{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,20]],"date-time":"2024-09-20T15:33:07Z","timestamp":1726846387179},"reference-count":21,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Hypotheses"],"published-print":{"date-parts":[[2001,1]]},"DOI":"10.1054\/mehy.2000.1117","type":"journal-article","created":{"date-parts":[[2002,9,19]],"date-time":"2002-09-19T15:33:28Z","timestamp":1032449608000},"page":"91-94","source":"Crossref","is-referenced-by-count":16,"title":["Hypothesized treatment for migraines using low doses of tryptophan, niacin, calcium, caffeine, and acetylsalicylic acid"],"prefix":"10.1054","volume":"56","author":[{"given":"A.","family":"Gedye","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1054\/mehy.2000.1117_RF1","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1001\/archneur.1971.00490030051005","article-title":"Histamine and serotonin in cluster headache","volume":"25","author":"Anthony","year":"1971","journal-title":"Arch Neurol"},{"key":"10.1054\/mehy.2000.1117_RF2","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1136\/jnnp.52.2.182","article-title":"Plasma serotonin in patients with chronic headaches","volume":"52","author":"Anthony","year":"1989","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1054\/mehy.2000.1117_RF3","series-title":"Quinolinic Acid and the Kynurenines","first-page":"241","article-title":"Nutritional aspects of the kynurenine pathway of tryptophan metabolism","author":"Bender","year":"1989"},{"key":"10.1054\/mehy.2000.1117_RF4","series-title":"Compendium of Pharmaceuticals and Specialties 34th Edition.","year":"1999"},{"key":"10.1054\/mehy.2000.1117_RF5","article-title":"Nutrition and Neurotransmitters","author":"Chafetz","year":"1990","journal-title":"The Nutrient Bases of Behavior."},{"key":"10.1054\/mehy.2000.1117_RF6","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1111\/j.1526-4610.1979.hed1903114.x","article-title":"Classification and mechanism of migraine","volume":"19","author":"Dalessio","year":"1979","journal-title":"Headache"},{"key":"10.1054\/mehy.2000.1117_RF7","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1056\/NEJM199108013250504","article-title":"Treatment of migraine attacks with sumatriptan","volume":"325","author":"Ferrari","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1054\/mehy.2000.1117_RF8","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0165-6147(93)90084-W","article-title":"Clinical and experimental effects of sumatriptan in humans","volume":"14","author":"Ferrari","year":"1993","journal-title":"Trends Pharmacol Sci"},{"key":"10.1054\/mehy.2000.1117_RF9","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/BF00964611","article-title":"L-kynurenine, its synthesis and possible regulatory function in brain","volume":"5","author":"Gal","year":"1980","journal-title":"Neurochem Res"},{"key":"10.1054\/mehy.2000.1117_RF10","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0733-8619(05)70293-0","article-title":"(1997) Current concepts of the pathophysiology of migraine","volume":"15","author":"Goadsby","year":"1997","journal-title":"Neurol Clin"},{"key":"10.1054\/mehy.2000.1117_RF11","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1136\/jnnp.64.2.143","article-title":"A triptan too far?","volume":"64","author":"Goadsby","year":"1998","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1054\/mehy.2000.1117_RF12","series-title":"Textbook of Medical Physiology, 8th Edition","author":"Guyton","year":"1991"},{"key":"10.1054\/mehy.2000.1117_RF13","unstructured":"Hendler, S. S. The Doctor\u2019s Vitamin and Mineral Encyclopedia. New York, Simon & Schuster, 1990"},{"key":"10.1054\/mehy.2000.1117_RF14","series-title":"Mechanism and Management of Headache, 5th Edition","author":"Lance","year":"1993"},{"key":"10.1054\/mehy.2000.1117_RF15","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/j.1528-1157.1981.tb04108.x","article-title":"Kynurenines and seizures","volume":"22","author":"Lapin","year":"1991","journal-title":"Epilepsia"},{"key":"10.1054\/mehy.2000.1117_RF16","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1016\/S0002-8223(21)03240-5","article-title":"The effects of caffeine on various body systems","volume":"87","author":"Leonard","year":"1987","journal-title":"J Am Diet Assoc"},{"key":"10.1054\/mehy.2000.1117_RF17","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1111\/j.1526-4610.1994.hed3406319.x","article-title":"An update on the epidemiology of migraine","volume":"34","author":"Lipton","year":"1994","journal-title":"Headache"},{"key":"10.1054\/mehy.2000.1117_RF18","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1136\/jnnp.55.12.1103","article-title":"Sumatriptan: efficacy and contribution to migraine mechanisms","volume":"55","author":"Pearce","year":"1992","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1054\/mehy.2000.1117_RF19","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1038\/clpt.1991.104","article-title":"Tolerance to nicotinic acid flushing","volume":"50","author":"Stern","year":"1991","journal-title":"Clin Pharmacol Ther"},{"key":"10.1054\/mehy.2000.1117_RF20","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1177\/03331024860060S411","article-title":"Naproxen sodium in the treatment of migraine","volume":"6, Suppl 4","author":"Welch","year":"1986","journal-title":"Cephalalgia"},{"key":"10.1054\/mehy.2000.1117_RF21","first-page":"165","article-title":"The effect of aspirin on niacin-induced cutaneous reactions","volume":"34","author":"Whelan","year":"1992","journal-title":"J Fam Pract"}],"container-title":["Medical Hypotheses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987700911174?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987700911174?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T05:28:12Z","timestamp":1682141292000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306987700911174"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,1]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,1]]}},"alternative-id":["S0306987700911174"],"URL":"https:\/\/doi.org\/10.1054\/mehy.2000.1117","relation":{},"ISSN":["0306-9877"],"issn-type":[{"value":"0306-9877","type":"print"}],"subject":[],"published":{"date-parts":[[2001,1]]}}}