{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T18:46:30Z","timestamp":1762541190658},"reference-count":29,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2000,7,1]],"date-time":"2000-07-01T00:00:00Z","timestamp":962409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Clinical Neuroscience"],"published-print":{"date-parts":[[2000,7]]},"DOI":"10.1054\/jocn.1999.0666","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T07:35:14Z","timestamp":1027668914000},"page":"320-324","source":"Crossref","is-referenced-by-count":6,"title":["The effect of pinealectomy on immune parameters in different age groups in rats: results of the weekly alteration of the zinc level and the effect of melatonin administration on wound healing"],"prefix":"10.1054","volume":"7","author":[{"given":"Etem","family":"Beskonakli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sel\u00e7uk","family":"Palaoglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nurten","family":"Renda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sezer","family":"Kula\u00e7oglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Turan","family":"Turhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yama\u00e7","family":"Taskin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1054\/jocn.1999.0666_RF1","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1073\/pnas.91.2.787","article-title":"The pineal control of aging: the effect of melatonin and pineal grafting on aging mice","volume":"91","author":"Pierpaoli","year":"1994","journal-title":"Proc Natl Acad Sci"},{"key":"10.1054\/jocn.1999.0666_RF2","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1002\/aja.1001620402","article-title":"The mammalian pineal gland: structure and function","volume":"162","author":"Reiter","year":"1981","journal-title":"Am J Anat"},{"key":"10.1054\/jocn.1999.0666_RF3","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/0165-2478(87)90169-6","article-title":"Melatonin: a principal neuroimmunoregulatory and anti-stress hormone: its anti-aging effects","volume":"16","author":"Pierpaoli","year":"1987","journal-title":"Immunol Lett"},{"key":"10.1054\/jocn.1999.0666_RF4","first-page":"1","article-title":"Effect of pinealectomy on immune reactions in the rat","volume":"18","author":"Jankovic","year":"1970","journal-title":"Immunology"},{"key":"10.1054\/jocn.1999.0666_RF5","doi-asserted-by":"crossref","first-page":"321","DOI":"10.3171\/jns.1985.63.3.0321","article-title":"The pineal gland: anatomy, physiology and clinical significance","volume":"63","author":"Erlich","year":"1985","journal-title":"J Neurosurg"},{"key":"10.1054\/jocn.1999.0666_RF6","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/BF01405867","article-title":"The mammalian pineal gland, a survey","volume":"34","author":"Kappers","year":"1976","journal-title":"Acta Neurochir"},{"key":"10.1054\/jocn.1999.0666_RF7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1600-079X.1993.tb00478.x","article-title":"The immunoendocrine role of melatonin","volume":"14","author":"Maestroni","year":"1993","journal-title":"J Pineal Res"},{"key":"10.1054\/jocn.1999.0666_RF8","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/0165-5728(90)90059-V","article-title":"The involvement of pineal gland and melatonin in immunity and aging. I. Thymus-Mediated, Immunoreconstituting and antiviral activity of TRH","volume":"27","author":"Pierpaoli","year":"1990","journal-title":"J Neuroimmunol"},{"key":"10.1054\/jocn.1999.0666_RF9","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0165-5728(94)90029-9","article-title":"The immuno-reconstituting effect of melatonin or pineal grafting and its relation to zinc pool in aging mice","volume":"53","author":"Mocchegiani","year":"1994","journal-title":"J Neuroimmunol"},{"key":"10.1054\/jocn.1999.0666_RF10","first-page":"1200","article-title":"The zinc pool is involved in the immuno-reconstituting effect of melatonin in pinealectomized mice","volume":"277","author":"Mocchegiani","year":"1996","journal-title":"JPET"},{"key":"10.1054\/jocn.1999.0666_RF11","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1111\/j.1749-6632.1991.tb16988.x","article-title":"The role of zinc in neuroendocrineimmune interactions during aging","volume":"621","author":"Fabris","year":"1991","journal-title":"Ann NY Acad sci"},{"key":"10.1054\/jocn.1999.0666_RF12","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/0192-0561(95)00059-B","article-title":"Reversibility of the thymic involution and age-related peripheral immune dysfunctions by zinc supplemantation in old mice","volume":"17","author":"Mocchegiani","year":"1995","journal-title":"Int J Immunopharmacol"},{"key":"10.1054\/jocn.1999.0666_RF13","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1159\/000129471","article-title":"Can the wound healing process be improved by vitamin supplementation. Experimental study on humans","volume":"28","author":"Vaxman","year":"1996","journal-title":"Eur Surg