{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T18:02:51Z","timestamp":1790791371381,"version":"4.1.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2002,10,1]],"date-time":"2002-10-01T00:00:00Z","timestamp":1033430400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Seminars in Perinatology"],"published-print":{"date-parts":[[2002,10]]},"DOI":"10.1053\/sper.2002.36267","type":"journal-article","created":{"date-parts":[[2006,5,22]],"date-time":"2006-05-22T13:06:25Z","timestamp":1148303185000},"page":"340-345","source":"Crossref","is-referenced-by-count":94,"title":["Hospital-acquired infections in the neonatal intensive care unit-Klebsiella pneumoniae"],"prefix":"10.1053","volume":"26","author":[{"given":"Archana","family":"Gupta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/sper.2002.36267_bib1","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/0195-6701(93)90013-P","article-title":"Klebsiella and the neonate","volume":"23","author":"Hart","year":"1993","journal-title":"J Hosp Infect"},{"key":"10.1053\/sper.2002.36267_bib2","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1099\/0022-1317-49-2-115","article-title":"Expression of putative virulence factors by clinical isolates of Klebsiella planticola","volume":"49","author":"Podschun","year":"2000","journal-title":"J Med Microbiol"},{"key":"10.1053\/sper.2002.36267_bib3","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1542\/peds.98.3.357","article-title":"Hospital-acquired infections among neonates in high-risk nurseries in the United States","volume":"98","author":"Gaynes","year":"1996","journal-title":"Pediatrics"},{"key":"10.1053\/sper.2002.36267_bib4","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0022-3476(96)70191-9","article-title":"Late-onset sepsis in very low birth weight neonates: A report from the NICHD Neonatal Research Network","volume":"129","author":"Stoll","year":"1996","journal-title":"J Pediatr"},{"key":"10.1053\/sper.2002.36267_bib5","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1067\/mpd.2001.119442","article-title":"Prevelance of hospital-acquired infections in the neonatal intensive care unit patients: Results from the first national point-prevalence survey","volume":"139","author":"Sohn","year":"2001","journal-title":"J Pediatr"},{"key":"10.1053\/sper.2002.36267_bib6","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1128\/AAC.33.8.1131","article-title":"Extended-spectrum \u03b2-lactamases","volume":"33","author":"Philippon","year":"1989","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1053\/sper.2002.36267_bib7","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1093\/clinids\/21.4.915","article-title":"Molecular epidemiology of an SHV-5 Extended-spectrum \u03b2-lactamase in Enterobacteriaceae isolated from infants in a neonatal intensive care unit","volume":"21","author":"Venezia","year":"1995","journal-title":"Clin Infect Dis"},{"key":"10.1053\/sper.2002.36267_bib8","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1086\/319757","article-title":"Extended-spectrum \u03b2-lactamase-producing Escherichia coli and Klebsiella pneumoniae. Risk factors for infection and impact of resistance on outcomes","volume":"32","author":"Lautenbach","year":"2001","journal-title":"Clin Infect Dis"},{"key":"10.1053\/sper.2002.36267_bib9","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1128\/AAC.42.1.53","article-title":"Epidemiology and successful control of a large outbreak due to Klebsiella pneumoniae producting extended \u03b2-lactamases","volume":"42","author":"Pena","year":"1998","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1053\/sper.2002.36267_bib10","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1053\/jhin.2001.1066","article-title":"A simultaneous outbreak on a neonatal unit of two strains of multiply antibiotic resistant Klebsiella pneumoniae controllable only by ward closure","volume":"49","author":"Macrae","year":"2001","journal-title":"J Hosp Infec"},{"key":"10.1053\/sper.2002.36267_bib11","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/0002-9343(86)90480-8","article-title":"Review of epidemic aminoglycoside resistance worldwide","volume":"80","author":"Mayer","year":"1986","journal-title":"Am J