{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T06:16:15Z","timestamp":1770358575016,"version":"3.49.0"},"reference-count":32,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2000,3,1]],"date-time":"2000-03-01T00:00:00Z","timestamp":951868800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2000,3,1]],"date-time":"2000-03-01T00:00:00Z","timestamp":951868800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,18]],"date-time":"2013-07-18T00:00:00Z","timestamp":1374105600000},"content-version":"vor","delay-in-days":4887,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","resmedjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Medicine"],"published-print":{"date-parts":[[2000,3]]},"DOI":"10.1053\/rmed.1999.0735","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T07:24:42Z","timestamp":1027668282000},"page":"264-272","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"title":["The expression of lymphocyte surface antigens in bronchial biopsies, bronchoalveolar lavage cells and blood cells in healthy smoking and never-smoking men, 60 years old"],"prefix":"10.1053","volume":"94","author":[{"given":"A","family":"EKBERG-JANSSON","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"ANDERSSON","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"ARV\u00c5","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O","family":"NILSSON","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.G","family":"LFDAHL","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1053\/rmed.1999.0735_RF1","series-title":"The natural history of chronic bronchitis and emphysema","author":"Fletcher","year":"1976"},{"key":"10.1053\/rmed.1999.0735_RF2","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1136\/bmj.1.6077.1645","article-title":"The natural history of chronic airflow obstruction","volume":"1","author":"Fletcher","year":"1977","journal-title":"Br Med J"},{"key":"10.1053\/rmed.1999.0735_RF3","first-page":"113","article-title":"Cost development of obstructive airway disease in Sweden","volume":"6","author":"L\u00f6fdahl","year":"1996","journal-title":"Eur Respir Rev"},{"key":"10.1053\/rmed.1999.0735_RF4","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1164\/ajrccm\/147.2.301","article-title":"Activated T-lymphocytes and macrophages in bronchial mucosa of subjects with chronic bronchitis","volume":"147","author":"Saetta","year":"1993","journal-title":"Am Rev Respir Dis"},{"key":"10.1053\/rmed.1999.0735_RF5","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1183\/09031936.94.07030437","article-title":"T-cell and macrophage subsets in the bronchial wall of clinically healthy subjects","volume":"7","author":"Power","year":"1994","journal-title":"Eur Respir J"},{"key":"10.1053\/rmed.1999.0735_RF6","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1164\/ajrccm\/140.3.737","article-title":"Intraepithelial T-lymphocyte subsets in the airways of normal subjects and patients with chronic bronchitis","volume":"140","author":"Fournier","year":"1989","journal-title":"Am Rev Respir Dis"},{"key":"10.1053\/rmed.1999.0735_RF7","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/S0954-6111(99)90156-7","article-title":"A comparison of the expression of lymphocyte activation markers in blood, bronchial biopsies and bronchoalveolar lavage. Evidence for an enrichment of activated T lymphocytes in the bronchoalveolar space","volume":"93","author":"Ekberg-Jansson","year":"1999","journal-title":"Respir Med"},{"key":"10.1053\/rmed.1999.0735_RF8","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1164\/ajrccm.153.2.8564109","article-title":"Airflow limitation in chronic bronchitis is associated with T-lymphocyte and macrophage infiltration of the bronchial mucosa","volume":"153","author":"Di Stefano","year":"1996","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1053\/rmed.1999.0735_RF9","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1164\/ajrccm.155.3.9117016","article-title":"Inflammation in bronchial biopsies of subjects with chronic bronchitis: Inverse relationship of CD8+ T lymphocytes with FEV1","volume":"155","author":"O'Shaughnessy","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1053\/rmed.1999.0735_RF10","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1378\/chest.90.1.39","article-title":"Alterations in immunoregulatory T-cell subsets in cigarette smokers","volume":"90","author":"Costabel","year":"1986","journal-title":"Chest"},{"key":"10.1053\/rmed.1999.0735_RF11","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/PL00007585","article-title":"Lymphocyte subsets in peripheral blood and smoking habits","volume":"175","author":"Schaberg","year":"1997","journal-title":"Lung"},{"key":"10.1053\/rmed.1999.0735_RF12","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1159\/000196097","article-title":"Local immune components in chronic obstructive pulmonary disease","volume":"1","author":"Costabel","year":"1992","journal-title":"Respiration"},{"key":"10.1053\/rmed.1999.0735_RF13","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1183\/09031936.98.11010046","article-title":"Immunological findings in blood and bronchoalveolar lavage fluid in chronic bronchitis patients with recurrent infectious exacerbations","volume":"11","author":"Qvarfordt","year":"1998","journal-title":"Eur Respir J"},{"key":"10.1053\/rmed.1999.0735_RF14","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1136\/bmj.307.6912.1102","article-title":"Stressful life events, social support, and mortality in men born in 1933","volume":"307","author":"Rosengren","year":"1993","journal-title":"Br Med J"},{"key":"10.1053\/rmed.1999.0735_RF15","first-page":"320","article-title":"Measurement of closing volume with the single breath nitrogen method","volume":"55","author":"Oxh\u00f6j","year":"1974","journal-title":"Scand J Respir Dis"},{"key":"10.1053\/rmed.1999.0735_RF16","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1183\/09041950.005s1693","article-title":"Lung volumes and forced ventilatory flows. Official statment of the European Respiratory