{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T22:24:20Z","timestamp":1765232660874},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"24","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dtsch med Wochenschr"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Was ist neu?<\/jats:title><jats:p>\n          Therapiestudien\u2002Fortschritte im Verst\u00e4ndnis der Pathophysiologie des prim\u00e4ren Sj\u00f6gren-Syndroms und die Erarbeitung von Aktivit\u00e4tscores f\u00fchrten zur Entwicklung und Erprobung neuer Therapieans\u00e4tze. Aktuell laufen mindestens 17 kontrollierte Studien beim prim\u00e4ren Sj\u00f6gren-Syndrom.<\/jats:p><jats:p>\n          Fr\u00fcherkennung\u2002Neue Klassifikationskriterien wurden etabliert, mit denen die Erkrankung schon im Fr\u00fchstadium und bei extraglandul\u00e4ren Manifestationen erfasst werden kann. Die Sonografie der Speicheldr\u00fcsen bietet weiteres Potenzial f\u00fcr die Verbesserung der Sensitivit\u00e4t der Diagnostik.<\/jats:p>","DOI":"10.1055\/a-0547-1025","type":"journal-article","created":{"date-parts":[[2018,12,3]],"date-time":"2018-12-03T18:31:16Z","timestamp":1543861876000},"page":"1778-1782","source":"Crossref","is-referenced-by-count":4,"title":["Sj\u00f6gren-Syndrom: fr\u00fcher diagnostizieren, wirksam behandeln"],"prefix":"10.1055","volume":"143","author":[{"given":"Torsten","family":"Witte","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Immunologie und Rheumatologie der Medizinischen Hochschule Hannover"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2018,12,3]]},"container-title":["DMW - Deutsche Medizinische Wochenschrift"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-0547-1025.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,12,3]],"date-time":"2018-12-03T18:31:22Z","timestamp":1543861882000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-0547-1025"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":0,"journal-issue":{"issue":"24","published-online":{"date-parts":[[2018,12,3]]},"published-print":{"date-parts":[[2018,12]]}},"URL":"https:\/\/doi.org\/10.1055\/a-0547-1025","relation":{},"ISSN":["0012-0472","1439-4413"],"issn-type":[{"value":"0012-0472","type":"print"},{"value":"1439-4413","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12]]}}}