{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T11:52:43Z","timestamp":1790682763854,"version":"4.1.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[1999,6,1]],"date-time":"1999-06-01T00:00:00Z","timestamp":928195200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Drug Resistance Updates"],"published-print":{"date-parts":[[1999,6]]},"DOI":"10.1054\/drup.1999.0088","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T11:36:10Z","timestamp":1027683370000},"page":"148-152","source":"Crossref","is-referenced-by-count":13,"title":["Limitations of antifungal agents in the treatment of Candida vaginitis: future challenges"],"prefix":"10.1054","volume":"2","author":[{"given":"Jack D.","family":"Sobel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1054\/drup.1999.0088_RF1","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1001\/jama.1984.03340290034016","article-title":"Establishing the cause of symptoms in women in a family practice","volume":"251","author":"Berg","year":"1984","journal-title":"J Am Med Aassoc"},{"key":"10.1054\/drup.1999.0088_RF2","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.2105\/AJPH.85.8_Pt_1.1146","article-title":"Epidemiology of vulvovaginal candidiasis among university students","volume":"85","author":"Geiger","year":"1995","journal-title":"Am J Public Health"},{"key":"10.1054\/drup.1999.0088_RF3","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1097\/00001648-199603000-00013","article-title":"Risk factors in vulvovaginal candidiasis: a case-control study among college students","author":"Geiger","year":"1996","journal-title":"Epidemiol"},{"key":"10.1054\/drup.1999.0088_RF4","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1136\/pgmj.55.647.645","article-title":"Candida vaginitis","volume":"55","author":"Hurley","year":"1979","journal-title":"Postgrad Med J"},{"key":"10.1054\/drup.1999.0088_RF5","series-title":"Candida and candidosis. A review and bibliography, 2nd edition","article-title":"Candidiasis of the genitalia","author":"Odds","year":"1988"},{"key":"10.1054\/drup.1999.0088_RF6","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1002\/j.1552-4604.1992.tb03833.x","article-title":"Evolving pathogens in vulvovaginal candidiasis: implications for patient care","volume":"32","author":"Horowitz","year":"1992","journal-title":"J Clin Pharmacol"},{"key":"10.1054\/drup.1999.0088_RF7","doi-asserted-by":"crossref","first-page":"329","DOI":"10.2105\/AJPH.80.3.329","article-title":"Epidemiology of vulvovaginal candidiasis: risk factors","volume":"80","author":"Foxman","year":"1990","journal-title":"Am J Public Health"},{"key":"10.1054\/drup.1999.0088_RF8","first-page":"595","article-title":"Women\u2019s use of over-the-counter antifungal pharmaceutical products for gynecologic symptoms","volume":"42","author":"Ferris","year":"1996","journal-title":"J Fam Pract"},{"key":"10.1054\/drup.1999.0088_RF9","doi-asserted-by":"crossref","unstructured":"Reef, S. Levine, W. C. McNeil, M. M. Treatment options for vulvovaginal candidiasis. Background paper for development of 1993 STD treatment recommendations. Clin Infect Dis 1995; 20 (Suppl): 580\u2013590.","DOI":"10.1093\/clinids\/20.Supplement_1.S80"},{"key":"10.1054\/drup.1999.0088_RF10","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/0002-9378(95)91490-0","article-title":"Single oral dose fluconazole compared with conventional topical therapy of Candida vaginitis","volume":"172","author":"Sobel","year":"1995","journal-title":"Am J Obstet Gynecol"},{"key":"10.1054\/drup.1999.0088_RF11","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0002-9378(98)80001-X","article-title":"Vulvovaginal candidiasis: epidemiologic, diagnostic and therapeutic considerations","volume":"178","author":"Sobel","year":"1998","journal-title":"Am J Obstet Gynecol"},{"key":"10.1054\/drup.1999.0088_RF12","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1128\/AAC.34.5.909","article-title":"Fluconazole levels in plasma and vaginal secretions of patients with the 150 mg single dose and rate of eradication of infections in vaginal candidiasis","volume":"34","author":"Houang","year":"1990","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1054\/drup.1999.0088_RF13","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/S0002-9378(85)80003-X","article-title":"Epidemiology