{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T19:44:01Z","timestamp":1788810241146,"version":"build-2803163510"},"reference-count":34,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2001,4,1]],"date-time":"2001-04-01T00:00:00Z","timestamp":986083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2001,4,1]],"date-time":"2001-04-01T00:00:00Z","timestamp":986083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Tissue and Cell"],"published-print":{"date-parts":[[2001,4]]},"DOI":"10.1054\/tice.2000.0169","type":"journal-article","created":{"date-parts":[[2002,9,19]],"date-time":"2002-09-19T11:33:28Z","timestamp":1032435208000},"page":"178-188","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"title":["Cytological effects of experimental exposure to Hg on the gill epithelium of the European flat oyster Ostrea edulis: ultrastructural and quantitative changes related to bioaccumulation"],"prefix":"10.1054","volume":"33","author":[{"given":"M.","family":"Bigas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Durfort","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Poquet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1054\/tice.2000.0169_BIB1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/BF00392739","article-title":"Contribution to the ecotoxicological study of cadmium copper and zinc in the mussel Mytilus edulis","volume":"92","author":"Amiard-Triquet,","year":"1986","journal-title":"Mar. Biol.,"},{"key":"10.1054\/tice.2000.0169_BIB2","doi-asserted-by":"crossref","first-page":"133","DOI":"10.3354\/meps137133","article-title":"Mucocyte distribution and relationship to particle transport on the pseudolamellibranch gill of Crassostrea virginica (Bivalvia: Ostreidae)","volume":"137","author":"Beninger,","year":"1996","journal-title":"Mar. Ecol. Progr. Ser.,"},{"key":"10.1054\/tice.2000.0169_BIB3","first-page":"277","article-title":"Sublethal effects of experimental exposure to mercury in European flat oyster, Ostrea edulis: cell alterations and quantitative analysis of metal","volume":"10","author":"Bigas,","year":"1997","journal-title":"Bio Metals.,"},{"key":"10.1054\/tice.2000.0169_BIB4","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1054\/tice.1999.0021","article-title":"The ultrastructural effect and subcellular localization of mercuric chloride and metylmercuric in insect cells (Aedes albopictus C6\/36)","volume":"31","author":"Braeckman,","year":"1999","journal-title":"Tissue & Cell,"},{"key":"10.1054\/tice.2000.0169_BIB5","article-title":"Cellular biomarkers as useful tools in the biological monitoring of environmental pollution: molluscan digestive lysosomes","author":"Cajaraville,","year":"1995"},{"key":"10.1054\/tice.2000.0169_BIB6","first-page":"131","article-title":"Bioaccumulation and distribution of mercury in the hard clam, Meretrix lusoria (Bivalvia: Venidae)","volume":"106C","author":"Chin,","year":"1993","journal-title":"Comp. Biochem. Physiol.,"},{"key":"10.1054\/tice.2000.0169_BIB7","first-page":"141","article-title":"Ultrastructural characterization of the gill epithelium of Tapes decussatus, L. (Mollusca, Bivalvia)","volume":"8","author":"Durfort,","year":"1988","journal-title":"Iberus"},{"key":"10.1054\/tice.2000.0169_BIB8","first-page":"43","article-title":"Anomal\u0131́as morfol\u00f3gicas de los cilios de las mucosas digestivas de la ostra Crassostrea gigas (Mollusca, Bivalvia)","volume":"VI","author":"Durfort,","year":"1990","journal-title":"Histolog\u0131́a M\u00e9dica,"},{"key":"10.1054\/tice.2000.0169_BIB9","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1007\/BF00212328","article-title":"Paddle cilia and discocilia \u2013 genuine structures?","volume":"192","author":"Ehlers,","year":"1978","journal-title":"Cell. Tiss. Res.,"},{"key":"10.1054\/tice.2000.0169_BIB10","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/BF00397934","article-title":"Gill ultrastructure and symbiotic bacteria in Codakia orbicularis (Bivalvia, Lucinidae)","volume":"115","author":"Frenkiel,","year":"1995","journal-title":"Zoomorphology,"},{"key":"10.1054\/tice.2000.0169_BIB11","series-title":"Ultrastructural