Med"},{"key":"10.1053\/sper.2002.36267_bib12","doi-asserted-by":"crossref","first-page":"S45","DOI":"10.1093\/infdis\/131.Supplement.S45","article-title":"Hospitalacquired infections caused by gentamicin-resistant streptomycin-sensitive Klebsiella","volume":"131","author":"Noreiga","year":"1975","journal-title":"J Infect Dis"},{"key":"10.1053\/sper.2002.36267_bib13","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1093\/jac\/36.suppl_A.19","article-title":"Extended-spectrum plasmid mediated \u03b2-lactamases","volume":"36","author":"Sirot","year":"1995","journal-title":"J Antimicrob Chemother"},{"key":"10.1053\/sper.2002.36267_bib14","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1093\/infdis\/170.6.1622","article-title":"The national hospitalacquired infection surveillance system. Ceftazidime resistance among selected hospital-acquired gram-negative bacilli in the United States","volume":"170","author":"Burwen","year":"1994","journal-title":"J Infect Dis"},{"key":"10.1053\/sper.2002.36267_bib15","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/S0272-5231(05)70143-X","article-title":"Antimicrobial resistance in intensive care units","volume":"20","author":"Fredkin","year":"1999","journal-title":"Clin Chest Med"},{"key":"10.1053\/sper.2002.36267_bib16","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1086\/514644","article-title":"Editorial response: Epidemiology of extendedspectrum \u03b2-lactamases","volume":"27","author":"Jacoby","year":"1998","journal-title":"Clin Infect Dis"},{"key":"10.1053\/sper.2002.36267_bib17","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1093\/infdis\/174.3.529","article-title":"Ceftazidimeresistant Klebsiella pneumoniae and Escherichia coli blood stream infection: A case-control and molecular epidemiology investigation","volume":"174","author":"Schiappa","year":"1996","journal-title":"J Infect Dis"},{"key":"10.1053\/sper.2002.36267_bib18","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1086\/514643","article-title":"Spread of extended-spectrum \u03b2-lactamase producing Klebsiella pneumoniae Are \u03b2-lactamase inhibitors of therapeutic value?","volume":"27","author":"Piroth","year":"1998","journal-title":"Clin Infect Dis"},{"key":"10.1053\/sper.2002.36267_bib19","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1592\/phco.21.11.920.34529","article-title":"Extended-spectrum \u03b2-lactamases: Epidemiology, detection and treatment","volume":"21","author":"Nathisuwan","year":"2001","journal-title":"Pharmacotherapy"},{"key":"10.1053\/sper.2002.36267_bib20","series-title":"Approved standard M-100-S10: performance standards for antimicrobial susceptibility testing","author":"Standards","year":"2000"},{"key":"10.1053\/sper.2002.36267_bib21","series-title":"Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. Approved standard M7-A5","author":"(NCCLS) NCfCLS","year":"2000"},{"key":"10.1053\/sper.2002.36267_bib22","series-title":"Principles and Practices of Clinical Bacteriology","first-page":"413","article-title":"Klebsiella, Citrobacter, Enterobacter and Serratia","author":"Hart","year":"1997"},{"key":"10.1053\/sper.2002.36267_bib23","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1128\/CMR.11.4.589","article-title":"Klebsiella spp. as hospital-acquired pathogens: Epidemiology, taxonomy, typing methods and pathogenecity factors","volume":"11","author":"Podschun","year":"1998","journal-title":"Clin Micro Review"},{"key":"10.1053\/sper.2002.36267_bib24","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1128\/IAI.59.5.1673-1682.1991","article-title":"Lectinophagocytosis of encapsulated Klebsiella pneumoniae mediated by surface lectins of guinea pig alveolar macrophages and human monocyte derived macrophages","volume":"59","author":"Athamna","year":"1991","journal-title":"Infect Immun"},{"key":"10.1053\/sper.2002.36267_bib25","series-title":"Virulence mechanics of bacterial pathogens","first-page":"121","article-title":"High affinity iron uptake systems and bacterial virulence","author":"Griffiths","year":"1988"},{"key":"10.1053\/sper.2002.36267_bib26","series-title":"Presented at the 12th Annual meeting of the Society for Healthcare Epidemiology of America","article-title":"Extended-spectrum \u03b2-lactamase producing Klebsiella pneumoniae outbreak in a neonatal intensive care