1053\/rmed.1999.0713_RF24","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/0091-6749(89)90031-6","article-title":"Asthma and mast cell activation","volume":"83","author":"Kaliner","year":"1989","journal-title":"J Allergy Clin Immunol"},{"key":"10.1053\/rmed.1999.0713_RF25","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1172\/JCI118165","article-title":"Transfer if allergic airway responses with antigen-primed CD4+ but not CD8+ T cells in Brown Norway rats","volume":"96","author":"Watanabe","year":"1995","journal-title":"J Clin Invest"},{"key":"10.1053\/rmed.1999.0713_RF26","unstructured":"Sheth, K, K, Lemanske, R, F, The early and late asthmatic responses to allergen, Busse, W, WHolgate, S, T, Asthma and Rhinitis, Blackwell Scientific Publications, Inc. 1995, 946, 960"},{"key":"10.1053\/rmed.1999.0713_RF27","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1164\/ajrccm\/142.2.434","article-title":"Mucosal inflammation in asthma","volume":"142","author":"Djukanovic","year":"1990","journal-title":"Am Rev Resp Dis"},{"key":"10.1053\/rmed.1999.0713_RF28","doi-asserted-by":"crossref","first-page":"S20","DOI":"10.1164\/ajrccm\/147.6_Pt_2.S20","article-title":"Mechanism of airway inflammation in asthma","volume":"147","author":"Busse","year":"1993","journal-title":"Am Rev Resp Dis"}],"container-title":["Respiratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611199907138?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611199907138?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T10:01:57Z","timestamp":1760608917000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0954611199907138"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,1]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2000,1]]}},"alternative-id":["S0954611199907138"],"URL":"https:\/\/doi.org\/10.1053\/rmed.1999.0713","relation":{},"ISSN":["0954-6111"],"issn-type":[{"value":"0954-6111","type":"print"}],"subject":[],"published":{"date-parts":[[2000,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antigen-induced airway inflammation and hyper-responsiveness does not enhance airway responses to a subsequent antigen challenge in rats","name":"articletitle","label":"Article Title"},{"value":"Respiratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/rmed.1999.0713","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2000 Harcourt Publishers Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}