Res"},{"key":"10.1054\/jocn.1999.0666_RF14","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1080\/07315724.1985.10720062","article-title":"Trace elements regulation of immunity and infection","volume":"4","author":"Chandra","year":"1985","journal-title":"Am Coll Nutr"},{"key":"10.1054\/jocn.1999.0666_RF15","doi-asserted-by":"crossref","first-page":"530","DOI":"10.3177\/jnsv.38.Special_530","article-title":"Role of zinc in surgical nutrution","volume":"38 (Suppl)","author":"Nezu","year":"1992","journal-title":"J Nutr Sci Vitaminol"},{"key":"10.1054\/jocn.1999.0666_RF16","first-page":"333","article-title":"Connective tissue repair in zinc deficiency. An ultrastructural morphometric study in performed mesentery in rats","volume":"158","author":"Franzen","year":"1992","journal-title":"Eur J Surg"},{"key":"10.1054\/jocn.1999.0666_RF17","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/j.1600-079X.1990.tb00697.x","article-title":"Alteration of plasma cation levels in rats kept in constant light","volume":"9","author":"Morton","year":"1990","journal-title":"J Pineal Res"},{"key":"10.1054\/jocn.1999.0666_RF18","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/254349a0","article-title":"Influence of the pineal on wound healing","volume":"254","author":"Weichselbaum","year":"1975","journal-title":"Nature"},{"key":"10.1054\/jocn.1999.0666_RF19","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/BF02124114","article-title":"A new technique of pinealectomy for adult rats","volume":"33","author":"Kuszak","year":"1977","journal-title":"Experimentia"},{"key":"10.1054\/jocn.1999.0666_RF20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF01400645","article-title":"Morphological assestment of pinealectomy and fetal pineal gland transplatation in rats. Part 1","volume":"128","author":"Palao#akglu","year":"1994","journal-title":"Acta Neurochir"},{"key":"10.1054\/jocn.1999.0666_RF21","first-page":"224","article-title":"Effect of enhanced macrophage function on early wound healing","volume":"104","author":"Browder","year":"1988","journal-title":"Surgery"},{"key":"10.1054\/jocn.1999.0666_RF22","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0165-5728(93)90079-E","article-title":"Neonatal pinealectomy impairs murine antibody-dependent cellular cytotoxicity","volume":"43","author":"Vermeulen","year":"1993","journal-title":"J Neuroimmunol"},{"key":"10.1054\/jocn.1999.0666_RF23","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1021\/ac60205a053","article-title":"Two improved and simplified methods for the spectrophotometric determination of hydroxyproline","volume":"35","author":"Bergman","year":"1963","journal-title":"Anal Chem"},{"key":"10.1054\/jocn.1999.0666_RF24","first-page":"24","article-title":"Clinical methods for atomic absorption spectroscopy","volume":"3","author":"Fernandez","year":"1971","journal-title":"Clin Chem"},{"key":"10.1054\/jocn.1999.0666_RF25","first-page":"125","article-title":"Effect of macrophage stimulation on collogen biosynthesis in the healing wound","volume":"63","author":"Portera","year":"1997","journal-title":"Am Surg"},{"key":"10.1054\/jocn.1999.0666_RF26","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1007\/BF01400646","article-title":"Behavioral assestment of pinealectomy and fetal pineal gland transplatation in rats. Part 2","volume":"128","author":"Palao#akglu","year":"1994","journal-title":"Acta Neurochir"},{"key":"10.1054\/jocn.1999.0666_RF27","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1001\/archsurg.1996.01430220031006","volume":"131","author":"Biert","year":"1996","journal-title":"Arch Surg"},{"key":"10.1054\/jocn.1999.0666_RF28","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0039-6060(96)80207-8","article-title":"Advanced age alone does not suppress anastomotic healing in the intestine","volume":"119","author":"Stoop","year":"1996","journal-title":"Surgery"},{"key":"10.1054\/jocn.1999.0666_RF29","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1902\/jop.1993.64.5.323","article-title":"Hydroxyproline and total protein levels in gingiva and gingival crevicular fluid in patients with juvenile, rapidly progressive, and adult periodontitis","volume":"64","author":"Akalin","year":"1993","journal-title":"J Periodontol"}],"container-title":["Journal of Clinical Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586899906665?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0967586899906665?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,11]],"date-time":"2019-04-11T14:53:37Z","timestamp":1554994417000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0967586899906665"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,7]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2000,7]]}},"alternative-id":["S0967586899906665"],"URL":"https:\/\/doi.org\/10.1054\/jocn.1999.0666","relation":{},"ISSN":["0967-5868"],"issn-type":[{"value":"0967-5868","type":"print"}],"subject":[],"published":{"date-parts":[[2000,7]]}}}