unit","author":"Gupta","year":"2002"},{"key":"10.1053\/sper.2002.36267_bib27","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1093\/jac\/39.6.737","article-title":"Rarity of transferable \u03b2-lactamase production by Klebsiella species","volume":"39","author":"Leung","year":"1997","journal-title":"J Antimicrob Chemother"},{"key":"10.1053\/sper.2002.36267_bib28","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1128\/AAC.34.11.2193","article-title":"Outbreak of ceftazidime resistance caused by extended spectrum \u03b2-lactamase at a Massachusetts chronic-care facility","volume":"34","author":"Rice","year":"1990","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1053\/sper.2002.36267_bib29","doi-asserted-by":"crossref","first-page":"353","DOI":"10.7326\/0003-4819-119-5-199309010-00001","article-title":"Hospital-acquired outbreak of Klebsiella infection resistant to third-generation cephalosporins","volume":"119","author":"Meyer","year":"1993","journal-title":"Ann Int Med"},{"key":"10.1053\/sper.2002.36267_bib30","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1128\/JCM.35.8.2061-2067.1997","article-title":"Detection and clinical significance of extended-spectrum \u03b2-lactamase in a tertiary care medical center","volume":"35","author":"Emery","year":"1999","journal-title":"J Clin Microbiol"},{"key":"10.1053\/sper.2002.36267_bib31","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1128\/AAC.36.9.1991","article-title":"Outbreak of ceftazidime resistance due to a novel extended-spectrum \u03b2-lactamase in isolates from cancer patients","volume":"36","author":"Naumovski","year":"1992","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1053\/sper.2002.36267_bib32","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1128\/AAC.38.4.767","article-title":"Comparative activities of clavulanic acid, sulbactam and tazobactam against clinically important \u03b2-lactamase","volume":"38","author":"Payne","year":"1994","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1053\/sper.2002.36267_bib33","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1128\/AAC.34.5.858","article-title":"Activities of \u03b2-lactam antibiotics against Escherichia coli strains producing extended-spectrum \u03b2-lactamases","volume":"34","author":"Jacoby","year":"1990","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1053\/sper.2002.36267_bib34","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1055\/s-2007-993898","article-title":"Piperacillin\/tazobactam in the treatment of Klebsiella pneumoniae infection in neonates","volume":"15","author":"Pillay","year":"1998","journal-title":"Am J Perinatol"},{"key":"10.1053\/sper.2002.36267_bib35","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1128\/AAC.36.9.1883","article-title":"Piperacillin, tazobactam, and gentamicin alone or combined in an endocarditis model of infection by TEM-3-producing strain of Klebsiella pneumoniae or its susceptible variant","volume":"36","author":"Mentec","year":"1992","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1053\/sper.2002.36267_bib36","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1128\/JCM.34.2.358-363.1996","article-title":"Hospital outbreak of Klebsiella pneumoniae resistant to broad-spectrum cephalosporins and \u03b2-lactam-\u03b2-lactamase inhibitor combinations by hyperproduction of SHV-5 \u03b2-lactamase","volume":"34","author":"French","year":"1996","journal-title":"J Clin Microbiol"},{"key":"10.1053\/sper.2002.36267_bib37","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1128\/AAC.38.2.195","article-title":"Different ratios of the piperacillin\/tazobactam combination for treatment of experimental meningitis due to Klebsiella pneumoniae producing the TEM-3 extended-spectrum \u03b2-lactamase","volume":"38","author":"Leleu","year":"1994","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1053\/sper.2002.36267_bib38","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1128\/AAC.35.6.1243","article-title":"Efficacy of different \u03b2-lactams against an extended-spectrum \u03b2-lactamase-producing Klebsiellae pneumoniae strain in the rat intra-abdominal abscess model","volume":"35","author":"Rice","year":"1991","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1053\/sper.2002.36267_bib39","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1515\/jpme.1996.24.3.287","article-title":"Growth