and pathogenesis of recurrent vulvovaginal candidiasis","volume":"152","author":"Sobel","year":"1985","journal-title":"Am J Obstet Gynecol"},{"key":"10.1054\/drup.1999.0088_RF14","first-page":"1566","article-title":"Karyotyping of C.","volume":"170","author":"Vazquez","year":"1994","journal-title":"albicans"},{"key":"10.1054\/drup.1999.0088_RF15","first-page":"343","article-title":"Recurrent vulvovaginal candidiasis: results of a cohort study of sexual transmission and intestinal reservoir","volume":"37","author":"Carrata","year":"1992","journal-title":"J Reproduct Med"},{"key":"10.1054\/drup.1999.0088_RF16","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1128\/CMR.9.3.335","article-title":"Immunopathogenesis of recurrent vulvovaginal candidiasis","volume":"9","author":"Fidel","year":"1996","journal-title":"Clin Microbiol Rev"},{"key":"10.1054\/drup.1999.0088_RF17","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1086\/517314","article-title":"Association of recurrent vaginal candidiasis and secretory ABO+ Lewis phenotype","volume":"176","author":"Chaim","year":"1997","journal-title":"J Infect Dis"},{"key":"10.1054\/drup.1999.0088_RF18","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1128\/JCM.34.10.2497-2499.1996","article-title":"Vaginal microbiology of women with recurrent vulvovaginal candidiasis","volume":"34","author":"Sobel","year":"1996","journal-title":"J Clin Micro"},{"key":"10.1054\/drup.1999.0088_RF19","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/S0016-5085(84)80021-9","article-title":"Hepatic injury associated with ketoconazole therapy: analysis of 33 cases","volume":"22","author":"Lewis","year":"1984","journal-title":"Gastroenterology"},{"key":"10.1054\/drup.1999.0088_RF20","first-page":"343","article-title":"Recurrent vaginal candidiasis: results of a cohort study of sexual transmission and intestinal reservoir","volume":"37","author":"Spinillo","year":"1992","journal-title":"J Reproduct Med"},{"key":"10.1054\/drup.1999.0088_RF21","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1086\/514979","article-title":"Mucosal candidal colonization and candidiasis in women with or at risk for HIV infection","volume":"27","author":"Schuman","year":"1998","journal-title":"Clin Infect Dis"},{"key":"10.1054\/drup.1999.0088_RF22","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1086\/514746","article-title":"Evolution of vaginal Candida species recovered from HIV-infected women receiving fluconazole prophylaxis: the emergence of Candida glabrata ?","volume":"28","author":"Vazquez","year":"1999","journal-title":"Clin Infect Dis"},{"key":"10.1054\/drup.1999.0088_RF23","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1439-0507.1998.tb00594.x","article-title":"Vulvovaginitis due to Candida glabrata vaginitis: an emerging problem","volume":"41 (Suppl 2)","author":"Sobel","year":"1998","journal-title":"Mycoses"},{"key":"10.1054\/drup.1999.0088_RF24","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1093\/clind\/24.4.649","article-title":"Treatment of Candida glabrata vaginitis: A retrospective review of boric acid therapy","volume":"24","author":"Sobel","year":"1997","journal-title":"Clin Infect Dis"},{"key":"10.1054\/drup.1999.0088_RF25","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1093\/clinids\/22.4.726","article-title":"Symptomatic vulvovaginitis due to resistant Candida albicans in a female who was not infected with human immunodeficiency virus","volume":"22","author":"Sobel","year":"1996","journal-title":"Clin Infect Dis"}],"container-title":["Drug Resistance Updates"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1368764699900882?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1368764699900882?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,16]],"date-time":"2021-05-16T07:23:53Z","timestamp":1621149833000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1368764699900882"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,6]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1999,6]]}},"alternative-id":["S1368764699900882"],"URL":"https:\/\/doi.org\/10.1054\/drup.1999.0088","relation":{},"ISSN":["1368-7646"],"issn-type":[{"value":"1368-7646","type":"print"}],"subject":[],"published":{"date-parts":[[1999,6]]}}}