pathology of the cell and matrix.","author":"Ghadially,","year":"1997"},{"key":"10.1054\/tice.2000.0169_BIB12","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0025-326X(75)90271-4","article-title":"Mussel watch \u2013 a first step in global marine monitoring","volume":"6","author":"Goldberg,","year":"1975","journal-title":"Mar. Pollut. Bull.,"},{"key":"10.1054\/tice.2000.0169_BIB13","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/S0025-326X(99)00119-8","article-title":"The effects of mercury exposure on the surface morphology of gill filaments in Perna perna (Mollusca: Bivalvia)","volume":"39","author":"Gregory,","year":"1999","journal-title":"Mar. Poll. Bull.,"},{"key":"10.1054\/tice.2000.0169_BIB14","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1365-2818.1985.tb02607.x","article-title":"Stereological estimation of the volume-weighted mean volume of arbitrary particles observed on random sections","volume":"138","author":"Gundersen,","year":"1985","journal-title":"J. Micros.,"},{"key":"10.1054\/tice.2000.0169_BIB15","first-page":"341","article-title":"Toxic effects of zinc on the common mussel Mytilus edulis L (Bivalvia) in brackish water. I. Physiological and histopathological studies","volume":"25","author":"Hietanen,","year":"1988","journal-title":"Ann. Zool. Fennici.,"},{"key":"10.1054\/tice.2000.0169_BIB16","first-page":"41","article-title":"Secretory cell hyperplasia and modification of intracellular glycoprotein in rat airways induced by short periods of exposure to tobacco smoke, and the effect of the antiinflamatory agent phenylmethyloxadiazole","volume":"39","author":"Jones,","year":"1978","journal-title":"Lab. Invest.,"},{"key":"10.1054\/tice.2000.0169_BIB17","first-page":"233","article-title":"Metal handling strategies in molluscs","author":"Langston,","year":"1998"},{"key":"10.1054\/tice.2000.0169_BIB18","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/BF00391199","article-title":"New observations of the gills of Placopecten magellanicus (Mollusca: Bivalvia), and implications for nutrition","volume":"98","author":"Le Pennec,","year":"1988","journal-title":"Marine Biology,"},{"key":"10.1054\/tice.2000.0169_BIB19","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/BF01061089","article-title":"Effects of air pollution on passerine birds and small mammals","volume":"24","author":"Llacuna,","year":"1993","journal-title":"Arch. Environ. Contam. Toxicol.,"},{"key":"10.1054\/tice.2000.0169_BIB20","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/BF02440187","article-title":"Cellular distribution of cadmium in the common winkle Littorina littorea (L) determined by X-ray microscope analysis and histochemistry","volume":"94","author":"Marigomez,","year":"1990","journal-title":"Histochemistry,"},{"key":"10.1054\/tice.2000.0169_BIB21","unstructured":"Marinozzi, V. 1968, Phosphotungstic acid (PTA) as a stain for polysaccharides and glycoproteins in electron microscopy. 2, 55, 56"},{"key":"10.1054\/tice.2000.0169_BIB22","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1017\/S0025315400030368","article-title":"The ultrastructural localization of metals in specimens of Littorina littorea collected from clean and polluted sites","volume":"64","author":"Masson,","year":"1984","journal-title":"J. Mar. Biol. Ass. U.K.,"},{"key":"10.1054\/tice.2000.0169_BIB23","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1017\/S0025315400049195","article-title":"Cadmium and the phosphate granules in Littorina littorea","volume":"69","author":"Nott,","year":"1989","journal-title":"J. Mar. Biol. Ass. U.K.,"},{"key":"10.1054\/tice.2000.0169_BIB24","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/S0040-8166(98)80080-3","article-title":"Ultrastructural changes in fish gills as biomarker to assess small stream pollution","volume":"30","author":"Pawert,","year":"1998","journal-title":"Tissue & Cell,"},{"key":"10.1054\/tice.2000.0169_BIB25","series-title":"Quantitative Aquatic Biological Indicators Are Used to Monitor Trace Metal and Organochlorine