and development in preterm infants receiving fluoroquinolones","volume":"24","author":"Martell","year":"1996","journal-title":"J Perinat Med"},{"key":"10.1053\/sper.2002.36267_bib40","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1086\/313719","article-title":"Epidemiology of ciprofloxacin resistance and its relationship to extended-spectrum \u03b2-lactamase production in Klebsiella pneumoniae isolates causing bacteremia","volume":"30","author":"Paterson","year":"2000","journal-title":"Clin Infect Dis"},{"key":"10.1053\/sper.2002.36267_bib41","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1191\/096032799678840237","article-title":"The comparative arthropathy of fluoroquinolones in dogs","volume":"18","author":"Takizawa","year":"1999","journal-title":"Hum Exp Toxicol"},{"key":"10.1053\/sper.2002.36267_bib42","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1177\/030006059802600604","article-title":"Oral ciprofloxacin in the treatment of Pseudomonas exacerbations of paediatric cystic fibrosis: Clinical efficacy and safety evaluation using magnetic resonance image scanning","volume":"26","author":"Redmond","year":"1998","journal-title":"J Int Med Res"},{"key":"10.1053\/sper.2002.36267_bib43","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1542\/peds.101.4.658","article-title":"Single-dose and steady-state pharmacokinetics of a new oral suspension of ciprofloxacin in children","volume":"101","author":"Peltola","year":"1998","journal-title":"Pediatrics"},{"key":"10.1053\/sper.2002.36267_bib44","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1086\/501787","article-title":"Association of antibiotic utilization measures and control of multipledrug resistance in Klebsiella pneumoniae","volume":"21","author":"Patterson","year":"2000","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1053\/sper.2002.36267_bib45","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/0196-6553(89)90003-5","article-title":"Bacterial carriage by artificial versus natural nails","volume":"17","author":"Pottinger","year":"1989","journal-title":"Am J Infect Control"},{"key":"10.1053\/sper.2002.36267_bib46","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1097\/00006199-199801000-00010","article-title":"Impact of a 5-minute scrub on the microbial flora found on artificial, polished, or natural fingernails of operating room personnel","volume":"47","author":"Edel","year":"1998","journal-title":"Nur Res"},{"key":"10.1053\/sper.2002.36267_bib47","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/S0001-2092(07)63328-6","article-title":"Bacterial carriage on the fingernails of OR Nurses","volume":"60","author":"Wynd","year":"1994","journal-title":"AORN J"},{"key":"10.1053\/sper.2002.36267_bib48","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1086\/501794","article-title":"Pathogenic organisms associated with artificial fingernails","volume":"21","author":"Hedderwick","year":"2000","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1053\/sper.2002.36267_bib49","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1067\/mic.2002.122102","article-title":"Banning artificial nails from health care settings","volume":"30","author":"Saiman","year":"2002","journal-title":"Am J Infect Control"},{"key":"10.1053\/sper.2002.36267_bib50","unstructured":"Boyce JM, Pittet D: The HICPAC\/SHEA\/APIC\/IDSA hand hygiene task force; and HICPAC hand hygiene guideline for healthcare settings (in press)."}],"container-title":["Seminars in Perinatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0146000502800453?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0146000502800453?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,7]],"date-time":"2023-05-07T13:29:34Z","timestamp":1683466174000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0146000502800453"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,10]]},"references-count":50,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2002,10]]}},"alternative-id":["S0146000502800453"],"URL":"https:\/\/doi.org\/10.1053\/sper.2002.36267","relation":{},"ISSN":["0146-0005"],"issn-type":[{"value":"0146-0005","type":"print"}],"subject":[],"published":{"date-parts":[[2002,10]]}}}