{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T01:51:13Z","timestamp":1778032273939,"version":"3.51.4"},"reference-count":18,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2002,4,1]],"date-time":"2002-04-01T00:00:00Z","timestamp":1017619200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Hypotheses"],"published-print":{"date-parts":[[2002,4]]},"DOI":"10.1054\/mehy.2001.1528","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T11:33:30Z","timestamp":1027683210000},"page":"337-339","source":"Crossref","is-referenced-by-count":8,"title":["Minor form of trigonocephaly is an autistic skull shape? A suggestion based on homeobox gene variants andMECP2 mutations"],"prefix":"10.1054","volume":"58","author":[{"given":"S.","family":"Ijichi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Ijichi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1054\/mehy.2001.1528_RF1","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1126\/science.8209254","article-title":"The genetic basis of complex human behaviors","volume":"264","author":"Plomin","year":"1994","journal-title":"Science"},{"key":"10.1054\/mehy.2001.1528_RF2","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1136\/jmg.32.4.269","article-title":"Association study with two markers of a human homeogene in infantile autism","volume":"32","author":"Petit","year":"1995","journal-title":"J Med Genet"},{"key":"10.1054\/mehy.2001.1528_RF3","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1002\/1096-9926(200012)62:6<393::AID-TERA6>3.0.CO;2-V","article-title":"Discovery of allelic variants of HOXA1 and HOXB1: genetic susceptibility to autism spectrum disorders","volume":"62","author":"Ingram","year":"2000","journal-title":"Teratology"},{"key":"10.1054\/mehy.2001.1528_RF4","doi-asserted-by":"crossref","first-page":"5027","DOI":"10.1242\/dev.126.22.5027","article-title":"Mice mutant for both Hoxa1 and Hoxb1 show extensive remodeling of the hindbrain and defects in craniofacial development","volume":"126","author":"Rossel","year":"1999","journal-title":"Development"},{"key":"10.1054\/mehy.2001.1528_RF5","first-page":"19","article-title":"Jr. Craniofacial disorders caused by mutations in homeobox genes MSX1 and MSX2","volume":"20","author":"Cohen M.","year":"2000","journal-title":"J Craniofac Genet Dev Biol"},{"key":"10.1054\/mehy.2001.1528_RF6","first-page":"663","article-title":"Otx and Emx homeobox genes in brain development","volume":"44","author":"Cecchi","year":"2000","journal-title":"Int J Dev Biol"},{"key":"10.1054\/mehy.2001.1528_RF7","first-page":"619","article-title":"Multiple functions of Dlx genes","volume":"44","author":"Merlo","year":"2000","journal-title":"Int J Dev Biol"},{"key":"10.1054\/mehy.2001.1528_RF8","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1007\/BF00947081","article-title":"Molecular genetics of craniosynostotic syndromes","volume":"235","author":"Muller","year":"1997","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1054\/mehy.2001.1528_RF9","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1002\/1096-8628(20001211)95:4<339::AID-AJMG9>3.0.CO;2-B","article-title":"Head circumference is an independent clinical finding associated with autism","volume":"95","author":"Miles","year":"2000","journal-title":"Am J Hum Genet"},{"key":"10.1054\/mehy.2001.1528_RF10","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1002\/1096-8628(20001211)95:4<339::AID-AJMG9>3.0.CO;2-B","article-title":"Head circumference is an independent clinical finding associated with autism","volume":"95","author":"Miles","year":"2000","journal-title":"Am J Hum Genet"},{"key":"10.1054\/mehy.2001.1528_RF11","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1038\/85970","article-title":"Rett syndrome model suggests MECP2 gives neurons the quiet they need to think","volume":"4","author":"Carter","year":"2001","journal-title":"Nat Neurosci"},{"key":"10.1054\/mehy.2001.1528_RF12","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1038\/13751","article-title":"Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2","volume":"23","author":"Amir","year":"1999","journal-title":"Nat Genet"},{"key":"10.1054\/mehy.2001.1528_RF13","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1086\/302690","article-title":"Rett syndrome and beyond: recurrent spontaneous and familial MECP2 mutations at CpG hotspots","volume":"65","author":"Wan","year":"1999","journal-title":"Am J Hum Genet"},{"key":"10.1054\/mehy.2001.1528_RF14","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1136\/jmg.38.4.224","article-title":"Angelman syndrome phenotype associated with mutations in MECP2, a gene encoding a methyl CpG binding protein","volume":"38","author":"Watson","year":"2001","journal-title":"J Med Genet"},{"key":"10.1054\/mehy.2001.1528_RF15","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/S0140-6736(00)02661-1","article-title":"Somatic mutation in MECP2 as a non-fatal neurodevelopmental disorder in males","volume":"356","author":"Clayton-Smith","year":"2000","journal-title":"Lancet"},{"key":"10.1054\/mehy.2001.1528_RF16","first-page":"43","article-title":"Trigonocephaly associated with symptoms: mainly nonsyndromic type","volume":"25","author":"Shimoji","year":"2000","journal-title":"Nervous System in Children (Syoni-no-noshinkei)"},{"key":"10.1054\/mehy.2001.1528_RF17","first-page":"411","article-title":"Trigonocephaly associated with symptoms: indication of surgical treatment","volume":"25","author":"Ijichi","year":"2000","journal-title":"Nervous System in Children (Syoni-no-noshinkei)"},{"key":"10.1054\/mehy.2001.1528_RF18","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1007\/BF00366148","article-title":"Consensus: trigonocephaly","volume":"12","author":"Collmann","year":"1996","journal-title":"Child's Nerv Syst"}],"container-title":["Medical Hypotheses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987701915282?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306987701915282?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,16]],"date-time":"2021-05-16T07:12:47Z","timestamp":1621149167000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306987701915282"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,4]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2002,4]]}},"alternative-id":["S0306987701915282"],"URL":"https:\/\/doi.org\/10.1054\/mehy.2001.1528","relation":{},"ISSN":["0306-9877"],"issn-type":[{"value":"0306-9877","type":"print"}],"subject":[],"published":{"date-parts":[[2002,4]]}}}