{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T04:38:17Z","timestamp":1791175097880,"version":"4.1.0"},"reference-count":19,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2000,2,1]],"date-time":"2000-02-01T00:00:00Z","timestamp":949363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Hypotheses"],"published-print":{"date-parts":[[2000,2]]},"DOI":"10.1054\/mehy.1999.0987","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T11:34:15Z","timestamp":1027683255000},"page":"275-277","source":"Crossref","is-referenced-by-count":67,"title":["Helicobacter infection and cirrhosis in hepatitis C virus carriage: is it an innocent bystander or a troublemaker?"],"prefix":"10.1054","volume":"54","author":[{"given":"A.","family":"Ponzetto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Pellicano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Leone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.A.","family":"Cutufia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Turrini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.F.","family":"Grigioni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"D\u2019Errico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Mortimer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Rizzetto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Silengo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1054\/mehy.1999.0987_RF1","series-title":"Diseases of the Liver and Biliary System, 10th edn","article-title":"Hepatic Cirrhosis","author":"Sherlock","year":"1997"},{"key":"10.1054\/mehy.1999.0987_RF2","first-page":"A1173","article-title":"Interferon\u2013ribavirin combination therapy for chronic hepatitis C, type 1 b in a unique Irish cohort 18 years post inoculation","volume":"110","author":"Clarke","year":"1996","journal-title":"Gastroenterology"},{"key":"10.1054\/mehy.1999.0987_RF3","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1002\/hep.510230607","article-title":"The long-term pathological evolution of chronic hepatitis C","volume":"23","author":"Yano","year":"1996","journal-title":"Hepatology"},{"key":"10.1054\/mehy.1999.0987_RF4","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1001\/jama.1991.03460150078027","article-title":"Hepatitis B and C viruses and their interaction in the origin of hepatocellular carcinoma","volume":"265","author":"Kaklamani","year":"1991","journal-title":"JAMA"},{"key":"10.1054\/mehy.1999.0987_RF5","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1053\/gast.1996.v111.pm8698200","article-title":"Hepatitis C virus genotypes and risk of hepatocellular carcinoma in cirrhosis: a case-control study","volume":"111","author":"Silini","year":"1996","journal-title":"Gastroenterology"},{"key":"10.1054\/mehy.1999.0987_RF6","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1002\/hep.510230406","article-title":"The natural course of chronic hepatitis C: a comparison between patients with genotypes 1 and 2 hepatitis C viruses","volume":"23","author":"Kobayashi","year":"1996","journal-title":"Hepatology"},{"key":"10.1054\/mehy.1999.0987_RF7","doi-asserted-by":"crossref","first-page":"2733","DOI":"10.1001\/archinte.1994.00420230126015","article-title":"HLA-DR5. A genetic factor influencing the outcome of hepatitis C virus infection?","volume":"154","author":"Peano","year":"1994","journal-title":"Arch Intern Med"},{"key":"10.1054\/mehy.1999.0987_RF8","first-page":"3","article-title":"Cellular and molecular mechanisms that direct leukocyte traffic","volume":"23","author":"Butcher","year":"1990","journal-title":"Am J Pathol"},{"key":"10.1054\/mehy.1999.0987_RF9","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1016\/0016-5085(94)90550-9","article-title":"Expression of cytokine-dependent immune adhesion molecular by hepatocytes and bile duct cells in chronic hepatitis C","volume":"107","author":"Mosnier","year":"1995","journal-title":"Gastroenterology"},{"key":"10.1054\/mehy.1999.0987_RF10","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1016\/0016-5085(93)90148-6","article-title":"Mechanisms involved in Helicobacter pylori infection","volume":"105","author":"Yoshida","year":"1995","journal-title":"Gastroenterology"},{"key":"10.1054\/mehy.1999.0987_RF11","series-title":"Malignancy and Chronic Inflammation in the Gastrointestinal Tract: New Concepts","first-page":"25","article-title":"Cytokine responses to Helicobacter pylori -induced infection","author":"Crabtree","year":"1995"},{"key":"10.1054\/mehy.1999.0987_RF12","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/S0002-9343(96)00273-2","article-title":"Pathophysiology of Helicobacter pylori -induced gastritis and peptic ulcer disease","volume":"102","author":"Peek","year":"1997","journal-title":"Am J Med"},{"key":"10.1054\/mehy.1999.0987_RF13","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/S0016-5085(98)70422-6","article-title":"Meta-analysis of the relationship between Helicobacter pylori seropositivity and gastric cancer","volume":"114","author":"Huang","year":"1998","journal-title":"Gastroenterology"},{"key":"10.1054\/mehy.1999.0987_RF14","doi-asserted-by":"crossref","first-page":"2024","DOI":"10.1023\/A:1018849930107","article-title":"High prevalence of Helicobacter pylori in liver cirrhosis: relationship with clinical and endoscopic features and the risk of peptic ulcer","volume":"42","author":"Siringo","year":"1997","journal-title":"Dig Dis Sci"},{"key":"10.1054\/mehy.1999.0987_RF15","doi-asserted-by":"crossref","first-page":"2501","DOI":"10.1111\/j.1572-0241.1998.00711.x","article-title":"Epidemiology of peptic ulcer disease in cirrhotic patients: role of Helicobacter pylori","volume":"93","author":"Calvet","year":"1998","journal-title":"Am J Gastroenterol"},{"key":"10.1054\/mehy.1999.0987_RF16","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/S0016-5085(98)70589-X","article-title":"Hepatic Helicobacter species identified in bile and gallbladder tissue from Chileans with chronic cholecystitis","volume":"114","author":"Fox","year":"1998","journal-title":"Gastroenterology"},{"key":"10.1054\/mehy.1999.0987_RF17","first-page":"A103","article-title":"Detection of Helicobacter sp in the liver of patients with hepatocarcinoma","volume":"43","author":"Avenaud","year":"1998","journal-title":"Gut"},{"key":"10.1054\/mehy.1999.0987_RF18","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1093\/jnci\/86.16.1222","article-title":"Chronic active hepatitis and associated liver tumors in mice caused by a persistent bacterial infection with a novel Helicobacter species","volume":"86","author":"Ward","year":"1994","journal-title":"J Natl Cancer Inst"},{"key":"10.1054\/mehy.1999.0987_RF19","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1099\/00222615-42-1-48","article-title":"In-vitro hepatotoxic factor in Helicobacter hepaticus, H. pylori and other Helicobacter species","volume":"42","author":"Taylor","year":"1995","journal-title":"J Med Microbiol"}],"container-title":["Medical Hypotheses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987799909878?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987799909878?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,11]],"date-time":"2019-04-11T18:52:35Z","timestamp":1555008755000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306987799909878"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,2]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2000,2]]}},"alternative-id":["S0306987799909878"],"URL":"https:\/\/doi.org\/10.1054\/mehy.1999.0987","relation":{},"ISSN":["0306-9877"],"issn-type":[{"value":"0306-9877","type":"print"}],"subject":[],"published":{"date-parts":[[2000,2]]}}}