Society","volume":"6","author":"Quanjer","year":"1993","journal-title":"Eur Respir J"},{"key":"10.1053\/rmed.1999.0735_RF17","first-page":"7","article-title":"Single-breath pulmonary diffusing capacity. Reference values and application in connective tissue diseases avd in various lung diseases","author":"Salorinne","year":"1976","journal-title":"Scand J Resp Dis"},{"key":"10.1053\/rmed.1999.0735_RF18","first-page":"296","article-title":"The single-breath N2-test and spirometry in healthy non-smoking males","volume":"65","author":"Sixt","year":"1984","journal-title":"Eur J Respir Dis"},{"key":"10.1053\/rmed.1999.0735_RF19","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1378\/chest.104.1.32","article-title":"Expression of lymphocyte activation surface antigens in bronchoalveolar lavage and periferal blood cells from young healthy subjects","volume":"104","author":"Ancochea","year":"1993","journal-title":"Chest"},{"key":"10.1053\/rmed.1999.0735_RF20","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0954-6111(95)90189-2","article-title":"Alveolar lavage fluid (ALF) of normal volunteer subjects: cytologic, immunocytochemical, and biochemical reference values","volume":"89","author":"Sutinen","year":"1995","journal-title":"Respir Med"},{"key":"10.1053\/rmed.1999.0735_RF21","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1164\/ajrccm.152.5.7582312","article-title":"Alveolar inflammation and its relation to emphysema in smokers","volume":"152","author":"Finkelstein","year":"1995","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1053\/rmed.1999.0735_RF22","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1164\/ajrccm.157.3.9709027","article-title":"CD8+ T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease","volume":"157","author":"Saetta","year":"1998","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1053\/rmed.1999.0735_RF23","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1002\/art.1780360506","article-title":"Increased percentage of CD3+, CD57+ lymphocytes in patients with rheumatoid arthritis. Correlation with duration of disease","volume":"36","author":"Dupuy d Angeac","year":"1993","journal-title":"Arthritis Rheum"},{"key":"10.1053\/rmed.1999.0735_RF24","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1164\/ajrccm.149.4.7511468","article-title":"Alveolar CD8+CD57+ lymphocytes in human immunodeficiency virus infection produce an inhibitor of cytotoxic functions","volume":"149","author":"Sadat-Sowti","year":"1994","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1053\/rmed.1999.0735_RF25","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.1365-2249.1993.tb03447.x","article-title":"Subsets of CD8+, CD57+ cells in normal, healthy individuals: correlations with human cytomegalovirus (HCMV) carrier status, phenotyic and functional analyses","volume":"94","author":"Wang","year":"1993","journal-title":"Clin Exper Immunol"},{"key":"10.1053\/rmed.1999.0735_RF26","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1093\/intimm\/10.3.311","article-title":"CD8hi+CD57+ T lymphocytes are enriched in antigen-specific T cells capable of down-modulating cytotoxic activity","volume":"10","author":"Mollet","year":"1998","journal-title":"Int Immunol"},{"key":"10.1053\/rmed.1999.0735_RF27","first-page":"69","article-title":"The role of CD8+, CD57+ cells in human cytomegalovirus and other viral infections","volume":"99","author":"Wang","year":"1995","journal-title":"Scand J Infect Dis Suppl"},{"key":"10.1053\/rmed.1999.0735_RF28","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1378\/chest.82.5.526","article-title":"Reversible alterations in immunoregulatory T cells in smoking. Analysis by monoclonal antibodies and flow cytometry","volume":"82","author":"Miller","year":"1982","journal-title":"Chest"},{"key":"10.1053\/rmed.1999.0735_RF29","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1006\/bbrc.1997.7444","article-title":"The role of CD8+ Th2 lymphocytes in the development of smoking-related lung damage","volume":"239","author":"Mattoli","year":"1997","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1053\/rmed.1999.0735_RF30","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1084\/jem.181.1.5","article-title":"The functional role of CD8+ T helper type 2 cells","volume":"181","author":"Seder","year":"1995","journal-title":"J Exp Med"},{"key":"10.1053\/rmed.1999.0735_RF31","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1165\/ajrcmb.16.4.9115759","article-title":"A novel role for murine IL-4 in vivo: induction of MUC5AC gene expression and mucin hypersecretion","volume":"16","author":"Temann","year":"1997","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1053\/rmed.1999.0735_RF32","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1164\/ajrccm.150.6.7952628","article-title":"Airway eosinophilia in chronic bronchitis during exacerbations","volume":"150","author":"Saetta","year":"1994","journal-title":"Am J Respir Crit Care Med"}],"container-title":["Respiratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611199907357?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611199907357?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T10:01:58Z","timestamp":1760608918000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0954611199907357"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,3]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2000,3]]}},"alternative-id":["S0954611199907357"],"URL":"https:\/\/doi.org\/10.1053\/rmed.1999.0735","relation":{},"ISSN":["0954-6111"],"issn-type":[{"value":"0954-6111","type":"print"}],"subject":[],"published":{"date-parts":[[2000,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The expression of lymphocyte surface antigens in bronchial biopsies, bronchoalveolar lavage cells and blood cells in healthy smoking and never-smoking men, 60 years old","name":"articletitle","label":"Article Title"},{"value":"Respiratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/rmed.1999.0735","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2000 Harcourt Publishers Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}