Pollution","author":"Phillips,","year":"1980"},{"key":"10.1054\/tice.2000.0169_BIB26","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1007\/BF02027023","article-title":"The uptake of mercuric chloride from sea water by Serranus cabrilla","volume":"22","author":"Radoux,","year":"1979","journal-title":"Bul. Contam. Toxic.,"},{"key":"10.1054\/tice.2000.0169_BIB27","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1083\/jcb.17.1.208","article-title":"The use of the lead citrate at high pH as an electron opaque stain in electron microscopy","volume":"17","author":"Reynolds,","year":"1963","journal-title":"J. Cell. Biol.,"},{"key":"10.1054\/tice.2000.0169_BIB28","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1083\/jcb.47.2.468","article-title":"The cell junction in a lamellibranch gill ciliated epithelium: localization of pyroantimoniate precipitate","volume":"478","author":"Satir,","year":"1970","journal-title":"J. Cell Biol.,"},{"key":"10.1054\/tice.2000.0169_BIB29","doi-asserted-by":"crossref","first-page":"679","DOI":"10.2307\/1540190","article-title":"The effect of copper (II) on survival, respiration, and heart rate in the common blue mussel, Mytilus edulis","volume":"143","author":"Scott,","year":"1972","journal-title":"Biol. Bull. Mar. Biol. Lab., Woods Hole"},{"key":"10.1054\/tice.2000.0169_BIB30","doi-asserted-by":"crossref","first-page":"127","DOI":"10.3354\/meps125127","article-title":"Bioavailable heavy metals in estuarine waters as assessed by metal shell-weight indices in sentinel musssels Mytilus galloprovincialis","volume":"125","author":"Soto,","year":"1995","journal-title":"Mar. Ecol. Prog. Ser.,"},{"key":"10.1054\/tice.2000.0169_BIB31","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1365-2818.1984.tb02501.x","article-title":"The unbiased estimation of number and sizes of arbitrary particles using the disector","volume":"134","author":"Sterio,","year":"1984","journal-title":"Journal of Microscopy,"},{"key":"10.1054\/tice.2000.0169_BIB32","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0022-2011(86)90040-6","article-title":"Chronic histopatological effects of short-term copper and cadmium exposure on the gill of the mussel Mytilus edulis","volume":"47","author":"Sunila,","year":"1986","journal-title":"J. Invert. Pathol.,"},{"key":"10.1054\/tice.2000.0169_BIB33","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0022-2011(88)90112-7","article-title":"Acute histological responses of the gill of the mussel Mytilus edulis, to exposure by environmental pollutants","volume":"52","author":"Sunila,","year":"1988","journal-title":"J. Invert. Pathol.,"},{"key":"10.1054\/tice.2000.0169_BIB34","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0141-1136(85)90137-0","article-title":"Trace metals in Chesapeake bay oysters. Intra-sample variability and its implications for biomonitoring","volume":"16","author":"Wright,","year":"1985","journal-title":"Mar. Environ. Res.,"}],"container-title":["Tissue and Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0040816600901691?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0040816600901691?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T20:05:26Z","timestamp":1758571526000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0040816600901691"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,4]]},"references-count":34,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001,4]]}},"alternative-id":["S0040816600901691"],"URL":"https:\/\/doi.org\/10.1054\/tice.2000.0169","relation":{},"ISSN":["0040-8166"],"issn-type":[{"value":"0040-8166","type":"print"}],"subject":[],"published":{"date-parts":[[2001,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cytological effects of experimental exposure to Hg on the gill epithelium of the European flat oyster Ostrea edulis: ultrastructural and quantitative changes related to bioaccumulation","name":"articletitle","label":"Article Title"},{"value":"Tissue and Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1054\/tice.2000.0169","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2001 Harcourt Publishers Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}